Selected Publications

Academic Article

Year Title Altmetric
2022 Breast papillomas in the United States: single institution data on underrepresented minorities with a multi-institutional update on incidenceClinical Imaging.  82:21-28. 2022
2022 18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 InhibitionClinical Cancer Research.  28:327-337. 2022
2021 An open-label, pilot study of veliparib and lapatinib in patients with metastatic, triple-negative breast cancerBreast Cancer Research.  23. 2021
2021 Utility of 18F-fluciclovine PET/MRI for staging newly diagnosed high-risk prostate cancer and evaluating response to initial androgen deprivation therapy: A prospective single-arm pilot studyAmerican Journal of Roentgenology.  217:720-729. 2021
2021 Out with the Old and in with the New? Factors Involved in Migration of Older and Newer Generation Stereotactic Breast Biopsy Markers 2021
2021 Cost-effectiveness of offering cervical cancer screening with HPV self-sampling among african-American women in the mississippi deltaCancer Epidemiology, Biomarkers and Prevention.  30:1114-1121. 2021
2021 Social support and diabetes distress among adults with type 2 diabetes covered by Alabama MedicaidDiabetic Medicine.  38. 2021
2021 Portable Perfusion Phantom Offers Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Accurate Prostate Cancer Grade Stratification: A Pilot StudyAcademic Radiology.  28:405-413. 2021
2021 Exosomal‑miR‑10a derived from colorectal cancer cells suppresses migration of human lung fibroblasts, and expression of IL‑6, IL‑8 and IL‑1βMolecular Medicine Reports.  23:1-10. 2021
2021 Given a choice between self-sampling at home for HPV testing and standard of care screening at the clinic, what do African American women choose? Findings from a group randomized controlled trialPreventive Medicine.  142. 2021
2020 Less Toxic Chemotherapy in Locally Advanced Breast CancerSouthern Medical Journal.  113:559-563. 2020
2020 WSTF acetylation by MOF promotes WSTF activities and oncogenic functionsOncogene.  39:5056-5067. 2020
2020 TBCRC 002: A phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancerBreast Cancer Research.  22. 2020
2020 miR-639 Expression Is Silenced by DNMT3A-Mediated Hypermethylation and Functions as a Tumor Suppressor in Liver Cancer CellsMolecular Therapy.  28:587-598. 2020
2019 Medicaid Expansion and Hospitalization for Ambulatory Care-Sensitive Conditions among Nonelderly Adults with DiabetesJournal of Ambulatory Care Management.  42:312-320. 2019
2019 Lay navigation across the cancer continuum for older cancer survivors: Equally beneficial for Black and White survivors?Journal of Geriatric Oncology.  10:779-786. 2019
2019 Survival Outcomes of Very Small Drug-Eluting Beads Used in Chemoembolization of Unresectable Hepatocellular Carcinoma 2019
2019 JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activityOncogene.  38:980-997. 2019
2019 Accurate Therapeutic Response Assessment of Pancreatic Ductal Adenocarcinoma Using Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging with a Point-of-Care Perfusion Phantom: A Pilot StudyInvestigative Radiology.  54:16-22. 2019
2019 Infection of small-bore tunneled central venous cathetersAmerican Journal of Roentgenology.  213:458-463. 2019
2019 Lack of efficacy of high-titered immunoglobulin in patients with West Nile virus central nervous system diseaseEmerging Infectious Diseases.  25:2064-2073. 2019
2019 Urgent-Start Peritoneal Dialysis Catheter Placement: Comparative Study between Percutaneous Image-Guided versus Laparoscopic Techniques 2019
2018 An analysis of potential predictors of tunneled hemodialysis catheter infection or dysfunction 2018
2018 An Exploration of Multilevel Physical Activity Correlates among Low-Income African Americans in Alabama and MississippiFamily and Community Health.  41:197-204. 2018
2018 Diffusion-weighted MRI as a screening tool for hepatocellular carcinoma in cirrhotic livers: correlation with explant data—a pilot study 2018
2018 The anti-tumor effects of Mfn2 in breast cancer are dependent on promoter DNA methylation, the P21Ras motif and PKA phosphorylation siteOncology Letters.  15:8011-8018. 2018
2018 Assessment of the nutrition environment in rural counties in the Deep SouthJournal of Nutritional Science.  7. 2018
2017 Policy, system and environmental correlates of fruit and vegetable consumption in a low-income African American population in the southeastEthnicity and Disease.  27:355-362. 2017
