Positions

Overview

  • Dr. Holman trained in general and cardiothoracic surgery at Duke University under Dr. David Sabiston. During his residency, he performed research in the laboratory of Dr. James Cox. Dr. Holman was an instructor in cardiac surgery at UAB under Dr. Albert Pacifico and joined the faculty in 1988. Since that time, Dr. Holman has performed adult cardiothoracic operations at UAB and the Birmingham VA Medical Center. In addition, he worked in several areas of research including cardiac arrhythmias, ischemia-reperfusion injury and outcomes analysis for patients with heart assist devices. He has been awarded grants from the NIH, American Heart Association (including an Established Investigator award), VA, and industry. He has been a member of NIH and VA study sections and is currently the chairman of the American Heart Association (AHA) Surgery Study Section. When Dr. Holman began work at UAB, he started the ventricular assist device program. He has been the local principal investigator for numerous FDA Investigational New Device trials of ventricular assist devices. He has been a member or chairman of several data safety monitoring boards for new surgical devices. In 2007, Dr. Holman expanded his involvement at the Birmingham VA Medical Center to become the chief of surgical services. He has been involved in the expansion of existing services and the establishment of new services at the VA. Advances in the VA clinical programs culminated in promotion of the Birmingham VA Medical Center from a 1B to a 1A facility in 2014. Dr. Holman’s clinical interests include adult cardiac surgery (coronary artery bypass grafting and heart valve surgery) and surgery for heart failure (mechanical circulatory support devices). His research interests include topics in mechanical circulatory support and surgery for heart failure. He also has interests in surgical education and myocardial ischemia-reperfusion injury (heart attacks). Dr. Holman participated in the training of five NIH funded resident researchers and numerous clinical trainees in cardiothoracic surgery.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 Utility of nuclear stress imaging in predicting long-term outcomes one-year post CABG Surgery.Journal of Nuclear Cardiology2018
    2018 Evaluation of flow-modulation approaches in ventricular assist devices using an in-vitro endothelial cell culture model.The Journal of heart transplantation2018
    2018 Long-term clinical outcome and graft patency of radial artery and saphenous vein grafts in multiple arterial revascularizationJournal of Thoracic and Cardiovascular Surgery2018
    2017 INTERMACS Analysis of Stroke During Support With Continuous-Flow Left Ventricular Assist Devices: Risk Factors and Outcomes.JACC: Heart Failure.  5:703-711. 2017
    2016 Ventricular Assist Device in Acute Myocardial Infarction.Journal of the American College of Cardiology.  67:1871-1880. 2016
    2015 Benefits of a novel percutaneous ventricular assist device for right heart failure: The prospective RECOVER RIGHT study of the Impella RP device.The Journal of heart transplantation.  34:1549-1560. 2015
    2015 Changes over time in risk profiles of patients who undergo coronary artery bypass graft surgery: the Veterans Affairs Surgical Quality Improvement Program (VASQIP).JAMA Surgery.  150:308-315. 2015
    2015 Assessment and management of right ventricular failure in left ventricular assist device patients.Circulation Journal.  79:478-486. 2015
    2015 Octreotide in the management of recurrent gastrointestinal bleed in patients supported by continuous flow left ventricular assist devices.ASAIO Journal.  61:107-109. 2015
    2014 Completeness of coronary revascularization and survival: Impact of age and off-pump surgery.Journal of Thoracic and Cardiovascular Surgery.  148:1307-1315.e1. 2014
    2014 Perioperative outcomes after on- and off-pump coronary artery bypass grafting.Texas Heart Institute Journal.  41:144-151. 2014
