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Alexander Rosenberg
Associate Professor
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E-mail
afr@uab.edu
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Alexander Rosenberg
Associate Professor
Positions
Scientist (C)
,
Informatics Institute
,
School of Medicine
2017 -
Associate Professor (P)
,
Microbiology
,
Academic Joint Departments
2017 -
Scientist (C)
,
Center for Clinical and Translational Science (CCTS)
,
General Clinical Research Center
2020 -
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
Filter
Year
Title
Altmetric
2018
A highly potent and broadly neutralizing H1 influenza-specific human monoclonal antibody
.
Scientific Reports
. 8.
2018
2018
Visualizing nationwide variation in medicare Part D prescribing patterns
.
BMC Medical Informatics and Decision Making
. 18.
2018
2018
Understanding B-cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B-cell immunomics approach
.
Immunological Reviews
. 284:120-131.
2018
2018
Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure
2018
2018
Identification of GB1, a gene whose constitutive overexpression increases glycinebetaine content in maize and soybean
.
Plant Direct
. 2.
2018
2017
Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness
.
Scientific Reports
. 7.
2017
2017
Properties of healthcare teaming networks as a function of network construction algorithms
.
PLoS ONE
. 12:e0175876-e0175876.
2017
2017
Pre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Envspecific antibody response in SHIV-infected rhesus macaques
.
PLoS ONE
. 12.
2017
2016
Increased Steady-State Memory B Cell Subsets among High-Risk Participants in an HIV Vaccine Trial
.
AIDS Research and Human Retroviruses
. 32:1143-1148.
2016
2016
Regulatory T Cell Numbers in Inflamed Skin Are Controlled by Local Inflammatory Cues That Upregulate CD25 and Facilitate Antigen-Driven Local Proliferation
.
Journal of Immunology
. 197:2208-2218.
2016
2016
Humoral dysregulation associated with increased systemic inflammation among injection heroin users
.
PLoS ONE
. 11.
2016
2016
Follicular lymphoma tregs have a distinct transcription profile impacting their migration and retention in the malignant lymph node
.
PLoS ONE
. 11.
2016
2016
Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes
.
PLoS ONE
. 11:e0147236-e0147236.
2016
2016
Competitive SWIFT cluster templates enhance detection of aging changes
2016
2016
Identification of significant B cell associations with undetected observations using a Tobit model
.
Statistics and Its Interface
. 9:79-91.
2016
2015
Longitudinal Studies of a B Cell-Derived Signature of Tolerance in Renal Transplant Recipients
.
American Journal of Transplantation
. 15:2908-2920.
2015
2015
A Diagnostic Serum Antibody Test for Patients With Staphylococcus aureus Osteomyelitis
.
Clinical Orthopaedics and Related Research
. 473:2735-2749.
2015
2015
Long-Lived Plasma Cells Are Contained within the CD19
-
CD38
hi
CD138
+
Subset in Human Bone Marrow
.
Immunity
. 43:132-145.
2015
2015
Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus
.
Nature Immunology
. 16:755-765.
2015
2014
Divergent Gene Activation in Peripheral Blood and Tissues of Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis following Infliximab Therapy
.
PLoS ONE
. 9:e110657-e110657.
2014
2014
Primary Sjögren's Syndrome Is Characterized by Distinct Phenotypic and Transcriptional Profiles of IgD+ Unswitched Memory B Cells
.
Arthritis and Rheumatology
. 66:2558-2569.
2014
2014
Neutrophil-Mediated IFN Activation in the Bone Marrow Alters B Cell Development in Human and Murine Systemic Lupus Erythematosus
.
Journal of Immunology
. 192:906-918.
2014
2013
Inflammation-induced interstitial migration of effector CD4
+
T cells is dependent on integrin α v
.
Nature Immunology
. 14:949-958.
2013
2013
IL-4 Attenuates Th1-Associated Chemokine Expression and Th1 Trafficking to Inflamed Tissues and Limits Pathogen Clearance
.
PLoS ONE
. 8.
2013
2013
9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles
.
PLoS ONE
. 8.
2013
2012
Advances in human B cell phenotypic profiling
.
Frontiers in Immunology
. 3.
2012
2012
9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity
.
PLoS ONE
. 7.
2012
2012
Syk inhibition with fostamatinib leads to transitional B lymphocyte depletion
.
Clinical Immunology
. 142:237-242.
2012
2012
Multiparameter flow cytometry and bioanalytics for B cell profiling in systemic lupus erythematosus
.
Methods in Molecular Biology
. 900:109-134.
2012
2011
Decreased influenza-specific B cell responses in rheumatoid arthritis patients treated with anti-tumor necrosis factor
2011
2011
Follicular lymphoma tumor-infiltrating T-helper (T
H
) cells have the same polyfunctional potential as normal nodal T
H
cells despite skewed differentiation
.
