• CF researcher
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 MicroRNA-145 antagonism reverses TGF-b inhibition of F508del CFTR correction in airway EpitheliaAmerican Journal of Respiratory and Critical Care Medicine.  197:632-643. 2018
    2017 Airway microbiota across age and disease spectrum in cystic fibrosis.European Respiratory Journal.  50. 2017
    2017 Pulmonary complications post hematopoietic stem cell transplant in dyskeratosis congenita: Analysis of oxidative stress in lung fibroblastsBone Marrow Transplantation.  52:765-768. 2017
    2017 Effect of prenatal versus postnatal Vitamin D deficiency on pulmonary structure and function in miceAmerican Journal of Respiratory Cell and Molecular Biology.  56:383-392. 2017
    2016 Constrictive bronchiolitis in cystic fibrosis adolescents with refractory pulmonary declineAnnals of the American Thoracic Society.  13:2174-2183. 2016
    2016 Risk stratification model to detect early pulmonary disease in infants with cystic fibrosis diagnosed by newborn screeningPediatric Pulmonology.  51:1168-1176. 2016
    2016 Safety, pharmacokinetics, and pharmacodynamics of ivacaftor in patients aged 2-years with cystic fibrosis and a CFTR gating mutation (KIWI): An open-label, single-arm studyLancet Respiratory Medicine.  4:107-115. 2016
    2016 Alterations in blood leukocytes of G551D-bearing cystic fibrosis patients undergoing treatment with ivacaftorJournal of Cystic Fibrosis.  15:67-73. 2016
    2015 Adherence to airway clearance therapy in pediatric cystic fibrosis: Socioeconomic factors and respiratory outcomesPediatric Pulmonology.  50:1244-1252. 2015
    2015 Risk factors for acute kidney injury during aminoglycoside therapy in patients with cystic fibrosisPediatric Nephrology.  30:1879-1888. 2015
    2015 Acute Kidney Injury in Hospitalized Children With Cystic FibrosisJournal of Clinical Pediatric Nephrology.  2:5-5. 2015
    2014 TGF-beta downregulation of distinct chloride channels in cystic fibrosis-affected epitheliaPLoS ONE.  9. 2014
    2014 Development and maintenance of a biospecimen repository for clinical samples derived from pulmonary patientsClinical and Translational Science.  7:336-341. 2014
    2013 Erratum: Myofibroblast differentiation and enhanced Tgf-B signaling in cystic fibrosis lung disease (PLoS ONE (2013) 8 (8))PLoS ONE.  8. 2013
    2013 IP-10 Is a Potential Biomarker of Cystic Fibrosis Acute Pulmonary ExacerbationsPLoS ONE.  8. 2013
    2013 Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung DiseasePLoS ONE.  8. 2013
    2013 Crohn's disease with pulmonary manifestations in children: 2 case reports and review of the literatureJournal of Crohn's and Colitis.  7. 2013
    2011 Plasma TGF-β1 in pediatric cystic fibrosis: Potential biomarker of lung disease and response to therapyPediatric Pulmonology.  46:688-695. 2011
    2010 Inhaled versus systemic antibiotics and airway inflammation in children with cystic fibrosis and PseudomonasPediatric Pulmonology.  45:281-290. 2010
    2009 Transforming growth factor-β1 in bronchoalveolar lavage fluid from children with cystic fibrosisPediatric Pulmonology.  44:1057-1064. 2009
    2009 Experience of the school-aged child with tracheostomyInternational Journal of Pediatric Otorhinolaryngology.  73:975-980. 2009
    2009 Association of lower airway inflammation with physiologic findings in young children with cystic fibrosisPediatric Pulmonology.  44:503-511. 2009
    2006 Physiologic, bronchoscopic, and bronchoalveolar lavage fluid findings in young children with recurrent wheeze and coughPediatric Pulmonology.  41:709-719. 2006

    Research Overview

  • Cystic Fibrosis, Pediatric Lung Disease, TGF-beta signaling, Airway Remodeling, miRNA
  • Education And Training

  • Doctor of Medicine, Southwestern University 1999
  • Bachelor of Engineering in Materials Engineering, Rice University 1994
  • Johns Hopkins Hospital, Residency 2003
  • University of North Carolina Hospital, Postdoctoral Fellowship 2007
  • Full Name

  • William Harris