Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Lessons Learned During Three Decades of Operations of Two Prospective Bioresources.Biopreservation and Biobanking2018
2018 Optoacoustic imaging identifies ovarian cancer using a microenvironment targeted theranostic wormhole mesoporous silica nanoparticle.Biomaterials.  182:114-126. 2018
2018 Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.Cell Reports.  25:1304-1317.e5. 2018
2018 A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.Cell Systems.  7:422-437.e7. 2018
2018 Nitrocellulose tissue prints: an innovative approach to preparing high quality DNA and RNA from prostate biopsies without compromising the cores for pathology diagnosis.Translational andrology and urology.  7:S514-S518. 2018
2018 Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200cCancer Letters.  431:1-10. 2018
2018 A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression.Neoplasia : An International Journal for Oncology Research.  20:894-904. 2018
2018 Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 PatientsCancer Cell.  34:211-224.e6. 2018
2018 Comprehensive Characterization of Cancer Driver Genes and Mutations.Cell.  174:1034-1035. 2018
2018 Erratum: The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (Cell Reports (2018) 23(1) (313–326.e5) (S2211124718304364) (10.1016/j.celrep.2018.03.075))Cell Reports.  23:3698. 2018
2018 Translational control of the undifferentiated phenotype in ER‑positive breast tumor cells: Cytoplasmic localization of ERα and impact of IRES inhibition.Oncology Reports.  39:2482-2498. 2018
2018 Reply to "Phase II prospective randomized trial of weight loss prior to radical prostatectomy".Prostate Cancer and Prostatic Diseases.  21:293-294. 2018
2018 A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.Cancer Cell.  33:690-705.e9. 2018
2018 Genomic and Functional Approaches to Understanding Cancer Aneuploidy.Cancer Cell.  33:676-689.e3. 2018
2018 lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.Cancer Cell.  33:706-720.e9. 2018
2018 A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.Cell.  173:386-399.e12. 2018
2018 An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.Cell.  173:400-416.e11. 2018
2018 Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.Cell.  173:291-304.e6. 2018
2018 Comprehensive Characterization of Cancer Driver Genes and Mutations.Cell.  173:371-385.e18. 2018
2018 Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.Cell.  173:338-354.e15. 2018
2018 Oncogenic Signaling Pathways in The Cancer Genome Atlas.Cell.  173:321-337.e10. 2018
2018 Pathogenic Germline Variants in 10,389 Adult Cancers.Cell.  173:355-370.e14. 2018
2018 Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.Cell.  173:305-320.e10. 2018
2018 Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.Cell Reports.  23:227-238.e3. 2018
2018 Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.Cell Reports.  23:239-254.e6. 2018
2018 Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.Cell Reports.  23:194-212.e6. 2018
2018 Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.Cell Reports.  23:213-226.e3. 2018
2018 Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.Cell Reports.  23:172-180.e3. 2018
2018 Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers.Cell Reports.  23:255-269.e4. 2018
2018 Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context.Cell Reports.  23:297-312.e12. 2018
2018 Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types.Cell Reports.  23:282-296.e4. 2018
2018 Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.Cell Reports.  23:181-193.e7. 2018
2018 Systematic Analysis of Splice-Site-Creating Mutations in Cancer.Cell Reports.  23:270-281.e3. 2018
2018 The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.Cell Reports.  23:313-326.e5. 2018
2018 Shifting sands: the complexities and uncertainties of the evolving US regulatory, policy, and scientific landscape for biospecimen researchDiagnostic Histopathology.  24:136-148. 2018
2018 Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.Cell Systems.  6:282-300.e2. 2018
2018 Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines.Cell Systems.  6:271-281.e7. 2018
2018 Standard PREanalytical Code Version 3.0Biopreservation and Biobanking.  16:9-12. 2018
2018 Factors that drive the increasing use of FFPE tissue in basic and translational cancer research.Stain technology.  93:373-386. 2018
2018 The Immune Landscape of Cancer.Immunity.  48:812-830.e14. 2018
2017 Presurgical weight loss affects tumour traits and circulating biomarkers in men with prostate cancer.British Journal of Cancer.  117:1303-1313. 2017
2017 Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling.Oncotarget.  8:69264-69280. 2017
2017 Epigenetic risk score improves prostate cancer risk assessment.Prostate.  77:1259-1264. 2017
2017 Genomic regulation of invasion by STAT3 in triple negative breast cancer.Oncotarget.  8:8226-8238. 2017
2017 Erratum to: Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer.BMC Cancer.  17:71. 2017
2017 Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development.Frontiers in Oncology.  7:158. 2017
2016 Effects of Cold Ischemia on Gene Expression: A Review and Commentary.Biopreservation and Biobanking.  14:548-558. 2016
2016 Noninvasive Imaging of Colitis Using Multispectral Optoacoustic Tomography.Journal of Nuclear Medicine.  58:1009-1012. 2016
2016 The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer.Oncotarget.  7:73739-73753. 2016
2016 Construction and Validation of a Multi-Institutional Tissue Microarray of Invasive Ductal Carcinoma From Racially and Ethnically Diverse Populations.Cancer Control : Journal of the Moffitt Cancer Center.  23:383-389. 2016
2016 IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells.Tumor Biology.  37:13247-13264. 2016
2016 Occult Metastases in Pelvic Lymphadenectomy Specimens From Patients With Urothelial Carcinoma of the Bladder.Urology.  94:161-166. 2016
2016 Current and Emerging Clinical Applications of Multispectral Optoacoustic Tomography (MSOT) in Oncology.Clinical Cancer Research.  22:3432-3439. 2016
2016 Acidic pH-targeted chitosan capped mesoporous silica coated gold nanorods facilitate detection of pancreatic tumors via multispectral optoacoustic tomography.ACS Biomaterials Science and Engineering.  2:1108-1120. 2016
2016 A standard tissue as a control for histochemical and immunohistochemical staining.Stain technology.  91:309-326. 2016
2016 The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.Cancer Research.  76:3978-3988. 2016
2016 A Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines.BMC Complementary and Alternative Medicine.  16:151. 2016
2016 RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4.Molecular Oncology.  10:1169-1182. 2016
2016 Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes.Cancer Immunology Research.  4:390-399. 2016
2016 Preservation of Biospecimens at Ambient Temperature: Special Focus on Nucleic Acids and Opportunities for the Biobanking Community.Biopreservation and Biobanking.  14:89-98. 2016
2016 SPARC-Independent Delivery of Nab-Paclitaxel without Depleting Tumor Stroma in Patient-Derived Pancreatic Cancer Xenografts.Molecular Cancer Therapeutics.  15:680-688. 2016
2016 Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy.AJP - Lung Cellular and Molecular Physiology.  310:L928-L939. 2016
2016 Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer.BMC Cancer.  16:61. 2016
2016 Surveying the serologic proteome in a tissue-specific kras(G12D) knockin mouse model of pancreatic cancer.Proteomics.  16:516-531. 2016
2016 Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974.Laboratory Investigation.  96:249-259. 2016
2016 Exploring effects of presurgical weight loss among women with stage 0-II breast cancer: protocol for a randomised controlled feasibility trial.BMJ Open.  6:e012320. 2016
2016 Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository.Methods in Molecular Biology.  1381:1-38. 2016
2016 The RANK Pathway in Advanced Breast Cancer: Does Src Play a Role?Applied Immunohistochemistry and Molecular Morphology.  24:42-50. 2016
2015 Missed Opportunities and Lost Lives: Consequences of Some Proposed Changes to Regulations on Research with Human Tissues--Letter.Clinical Cancer Research.  21:5404-5405. 2015
2015 Tumor specific liposomes improve detection of pancreatic adenocarcinoma in vivo using optoacoustic tomography.Journal of Nanobiotechnology.  13:90. 2015
2015 Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-Low Insertion Peptide Probes In Vivo.Clinical Cancer Research.  21:4576-4585. 2015