    2013 Consequences of radial artery harvest: results of a prospective, randomized, multicenter trial.JAMA Surgery.  148:1020-1023. 2013
    2013 Trends over time in the relative use and associated mortality of on-pump and off-pump coronary artery bypass grafting in the Veterans Affairs system.JAMA Surgery.  148:1031-1036. 2013
    2013 Gastrointestinal bleeding in patients with ventricular assist devices is highest immediately after implantation.ASAIO Journal.  59:480-485. 2013
    2013 Use of retrospectively gated CT angiography to diagnose systolic LVAD inflow obstruction.ASAIO Journal.  59:542-546. 2013
    2013 Durability of left ventricular assist devices: Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) 2006 to 2011.Journal of Thoracic and Cardiovascular Surgery.  146:437-41.e1. 2013
    2013 Performing coronary artery bypass grafting off-pump may compromise long-term survival in a veteran population.Annals of Thoracic Surgery.  95:1952-1958. 2013
    2013 Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children.Circulation.  127:1702-1711. 2013
    2012 Continuous-flow devices and percutaneous site infections: clinical outcomes.The Journal of heart transplantation.  31:1151-1157. 2012
    2012 Perceptions and expectations of cardiothoracic residents and attending surgeons.Journal of Surgical Research.  177:e45-e52. 2012
    2012 Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS): what have we learned and what will we learn?Circulation.  126:1401-1406. 2012
    2012 Utility of nuclear stress imaging for detecting coronary artery bypass graft disease.BMC Cardiovascular Disorders.  12:62. 2012
    2012 Coronary artery bypass graft patency: residents versus attending surgeons.Annals of Thoracic Surgery.  94:482-488. 2012
    2012 Invited commentary.Annals of Thoracic Surgery.  94:467. 2012
    2012 Invited commentary.Annals of Thoracic Surgery.  94:264. 2012
    2012 Comparison of observed survival after ventricular assist device placement versus predicted survival without assist device using the Seattle heart failure model.ASAIO Journal.  58:93-97. 2012
    2012 Implantation of the HeartWare HVAD in a child after a recent thromboembolic stroke.Annals of Thoracic Surgery.  93:977-978. 2012
    2011 Costs and quality of life associated with radial artery and saphenous vein cardiac bypass surgery: results from a Veterans Affairs multisite trial.American Journal of Surgery.  202:532-535. 2011
    2011 Incremental value of live/real time three-dimensional transesophageal echocardiography over the two-dimensional technique in the assessment of sinus of valsalva aneurysm rupture.Echocardiography.  28:918-920. 2011
    2011 Surgical site infection prevention: time to move beyond the surgical care improvement program.Annals of Surgery.  254:494-499. 2011
    2011 Improvement in 2-year survival for ventricular assist device patients after implementation of an intensive surveillance protocol.The Journal of heart transplantation.  30:879-887. 2011
    2011 Use of a vascular plug to percutaneously occlude the outflow conduit of a dysfunctional left ventricular assist device.The Journal of heart transplantation.  30:733-734. 2011
    2011 Perceptions regarding cardiothoracic surgical training at Veterans Affairs hospitals.Journal of Thoracic and Cardiovascular Surgery.  141:1107-1113. 2011
    2011 DiscussionJournal of The American College of Surgeons.  212:467-469. 2011
    2011 Working formulation for the standardization of definitions of infections in patients using ventricular assist devices.The Journal of heart transplantation.  30:375-384. 2011
    2011 The generalizability of participants in Veterans Affairs Cooperative Studies Program 474, a multi-site randomized cardiac bypass surgery trial.Controlled Clinical Trials.  32:260-266. 2011
