Positions

Overview

  • Dr. Ambika Ashraf is the division director of Pediatric Endocrinology at UAB, Ralph Frohsin Endowed Chair in Pediatric Endocrinology. She is a professor in the Department of Pediatrics. She earned her medical degree from the Calicut University, Kerala, India. Subsequently, she completed pediatric residency and pediatric endocrinology fellowship at the Children’s Hospital, the University of Alabama at Birmingham. She is board certified in Pediatrics, Pediatric Endocrinology and also in Clinical Lipidology. She serves as the Director of the Pediatric Lipid Clinic, Associate Director of Metabolic Bone Clinic at Children’s of Alabama, and an Associate Director of the UAB Comprehensive Diabetes Center. Dr. Ashraf is a member of multiple professional societies, including the American Academy of Pediatrics, Pediatric Endocrine Society, ASBMR, Society for Pediatric Research and National Lipid Association. Dr. Ashraf is active in clinical research investigating lipid, bone and mineral homeostasis, and diabetes. Dr. Ashraf also serves on the sub-board of Endocrinology for the American Board of Pediatrics.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Improving Long-Term Outcomes of Youth With Lipid Abnormalities-Expanding the Role of Pediatric EndocrinologistsJournal of Clinical Endocrinology and Metabolism.  104:4421-4426. 2019
    2019 Higher hemoglobin A1C and atherogenic lipoprotein profiles in children and adolescents with type 2 diabetes mellitusJournal of Clinical and Translational Endocrinology.  15:30-34. 2019
    2019 Bile Acid Synthesis Disorder Masquerading as Intractable Vitamin D-Deficiency Rickets.Journal of the Endocrine Society.  3:397-402. 2019
    2019 Glycemic control and lipid outcomes in children and adolescents with type 2 diabetesPLoS ONE.  14. 2019
    2019 Temporal trends in incidence of pediatric type 1 diabetes in Alabama: 2000-2017Pediatric Diabetes2019
    2018 Clinical characteristics and sequelae of severe hypertriglyceridemia in pediatricsEndocrine Practice.  24:789-795. 2018
    2018 Dyslipidemia is associated with pediatric nonalcoholic fatty liver diseaseJournal of Clinical Lipidology.  12:981-987. 2018
    2018 Pathophysiology of Type 2 diabetes in Children and Adolescents.Current Diabetes Reviews2018
    2018 Impact of vitamin D treatment on 25 hydroxy vitamin D levels and insulin homeostasis in obese African American adolescents in a randomized trialJournal of Clinical and Translational Endocrinology.  12:13-19. 2018
    2018 Effectiveness of a carbohydrate restricted diet to treat non-alcoholic fatty liver disease in adolescents with obesity: Trial design and methodologyControlled Clinical Trials.  68:95-101. 2018
    2018 An Unusual Case of Galactorrhea With Normal Serum ProlactinClinical Pediatrics.  57:238-240. 2018
    2017 Hospital management of severe hypertriglyceridemia in childrenCurrent Pediatric Reviews.  13:225-231. 2017
    2017 Approach to hypertriglyceridemia in the pediatric populationPediatrics in Review.  38:424-434. 2017
    2017 Extreme hypertriglyceridemia, pseudohyponatremia, and pseudoacidosis in a neonate with lipoprotein lipase deficiency due to segmental uniparental disomyJournal of Clinical Lipidology.  11:757-762. 2017
    2017 Effect of prenatal versus postnatal Vitamin D deficiency on pulmonary structure and function in miceAmerican Journal of Respiratory Cell and Molecular Biology.  56:383-392. 2017
    2016 Body mass index and glycemic control influence lipoproteins in children with type 1 diabetesJournal of Clinical Lipidology.  10:1240-1247. 2016
    2016 Overweight adolescents with type 2 diabetes have significantly higher lipoprotein abnormalities than those with type 1 diabetesDiabetes Research and Clinical Practice.  115:83-89. 2016