2017 Weight loss and improved metabolic outcomes amongst rural African American women in the Deep South: six-month outcomes from a community-based randomized trialJournal of Internal Medicine.  282:102-113. 2017
2017 Resource use and medicare costs during lay navigation for geriatric patients with cancerJAMA Oncology.  3:817-825. 2017
2017 Implementation and Impact of Patient Lay Navigator-Led Advance Care Planning ConversationsJournal of Pain and Symptom Management.  53:682-692. 2017
2017 Interactome analysis reveals a novel role for RAD6 in the regulation of proteasome activity and localization in response to DNA damageMolecular and Cellular Biology.  37. 2017
2017 MiR-10a suppresses colorectal cancer metastasis by modulating the epithelial-To-mesenchymal transition and anoikisCell Death and Disease.  8. 2017
2017 MicroRNA-20a contributes to cisplatin-resistance and migration of OVCAR3 ovarian cancer cell lineOncology Letters.  14:1780-1786. 2017
2016 Phosphorylation of H2A.XTyr39 positively regulates DNA damage response and is linked to cancer progression 2016
2016 Mitofusin-2 is required for mouse oocyte meiotic maturationScientific Reports.  6. 2016
2016 KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathwayOncotarget.  7:53153-53164. 2016
2016 The patient care connect program: Transforming health care through lay navigationJournal of Oncology Practice.  12:e633-e640. 2016
2016 Inhibition of the JAK/STAT pathway protects against α-synuclein-induced neuroinflammation and dopaminergic neurodegeneration 2016
2016 Expression of the MHC class II pathway in triple-negative breast cancer tumor cells is associated with a good prognosis and infiltrating lymphocytesCancer Immunology Research.  4:390-399. 2016
2016 Guiding lay navigation in geriatric patients with cancer using a distress assessment tool 2016
2016 Prognostic factors in advanced breast cancer: Race and receptor status are significant after development of metastasis 2016
2016 Uterine angiosarcoma: A case report and literature review 2016
2016 Williams syndrome transcription factor is a target of pro-oncogenic Ser158 phosphorylation mediated by Ras-MAPK pathway in human breast cancerInternational Journal of Clinical and Experimental Pathology.  9:1668-1675. 2016
2015 Combined therapy against recurrent and intracranial invasion of sinonasal hemangiopericytoma: A case reportOncology Letters.  10:287-290. 2015
2015 Significance of circulating tumor cells in metastatic triple-negative breast cancer patients within a randomized, phase II trial: TBCRC 019Clinical Cancer Research.  21:2771-2779. 2015
2015 TBCRC 019: A phase II trial of nanoparticle albumin-bound paclitaxel with or without the anti-death receptor 5 monoclonal antibody tigatuzumab in patients with triple-negative breast cancerClinical Cancer Research.  21:2722-2729. 2015
2015 PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancersBreast Cancer Research and Treatment.  150:569-579. 2015
2015 SEMA6D expression and patient survival in breast invasive carcinomaInternational Journal of Breast Cancer.  2015. 2015
2014 Predicting response and survival in chemotherapy-treated triple-negative breast cancerBritish Journal of Cancer.  111:1532-1541. 2014
2014 Pazopanib combined with radiation: In vivo model of interactionCancer Biotherapy and Radiopharmaceuticals.  29:247-250. 2014
2014 West Nile virus neuroinvasive disease: Neurological manifestations and prospective longitudinal outcomesBMC Infectious Diseases.  14. 2014
2014 A community-based, culturally relevant intervention to promote healthy eating and physical activity among middle-aged African American women in rural Alabama: Findings from a group randomized controlled trialPreventive Medicine.  69:13-20. 2014
2014 Assessing environmental support for better health: Active living opportunity audits in rural communities in the southern United StatesPreventive Medicine.  66:28-33. 2014
2014 MDM2-MOF-H4K16ac axis contributes to tumorigenesis induced by Notch 2014
2014 Prognostic factors in patients with metastatic breast cancer at the time of diagnosis 2014
2014 Secretory breast carcinoma in a 12-year-old girl: A case reportOncology Letters.  8:1635-1637. 2014
2014 The Impact of Breast Irradiation and Concurrent Trastuzumab on the Development of Early Cardiac Events: a Dosimetric AnalysisAmerican Journal of Breast Cancer Research.  1:9-19. 2014