    2011 Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial.Journal of the American Medical Association.  305:167-174. 2011
    2011 Use of gated cardiac computed tomography angiography in the assessment of left ventricular assist device dysfunction.ASAIO Journal.  57:32-37. 2011
    2010 Highlights of the American Society for Artificial Internal Organs 2010 Conference.Artificial Organs.  34:795-797. 2010
    2010 Device related infections: are we making progress?Journal of Cardiac Surgery.  25:478-483. 2010
    2010 Infection after implantation of pulsatile mechanical circulatory support devices.Journal of Thoracic and Cardiovascular Surgery.  139:1632-1636.e2. 2010
    2010 Invited commentary.Annals of Thoracic Surgery.  89:1510. 2010
    2009 INTERMACS: interval analysis of registry data.Journal of The American College of Surgeons.  208:755-761. 2009
    2009 Clot lifespan model analysis of the effects of warfarin on thrombus growth and fibrinolysis: role of contact protein and tissue factor initiation.ASAIO Journal.  55:33-40. 2009
    2009 Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study.The Journal of heart transplantation.  28:44-50. 2009
    2009 Successful cardiac transplant after Berlin Heart bridge in a single ventricle heart: use of aortopulmonary shunt as a supplementary source of pulmonary blood flow.Journal of Thoracic and Cardiovascular Surgery.  137:e40-e42. 2009
    2008 Patency of internal jugular vein following repair after ECMO stabilization prior to Berlin Heart implantation: utility of repaired vein for subsequent cardiac catheterization and biopsy.Congenital Heart Disease.  3:411-414. 2008
    2008 Patient with hypofibrinolysis-mediated thromboembolism converted to a hypercoagulable/hyperfibrinolytic state via ventricular assist device placement.The Journal of heart transplantation.  27:1169-1171. 2008
    2008 Mechanical circulatory device thrombosis: a new paradigm linking hypercoagulation and hypofibrinolysis.ASAIO Journal.  54:351-358. 2008
    2008 The effects of a soluble polymer and bone wax on sternal healing in an animal model. Invited commentary.Annals of Thoracic Surgery.  85:1780. 2008
    2008 The effects of a soluble polymer and bone wax on sternal healing in an animal model. Invited commentary.Annals of Thoracic Surgery.  85:1780. 2008
    2008 Use of an intraperitoneal ventricular assist device with a polytetrafluoroethylene barrier decreases infections.The Journal of heart transplantation.  27:268-271. 2008
    2007 Microbiology of infection in mechanical circulatory support.Life support systems : the journal of the European Society for Artificial Organs.  30:764-770. 2007
    2007 Surgical management of a giant thoracic angiomyolipoma.Annals of Thoracic Surgery.  83:2201-2203. 2007
    2007 Sodium-hydrogen exchange inhibition and beta-blockade additively decrease infarct size.Annals of Thoracic Surgery.  83:1121-1127. 2007
    2007 Thrombelastographic method to quantify the contribution of factor XIII to coagulation kinetics.Blood Coagulation and Fibrinolysis.  18:145-150. 2007
    2007 Xenograft calcification in Reiter's syndrome.Journal of Heart Valve Disease.  16:159-161. 2007
    2007 Invited commentary.Annals of Thoracic Surgery.  83:509. 2007
    2007 Is early too early? Effect of shorter stays after bypass surgery.Annals of Thoracic Surgery.  83:100-107. 2007
    2006 Trends in postoperative length of stay after bypass surgery.American Heart Journal.  152:1194-1200. 2006
    2006 Mechanical circulatory support therapy as a bridge to transplant or recovery (new advances).Current Opinion in Cardiology.  21:120-126. 2006
    2006 Invited commentary.Annals of Thoracic Surgery.  81:710-711. 2006
    2006 Mitochondrial dysfunction in cardiac ischemia-reperfusion injury: ROS from complex I, without inhibition.BBA - Biochimica et Biophysica Acta.  1762:223-231. 2006
    2006 Native aortic valve insufficiency in patients with left ventricular assist devices.Annals of Thoracic Surgery.  81:e6-e8. 2006