2015 TBCRC 019: A Phase II Trial of Nanoparticle Albumin-Bound Paclitaxel with or without the Anti-Death Receptor 5 Monoclonal Antibody Tigatuzumab in Patients with Triple-Negative Breast Cancer.Clinical Cancer Research.  21:2722-2729. 2015
2015 Quality management of biorepositories.Biopreservation and Biobanking.  13:183-194. 2015
2015 The protective effect of p16(INK4a) in oral cavity carcinomas: p16(Ink4A) dampens tumor invasion-integrated analysis of expression and kinomics pathways.Modern Pathology.  28:631-653. 2015
2015 PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers.Breast Cancer Research and Treatment.  150:569-579. 2015
2015 Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity.Oncogene.  34:1499-1509. 2015
2015 S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase.Scientific Reports.  5:8453. 2015
2015 Clinical Implications of Rabphillin-3A-Like Gene Alterations in Breast Cancer.PLoS ONE.  10:e0129216. 2015
2015 High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes.PLoS ONE.  10:e0139267. 2015
2015 Small molecule inhibitors of IRES-mediated translation.Cancer Biology and Therapy.  16:1471-1485. 2015
2014 An autoregulatory mechanism governing mucociliary transport is sensitive to mucus load.American Journal of Respiratory Cell and Molecular Biology.  51:485-493. 2014
2014 The effects of frozen tissue storage conditions on the integrity of RNA and protein.Stain technology.  89:518-528. 2014
2014 A functional anatomic defect of the cystic fibrosis airway.American Journal of Respiratory and Critical Care Medicine.  190:421-432. 2014
2014 Pazopanib combined with radiation: in vivo model of interaction.Cancer Biotherapy and Radiopharmaceuticals.  29:247-250. 2014
2014 IL-23 promotes TCR-mediated negative selection of thymocytes through the upregulation of IL-23 receptor and RORγt.Nature Communications.  5:4259. 2014
2014 Recurrent read-through fusion transcripts in breast cancer.Breast Cancer Research and Treatment.  146:287-297. 2014
2014 Erythropoietin upregulation in pulmonary arterial hypertension.Pulmonary Circulation.  4:269-279. 2014
2014 Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-β/SMAD signaling.Oncogene.  33:2620-2628. 2014
2014 Development of adrenal cortical zonation and expression of key elements of adrenal androgen production in the chimpanzee (Pan troglodytes) from birth to adulthood.Molecular and Cellular Endocrinology.  387:35-43. 2014
2014 Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model.British Journal of Cancer.  110:2000-2010. 2014
2014 Effect of niclosamide on basal-like breast cancers.Molecular Cancer Therapeutics.  13:800-811. 2014
2014 NSAIDs inhibit tumorigenesis, but how?Clinical Cancer Research.  20:1104-1113. 2014
2014 A framework for biobank sustainability.Biopreservation and Biobanking.  12:60-68. 2014
2014 L-Methionine inhibits growth of human pancreatic cancer cells.Anti-Cancer Drugs.  25:200-203. 2014
2014 A histological evaluation and in vivo assessment of intratumoral near infrared photothermal nanotherapy-induced tumor regression.International Journal of Nanomedicine.  9:5093-5102. 2014
2014 Anterior gradient protein-2 is a regulator of cellular adhesion in prostate cancer.PLoS ONE.  9:e89940. 2014
2014 Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions.American Journal of Pathology.  184:28-41. 2014
2014 Prediagnostic serum biomarkers as early detection tools for pancreatic cancer in a large prospective cohort study.PLoS ONE.  9:e94928. 2014
2013 Retargeting of gene expression using endothelium specific hexon modified adenoviral vector.Virology.  447:312-325. 2013
2013 It is primarily the control of transcription and post-transcriptional processing that are critical to the development and progression of sporadic neoplasias.Stain technology.  88:361-364. 2013
2013 Post-transcriptional processing of genetic information and its relation to cancer.Stain technology.  88:365-372. 2013
2013 Syndecan-1 overexpression is associated with nonluminal subtypes and poor prognosis in advanced breast cancer.American Journal of Clinical Pathology.  140:468-474. 2013
2013 Lung resistance-related protein (LRP) expression in malignant ascitic cells as a prognostic marker for advanced ovarian serous carcinoma.Annals of Surgical Oncology.  20:3059-3065. 2013
2013 Significant variation of immunohistochemical marker expression in paired primary and metastatic clear cell renal cell carcinomas.American Journal of Clinical Pathology.  140:410-418. 2013
2013 Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling.Molecular Cancer Therapeutics.  12:1848-1859. 2013
2013 Use of human specimens in research: the evolving United States regulatory, policy, and scientific landscape.Diagnostic Histopathology.  19:322-330. 2013
2013 An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.Journal of Biological Chemistry.  288:21197-21207. 2013
2013 The prognostic value of microRNAs varies with patient race/ethnicity and stage of colorectal cancer.Clinical Cancer Research.  19:3955-3965. 2013
2013 Frequencies of mtDNA mutations in primary tissues of colorectal adenopolyps.Frontiers in bioscience (Elite edition).  5:809-813. 2013
2013 Mouse model findings and the future of human tissue in disease research.Biopreservation and Biobanking.  11:135-136. 2013
2013 A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy.Molecular Cancer Therapeutics.  12:663-674. 2013
2013 Preservation of immunorecognition by transferring cells from 10% neutral buffered formalin to 70% ethanol.Stain technology.  88:170-180. 2013
2013 Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells.Journal of Immunology.  190:3579-3589. 2013
2013 Exosomes are endogenous nanoparticles that can deliver biological information between cells.Advanced Drug Delivery Reviews.  65:342-347. 2013
2013 Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis.American Journal of Pathology.  182:646-667. 2013
2013 Return of research results from genomic biobanks: a call for data.Genetics in Medicine.  15:159-160. 2013
2013 Return of research results from genomic biobanks: cost matters.Genetics in Medicine.  15:103-105. 2013
2013 An extensive targeted proteomic analysis of disease-related protein biomarkers in urine from healthy donors.PLoS ONE.  8:e63368. 2013
2013 Anti-inflammatory mechanisms of apolipoprotein A-I mimetic peptide in acute respiratory distress syndrome secondary to sepsis.PLoS ONE.  8:e64486. 2013
2013 COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs.Frontiers in Oncology.  3:181. 2013
2013 Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography.PLoS ONE.  8:e54473. 2013
2013 Selective COX-2 inhibitor (celecoxib) decreases cellular growth in prostate cancer cell lines independent of p53.Stain technology.  88:38-46. 2013
2013 The effect of antigen retrieval on cells fixed in 10% neutral buffered formalin followed by transfer to 70% ethanol.PLoS ONE.  8:e82405. 2013
2012 CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions.Journal of Biological Chemistry.  287:39115-39124. 2012
2012 Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: a multicenter study.American Journal of Gastroenterology.  107:1730-1739. 2012
2012 Nuclear Kaiso indicates aggressive prostate cancers and promotes migration and invasiveness of prostate cancer cells.American Journal of Pathology.  181:1836-1846. 2012
2012 Validation of a robust proteomic analysis carried out on formalin-fixed paraffin-embedded tissues of the pancreas obtained from mouse and human.Proteomics.  12:3393-3402. 2012
2012 A Critical Need for Increased Understanding of the Use of Human Tissues in Biomedical Research.Journal of Cancer Science and Therapy.  4:16-17. 2012
2012 Modern age pathology of pulmonary arterial hypertension.American Journal of Respiratory and Critical Care Medicine.  186:261-272. 2012
2012 A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.Cancer Prevention Research.  5:822-833. 2012
2012 Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance.Carcinogenesis.  33:1149-1157. 2012
2012 Differential expression of breast cancer-associated genes between stage- and age-matched tumor specimens from African- and Caucasian-American Women diagnosed with breast cancer.BMC Research Notes.  5:248. 2012
2012 (18)F-FDG PET/CT imaging detects therapy efficacy of anti-EMMPRIN antibody and gemcitabine in orthotopic pancreatic tumor xenografts.Clinical Positron Imaging.  14:237-244. 2012
2012 Exosomes and immune surveillance of neoplastic lesions: a review.Stain technology.  87:161-168. 2012