    2016 Rhabdomyolysis in Pediatric Patients With Diabetic Ketoacidosis or Hyperglycemic Hyperosmolar State: A Case Series.Global Pediatric Health.  3:2333794X16671391. 2016
    2015 Feasibility and efficacy of diabetic retinopathy screening among youth with diabetes in a pediatric endocrinology clinic: A cross-sectional studyDiabetology & Metabolic Syndrome.  7. 2015
    2015 Diabetes and prediabetes are significantly higher in morbidly obese children compared with obese childrenEndocrine Practice.  21:1046-1053. 2015
    2015 Metformin treatment improves weight and dyslipidemia in children with metabolic syndromeJournal of Pediatric Endocrinology and Metabolism.  28:649-655. 2015
    2015 Bone mineral content as a driver of energy expenditure in prepubertal and early pubertal boysJournal of Pediatrics.  166:1397-1403. 2015
    2015 Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individualsJournal of Clinical and Translational Endocrinology.  2:77-82. 2015
    2015 Diabetes status and race are associated with cardiovascular risk markers in obese adolescentsEndocrine Practice.  21:165-173. 2015
    2015 Fibroblast growth factor-21, body composition, and insulin resistance in pre-pubertal and early pubertal males and femalesClinical Endocrinology.  82:550-556. 2015
    2014 Associations between vascular health indices and serum total, free and bioavailable 25-hydroxyvitamin D in adolescentsPLoS ONE.  9. 2014
    2014 Insulin resistance indices are inversely associated with vitamin D binding protein concentrationsJournal of Clinical Endocrinology and Metabolism.  99:178-183. 2014
    2013 Vitamin D and calcium-sensing receptor polymorphisms differentially associate with resting energy expenditure in peripubertal childrenJournal of Bone and Mineral Metabolism.  31:695-702. 2013
    2013 Glycemic control and diabetic dyslipidemia in adolescents with type 2 diabetesEndocrine Practice.  19:972-979. 2013
    2013 Higher Serum Insulin Concentrations Positively Influence the Bone Mineral Density in African American Adolescents.British Journal of Medicine and Medical Research.  3:1050-1061. 2013
    2013 Subclinical Indication of Linkage between Markers of Skeletal and Cardiovascular PropertiesBone Research.  1:291-297. 2013
    2013 Parental perspectives of diabetes management in Alabama public schoolsSouthern Medical Journal.  106:274-279. 2013
    2013 BMI but Not Race Contributes to Vitamin D-Parathyroid Hormone Axis in Peripubertal GirlsICAN: Infant, Child, and Adolescent Nutrition.  5:100-105. 2013
    2013 The role of the C2 gas in the emergence of C60 from the condensing carbon vapourCzechoslovak Journal of Physics.  67. 2013
    2013 Invasive giant prolactinoma presenting as a nasal polypJournal of Pediatrics.  162. 2013
    2012 Associations of C-reactive protein to indices of vascular health and the influence of serum 25(OH)D status in healthy adultsJournal of Nutrition and Metabolism.  2012. 2012
    2012 Macronutrient intake influences the effect of 25-hydroxy-vitamin D status on metabolic syndrome outcomes in african american girlsCholesterol.  2012. 2012
    2012 Calcium homeostasis may influence resting energy expenditure with effects most apparent in early pubertal girlsActa Paediatrica.  101. 2012
    2012 Hypercalcemic crisis induced by calcium carbonateClinical Kidney Journal.  5:288-291. 2012
    2012 Serum 25-hydroxyvitamin D and Ethnic Differences in Arterial Stiffness and Endothelial Function.Journal of Clinical Medicine Research.  4:197-205. 2012
    2011 Associations of serum 25-hydroxyvitamin d and components of the metabolic syndrome in obese adolescent femalesObesity Research.  19:2214-2221. 2011