    2005 Multiple treatment approach to limit cardiac ischemia-reperfusion injury.Annals of Thoracic Surgery.  80:1408-1416. 2005
    2005 Invited commentary.Annals of Thoracic Surgery.  80:948-949. 2005
    2005 Managing device infections: are we progressing or is infection an insurmountable obstacle?ASAIO Journal.  51:452-455. 2005
    2005 Automatic intraaortic balloon pump timing using an intrabeat dicrotic notch prediction algorithm: Invited CommentaryAnnals of Thoracic Surgery.  79:1022. 2005
    2005 Left ventricular assist devices as destination therapy: a new look at survival.Journal of Thoracic and Cardiovascular Surgery.  129:9-17. 2005
    2005 MagScrew total artificial heart in vivo performance above 200 beats per minute: Invited commentaryAnnals of Thoracic Surgery.  79:1383. 2005
    2004 Infection in permanent circulatory support: experience from the REMATCH trial.The Journal of heart transplantation.  23:1359-1365. 2004
    2004 Left ventricular assist device performance with long-term circulatory support: lessons from the REMATCH trial.Annals of Thoracic Surgery.  78:2123-2129. 2004
    2004 Clinical experience with the mini-extracorporeal circulation system: An evolution or a revolution? Invited commentaryAnnals of Thoracic Surgery.  77:2176. 2004
    2004 Does the use of routine duodenotomy (DUODX) affect rate of cure, development of liver metastases, or survival in patients with Zollinger-Ellison syndrome?Annals of Surgery.  239:617-625. 2004
    2004 Epicardial organization of human ventricular fibrillation.Heart Rhythm.  1:14-23. 2004
    2004 Outcomes of early extubation after bypass surgery in the elderly.Annals of Thoracic Surgery.  77:781-788. 2004
    2004 Alabama coronary artery bypass grafting project: results from phase II of a statewide quality improvement initiative.Annals of Surgery.  239:99-109. 2004
    2003 Intra-myocyte ion homeostasis during ischemia-reperfusion injury: effects of pharmacologic preconditioning and controlled reperfusion.Annals of Thoracic Surgery.  76:1252-1258. 2003
    2003 Hemodynamic evaluation of normally functioning Sulzer Carbomedics prosthetic valves.Ultrasound in Medicine and Biology.  29:649-657. 2003
    2003 Hemostatic analysis of a patient undergoing off-pump coronary artery bypass surgery with argatroban anticoagulation.Anesthesia and Analgesia.  96:956-958. 2003
    2003 Modulation of mitochondrial adenosine triphosphate-sensitive potassium channels and sodium-hydrogen exchange provide additive protection from severe ischemia-reperfusion injury.Journal of Thoracic and Cardiovascular Surgery.  125:863-871. 2003
    2003 Amiodarone in cardiothoracic surgery patients: what is a surgeon to do?Journal of Thoracic and Cardiovascular Surgery.  125:463-464. 2003
    2003 A flow visualization study of an anatomic coronary artery anastomosis model with an implant.Technology and Health Care.  11:21-39. 2003
    2003 Beneficial effect of autologous cell transplantation on infarcted heart function: comparison between bone marrow stromal cells and heart cells.Annals of Thoracic Surgery.  75:169-176. 2003
    2003 The hemodynamic effects of compliance, bulging, and curvature in a saphenous vein coronary artery bypass graft model.Technology and Health Care.  11:443-455. 2003
    2002 Mechanical circulatory support for myocarditis: how much recovery should occur before device removal?The Journal of heart transplantation.  21:1246-1249. 2002
    2002 The effects of acute and chronic amiodarone on activation patterns and defibrillation threshold during ventricular fibrillation in dogs.Journal of the American College of Cardiology.  40:375-383. 2002
    2002 Effect of a flow-streamlining implant at the distal anastomosis of a coronary artery bypass graft.Annals of Biomedical Engineering.  30:917-926. 2002