2013 Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomesNucleic Acids Research.  41. 2013
2013 Validation of the Risk Model: High-Risk Classification and Tumor Pattern of Invasion Predict Outcome for Patients with Low-Stage Oral Cavity Squamous Cell CarcinomaHead and Neck Pathology.  7:211-223. 2013
2013 Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus 2013
2013 A phase II, randomized, open label trial of preoperative letrozole versus letrozole (LET) in combination with bevacizumab (BEV) in post-menopausal women with newly diagnosed stage II/III breast cancerJournal of Clinical Oncology.  31:527-527. 2013
2013 An open label, randomized, phase II trial of nanoparticle albumin-bound paclitaxel (nab-PAC) with or without the anti-death receptor 5 monoclonal antibody tigatuzumab in patients with metastatic triple negative breast cancerJournal of Clinical Oncology.  31. 2013
2013 KM method in estimation of Tumor Doubling time in Animal experimentJournal of the American Statistical Association, Section on Nonparametric Statistics.  2013:3611-3615. 2013
2012 Human Papillomavirus in Non-Oropharyngeal Head and Neck Cancers: A Systematic Literature ReviewHead and Neck Pathology.  6:104-120. 2012
2012 Basal-like breast cancer stem cells are sensitive to anti-DR5 mediated cytotoxicityBreast Cancer Research and Treatment.  133:437-445. 2012
2012 Effect of anti-DR5 and chemotherapy on basal-like breast cancerBreast Cancer Research and Treatment.  133:417-426. 2012
2012 Hormone receptor expression and risk of recurrence in patients with high-risk endometrial carcinoma treated with chemotherapyJournal of Clinical Oncology.  30:e15502-e15502. 2012
2011 Identification of three immunologic correlates for HIV type 1 pathogenesis in YouthAIDS Research and Human Retroviruses.  27:639-646. 2011
2011 Long-term follow-up of dose-dense neoadjuvant chemotherapy in patients with stage II/III breast cancer.Journal of Clinical Oncology.  29:e11048. 2011
2011 Breast carcinomas with isolated bone metastases have different hormone receptor expression profiles than those with metastases to other sites or multiple organsAnnals of Diagnostic Pathology.  15:79-83. 2011
2011 Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells 2011
2011 Combined modality therapy with TRAIL or agonistic death receptor antibodiesCancer Biology and Therapy.  11:431-449. 2011
2011 Genomic imprinting in mammals: Its life cycle, molecular mechanisms and reprogrammingCell Research.  21:466-473. 2011
2011 Evaluation of the Effectiveness of Two Drugs Combination Therapy in Vitro Cytotoxicity StudyJournal of the American Statistical Association, Section on Statistical Consulting.  2011:5147-5152. 2011
2010 Targets and dynamics of promoter DNA methylation during early mouse developmentNature Genetics.  42:1093-1100. 2010
2010 Clotrimazole induces a late G1 cell cycle arrest and sensitizes glioblastoma cells to radiation in vitro 2010
2010 Pilot trial of preoperative (Neoadjuvant) letrozole in combination with bevacizumab in postmenopausal women with newly diagnosed estrogen receptor-or progesterone receptor-positive breast cancerClinical Breast Cancer.  10:275-280. 2010
2010 Nuclear grade and survival in invasive lobular carcinoma: A case series with long-term follow-up 2010
2010 High-dimensional ROC analysis can improve the correlation between histological grade and oncotype-Dx recurrence risk in breast cancerJournal of the American Statistical Association, Section of Statistical Consulting.  2010:1607-1612. 2010
2009 Genetic epidemiology of glioblastoma multiforme: Confirmatory and new findings from analyses of human leukocyte antigen alleles and motifsPLoS ONE.  4. 2009
2009 Clear and independent associations of several HLA-DRB1 alleles with diVerential antibody responses to hepatitis B vaccination in youthHuman Genetics.  126:685-696. 2009
2009 Racial disparities on glycemic control and lipid profiles in children with type 1 diabetesClinical Medicine Insights: Endocrinology and Diabetes.  2009:1-6. 2009
2008 FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemiaBlood.  112:179-187. 2008
2008 A guided approach for personalized information search and visualizationInterdisciplinary Journal of Information, Knowledge, and Management.  3:11-21. 2008