2012 Practical implementation issues and challenges for biobanks in the return of individual research results.Genetics in Medicine.  14:478-483. 2012
2012 Clinical and biological significance of KISS1 expression in prostate cancer.American Journal of Pathology.  180:1170-1178. 2012
2012 Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73.Cancer Cell.  21:196-211. 2012
2012 Predictors of long-term outcome from intraperitoneal radioimmunotherapy for ovarian cancer.Cancer Biotherapy and Radiopharmaceuticals.  27:36-40. 2012
2012 A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease.PLoS ONE.  7:e39809. 2012
2012 BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9.American Journal of Cancer Research.  2:540-548. 2012
2012 Corrigendum: Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brainMolecular Therapy.  20:239. 2012
2012 Tumor cell cross talk with tumor-associated leukocytes leads to induction of tumor exosomal fibronectin and promotes tumor progression.American Journal of Pathology.  180:390-398. 2012
2012 miRNAs are stable in colorectal cancer archival tissue blocks.Frontiers in bioscience (Elite edition).  4:1937-1940. 2012
2011 MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells.Carcinogenesis.  32:1832-1839. 2011
2011 Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins.Journal of Cellular Physiology.  226:3355-3367. 2011
2011 What are the most oppressing legal and ethical issues facing biorepositories and what are some strategies to address themBiopreservation and Biobanking.  9:317-319. 2011
2011 Extracelluar matrix metalloproteinase as a novel target for pancreatic cancer therapy.Anti-Cancer Drugs.  22:864-874. 2011
2011 The human face of biobank networks for translational researchBiopreservation and Biobanking.  9:279-285. 2011
2011 miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT.Oncogene.  30:3440-3453. 2011
2011 Expression and histopathological correlation of CCR9 and CCL25 in ovarian cancer.International Journal of Oncology.  39:373-381. 2011
2011 Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial-mesenchymal transition: role of TGFβ signaling pathway.Molecular Carcinogenesis.  50:516-527. 2011
2011 Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells.International Journal of Oncology.  39:111-119. 2011
2011 Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice.Arthritis and Rheumatism.  63:2038-2048. 2011
2011 Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging.Molecular Imaging.  10:153-167. 2011
2011 Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer.Journal of Hematology & Oncology.  4:25. 2011
2011 Plant homologue constitutive photomorphogenesis 9 (COP9) signalosome subunit CSN5 regulates innate immune responses in macrophages.Blood.  117:4796-4804. 2011
2011 CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion.World Journal of Surgical Oncology.  9:46. 2011
2011 CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion.International Journal of Oncology.  38:1279-1285. 2011
2011 LL-37 as a therapeutic target for late stage prostate cancer.Prostate.  71:659-670. 2011
2011 PCCR: Pancreatic Cancer Collaborative Registry.Cancer Informatics.  10:83-91. 2011
2011 Self-calibrated warping for mass spectra alignment.Cancer Informatics.  10:65-82. 2011
2011 Exosomes and cancer: a newly described pathway of immune suppression.Clinical Cancer Research.  17:959-964. 2011
2011 L-methionine-induced alterations in molecular signatures in MCF-7 and LNCaP cancer cells.Journal of Cancer Research and Clinical Oncology.  137:441-453. 2011
2011 Tumor exosome-mediated MDSC activation.American Journal of Pathology.  178:1403-1404. 2011
2011 Serum biomarker panels for the detection of pancreatic cancer.Clinical Cancer Research.  17:805-816. 2011
2011 DCE-MRI detects early vascular response in breast tumor xenografts following anti-DR5 therapy.Clinical Positron Imaging.  13:94-103. 2011
2011 A migration signature and plasma biomarker panel for pancreatic adenocarcinoma.Cancer Prevention Research.  4:137-149. 2011
2011 Erratum: Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples (Journal of Biomedical Optics (2010) 15 (067005))Journal of Biomedical Optics.  16. 2011
2011 The national lung screening trial: Overview and study designRadiology.  258:243-253. 2011
2011 Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brainMolecular Therapy.  19:1769-1779. 2011
2010 Bax expression is a candidate prognostic and predictive marker of colorectal cancer.Journal of Gastrointestinal Oncology.  1:76-89. 2010
2010 KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model.Clinical and Experimental Metastasis.  27:591-600. 2010
2010 A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases.Clinical Cancer Research.  16:5277-5287. 2010
2010 CCR9 mediates PI3K/AKT-dependent antiapoptotic signals in prostate cancer cells and inhibition of CCR9-CCL25 interaction enhances the cytotoxic effects of etoposide.International Journal of Cancer.  127:2020-2030. 2010
2010 Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples.Journal of Biomedical Optics.  15:067005. 2010
2010 Standards for immunohistochemical imaging: a protein reference device for biomarker quantitation.Journal of Histochemistry and Cytochemistry.  58:1005-1014. 2010
2010 Analysis of mtDNA sequence variants in colorectal adenomatous polyps.Diagnostic Pathology.  5:66. 2010
2010 A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes.Molecular Therapy.  18:1606-1614. 2010
2010 Mandatory fortification with folic acid in the United States appears to have adverse effects on histone methylation in women with pre-cancer but not in women free of pre-cancer.International Journal of Women's Health.  1:131-137. 2010
2010 Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer.Breast Cancer Research and Treatment.  123:59-71. 2010
2010 Prognostic value of mucin 4 expression in colorectal adenocarcinomas.Cancer.  116:3577-3586. 2010
2010 CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion.World Journal of Surgical Oncology.  8:62. 2010
2010 CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion.Journal of Ovarian Research.  3:15. 2010
2010 The deployment of a tissue request tracking system for the CHTN: a case study in managing change in informatics for biobanking operations.BMC Medical Informatics and Decision Making.  10:32. 2010
2010 Comparison of the predictive qualities of three prognostic models of colorectal cancer.Frontiers in bioscience (Elite edition).  2:849-856. 2010
2010 Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.Experimental and Molecular Pathology.  88:341-352. 2010
2010 Suppression by L-methionine of cell cycle progression in LNCaP and MCF-7 cells but not benign cells.Anticancer Research.  30:1881-1885. 2010
2010 NSAIDs: Old Drugs Reveal New Anticancer Targets.Pharmaceuticals.  3:1652-1667. 2010
2010 Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells.American Journal of Pathology.  176:2490-2499. 2010
2010 Biomarkers and the genetics of early neoplastic lesions.Cancer Biomarkers.  9:41-64. 2010
2010 Development and progression of colorectal neoplasia.Cancer Biomarkers.  9:235-265. 2010
2010 Issues in collecting, processing and storing human tissues and associated information to support biomedical research.Cancer Biomarkers.  9:531-549. 2010
2010 Organizational issues in providing high-quality human tissues and clinical information for the support of biomedical research.Methods in Molecular Biology.  576:1-30. 2010
2010 TLR2-mediated expansion of MDSCs is dependent on the source of tumor exosomesAmerican Journal of Pathology.  177:1606-1610. 2010
2010 The biology of incipient, pre-invasive or intraepithelial neoplasia.Cancer Biomarkers.  9:21-39. 2010
2010 Translational pathology of early cancer.Cancer Biomarkers.  9:1-4. 2010
2010 Translational pathology of neoplasia.Cancer Biomarkers.  9:7-20. 2010
2009 Dual effects of TGF-beta on ERalpha-mediated estrogenic transcriptional activity in breast cancer.Molecular Cancer.  8:111. 2009
2009 Combined effects of formalin fixation and tissue processing on immunorecognition Fixation effects on immunostainingStain technology.  84:223-247. 2009
2009 Anosmin-1 involved in neuronal cell migration is hypoxia inducible and cancer regulated.Cell Cycle.  8:3770-3776. 2009
2009 Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines.International Journal of Cancer.  125:2288-2295. 2009
2009 Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance.Diabetes.  58:2498-2505. 2009
2009 Experimental cancer therapy using restoration of NAD+ -linked 15-hydroxyprostaglandin dehydrogenase expression.Molecular Cancer Therapeutics.  8:3130-3139. 2009