    2002 Treatment of end-stage heart disease with outpatient ventricular assist devices.Annals of Thoracic Surgery.  73:1489-1493. 2002
    2002 Ischemic preconditioning and Na+/H+ exchange inhibition improve reperfusion ion homeostasis.Annals of Thoracic Surgery.  73:569-574. 2002
    2001 Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation.Journal of Thoracic and Cardiovascular Surgery.  122:1186-1195. 2001
    2001 How to run an outpatient VAD program: overview.ASAIO Journal.  47:588-589. 2001
    2001 Albumin versus hydroxyethyl starch in cardiopulmonary surgery: A meta-analysis of postoperative bleedingbypass: Invited commentaryAnnals of Thoracic Surgery.  72:534. 2001
    2001 Mechanical circulatory support: expanding knowledge and experience in a challenging patient subset.Intensive Care Medicine.  27:1245-1246. 2001
    2001 Invited commentaryAnnals of Thoracic Surgery.  72:112-113. 2001
    2001 Cardiomyopathy in a carrier of Duchenne's muscular dystrophy.The Journal of heart transplantation.  20:781-784. 2001
    2001 Alabama coronary artery bypass grafting project: results of a statewide quality improvement initiative.Journal of the American Medical Association.  285:3003-3010. 2001
    2001 Infection with clinical ventricular assist devices: clinical therapy.ASAIO Journal.  47:195-196. 2001
    2001 A new method of monitoring recovery and weaning the Thoratec left ventricular assist device.Annals of Thoracic Surgery.  71:215-218. 2001
    2001 Cell volume and ionic transport systems after cold preservation of coronary endothelial cells: Invited commentaryAnnals of Thoracic Surgery.  71:1295. 2001
    2001 Discussion of economics of devicesAnnals of Thoracic Surgery.  71:S202-S203. 2001
    2000 Prophylactic value of preincision intra-aortic balloon pump: analysis of a statewide experience.Journal of Thoracic and Cardiovascular Surgery.  120:1112-1119. 2000
    2000 Right thoracotomy for mitral reoperation: analysis of technique and outcome.Annals of Thoracic Surgery.  70:1970-1973. 2000
    2000 Fungal infections in ventricular assist devices.ASAIO Journal.  46:S37-S40. 2000
    2000 Cost-benefit analysis of extended antifungal prophylaxis in ventricular assist devices.ASAIO Journal.  46:587-589. 2000
    2000 Pneumoperitoneum after concomitant resection of the right middle and lower lobes (bilobectomy).Annals of Thoracic Surgery.  70:942-946. 2000
    2000 Aortic dissection with intimal intussusception: diagnosis and management.Journal of Cardiovascular Surgery.  41:613-615. 2000
    2000 Controlled postcardioplegia reperfusion: mechanism for attenuation of reperfusion injury.Journal of Thoracic and Cardiovascular Surgery.  119:1093-1101. 2000
    2000 Novel methods to evaluate controlled reperfusion techniques in cardiac surgery.International journal of surgical investigation.  1:397-407. 2000
    1999 Outcome after myocardial revascularization and renal transplantation: a 25-year single-institution experience.Annals of Surgery.  230:232-241. 1999
    1998 Arrest duration influences postcardioplegia electrophysiologic recovery and reperfusion arrhythmiasAnnals of Thoracic Surgery.  65:1003-1008. 1998
    1998 A prospective algorithm for the management of air leaks after pulmonary resection.Annals of Thoracic Surgery.  66:1726-1731. 1998
    1998 Usefulness of Transesophageal Echocardiography in Diagnosing Valve Leakage of Left Ventricular Assist Device.Echocardiography.  15:703-708. 1998
    1998 Gene Polymorphisms for PAI-1 Are Associated with the Angiographic Extent of Coronary Artery Disease.Journal of Thrombosis and Thrombolysis.  5:143-150. 1998
    1998 Evaluation of complex mediastinal masses by magnetic resonance imaging.Journal of Cardiovascular Surgery.  39:117-119. 1998
    1997 Simultaneous use of an implanted defibrillator and ventricular assist device.Annals of Thoracic Surgery.  64:1156-1158. 1997
    1997 Replacement of an intracorporeal left ventricular assist device.Annals of Thoracic Surgery.  64:839-841. 1997