2007 CCL3L1 and CCL4L1: Variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infectionGenes and Immunity.  8:224-231. 2007
2007 Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipientsClinical Infectious Diseases.  44:245-249. 2007
2007 A Comparative Study of Diffuse Large B-Cell Lymphoma (DLBCL) between African Americans and Caucasians: Single-Center Experience at the University of Alabama at Birmingham (UAB).Blood.  110:4430-4430. 2007
2007 Bayesian Statistical Power in Randomized Small Clinical TrialProceedings American Statistical Association, General Statistical Method Section.  2007:1257-1259. 2007
2007 Challenges faced by minority children in obtaining dental careJournal of Health Care for the Poor and Underserved.  18:779-788. 2007
2007 FCRL2 expression is predictive of IgVH mutation status and clinical progression in chronic lymphocytic leukemiaBlood.  S110:150a-151a. 2007
2007 FCRL2 is a Novel Prognostic Marker in B Cell Chronic Lymphocytic Leukemia 2007
2007 Factors influencing lipid profiles in children with type 1 diabetes mellitus:294Journal of Investigative Medicine.  55:S296-S296. 2007
2006 Immune response in humans to a nasal boost with Streptococcus mutans antigens 2006
2006 Comparison of parent and student responses to asthma surveys: Students grades 1-4 and their parents from an urban public school settingJournal of School Health.  76:236-240. 2006
2006 Regulatory challenges: Lessons from recent West Nile virus trials in the United StatesContemporary Clinical Trials.  27:254-259. 2006
2006 Interleukin 18 and human immunodeficiency virus type I infection in adolescents and adultsClinical and Experimental Immunology.  144:117-124. 2006
2006 Clinical Trial Design to Study Rare Infection DiseasesProceedings American Statistical Association, General Statistical Method Section.  2006:1208-1211. 2006
2005 A randomized, open-label study to evaluate the safety and pharmacokinetics of human hepatitis C immune globulin (Civacir) in liver transplant recipients 2005
2005 Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiformeCancer Epidemiology, Biomarkers and Prevention.  14:2040-2044. 2005
2004 Parameter Estimation for a proposed Joint Distribution of Correlated Bernoulli TrialsProceedings of the American Statistical Association, Statistical Computing Section.  2004:2504-2510. 2004
2003 Restorative cost savings related to dental sealants in Alabama Medicaid childrenPediatric Dentistry.  25:572-576. 2003
2003 Intranasal Immunization with Streptococcus Mutans Antigens: Low dose differentiates responses to soluble versus liposomal antigens 2003
2002 Disparities in dental service utilization among Alabama Medicaid childrenCommunity Dentistry and Oral Epidemiology.  30:369-376. 2002
2002 Intranasal immunization with Streptococcus mutans antigens in humans with liposome as adjuvant.Journal of Dental Research.  81:A313-A313. 2002
2001 Utilization of dental sealants by Alabama Medicaid children: barriers in meeting the year 2010 objectives.Pediatric Dentistry.  23:401-406. 2001
2000 Advance directives in cardiac and pulmonary rehabilitation patients 2000
1998 Preclinical pharmacology of the natural product anticancer agent 10-hydroxycamptothecin, an inhibitor of topoisomerase ICancer Chemotherapy and Pharmacology.  41:257-267. 1998
1998 Intracellular nucleotides of (-)-2',3'-deoxy-3'-thiacytidine in peripheral blood mononuclear cells of a patient infected with human immunodeficiency virusAntimicrobial Agents and Chemotherapy.  42:2989-2995. 1998
1997 Antitumor activity and pharmacokinetics following oral administration of natural product DNA topoisomerase I inhibitors 10-hydroxycamptothecin and camptothecin in SCID mice bearing human breast cancer xenograftsInternational Journal of Oncology.  10:1147-1156. 1997
1996 Reversed-phase high-performance liquid chromatography method for the simultaneous quantitation of the lactone and carboxylate forms of the novel natural product anticancer agent 10-hydroxycamptothecin in biological fluids and tissuesJournal of chromatography. B, Biomedical applications.  686:257-265. 1996
1996 Indoor and outdoor air pollution in Tokyo and Beijing supercitiesAtmospheric Environment.  30:695-702. 1996
1993 Relationship between Trace Elements and Fluoride in Indoor Air in Endemic Fluorosis Areas 1993
1990 Research of Physical and Chemical Characteristics of Airborne Particles in Five Big Cities of ChinaAtmospheric Environment.  5:34-38. 1990