2009 Immature myeloid cells induced by a high-fat diet contribute to liver inflammation.Hepatology.  50:1412-1420. 2009
2009 CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.Cancer Gene Therapy.  16:794-805. 2009
2009 Combined effects of formalin fixation and tissue processing on immunorecognition.Stain technology.  84:223-247. 2009
2009 Special symposium: fixation and tissue processing models.Stain technology.  84:185-193. 2009
2009 Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion.Cancer Letters.  283:29-35. 2009
2009 Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis.Scandinavian Journal of Immunology.  70:309-316. 2009
2009 Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model.International Journal of Gynecological Cancer.  19:814-819. 2009
2009 Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1.Molecular Pharmacology.  76:81-90. 2009
2009 How to efficiently obtain human tissues to support specific biomedical research projects.Cancer Epidemiology, Biomarkers and Prevention.  18:1676-1679. 2009
2009 Induction of myeloid-derived suppressor cells by tumor exosomes.International Journal of Cancer.  124:2621-2633. 2009
2009 Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer.Molecular and Cellular Biology.  29:2673-2693. 2009
2009 Immunohistochemical expression of rabphilin-3A-like (Noc2) in normal and tumor tissues of human endocrine pancreas.Stain technology.  84:39-45. 2009
2009 Prognostic significance of p53 codon 72 polymorphism differs with race in colorectal adenocarcinoma.Clinical Cancer Research.  15:2406-2416. 2009
2009 Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome.Gastroenterology.  136:1070-1080. 2009
2009 CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth.Molecular Cancer Therapeutics.  8:178-184. 2009
2009 Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group.Journal of Proteome Research.  8:113-117. 2009
2009 Timing of consent for the research use of surgically removed tissue: is postoperative consenting acceptable?Cancer.  115:4-9. 2009
2008 Erratum: The efficient operation of the surgical pathology gross room (Biotechnic and Histochemistry vol. 82(3) (71-82))Stain technology.  83:209. 2008
2008 Modulation of tumor cell growth in vivo by extracellular matrix metalloprotease inducer.Archives of Otolaryngology Head and Neck Surgery.  134:1218-1224. 2008
2008 Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging.Cancer Research.  68:8369-8376. 2008
2008 Thymus exosomes-like particles induce regulatory T cells.Journal of Immunology.  181:5242-5248. 2008
2008 Applying proteomic-based biomarker tools for the accurate diagnosis of pancreatic cancer.Journal of Gastrointestinal Surgery.  12:1683-1690. 2008
2008 Breast tumor xenografts: diffusion-weighted MR imaging to assess early therapy with novel apoptosis-inducing anti-DR5 antibody.Radiology.  248:844-851. 2008
2008 Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors.Cancer Research.  68:6232-6240. 2008
2008 Quality Assurance in Tissue Resources Supporting Biomedical Research.Cell Preservation Technology.  6:113-118. 2008
2008 mtDNA sequence variants in subtypes of epithelial ovarian cancer stages in relation to ethnic and age difference.Diagnostic Pathology.  3:32. 2008
2008 Immunohistochemistry in the evaluation of neovascularization in tumor xenografts.Stain technology.  83:179-189. 2008
2008 Quality assurance in tissue resources supporting biomedical researchCell Preservation Technology.  6:113-118. 2008
2008 Effect of exercise and calorie restriction on biomarkers of aging in mice.AJP - Regulatory, Integrative and Comparative Physiology.  294:R1618-R1627. 2008
2008 Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change.Biochemical Journal.  411:361-369. 2008
2008 The efficient operation of the surgical pathology gross room.Stain technology.  83:71-82. 2008
2008 Anti-tumor activity of the TRA-8 anti-DR5 antibody in combination with cisplatin in an ex vivo human cervical cancer model.Gynecologic Oncology.  108:591-597. 2008
2008 Antibody responses of variable lymphocyte receptors in the lamprey.Nature Immunology.  9:319-327. 2008
2008 p53 Nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behavior.Journal of Histochemistry and Cytochemistry.  56:305-312. 2008
2008 Immunohistochemical detection of EGFR, p185(erbB-2), Bcl-2 and p53 in breast carcinomas in pre-menopausal and post-menopausal women.Stain technology.  83:5-14. 2008
2008 A standards based ontological approach to information handling for use by organizations providing human tissue for research.Cancer Informatics.  6:127-137. 2008
2008 Analytical validation of serum proteomic profiling for diagnosis of prostate cancer: sources of sample bias.Clinical Chemistry.  54:44-52. 2008
2008 Clinical significance of a novel single nucleotide polymorphism in the 5' untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinoma.Frontiers in Bioscience.  13:1050-1061. 2008
2008 Mandatory fortification with folic acid in the United States is associated with increased expression of DNA methyltransferase-1 in the cervix.Nutrition.  24:94-99. 2008
2008 SELDI-TOF MS whole serum proteomic profiling with IMAC surface does not reliably detect prostate cancer.Clinical Chemistry.  54:53-60. 2008
2007 Hedgehog pathway expression in heterogeneous pancreatic adenocarcinoma: implications for the molecular analysis of clinically available biopsies.Diagnostic Molecular Pathology.  16:229-237. 2007
2007 Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis.Cell Cycle.  6:2944-2952. 2007
2007 Role of microvascular density in nonlocalizing parathyroid sestamibi scans.Laryngoscope.  117:2163-2168. 2007
2007 TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth.Molecular Cancer Therapeutics.  6:3198-3207. 2007
2007 Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice.Mechanisms of Ageing and Development.  128:672-680. 2007
2007 Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.Cancer Research.  67:9407-9416. 2007
2007 Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer.Clinical Cancer Research.  13:5535s-5543s. 2007
2007 Assessment of biomarker expression in predicting pathologic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer.Breast Journal.  13:534-535. 2007
2007 Erratum: SIRT1 is significantly elevated in mouse and human prostate cancer (Cancer Research (2007) 67, (6612-6618))Cancer Research.  67:8423. 2007
2007 Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia.Cancer Research.  67:8121-8130. 2007
2007 SIRT1 is significantly elevated in mouse and human prostate cancer.Cancer Research.  67:6612-6618. 2007
2007 Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity.BBA - Biochimica et Biophysica Acta.  1773:1116-1123. 2007
2007 Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer.Molecular Cancer.  6:40. 2007
2007 Tumor exosomes inhibit differentiation of bone marrow dendritic cells.Journal of Immunology.  178:6867-6875. 2007
2007 Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host.Blood.  109:4336-4342. 2007
2007 Efficacy of anti-death receptor 5 (DR5) antibody (TRA-8) against primary human ovarian carcinoma using a novel ex vivo tissue slice model.Gynecologic Oncology.  105:291-298. 2007
2007 Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies.Journal of Immunology.  178:5357-5365. 2007
2007 Comparison of predicted probabilities of proportional hazards regression and linear discriminant analysis methods using a colorectal cancer molecular biomarker database.Cancer Informatics.  3:115-122. 2007
2007 Plasma protein profiles differ between women diagnosed with cervical intraepithelial neoplasia (cin) 1 and 3.Cancer Informatics.  2:345-349. 2007
2007 Discrimination between benign and malignant prostate tissue using chromatin texture analysis in 3-D by confocal laser scanning microscopy.Prostate.  67:248-254. 2007
2007 Methionine inhibits cellular growth dependent on the p53 status of cells.American Journal of Surgery.  193:274-283. 2007
2007 Control of prostate cell growth: BMP antagonizes androgen mitogenic activity with incorporation of MAPK signals in Smad1.EMBO Journal.  26:346-357. 2007
2007 African-American and Caucasian disparities in colorectal cancer mortality and survival by data source: an epidemiologic review.Cancer Biomarkers.  3:301-313. 2007
2006 Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM).Journal of Neuro-Oncology.  80:261-274. 2006
2006 Plasma protein profiles differ between women diagnosed with cervical intraepithelial neoplasia (CIN) 1 and 3Cancer Informatics.  2:421-425. 2006
2006 Oncolytic HSV-1 for the treatment of brain tumours.Herpes -Cambridge-.  13:66-71. 2006