    1997 Ventricular assist devices as a bridge to cardiac transplantation. A prelude to destination therapy.Annals of Surgery.  225:695-704. 1997
    1997 Platypnea and orthodeoxia: shunting associated with an aortic aneurysm.Journal of Thoracic and Cardiovascular Surgery.  113:955-956. 1997
    1997 MEDOS HIA-VAD biventricular assist device for bridge to recovery in fulminant myocarditis: Invited commentaryAnnals of Thoracic Surgery.  63:1146. 1997
    1997 Preoperative and postoperative comparison of patients with univentricular and biventricular support with the thoratec ventricular assist device as a bridge to cardiac transplantation.Journal of Thoracic and Cardiovascular Surgery.  113:202-209. 1997
    1996 Coronary vascular regulation during postcardioplegia reperfusion.Journal of Thoracic and Cardiovascular Surgery.  112:1054-1063. 1996
    1996 Measurement of percent oxyhemoglobin by optical densitometry in perfluorocarbon supplemented blood.ASAIO Journal.  42:M769-M773. 1996
    1996 Resection of multiple pulmonary metastases from a recurrent intracranial meningioma.Annals of Thoracic Surgery.  61:1823-1824. 1996
    1996 Extensive pulmonary metastasis of an intracranial meningioma with repeated recurrence: radiographic and pathologic features.Southern Medical Journal.  89:313-318. 1996
    1996 Usefulness of Transesophageal Echocardiography in Diagnosing and Guiding Correct Placement of a Right Ventricular Assist Device Malpositioned in the Left Atrium.Echocardiography.  13:159-164. 1996
    1996 Infections during extended circulatory support: University of Alabama at Birmingham experience 1989 to 1994.Annals of Thoracic Surgery.  61:366-371. 1996
    1995 Tissue oxygenation with graded dissolved oxygen delivery during cardiopulmonary bypass.Journal of Thoracic and Cardiovascular Surgery.  110:774-785. 1995
    1995 Left atrial or ventricular cannulation beyond 30 days for a Thoratec ventricular assist device.ASAIO Journal.  41:M517-M522. 1995
    1995 Perfluorocarbons are effective oxygen carriers in cardiopulmonary bypass.ASAIO Journal.  41:M636-M641. 1995
    1995 Mechanisms of transplant right ventricular dysfunction.Annals of Surgery.  221:666-675. 1995
    1995 Circulatory support for myocardial infarction with ventricular arrhythmias.Annals of Thoracic Surgery.  59:1230-1231. 1995
    1995 Incremental Value of Three‐Dimensional Echocardiography Over Transesophageal Multiplane Two‐Dimensional Echocardiography in Qualitative and Quantitative Assessment of Cardiac Masses and DefectsEchocardiography.  12:619-628. 1995
    1995 Transesophageal Echocardiographic Detection of Sinus of Valsalva DissectionEchocardiography.  12:99-102. 1995
    1994 Cardiac amyloidoma with IgM-kappa gammopathy.Archives of Pathology and Laboratory Medicine.  118:1148-1150. 1994
    1994 Effect of hemoglobin concentration on oxyhemoglobin dissociation during hypothermic blood cardioplegic arrest.Journal of Thoracic and Cardiovascular Surgery.  108:664-671. 1994
    1994 Effect of postcardioplegia reperfusion rhythm on myocardial blood flow.Annals of Thoracic Surgery.  58:351-358. 1994
    1994 Influence of longer term left ventricular assist device support on valvular regurgitation.ASAIO Journal.  40:M454-M459. 1994
    1994 Perfluorocarbon oxygen transport. A comparative study of four oxygenator designs.ASAIO Journal.  40:M649-M653. 1994
    1994 Ventricular assist: experience with a pulsatile heterotopic device.Seminars in Thoracic and Cardiovascular Surgery.  6:147-153. 1994
    1994 Anatomic definition of a vulnerable extranodal site in AV node reentry.Annals of Thoracic Surgery.  57:1273-1280. 1994
    1994 Treatment of recurrent heart rejection with mycophenolate mofetil (RS-61443): initial clinical experience.The Journal of heart transplantation.  13:444-450. 1994