1990 Studies on Environmental Problems at the Areas of High Incidence of Lung Cancer at Xuanwei County, Yunnan Province 1990
1989 Distributions of Inorganic Anions in Different Size Airborne ParticlesAtmospheric Environment (Chinese).  4:19-23. 1989
1989 Spectrophotometer of Determination of Sulfur Dioxide with Morpholine AbsorbentAtmospheric Environment (Chinese).  4:32-36. 1989
1988 Latest development of Liquid Chromatography (A Review)Hygiene Research (Chinese).  3:145-148. 1988

Research Overview

  • -Clinical Trials Design, Conduct and Management
    -Bayesian Method in Clinical Trial Design and Data Analysis
    -Multivariate Analysis and Statistical Modeling
    -Statistical Methods in Genome-Wide Association (GWAS) Studies
  • Investigator On

  • 3/3 Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership  awarded by National Cancer Institute/NIH/DHHS
  • Accurate DCE-MRI Measurement of Glioblastoma using Point-of-care Portable Perfusion Phantom  awarded by National Cancer Institute/NIH/DHHS
  • Active - Biostatistics and Bioinformatics - Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS
  • Death Receptor-Mediated Apoptosis and Therapy Strategies in Ovarian Cancer  awarded by National Cancer Institute/NIH/DHHS
  • Deep South Network for Cancer Control  awarded by National Cancer Institute/NIH/DHHS
  • Developing Early Prognostic Imaging Biomarkers Of ADPKD Based On Dynamic Changes In Cyst Growth Rates  awarded by PKD Foundation for Research in Polycystic Kidney Disease
  • Disposable Perfusion Phantom for Accurate DCE-MRI Measurement of Pancreatic Cancer Therapy Response  awarded by National Cancer Institute/NIH/DHHS
  • Disposable Perfusion Phantom for Accurate DCE-MRI Measurement of Pancreatic Cancer Therapy Response  awarded by National Cancer Institute/NIH/DHHS
  • Elevated NF-kB Signaling in Breast Cancers of African American Women  awarded by H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE
  • Engineered HSV for the Treatment of Malignant Glioma  awarded by National Cancer Institute/NIH/DHHS
  • Engineered HSV for the Treatment of Malignant Glioma - Core A. Administrative Core  awarded by National Cancer Institute/NIH/DHHS
  • Exploiting TNBC Vulnerabilities Via Rationally Combined Therapies  awarded by American Association for Cancer Research
  • FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors  awarded by St. Baldrick's Foundation
  • Gulf States Collaborative Center for Health Policy Research (Gulf States CC)  awarded by BAYOU LA BATRE CLINIC
  • Molecular Predictors of Post-Mastectomy Breast Cancer Loco-Regional Recurrence  awarded by National Cancer Institute/NIH/DHHS
  • Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership: Biostatistics/Bioinformatics Shared Resource  awarded by National Cancer Institute/NIH/DHHS
  • Personalizing Immunotherapy in HER2+ Breast Cancer through Quantitative Imaging  awarded by National Cancer Institute/NIH/DHHS
  • Private Grant  awarded by PACKHEALTH
  • Promoting Weight-Loss in African American Cancer Survivors in the Deep South  awarded by National Cancer Institute/NIH/DHHS
  • Quantitative CT Biomarkers to Predict Metastatic RCC Response to Anti-Angiogenic Therapy  awarded by DOD - Department of Defense
  • Quantitative Imaging To Personalize Therapy in Her2 Breast Cancer  awarded by American Cancer Society, Inc.
  • SPORE in Breast Cancer  awarded by National Cancer Institute/NIH/DHHS
  • Self-Sampling for HPV Testing in African American Women - Mississippi Delta  awarded by American Cancer Society, Inc.
  • The Alabama Care Plan: Assessing the Impact of Regional Care Organizations on Diabetes Outcomes in a Sample of Alabama Medicaid Recipients  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB / UMN SPORE in Pancreatic Cancer  awarded by National Cancer Institute/NIH/DHHS
  • UAB / UMN SPORE in Pancreatic Cancer - Core C  awarded by National Cancer Institute/NIH/DHHS
  • Education And Training

  • Doctor of Philosophy in Biostatistics, University of Alabama at Birmingham 2003
  • Master of Science in Biostatistics, University of Alabama at Birmingham 2000
  • Master of Sciences or Mathematics in Biomedical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College 1988
  • Bachelor of Science or Mathematics in Chemistry, Nankai University 1983
  • Full Name

  • Yufeng Li
  • Fax

  • 205-934-4262