Blood
. 118:3591-3602.
2011
2011
Multifaceted intervention by the hsp90 inhibitor ganetespib (sta-9090) in cancer cells with activated jak/stat signaling
.
PLoS ONE
. 6.
2011
1998
Analysis of direction-tuning curves of neurons in the turtle's accessory optic system
.
Experimental Brain Research
. 121:361-370.
1998
1996
A model for optokinetic eye movements in turtles that incorporates properties of retinal-slip neurons
.
Visual Neuroscience
. 13:375-383.
1996
1993
Visual-response properties of units in the turtle cerebellar granular layer in vitro
.
Journal of Neurophysiology
. 69:1314-1322.
1993
1991
Effects Of Synaptic Drugs On Turtle Optokinetic Nystagmus And The Spike Responses Of The Basal Optic Nucleus
.
Visual Neuroscience
. 7:431-440.
1991
1991
Electrophysiological evidence for a direct projection of direction-sensitive retinal ganglion cells to the turtle's accessory optic system
.
Journal of Neurophysiology
. 65:1022-1033.
1991
1990
Retinal direction-sensitive input to the accessory optic system: an in vitro approach with behavioral relevance
.
Brain Research
. 522:161-164.
1990
1990
Visual-response properties of neurons in turtle basal optic nucleus in vitro
.
Journal of Neurophysiology
. 63:1033-1045.
1990
Research
Principal Investigator On
Tissue and Organ Specific Human B Cell Immunity - Core D: Data Analytics and Bioinformatics Core
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2019 - 2024
Development of Mucosal and Systemic Immunity and Risk of Food Allergy
awarded by
University of Rochester
2017 - 2022
Modeling Mechanisms of Adjuvanated Influenza Vaccine Induced IgG Repertoire Diversity and Heterosubtypic Immunity URF (AWD00001405)
awarded by
University of Rochester
2018 - 2022
Targeting Tonsillar B Cells For The Induction of Effective Mucosal Immunity to HIV
awarded by
University of Rochester
2017 - 2019
Targeting IgM Memory to Establish Protective B Cell Responses to HIV URF Award No: AWD0000083
awarded by
University of Rochester
2017 - 2018
Investigator On
Origin and Function of Double Negative T Cells in Lupus
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2020 - 2025
TLR7 and TLR9-Directed Plasma Cell Formation: Dissecting the Molecular Basis for their Differential Dependence on IFN-Induced Signals
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2020 - 2025
Molecular Analysis and Lineage Tracing of Influenza-Specific, Lung-Resident Memory B Cells
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2020 - 2025
Pathogenic Autoantibodies with Specificity for Aberrant Glycoproteins: Assessment of a Therapeutic Target in an Autoimmune Disease
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2020 - 2025
Regulation of T Cell Responses to Allergens and Environmental Microbes
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2020 - 2025
Identification and Characterization of Effector Memory B Cell Populations That Dominate Memory Responses to Subsequent Influenza Infection and Vaccination
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2020 - 2024
Tissue and Organ Specific Human B Cell Immunity
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2019 - 2024
Tissue and Organ Specific Human B Cell Immunity - Project 2: Characterization of Virus-Specific Human B Cell Subsets in Lymphoid and Non-Lymphoid Tissues
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2019 - 2024
Dynamics of the Protective Vaccine-Induced Human Influenza Neuraminidase B Cell Response
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2019 - 2023
Targeting Tonsillar B Cells for the Induction of Effective Mucosal Immunity to HIV
awarded by
National Institute of Dental and Craniofacial Research/NIH/DHHS
2019 - 2022
Resident Cardiac Macrophage Dysfunction and Pneumonia-Associated Adverse Cardiac Events
awarded by
American Heart Association
2018 - 2021
Origin and Function of Double Negative T Cells in Lupus
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2020
Virus-Induced Cell Fate Decisions in Anti-Viral Immunity
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2014 - 2020
Virus-induced Cell Fate Decisions in Anti-Viral Immunity - Administrative Supplement
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
2014 - 2020
Targeting IgM Memory to Establish Protective B Cell Responses to HIV
awarded by
University of Rochester Medical Center
2019 - 2020
Teaching
Teaching Activities
INFO510 - Programming w/Biological Data (Summer Term 2020)
2020
INFO510 - Programming w/Biological Data (Summer Term 2019)
2019
INFO510 - Programming w/Biological Data (Summer Term 2018)
2018
Background
Education And Training
Doctor of Philosophy in Neuroscience,
University of Pittsburgh
1993
Bachelor of Engineering in Electrical, Electronics and Communications Engineering,
University of Delaware
1987
Contact
Full Name
Alexander
Rosenberg