    2011 Type 1 hyperlipoproteinemia and recurrent acute pancreatitis due to lipoprotein lipase antibody in a young girl with Sjögren's syndromeJournal of Clinical Endocrinology and Metabolism.  96:3302-3307. 2011
    2011 Changes in plasma FGF23 in growth hormone deficient children during rhGH therapyJournal of Pediatric Endocrinology and Metabolism.  24:645-650. 2011
    2010 Role of vitamin D in insulin secretion and insulin sensitivity for glucose homeostasisInternational Journal of Endocrinology.  2010. 2010
    2010 Serum 25-hydroxyvitamin D and parathyroid hormone are independent determinants of whole-body insulin sensitivity in women and may contribute to lower insulin sensitivity in African AmericansAmerican Journal of Clinical Nutrition.  92:1344-1349. 2010
    2010 Dietary iron intake in the first 4 months of infancy and the development of type 1 diabetes: A pilot studyDiabetology & Metabolic Syndrome.  2. 2010
    2009 Racial disparities on glycemic control and lipid profiles in children with type 1 diabetesClinical Medicine Insights: Endocrinology and Diabetes.  2009:1-6. 2009
    2009 Threshold for effects of vitamin D deficiency on glucose metabolism in obese female African-American adolescentsJournal of Clinical Endocrinology and Metabolism.  94:3200-3206. 2009
    2007 Insulin treatment reduces pre-prandial plasma ghrelin concentrations in children with type 1 diabetesMedical Science Monitor.  13. 2007
    2007 Nutritional vitamin D deficiency presenting as hemichoreaJournal of Child Neurology.  22:74-76. 2007
    2006 Permanent exocrine and endocrine pancreatic deficiency following hemolytic uremic syndromeJournal of Pediatrics.  149:139. 2006
    2006 Bronchiolitis with hyponatremiaClinical Pediatrics.  45:101-102. 2006
    2006 Prevalence of hypovitaminosis D in early infantile hypocalcemiaJournal of Pediatric Endocrinology and Metabolism.  19:1025-1031. 2006
    2006 Reversible subclinical hypothyroidism in the presence of adrenal insufficiencyEndocrine Practice.  12:572-575. 2006
    2005 Unusual case of neonatal diabetes mellitus due to congenital pancreas agenesisPediatric Diabetes.  6:239-243. 2005
    2005 Effect of insulin on plasma vascular endothelial growth factor in children with new-onset diabetesJournal of Clinical Endocrinology and Metabolism.  90:4920-4923. 2005
    2005 Index of suspicion.Pediatrics in Review.  26:68-74. 2005
    2005 Vaginal bleeding and galactorrhea in a child with ovarian steroid cell tumorEndocrine Practice.  11:346-349. 2005
    2004 Hyperreninemia and hypoaldosteronism in a child with short statureEndocrinologist.  14:313-316. 2004
    Amorphous carbon films in direct current magnetron sputtering from regenerative sooting dischargeVacuum.  86:193.

    Chapter

    Year Title Altmetric
    2013 Delayed puberty.  203-217. 2013

    Research Overview

  • Diabetes mellitus, Lipid metabolism, Disorders of calcium and vitamin D.
  • Principal Investigator On

  • Private Grant  awarded by AEGERION PHARMACEUTICALS, INC. 2019 - 2031
  • Private Grant  awarded by OPKO BIOLOGICS LTD 2017 - 2019
  • Private Grant  awarded by MERCK SHARP & DOHME CORP 2013 - 2018
  • Private Grant  awarded by MERCK SHARP & DOHME CORP 2013 - 2017
  • Private Grant  awarded by MACROGENICS 2010 - 2013
  • Private Grant  awarded by MACROGENICS 2009 - 2011
  • Investigator On

    Education And Training

  • Bronx-Lebanon Hospital, Internship
  • Bronx-Lebanon Hospital, Residency
  • University of Alabama at Birmingham, Residency
  • University of Alabama at Birmingham, Postdoctoral Fellowship
  • Doctorate in Pediatrics Residency Program, 1996
  • Full Name

  • Ambika Ashraf
  • Fax

  • 205-638-9821