Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Targeted expression of cyclin D2 ameliorates late stage anthracycline cardiotoxicityCardiovascular Research.  115:960-965. 2019
2019 Y-27632 preconditioning enhances transplantation of human-induced pluripotent stem cell-derived cardiomyocytes in myocardial infarction miceCardiovascular Research.  115:343-356. 2019
2019 Convergences of Life Sciences and Engineering in Understanding and Treating Heart FailureCirculation Research.  124:161-169. 2019
2018 Spheroids of cardiomyocytes derived from human-induced pluripotent stem cells improve recovery from myocardial injury in miceAJP - Heart and Circulatory Physiology.  315:H327-H339. 2018
2018 VEGF nanoparticles repair the heart after myocardial infarctionAJP - Heart and Circulatory Physiology.  314:H278-H284. 2018
2018 CCND2 Overexpression Enhances the Regenerative Potency of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Remuscularization of Injured VentricleCirculation Research.  122:88-96. 2018
2018 Can we engineer a human cardiac patch for therapy?Circulation Research.  123:244-265. 2018
2018 Large cardiac muscle patches engineered from human induced-pluripotent stem cell-derived cardiac cells improve recovery from myocardial infarction in swineCirculation.  137:1712-1730. 2018
2018 Protein phosphatase 5 and the tumor suppressor p53 down-regulate each other’s activities in miceJournal of Biological Chemistry.  293:18218-18229. 2018
2018 Regenerative potential of neonatal porcine heartsCirculation.  138:2809-2816. 2018
2017 Pathologic Stimulus Determines Lineage Commitment of Cardiac C-kit+ CellsCirculation.  136:2359-2372. 2017
2017 Cardiomyocyte proliferation prevents failure in pressure overload but not volume overloadJournal of Clinical Investigation.  127:4285-4296. 2017
2017 Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue EngineeringJournal of the American College of Cardiology.  70:766-775. 2017
2017 Meeting Report for the 2017 National Institutes of Health National Heart, Lung, and Blood Institute Progenitor Cell Biology Consortium: Cardiovascular Bioengineering Workshop and SymposiumCirculation Research.  120:1709-1712. 2017
2017 Biomarkers for monitoring chemotherapy-induced cardiotoxicityCritical Reviews in Clinical Laboratory Sciences.  54:87-101. 2017
2017 Pluripotent stem cell derived cardiac cells for myocardial repairJournal of Visualized Experiments.  2017. 2017
2016 31 P NMR 2D mapping of creatine kinase forward flux rate in hearts with postinfarction left ventricular remodeling in response to cell therapyPLoS ONE.  11. 2016
2016 Critical roles of STAT3 in β-adrenergic functions in the heartCirculation.  133:48-61. 2016
2014 P53 inhibition exacerbates late-stage anthracycline cardiotoxicityCardiovascular Research.  103:81-89. 2014
2013 Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activityDevelopment.  140:1946-1957. 2013
2012 Triggered firing and atrial fibrillation in transgenic mice with selective atrial fibrosis induced by over expression of TGF-β1Circulation Journal.  76:1354-1362. 2012
2012 Granulocyte colony-stimulating factor treatment plus dipeptidylpeptidase-IV inhibition augments myocardial regeneration in mice expressing cyclin D2 in adult cardiomyocytesEuropean Heart Journal.  33:129-137. 2012
2011 Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathyHuman Molecular Genetics.  20:4582-4596. 2011
2011 Tbx20 transcription factor is a downstream mediator for bone morphogenetic protein-10 in regulating cardiac ventricular wall development and functionJournal of Biological Chemistry.  286:36820-36829. 2011
2011 FKBP12 is a critical regulator of the heart rhythm and the cardiac voltage-gated sodium current in miceCirculation Research.  108:1042-1052. 2011
2011 Response to letter regarding article, "differential Cardiac Remodeling in Preload Versus Afterload"Circulation.  123. 2011
2011 Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesisDevelopment.  138:303-315. 2011
2010 Differential cardiac remodeling in preload versus afterloadCirculation.  122:993-1003. 2010
2009 Cell-cycle-based strategies to drive myocardial repairPediatric Cardiology.  30:710-715. 2009
2009 Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expressionCirculation Research.  104:1209-1216. 2009
2009 Acute doxorubicin cardiotoxicity is associated with p53-induced inhibition of the mammalian target of rapamycin pathwayCirculation.  119:99-106. 2009
2009 Smad7 is required for the development and function of the heartJournal of Biological Chemistry.  284:292-300. 2009
2008 A mouse model for juvenile doxorubicin-induced cardiac dysfunctionPediatric Research.  64:488-494. 2008
2008 The CUL7 E3 Ubiquitin Ligase Targets Insulin Receptor Substrate 1 for Ubiquitin-Dependent DegradationMolecular Cell.  30:403-414. 2008
2008 Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mtor-mediated signaling and cardiac functionJournal of Biological Chemistry.  283:13842-13849. 2008
2007 Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc bindingBiochimica et Biophysica Acta (BBA) - Molecular Cell Research.  1773:358-366. 2007
2006 Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growthJournal of Biological Chemistry.  281:27481-27491. 2006
2000 Effects of L-THP on Ca2+ overload of cultured rat cardiomyocytes during hypoxia and reoxygenationJournal- Tongji Medical University.  20:294-296. 2000

Teaching Activities

Education And Training

  • Doctor of Philosophy in Cell / Cellular Biology and Histology, Indiana University System : Indiana University-Bloomington 2007
  • Doctor of Medicine, Hubei University of Medicine 1995
  • Doctor of Philosophy in Cardiovascular Disease Residency Program, Tongji University 1995
  • Full Name

  • Wuqiang Zhu