• Jarred Younger completed postdoctoral fellowships at Arizona State University and the Stanford University School of Medicine before taking an Assistant Professor position at Stanford.

    He has recently joined the UAB faculty in Psychology, with secondary appointments in Anesthesiology and Rheumatology. He is currently funded by the National Institutes of Health and the Department of Defense to study new techniques for diagnosing and treating neuroinflammation.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy.Brain Imaging and Behavior2019
    2018 Meta-analysis of cognitive performance in fibromyalgia.Journal of Clinical and Experimental Neuropsychology.  40:698-714. 2018
    2018 Daily Fluctuations of Progesterone and Testosterone Are Associated With Fibromyalgia Pain Severity.Journal of Pain.  19:410-417. 2018
    2017 Thermal Stimulation Changes Diffusivity of the Spinothalamic Tract.Spine.  43:E697-E702. 2017
    2017 Cytokine signature associated with disease severity in chronic fatigue syndrome patients.Proceedings of the National Academy of Sciences.  114:E7150-E7158. 2017
    2017 Reduced Pro-Inflammatory Cytokines after Eight Weeks of Low-Dose Naltrexone for Fibromyalgia.Biomedicines.  5. 2017
    2017 Brief Report: IL-1β Levels Are Associated With Chronic Multisite Pain in People Living With HIV.Journal of Acquired Immune Deficiency Syndromes.  75:e99-e103. 2017
    2016 Association of Leptin with Body Pain in Women.Journal of Women's Health.  25:752-760. 2016
    2016 Development of the Sensory Hypersensitivity Scale (SHS): a self-report tool for assessing sensitivity to sensory stimuli.Journal of Behavioral Medicine.  39:537-550. 2016
    2016 Identification and Treatment of New Inflammatory Triggers for Complex Regional Pain Syndrome: Small Intestinal Bacterial Overgrowth and Obstructive Sleep Apnea.A&A Case Reports.  6:272-276. 2016
    2015 One Month of Oral Morphine Decreases Gray Matter Volume in the Right Amygdala of Individuals with Low Back Pain: Confirmation of Previously Reported Magnetic Resonance Imaging Results.Pain Medicine.  17:1497-1504. 2015
    2015 Pain Duration and Resolution following Surgery: An Inception Cohort Study.Pain Medicine.  16:2386-2396. 2015
    2015 Evidence for abnormal cytokine expression in Gulf War Illness: A preliminary analysis of daily immune monitoring data.BMC Immunology.  16:57. 2015
    2015 Acute opioid withdrawal is associated with increased neural activity in reward-processing centers in healthy men: A functional magnetic resonance imaging study.Drug and Alcohol Dependence.  153:314-322. 2015
    2015 Being female is a risk factor for chronic pain. Are inflammatory processes to blame?Brain, Behavior, and Immunity.  46:33-34. 2015
    2015 Relationship of pain and ancestry in African American women.European Journal of Pain.  19:601-610. 2015
    2015 Acute opioid withdrawal is associated with increased neural activity in reward-processing centers in healthy men: A functional magnetic resonance imaging studyDrug and Alcohol Dependence.  153:314-322. 2015
    2015 Relationship of pain and ancestry in African American womenEuropean Journal of Pain2015
    2014 Erratum to: "A control systems engineering approach for adaptive behavioral interventions: illustration with a fibromyalgia intervention" [Translational Behavioral Medicine, Volume 4, Issue 3, pp 275-289].Translational Behavioral Medicine.  4:439. 2014
    2014 Optimized Treatment of Fibromyalgia Using System Identification and Hybrid Model Predictive Control.Control Engineering Practice.  33:161-173. 2014
    2014 A control systems engineering approach for adaptive behavioral interventions: illustration with a fibromyalgia intervention.Translational Behavioral Medicine.  4:275-289. 2014
    2014 Preoccupation in an early-romantic relationship predicts experimental pain relief.Pain Medicine.  15:947-953. 2014
    2014 Self-loathing aspects of depression reduce postoperative opioid cessation rate.Pain Medicine.  15:954-964. 2014
    2014 Multivariate classification of structural MRI data detects chronic low back pain.Cerebral Cortex.  24:1037-1044. 2014
    2014 The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain.Clinical Rheumatology.  33:451-459. 2014
    2014 Complex regional pain syndrome is associated with structural abnormalities in pain-related regions of the human brain.Journal of Pain.  15:197-203. 2014
    2013 Identification of Affine Linear Parameter Varying Models for Adaptive Interventions in Fibromyalgia Treatment.Proceedings of the American Control Conference.  2013:1976-1981. 2013
    2013 A pilot functional MRI study of the effects of prefrontal rTMS on pain perception.Pain Medicine.  14:999-1009. 2013
    2013 Perioperative interventions to reduce chronic postsurgical pain.Journal of Reconstructive Microsurgery.  29:213-222. 2013
    2013 Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology.Journal of Translational Medicine.  11:93. 2013
    2013 Pain in chronic medical illnessPain Research and Treatment.  2013. 2013
    2013 Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels.Arthritis and Rheumatism.  65:529-538. 2013
    2012 Development of the Stanford Expectations of Treatment Scale (SETS): a tool for measuring patient outcome expectancy in clinical trials.Clinical Trials.  9:767-776. 2012
    2012 A pilot cohort study of the determinants of longitudinal opioid use after surgery.Anesthesia and Analgesia.  115:694-702. 2012
    2011 Prescription opioid analgesics rapidly change the human brain.PAIN.  152:1803-1810. 2011