2006 Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates.American Journal of Clinical Pathology.  126:572-579. 2006
2006 Mucinous expression in benign and neoplastic glandular lesions of the uterine cervix.Archives of Pathology and Laboratory Medicine.  130:1510-1515. 2006
2006 JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha.American Journal of Pathology.  169:889-902. 2006
2006 Celecoxib inhibits cellular growth, decreases Ki-67 expression and modifies apoptosis in ovarian cancer cell lines.Archives of Medical Research.  37:689-695. 2006
2006 Erratum: A membrane form of TNF-α presented by exosomes delays T cell activation-induced cell death (Journal of Immunology (2006) 176 (7385-7393))Journal of Immunology.  177:2025. 2006
2006 Ovarian expression of markers associated with proliferation or apoptosis in women with diminished ovarian reserve.Fertility and Sterility.  86:176-185. 2006
2006 Phenotypic expression of Bax is a predictive marker of 5-fluorouracil treatment in colorectal cancer.Journal of Clinical Oncology.  24:3605. 2006
2006 A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death.Journal of Immunology.  176:7385-7393. 2006
2006 Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model.Gynecologic Oncology.  101:46-54. 2006
2006 Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma.Journal of Molecular Diagnostics.  8:76-83. 2006
2006 Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function.Journal of Immunology.  176:1375-1385. 2006
2006 Biomarkers in diagnosis of pancreatic carcinoma in fine-needle aspirates: A translational research applicationAmerican Journal of Clinical Pathology.  126:572-579. 2006
2006 Cell density influences the effect of celecoxib in two carcinoma cell lines.Stain technology.  81:51-54. 2006
2006 Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesis.Cancer Biomarkers.  2:259-266. 2006
2006 Ovarian biopsy in infertile patients with ovarian dysfunction.International Journal of Gynecologic Pathology.  25:90-94. 2006
2005 Pattern of nonspecific (or global) DNA methylation in oral carcinogenesis.Head & neck surgery.  27:1061-1067. 2005
2005 Selective cyclooxygenase-2 inhibition produces heterogeneous erythema response to ultraviolet irradiation.Journal of Investigative Dermatology.  125:1317-1320. 2005
2005 Phase I study of 90Y-CC49 monoclonal antibody therapy in patients with advanced non-small cell lung cancer: effect of chelating agents and paclitaxel co-administration.Cancer Biotherapy and Radiopharmaceuticals.  20:467-478. 2005
2005 Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts.American Journal of Pathology.  167:705-719. 2005
2005 Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: initial examination of celecoxib as a chemopreventive agent.Gynecologic Oncology.  98:376-382. 2005
2005 Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.Oncogene.  24:5589-5605. 2005
2005 Cholangiocyte endothelin 1 and transforming growth factor beta1 production in rat experimental hepatopulmonary syndrome.Gastroenterology.  129:682-695. 2005
2005 Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor-alpha-positive breast cancer cells.Journal of Biological Chemistry.  280:27022-27028. 2005
2005 Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors.Gene Therapy.  12:1042-1048. 2005
2005 High-grade tumor differentiation is an indicator of poor prognosis in African Americans with colonic adenocarcinomas.Cancer.  103:2163-2170. 2005
2005 Best practices for repositories I: Collection, storage, and retrieval of human biological materials for researchCell Preservation Technology.  3:5-48. 2005
2005 Genetic segregation of spontaneous erosive arthritis and generalized autoimmune disease in the BXD2 recombinant inbred strain of mice.Scandinavian Journal of Immunology.  61:128-138. 2005
2005 Serum levels of an isoform of apolipoprotein A-II as a potential marker for prostate cancer.Clinical Cancer Research.  11:1073-1085. 2005
2005 19 Role of Immunohistochemical Expression of Lewis Y Antigen in Ovarian CarcinomaHandbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas.  4:465-471. 2005
2005 Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor.Cancer Gene Therapy.  12:26-34. 2005
2005 Development of 3D chromatin texture analysis using confocal laser scanning microscopy.Analytical and Quantitative Cytology and Histology.  27:335-345. 2005
2005 Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancerCancer Biology and Therapy.  4:65-69. 2005
2005 Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer.Cancer Biology and Therapy.  4:65-69. 2005
2005 Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility.Clinical Chemistry.  51:102-112. 2005
2005 Implementation of accurate and fast DNA cytometry by confocal microscopy in 3D.Analytical and Quantitative Cytology and Histology.  27:225-230. 2005
2005 Novel approaches to smoothing and comparing SELDI TOF spectra.Cancer Informatics.  1:78-85. 2005
2005 Patterns of global DNA and histone methylation appear to be similar in normal, dysplastic and neoplastic oral epithelium of humans.Disease Markers.  21:147-151. 2005
2005 Recurrence and survival predictive value of phenotypic expression of Bcl-2 varies with tumor stage of colorectal adenocarcinoma.Cancer Biomarkers.  1:241-250. 2005
2005 the need for review and understanding of SELDI/MALDI mass spectroscopy data prior to analysis.Cancer Informatics.  1:86-97. 2005
2004 Expression and functional role of CCR9 in prostate cancer cell migration and invasion.Clinical Cancer Research.  10:8743-8750. 2004
2004 Adenovirus-mediated FLT1-targeted proapoptotic gene therapy of human prostate cancer.Molecular Therapy.  10:1059-1070. 2004
2004 CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion.Laboratory Investigation.  84:1666-1676. 2004
2004 Spontaneous pregnancy in a woman with premature ovarian failure: a case report.Journal of Reproductive Medicine.  49:989-991. 2004
2004 Breast cancer chemoprevention phase I evaluation of biomarker modulation by arzoxifene, a third generation selective estrogen receptor modulator.Clinical Cancer Research.  10:5403-5417. 2004
2004 Clarification in the point/counterpoint discussion related to surface-enhanced laser desorption/ionization time-of-flight mass spectrometric identification of patients with adenocarcinomas of the prostate.Clinical Chemistry.  50:1475-1476. 2004
2004 Postsurgical disparity in survival between African Americans and Caucasians with colonic adenocarcinoma.Cancer.  101:66-76. 2004
2004 Promoter hypermethylation profile of kidney cancer.Clinical Cancer Research.  10:3972-3979. 2004
2004 The role of endothelin-1 and the endothelin B receptor in the pathogenesis of hepatopulmonary syndrome in the rat.Hepatology.  39:1593-1602. 2004
2004 Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer.Clinical Cancer Research.  10:2709-2719. 2004
2004 Establishing a tumour bank: banking, informatics and ethics.British Journal of Cancer.  90:1115-1119. 2004
2004 Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor.Cancer Research.  64:1781-1787. 2004
2004 Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells.International Journal of Radiation Oncology - Biology - Physics.  58:950-958. 2004
2004 Expression of sperm protein 17 (Sp17) in ovarian cancer.International Journal of Cancer.  108:805-811. 2004
2004 IL-12 inhibits thymic involution by enhancing IL-7- and IL-2-induced thymocyte proliferation.Journal of Immunology.  172:2909-2916. 2004
2004 Prognostic significance of p27(kip-1) expression in colorectal adenocarcinomas is associated with tumor stage.Clinical Cancer Research.  10:1743-1752. 2004
2004 Intratumor heterogeneity of biomarker expression in breast carcinomas.Stain technology.  79:25-36. 2004
2004 Confocal 3D DNA cytometry: assessment of required coefficient of variation by computer simulation.Analytical and Quantitative Cytology and Histology.  26:93-99. 2004
2003 MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration.Cancer.  99:365-371. 2003
2003 Analysis of pulmonary heme oxygenase-1 and nitric oxide synthase alterations in experimental hepatopulmonary syndrome.Gastroenterology.  125:1441-1451. 2003
2003 Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer modelClinical Cancer Research.  9:3731-3741. 2003
2003 Expression of CEA, Tag-72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinoma.Human Pathology.  34:1016-1021. 2003
2003 LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer.Journal of Biological Chemistry.  278:36868-36875. 2003
2003 Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model.Clinical Cancer Research.  9:3731-3741. 2003