    1994 Use of current generation perfluorocarbon emulsions in cardiac surgery.Artificial Cells, Blood Substitutes and Biotechnology.  22:979-990. 1994
    1993 Duration of asystolic reperfusion and reperfusate electrolyte composition influence postcardioplegia ventricular fibrillation.Journal of Thoracic and Cardiovascular Surgery.  106:511-519. 1993
    1993 The ivory tower from outside and in: a survey of Minnesota surgeons.Surgery.  114:436-440. 1993
    1993 The monosialoganglioside, GM1, reduces neurologic injury associated with hypothermic circulatory arrest.Surgery.  114:324-332. 1993
    1993 Sinus of Valsalva aneurysms and application of surgical science to their repair.Annals of Thoracic Surgery.  55:545-550. 1993
    1993 External pulsatile circulatory support.Annals of Thoracic Surgery.  55:257-260. 1993
    1993 Use of expanded polytetrafluoroethylene pericardial substitute with ventricular assist devices.Annals of Thoracic Surgery.  55:181-183. 1993
    1992 Electrical instability during reperfusion.Annals of Thoracic Surgery.  54:1245-1246. 1992
    1992 Long-term results of coronary artery bypass grafting.Current Opinion in Cardiology.  7:990-996. 1992
    1992 Operative results after unsuccessful radiofrequency ablation for Wolff-Parkinson-White syndrome.American Journal of Cardiology.  70:1490-1491. 1992
    1992 Quantitation of mapping uncertainty in Wolff-Parkinson-White syndrome. Implications for anatomic characterization and surgical division of accessory atrioventricular connections.Journal of Thoracic and Cardiovascular Surgery.  104:1045-1052. 1992
    1992 Wolff-Parkinson-White syndrome. A quantitative morphometric analysis of surgical anatomy.Journal of Thoracic and Cardiovascular Surgery.  104:802-811. 1992
    1992 Successful mechanical circulatory support for noncoronary shockThe Journal of heart transplantation.  11:129-135. 1992
    1992 Variation in cryolesion penetration due to probe size and tissue thermal conductivity.Annals of Thoracic Surgery.  53:123-126. 1992
    1991 Case report: circulatory support for seventy days with resolution of acute heart failure.Journal of Thoracic and Cardiovascular Surgery.  102:932-934. 1991
    1991 Usefulness of transesophageal echocardiography in assessment of aortic dissection.Circulation.  84:1903-1914. 1991
    1991 Removal of massive right atrial thrombus guided by transesophageal echocardiography.Annals of Thoracic Surgery.  52:313-315. 1991
    1991 Intermediate septal accessory pathways: electrocardiographic characteristics, electrophysiologic observations and their surgical implications.Journal of the American College of Cardiology.  17:1570-1578. 1991
    1991 Agglutination of blood cardioplegia by cold-reacting autoantibodies.Annals of Thoracic Surgery.  51:833-835. 1991
    1990 Transesophageal echocardiographic evaluation of mechanical biventricular assist device.Echocardiography.  7:561-566. 1990
    1990 Combined use of transesophageal echocardiography and endocardial mapping to localize the site of origin of ectopic atrial tachycardia.American Journal of Cardiology.  65:1284-1286. 1990
    1990 Coronary artery bypass grafting with unanticipated fibrosing mediastinitis.Annals of Thoracic Surgery.  49:321-322. 1990
    1989 The Blalock-Taussig shunt: an analysis of trends and techniques in the fourth decade.Journal of Cardiac Surgery.  4:113-124. 1989
    1988 Cryosurgical ablation of atrioventricular nodal reentry: histologic localization of the proximal common pathway.Circulation.  77:1356-1362. 1988
    1987 Cryosurgical treatment of atrioventricular node reentrant tachycardia.Circulation.  76:1329-1336. 1987
    1986 Cardiac cryosurgery: regional myocardial blood flow of ventricular cryolesions.Journal of Surgical Research.  41:524-528. 1986
    1986 The effects of cardioplegic potassium concentration and myocardial temperature on electrical activity in the heart during elective cardioplegic arrest.Journal of Thoracic and Cardiovascular Surgery.  92:755-765. 1986