    2011 A Control Engineering Approach for Designing an Optimized Treatment Plan for Fibromyalgia.Proceedings of the American Control Conference.  2011:4798-4803. 2011
    2011 Towards a physiology-based measure of pain: patterns of human brain activity distinguish painful from non-painful thermal stimulation.PLoS ONE.  6:e24124. 2011
    2011 Visualization of painful experiences believed to trigger the activation of affective and emotional brain regions in subjects with low back pain.PLoS ONE.  6:e26681. 2011
    2010 Viewing pictures of a romantic partner reduces experimental pain: involvement of neural reward systems.PLoS ONE.  5:e13309. 2010
    2010 Chronic myofascial temporomandibular pain is associated with neural abnormalities in the trigeminal and limbic systems.PAIN.  149:222-228. 2010
    2010 Pain quality predicts lidocaine analgesia among patients with suspected neuropathic pain.Pain Medicine.  11:617-621. 2010
    2009 Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot study.Pain Medicine.  10:663-672. 2009
    2009 Pain outcomes: a brief review of instruments and techniques.Current Pain and Headache Reports.  13:39-43. 2009
    2009 Effects of naltrexone on pain sensitivity and mood in fibromyalgia: no evidence for endogenous opioid pathophysiology.PLoS ONE.  4:e5180. 2009
    2009 Randomized clinical trial of acupuncture for myofascial pain of the jaw muscles.Journal of Orofacial Pain.  23:353-359. 2009
    2008 Reduced cold pain tolerance in chronic pain patients following opioid detoxification.Pain Medicine.  9:1158-1163. 2008
    2008 Chronic stress and regulation of cellular markers of inflammation in rheumatoid arthritis: implications for fatigue.Brain, Behavior, and Immunity.  22:24-32. 2008
    2008 Personal mastery predicts pain, stress, fatigue, and blood pressure in adults with rheumatoid arthritis.Psychology and Health.  23:515-535. 2008
    2007 Hypnotizability and somatic complaints: a gender-specific phenomenon.International Journal of Clinical and Experimental Hypnosis.  55:1-13. 2007
    2006 Effects of naltrexone on repressive coping and disclosure of emotional material: a test of the opioid-peptide hypothesis of repression and hypertension.Psychosomatic Medicine.  68:734-741. 2006
    2006 Anatomy of a hypnotic response: Self-report estimates, actual behavior, and physiological response to the hypnotic suggestion for arm rigidity.International Journal of Clinical and Experimental Hypnosis.  54:186-205. 2006
    2006 Effects of naltrexone on repressive coping and disclosure of emotional material: A test of the opioid-peptide hypothesis of repression and hypertensionPsychosomatic Medicine.  68:734-741. 2006
    2006 The role of adult attachment style in forgiveness following an interpersonal offenseJournal of Counseling and Development.  84:493-502. 2006
    2005 The Harvard Group Scale of Hypnotic Susceptibility: accuracy of self-report and the memory for items.International Journal of Clinical and Experimental Hypnosis.  53:306-320. 2005
    2005 Spirituality predicts Health and cardiovascular responses to stress in young adult womenJournal of Religion and Health.  44:161-171. 2005
    2005 The unique effects of forgiveness on health: an exploration of pathways.Journal of Behavioral Medicine.  28:157-167. 2005
    2004 Dimensions of forgiveness: The views of laypersonsJournal of Social and Personal Relationships.  21:837-855. 2004
    2004 Perceived links between physical problems and stress may be clouded by dissociative processesJournal of Trauma and Dissociation.  5:121-127. 2004
    2004 The computer-assisted cognitive/imagery system for use in the management of pain.Pain Research and Management.  9:157-162. 2004
    2003 A change of heart: cardiovascular correlates of forgiveness in response to interpersonal conflict.Journal of Behavioral Medicine.  26:373-393. 2003
    2002 Theobiology: An analysis of spirituality, cardiovascular responses, stress, mood, and physical healthJournal of Religion and Health.  41:347-362. 2002
    2000 An alternative approach for achieving cardiovascular baseline: viewing an aquatic video.International Journal of Psychophysiology.  37:207-217. 2000
    2000 Forgiveness: Physiological and psychological correlatesPsychosomatic Medicine.  62:101-101. 2000
    2000 Physiological and psychological correlates of attachment style and family marital status in forgiveness recall interviewsPsychosomatic Medicine.  62:118-118. 2000
    Daily opioid analgesic use reduces blood insulin levels.Journal of Opioid Management.  14:165-170.


    Year Title Altmetric
    2012 Hypnosis and mind-body interactions 2012
    2010 Arthritis - Psychological.  261-264. 2010

    Research Overview

  • The Neuroinflammation, Pain and Fatigue Laboratory uses neuroimaging, pharmaceutical, and immunological techniques to understand and treat chronic diseases. We believe that low-level inflammation of the brain drives pain, fatigue, depression, and cognitive decline in millions of people. Low-level inflammation may also drive memory problems and fatigability as people age. We also investigate the impact that addictive drugs (such as opioid pain medications) have on the human brain. We use magnetic resonance imaging (MRI), pharmacologic MRI (phfMRI), diffusion tensor imaging (DTI), and magnetic resonance spectroscopy (MRS) neuroimaging techniques.

    Neuroinflammation, pain, anesthesiology, rheumatology
  • Education And Training

  • Doctor of Philosophy in Health Psychology, Maryville College
  • Full Name

  • Jarred Younger
  • Blazerid

  • younger