2003 Expression of extracellular matrix metalloprotease inducer in laryngeal squamous cell carcinoma.Laryngoscope.  113:1406-1410. 2003
2003 Inhibition of tumorigenicity by the 5'-untranslated RNA of the human c-myc P0 transcript.Experimental Cell Research.  288:131-142. 2003
2003 Erratum: Cellular mechanism of thymic involution (Scandinavian Journal of Immunology (2003) 57 (410-422))Scandinavian Journal of Immunology.  58:118. 2003
2003 Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity.Clinical Cancer Research.  9:2701-2710. 2003
2003 Cellular mechanism of thymic involution.Scandinavian Journal of Immunology.  57:410-422. 2003
2003 Increased pulmonary vascular endothelin B receptor expression and responsiveness to endothelin-1 in cirrhotic and portal hypertensive rats: a potential mechanism in experimental hepatopulmonary syndrome.Journal of Hepatology.  38:556-563. 2003
2003 Smad4 as a transcription corepressor for estrogen receptor alpha.Journal of Biological Chemistry.  278:15192-15200. 2003
2003 MacLennan et al report on an elevated incidence of prostate cancer among workers in a triazine manufacturing plant.Journal of Occupational and Environmental Medicine.  45:343-344. 2003
2003 Aging, immunity, and tumor susceptibility.Immunology and Allergy Clinics of North America.  23:83-vi. 2003
2003 Race- and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States).Cancer Causes and Control.  14:37-42. 2003
2003 The efficacy of 9-cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: results of a randomized double-blind clinical trial.Cancer Epidemiology, Biomarkers and Prevention.  12:114-119. 2003
2003 The response of extracellular signal-regulated kinase (ERK) to androgen-induced proliferation in the androgen-sensitive prostate cancer cell line, LNCaP.Stain technology.  78:11-16. 2003
2003 The use of dimethylsulfoxide as a vehicle in cell culture experiments using ovarian carcinoma cell lines.Stain technology.  78:17-21. 2003
2003 Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokers.Chest.  123:181-186. 2003
2003 Receiver operating characteristic (ROC) to determine cut-off points of biomarkers in lung cancer patients.Disease Markers.  19:273-278. 2003
2003 Risk biomarker assessment for breast cancer progression: replication precision of nuclear morphometry.Analytical and Quantitative Cytology and Histology.  25:129-138. 2003
2003 Serum protein expression profiling for cancer detection: validation of a SELDI-based approach for prostate cancer.Disease Markers.  19:185-195. 2003
2003 p53 and erbB-2 are not associated in matched cases of primary and metastatic ovarian carcinomas.Disease Markers.  19:11-17. 2003
2002 Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation.International Journal of Radiation Oncology - Biology - Physics.  54:1180-1193. 2002
2002 Analysis of the molecular quality of human tissues: an experience from the Cooperative Human Tissue Network.American Journal of Clinical Pathology.  118:733-741. 2002
2002 Cancer incidence among triazine herbicide manufacturing workers.Journal of Occupational and Environmental Medicine.  44:1048-1058. 2002
2002 A phase I trial of the single-chain immunotoxin SGN-10 (BR96 sFv-PE40) in patients with advanced solid tumors.Clinical Cancer Research.  8:3092-3099. 2002
2002 A phase II breast cancer chemoprevention trial of oral alpha-difluoromethylornithine: breast tissue, imaging, and serum and urine biomarkers.Clinical Cancer Research.  8:3105-3117. 2002
2002 A pilot study of ovarian cancer chemoprevention using medroxyprogesterone acetate in an avian model of spontaneous ovarian carcinogenesis.Gynecologic Oncology.  87:57-63. 2002
2002 BXD recombinant inbred mice represent a novel T cell-mediated immune response tumor model.International Journal of Cancer.  101:270-279. 2002
2002 A Phase I study of combined modality (90)Yttrium-CC49 intraperitoneal radioimmunotherapy for ovarian cancer.Clinical Cancer Research.  8:2806-2811. 2002
2002 The pattern of expression of Mn and Cu-Zn superoxide dismutase varies among squamous cell cancers of the lung, larynx, and oral cavity.Head & neck surgery.  24:859-867. 2002
2002 Transforming growth factor-alpha: a surrogate endpoint biomarker?Journal of The American College of Surgeons.  195:149-158. 2002
2002 Down-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer.Journal of Biological Chemistry.  277:25431-25438. 2002
2002 Paradigms for primary prevention of ovarian carcinoma.CA: A Cancer Journal for Clinicians.  52:216-225. 2002
2002 Review of the 2002 Annual Meeting of the Biological Stain Commission.Stain technology.  77:181-182. 2002
2002 Gamma camera dual imaging with a somatostatin receptor and thymidine kinase after gene transfer with a bicistronic adenovirus in mice.Radiology.  223:417-425. 2002
2002 Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.Clinical Cancer Research.  8:734-744. 2002
2002 Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal women.International Journal of Cancer.  98:118-127. 2002
2002 Quantitation of cytosine deaminase mRNA by real-time reverse transcription polymerase chain reaction: a sensitive method for assessing 5-fluorocytosine toxicity in vitro.Analytical Biochemistry.  301:189-199. 2002
2002 Molecular staging of colorectal cancer in African-American and Caucasian patients using phenotypic expression of p53, Bcl-2, MUC-1 AND p27(kip-1).International Journal of Cancer.  97:403-409. 2002
2002 10 Role of global methylation of dma in lung carcinomaHandbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas.  1:181-187. 2002
2002 Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology.Nutrition and Cancer.  43:67-75. 2002
2002 Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents.Clinical Cancer Research.  8:202-209. 2002
2001 Protease-activated receptor 2, a receptor involved in melanosome transfer, is upregulated in human skin by ultraviolet irradiation.Journal of Investigative Dermatology.  117:1412-1420. 2001
2001 Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas.Clinical Cancer Research.  7:3495-3503. 2001
2001 Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo.Nature Biotechnology.  19:838-842. 2001
2001 Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.Human Pathology.  32:856-862. 2001
2001 Intraperitoneal radioimmunochemotherapy of ovarian cancer: a phase I study.Cancer Biotherapy and Radiopharmaceuticals.  16:305-315. 2001
2001 Molecular differences in mucoepidermoid carcinoma and adenoid cystic carcinoma of the major salivary glands.Laryngoscope.  111:1373-1378. 2001
2001 Avoiding biohazards in medical, veterinary and research laboratories.Stain technology.  76:183-206. 2001
2001 Genetic dissection of age-related changes of immune function in mice.Scandinavian Journal of Immunology.  54:10-20. 2001
2001 Immunohistochemical expression of molecular markers in an avian model: a potential model for preclinical evaluation of agents for ovarian cancer chemoprevention.Gynecologic Oncology.  81:373-379. 2001
2001 Molecular biomarkers for breast cancer prognosis: coexpression of c-erbB-2 and p53.Annals of Surgery.  233:630-638. 2001
2001 Bayesian monitoring of a phase 2 chemoprevention trial in high-risk cohorts for prostate cancer.Urology.  57:220-223. 2001
2001 Bayesian monitoring of a phase 2 chemoprevention trial in high-risk cohorts for prostate cancer.Urology.  57:220-223. 2001
2001 Characterization of the cyclooxygenase-2 promoter in an adenoviral vector and its application for the mitigation of toxicity in suicide gene therapy of gastrointestinal cancers.Molecular Therapy.  3:385-394. 2001
2001 Effects of acute and chronic body weight gain reductions in the evaluation of agents for efficacy in mammary cancer prevention.Oncology Reports.  8:373-379. 2001
2001 Effects of time and temperature during attachment of sections to microscope slides on immunohistochemical detection of antigens.Stain technology.  76:55-58. 2001
2001 Fatty acid synthase: an early molecular marker of progression of prostatic adenocarcinoma to androgen independence.Journal of Urology, The.  165:1027-1032. 2001
2001 Advanced concepts in fixation: 1. Effects of fixation on immunohistochemistry, reversibility of fixation and recovery of proteins, nucleic acids, and other molecules from fixed and processed tissues. 2. Developmental methods of fixationJournal of Histotechnology.  24:201-210. 2001
2001 Introduction to the theory and practice of fixation of tissuesJournal of Histotechnology.  24:173-190. 2001
2001 Molecular characterization of colorectal neoplasia in translational research.Archives of Pathology and Laboratory Medicine.  125:91-98. 2001