    1986 Cryosurgical modification of retrograde atrioventricular conduction. Implications for the surgical treatment of atrioventricular nodal reentry tachycardia.Journal of Thoracic and Cardiovascular Surgery.  91:826-834. 1986
    1986 Surgical treatment of H-type tracheoesophageal fistula diagnosed in an adult.Annals of Thoracic Surgery.  41:453-454. 1986
    1985 Surgical treatment of supraventricular tachyarrhythmias.Surgical Clinics of North America.  65:553-570. 1985
    1984 Alteration of antegrade atrioventricular conduction by cryoablation of peri-atrioventricular nodal tissue. Implications for the surgical treatment of atrioventricular nodal reentry tachycardia.Journal of Thoracic and Cardiovascular Surgery.  88:67-75. 1984
    1984 The electrophysiologic effects of discrete cryosurgery for the treatment of supraventricular tachycardia due to AV nodal reentry.Circulation Journal.  48:127-135. 1984
    1983 Ventricular cryosurgery: short-term effects on intramural electrophysiology.Annals of Thoracic Surgery.  35:386-393. 1983
    1983 Cardiac cryosurgery: effects of myocardial temperature on cryolesion size.Surgery.  93:268-272. 1983
    1983 Cryosurgery for cardiac arrhythmias: acute and chronic effects on coronary arteries.American Journal of Cardiology.  51:149-155. 1983
    1983 Quantitation of cardiac cryolesion size by regional tissue resistanceSurgical Forum -Chicago-.  VOL. 34:348-350. 1983
    1983 Supraventricular conduction abnormalities following cardiac operations. A complication of inadequate atrial preservation.Journal of Thoracic and Cardiovascular Surgery.  85:105-115. 1983
    1982 Elective prolongation of atrioventricular conduction by multiple discrete cryolesions: a new technique for the treatment of paroxysmal supraventricular tachycardia.Journal of Thoracic and Cardiovascular Surgery.  84:554-559. 1982
    1982 Encircling endocardial ventriculotomy for refractory ischemic ventricular tachycardia. I. Electrophysiological effects.Journal of Thoracic and Cardiovascular Surgery.  83:840-849. 1982
    1982 Encircling endocardial ventriculotomy for refractory ischemic ventricular tachycardia. II. Effects on regional myocardial blood flow.Journal of Thoracic and Cardiovascular Surgery.  83:850-856. 1982
    1982 Encircling endocardial ventriculotomy for refractory ischemic ventricular tachycardia. III. Effects on regional left ventricular function.Journal of Thoracic and Cardiovascular Surgery.  83:857-864. 1982
    1982 Effects of cardioplegic infusion rate and topical hypothermia on elective cardiac arrestAmerican Journal of Cardiology.  49:894. 1982

    Chapter

    Year Title Altmetric
    2012 Complications of mechanical circulatory support devices.  718-721. 2012
    2012 INTERMACS.  730-732. 2012

    Research Overview

  • adult cardiac surgery, surgery for heart failure, mechanical circulatory support and surgery for heart failure, surgical education
  • Principal Investigator On

  • Private Grant  awarded by HEARTWARE, INC. 2015 - 2017
  • Private Grant  awarded by ABIOMED, INC. 2013 - 2015
  • Private Grant  awarded by ACORN CARDIOVASCULAR, INC. 2008 - 2014
  • Private Grant  awarded by BERLIN HEART, INC. 2008 - 2013
  • Investigator On

  • Private Grant  awarded by SUNSHINE HEART, INC. 2009 - 2016
  • Private Grant  awarded by EVAHEART, INC. 2011 - 2016
  • Private Grant  awarded by SUNSHINE HEART, INC. 2013 - 2016
  • Private Grant  awarded by ABBOTT VASCULAR, INC. 2014 - 2015
  • Randomized Evaluation of VAD Intervention before Inotropic Therapy (REVIVE-IT) Pilot Trial  awarded by University of Michigan 2013 - 2015
  • Private Grant  awarded by VENTRACOR, INC. 2007 - 2012
  • Private Grant  awarded by VENTRACOR, INC. 2007 - 2012
  • Education And Training

  • Bachelor's Degree, Williams College
  • Doctor of Medicine, Cornell University
  • Full Name

  • William Holman
  • Blazerid

  • wholman