2001 The effect of isolated soy protein on plasma biomarkers in elderly men with elevated serum prostate specific antigen.Journal of Urology, The.  165:294-300. 2001
2001 The effects of tissue processing variables other than fixation on histochemical staining and immunohistochemical detection of antigensJournal of Histotechnology.  24:213-219. 2001
2001 The use of fixatives in diagnostic pathologyJournal of Histotechnology.  24:151-152. 2001
2000 A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo.Molecular Therapy.  2:562-578. 2000
2000 Increase of GKLF messenger RNA and protein expression during progression of breast cancer.Cancer Research.  60:6488-6495. 2000
2000 Immunohistochemical evaluation of global DNA methylation: comparison with in vitro radiolabeled methyl incorporation assay.Stain technology.  75:251-258. 2000
2000 BC1-2 expression is associated with improved prognosis in patients with distal colorectal adenocarcinomasInternational Journal of Cancer.  89:423-430. 2000
2000 Racial differences in the prognostic usefulness of MUC1 and MUC2 in colorectal adenocarcinomas.Clinical Cancer Research.  6:4017-4025. 2000
2000 Bcl-2 expression is associated with improved prognosis in patients with distal colorectal adenocarcinomas.International Journal of Cancer.  89:423-430. 2000
2000 Methods of antigen recovery vary in their usefulness in unmasking specific antigens in immunohistochemistry.Applied Immunohistochemistry and Molecular Morphology.  8:236-243. 2000
2000 The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung.Human Pathology.  31:1068-1073. 2000
2000 Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors.Cancer Research.  60:4305-4310. 2000
2000 Longitudinal analysis of mammary cancer multiplicity in chemoprevention studies.Anticancer Research.  20:2281-2287. 2000
2000 The accumulation of ascorbic acid by squamous cell carcinomas of the lung and larynx is associated with global methylation of DNA.Cancer.  89:171-176. 2000
2000 Fractionated radiation therapy in combination with adenoviral delivery of the cytosine deaminase gene and 5-fluorocytosine enhances cytotoxic and antitumor effects in human colorectal and cholangiocarcinoma models.Gene Therapy.  7:1019-1026. 2000
2000 Noninvasive monitoring of gene transfer using a reporter receptor imaged with a high-affinity peptide radiolabeled with 99mTc or 188Re.Journal of Nuclear Medicine.  41:887-895. 2000
2000 The expression of Ep-CAM (17-1A) in squamous cell cancers of the lung.Human Pathology.  31:482-487. 2000
2000 The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanoma.Oncogene.  19:1419-1427. 2000
2000 Localized folate and vitamin B-12 deficiency in squamous cell lung cancer is associated with global DNA hypomethylation.Nutrition and Cancer.  37:99-107. 2000
1999 Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation.Cancer Biotherapy and Radiopharmaceuticals.  14:451-463. 1999
1999 Ep-Cam levels in prostatic adenocarcinoma and prostatic intraepithelial neoplasia.Journal of Urology, The.  162:1462-1466. 1999
1999 Phase II study of interferon-enhanced 131I-labeled high affinity CC49 monoclonal antibody therapy in patients with metastatic prostate cancer.Clinical Cancer Research.  5:3254s-3258s. 1999
1999 Transforming growth factor alpha (TGF-alpha) expression in dysplastic oral leukoplakia: modulation by 13-cis retinoic acid.Head & neck surgery.  21:566-573. 1999
1999 Androgenic regulation of growth factor and growth factor receptor expression in the CWR22 model of prostatic adenocarcinoma.International Journal of Cancer.  82:424-429. 1999
1999 Fatty acid synthase expression is increased in neoplastic lesions of the oral tongue.Head & neck surgery.  21:325-329. 1999
1999 Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF.Cell Growth and Differentiation.  10:423-434. 1999
1999 Specific membrane receptor gene expression targeted with radiolabeled peptide employing the erbB-2 and DF3 promoter elements in adenoviral vectors.Cancer Gene Therapy.  6:209-219. 1999
1999 Recommended policies for uses of human tissue in research, education, and quality control. Ad Hoc Committee on Stored Tissue, College of American Pathologists.Archives of Pathology and Laboratory Medicine.  123:296-300. 1999
1999 Changes in cyclin dependent kinase inhibitors p21 and p27 during the castration induced regression of the CWR22 model of prostatic adenocarcinoma.Journal of Urology, The.  161:945-949. 1999
1999 Evaluation of biomarker modulation by fenretinide in prostate cancer patients.European Urology.  35:429-438. 1999
1998 Nuclear accumulation of p53 in colorectal adenocarcinoma: prognostic importance differs with race and location of the tumor.Cancer.  83:2456-2467. 1998
1998 Genetic induction of antigens and receptors as targets for cancer radiotherapyTumor Targeting.  3:122-137. 1998
1998 Providing human tissues for research: how to establish a program.Archives of Pathology and Laboratory Medicine.  122:1065-1076. 1998
1998 Radiosensitization mediated by a transfected anti-erbB-2 single-chain antibody in vitro and in vivo.International Journal of Radiation Oncology - Biology - Physics.  42:817-822. 1998
1998 Models for early chemoprevention trials in breast cancer.Hematology/Oncology Clinics of North America.  12:993-1017. 1998
1998 Chimeric antibodies with specificity for tumor antigens: demonstration of in situ localization to tumors after antibody therapy.Stain technology.  73:186-197. 1998
1997 Ductal distribution of annexin IIIFederation proceedings.  11. 1997
1997 Aging alters zonation in the adrenal cortex of men.Journal of Clinical Endocrinology and Metabolism.  82:3898-3901. 1997
1997 Hormone levels and mammary epithelial cell proliferation in rats treated with a regimen of estradiol and progesterone that mimics the preventive effect of pregnancy against mammary cancerAnticancer Research.  17:4639-4645. 1997
1997 Hormone levels and mammary epithelial cell proliferation in rats treated with a regimen of estradiol and progesterone that mimics the preventive effect of pregnancy against mammary cancer.Anticancer Research.  17:4639-4645. 1997
1997 Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinoma.International Journal of Cancer.  74:346-358. 1997
1997 Expression of nitric oxide synthase III in human thyroid follicular cells: evidence for increased expression in hyperthyroidism.European Journal of Endocrinology.  136:649-655. 1997
1997 Re: loss of tumor marker-immunostaining intensity on stored paraffin slides of breast cancer.JNCI: Journal of the National Cancer Institute.  89:585-586. 1997
1997 Intraperitoneal radioimmunotherapy of ovarian cancer with 177Lu-CC49: a phase I/II study.Gynecologic Oncology.  65:94-101. 1997
1997 The use of biomarker expression to characterize neoplastic processes.Stain technology.  72:96-104. 1997
1997 A novel gene therapy strategy for elimination of prostate carcinoma cells from human bone marrow.Human Gene Therapy.  8:157-170. 1997
1997 Assessment of genomic damage in colorectal cancer by DNA fingerprinting: Prognostic applicationsJournal of Clinical Oncology.  15:3230-3240. 1997
1996 The effects of dihydrotestosterone on the expression of p185(erbB-2) and c-erbB-2 mRNA in the prostatic cell line LNCaP.Journal of Steroid Biochemistry and Molecular Biology.  59:441-447. 1996
1996 Phase II study of dual 131I-labeled monoclonal antibody therapy with interferon in patients with metastatic colorectal cancer.Clinical Cancer Research.  2:1811-1818. 1996
1996 Elevated serum levels of p105(erbB-2) in patients with advanced-stage prostatic adenocarcinoma.International Journal of Cancer.  69:398-402. 1996
1996 Expression of nm23-H1 in prostatic intraepithelial neoplasia and adenocarcinoma.Human Pathology.  27:1021-1024. 1996
1996 The pathologist's role in the use of human tissues in research--legal, ethical, and other issues.Archives of Pathology and Laboratory Medicine.  120:909-912. 1996
1996 Effects of fixation and tissue processing on immunohistochemical demonstration of specific antigens.Stain technology.  71:224-230. 1996
1996 Intraperitoneal radioimmunotherapy of ovarian cancer with lutetium-177-CC49.Journal of Nuclear Medicine.  37:1491-1496. 1996
1996 CD44 expression in dysplastic epithelium and squamous-cell carcinoma of the esophagus.International Journal of Cancer.  69:254-258. 1996
1996 CD44 expression in dysplastic epithelium and squamous-cell carcinoma of the esophagus.International Journal of Cancer.  69:254-258. 1996
1996 Enhancement of radiolabeled antibody binding and tumor localization through adenoviral transduction of the human carcinoembryonic antigen gene.Gene Therapy.  3:567-580. 1996
1996 Effects of mutation and growth rates on patterns of microsatellite instability.American Journal of Pathology.  148:1757-1761. 1996
1996 Dissociation of cyclic inositol phosphohydrolase activity from annexin III.Journal of Biological Chemistry.  271:8295-8299. 1996
1996 Lymphoplasmacytic aortitis and acute aortic dissection. An uncommon association.Archives of Pathology and Laboratory Medicine.  120:402-404. 1996
1996 Biomarker expression in prostatic intraepithelial neoplasia.European Urology.  30:153-166. 1996
1996 Silver staining methods to identify cells of the dispersed neuroendocrine systemJournal of Histotechnology.  19:225-234. 1996
1996 Theory and practice of silver staining in histopathologyJournal of Histotechnology.  19:183-195. 1996
1995 Decreased cyclic inositol phosphohydrolase activity in hamster renal tumors and human renal cell carcinomas.Biochemical and molecular medicine.  56:104-107. 1995
1995 Nesidioblastosis causing reversal of insulin-dependent diabetes and development of hyperinsulinemic hypoglycemia.Diabetes Care.  18:1379-1380. 1995
1995 Immunocytochemical analyses of dehydroepiandrosterone sulfotransferase in cultured human fetal adrenal cells.Journal of Clinical Endocrinology and Metabolism.  80:1027-1031. 1995
1995 Lewis Y antigen as detected by the monoclonal antibody BR96 is expressed strongly in prostatic adenocarcinoma.Journal of Urology, The.  153:1572-1574. 1995
1995 Expression of tumor-associated glycoprotein 72 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma.Modern Pathology.  8:260-265. 1995
1995 Immunocytochemical analyses of dehydroepiandrosterone sulfotransferase in cultured human fetal adrenal cells.Journal of Clinical Endocrinology and Metabolism.  80:1027-1031. 1995
1995 Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice.Development.  121:505-514. 1995
1995 Immunohistochemical evaluation of the cellular localization and ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-4 isomerase in the human fetal adrenal gland.Endocrine Research.  21:69-80. 1995
1995 Erratum: Immunocytochemical analyses of dehydroepiandrosterone sulfotransferase in cultured human fetal adrenal cells (Journal of Clinical Endocrinology and Metabolism (1995) 80 (1027-1031))Journal of Clinical Endocrinology and Metabolism.  80:1971. 1995
1995 Prognostic Biomarkers in Breast Cancer: Factors Affecting Immunohistochemical EvaluationBreast Journal.  1:243-250. 1995
1994 The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary.Molecular and Cellular Endocrinology.  106:145-149. 1994
1994 Accumulation of the p53 protein occurs more frequently in metastatic than in localized prostatic adenocarcinomas.Prostate.  25:243-248. 1994
1994 FDA regulation of immunochemicals used in immunohistochemistry: our view.Stain technology.  69:348-350. 1994
1994 Expression of p160erbB-3 and p185erbB-2 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma.JNCI: Journal of the National Cancer Institute.  86:1140-1145. 1994
1994 Evaluation of thyroid nodules: Clinical considerationsPrimary Care Update for Ob Gyns.  1:161-167. 1994
1994 Counter-regulatory hormone responses to insulin-induced acute hypoglycemia in hypopituitary patients.Hormone and Metabolic Research.  26:276-282. 1994
1994 Treatment of metastatic prostate carcinoma with radiolabeled antibody CC49.Journal of Nuclear Medicine.  35:1017-1022. 1994
1994 Interactions between TGF-beta and adrenocorticotropin in growth regulation of human adrenal fetal zone cellsAmerican Journal of Physiology.  266. 1994
1994 Interactions between TGF-beta and adrenocorticotropin in growth regulation of human adrenal fetal zone cells.American Journal of Physiology.  266:E495-E500. 1994
1994 Thyroid function screening in newly admitted psychiatric inpatients.Annals of Clinical Psychiatry.  6:7-12. 1994
1994 Evaluation of biomarkers in breast and prostate cancer.Journal of Cellular Biochemistry -Supplement-.  19:259-266. 1994
1994 Immunohistochemical localization of dehydroepiandrosterone sulfotransferase in human fetal tissues.Journal of Clinical Endocrinology and Metabolism.  78:234-236. 1994
1994 Interactions between TGF-β and adrenocorticotropin in growth regulation of human adrenal fetal zone cellsAmerican Journal of Physiology.  266. 1994
1994 Retinoid modulation of biomarkers in oral leukoplakia/dysplasia.Journal of Cellular Biochemistry -Supplement-.  19:270-277. 1994
1994 The effects of coumarin and suramin on the growth of malignant renal and prostatic cell lines.Journal of Cancer Research and Clinical Oncology.  120 Suppl:S11-S13. 1994
1994 Thyroid dysfunction in nonpregnant womenPrimary Care Update for Ob Gyns.  1:45-54. 1994
1993 Expression of transforming growth factor-alpha, epidermal growth factor and the epidermal growth factor receptor in adenocarcinoma of the prostate and benign prostatic hyperplasia.Modern Pathology.  6:733-737. 1993
1993 A phase I clinical trial of murine monoclonal antibody D612 in patients with metastatic gastrointestinal cancer.Cancer Research.  53:4555-4562. 1993
1993 Direct localization comparison of murine and chimeric B72.3 antibodies in patients with colon cancer.Human antibodies and hybridomas.  4:190-197. 1993
1993 Expression of IGF-II/Man-6-P receptors on rat, rabbit, and human colon epithelial cells.American Journal of Physiology.  264:R1101-R1110. 1993
1993 The success of a clinical librarian program in an academic autopsy pathology service.American Journal of Clinical Pathology.  99:576-581. 1993
1993 The Cooperative Human Tissue Network. An update.Cancer.  71:1391-1394. 1993
1993 Expression of IGF-II/Man-6-P receptors on rat, rabbit, and human colon epithelial cellsAmerican Journal of Physiology.  264. 1993
1992 Phase I trial of the chimeric anti-GD2 monoclonal antibody ch14.18 in patients with malignant melanoma.Human antibodies and hybridomas.  3:19-24. 1992
1991 Identification of bile acid-CoA: amino acid N-acyltransferase in rat kidney.Biochemical Journal.  280 ( Pt 3):821-824. 1991
1991 Systemic absorption of insulin delivered topically to the rat eye.Investigative Ophthalmology & Visual Science.  32:3021-3027. 1991
1990 Alterations in dietary sodium affect isoproterenol-induced cardiac hypertrophy.Journal of Molecular and Cellular Cardiology.  22:1135-1145. 1990
1990 Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.Proceedings of the National Academy of Sciences.  87:7762-7766. 1990
1989 Compensatory ovarian hypertrophy occurs by a mechanism distinct from compensatory growth in the regenerating liver.American Journal of Obstetrics and Gynecology.  161:1653-1657. 1989
1989 Compensatory ovarian hypertrophy occurs by a mechanism distinct from compensatory growth in the regenerating liver.American Journal of Obstetrics and Gynecology.  161:1653-1657. 1989
1989 Receptors for insulin and insulin-like growth factor-I in the human adrenal gland.Biochemical and Biophysical Research Communications.  165:204-211. 1989
1989 Gastrointestinal autonomic nerve tumors. 'Plexosarcomas'.Archives of Pathology and Laboratory Medicine.  113:846-853. 1989
1989 Cushing's syndrome. Diagnosis of the atypical patient.Archives of Pathology and Laboratory Medicine.  113:727-728. 1989
1989 Functional and morphological studies of long-term islet allografts in the renal subcapsular space of the BB/W rat.Transplantation.  47:580-582. 1989
1989 Special communication. The Cooperative Human Tissue Network.Cancer.  63:1452-1455. 1989
1989 Dietary fish oil inhibits bleomycin-induced pulmonary fibrosis in the rat.Experimental Lung Research.  15:315-329. 1989
1989 Colonic absorption of insulin: an in vitro and in vivo evaluation.Journal of Pharmacology and Experimental Therapeutics.  248:567-572. 1989
1989 Unsuspected Cushing's disease in a patient with fatal staphylococcal bacteremia and multiple pituitary adenomas.American Journal of Medicine.  86:217-221. 1989
1989 Unsuspected Cushing's disease in a patient with fatal staphylococcal bacteremia and multiple pituitary adenomas.American Journal of Medicine.  86:217-221. 1989
1988 Guidelines to avoid personnel contamination by infective agents in research laboratories that use human tissuesJournal of tissue culture methods : Tissue Culture Association manual of cell, tissue, and organ culture procedures.  11:191-199. 1988
1988 Neuroendocrine differentiation in prostatic carcinomas. A retrospective autopsy study.Archives of Pathology and Laboratory Medicine.  112:1100-1105. 1988
1988 Pathology of the adrenal gland.Seminars in Roentgenology.  23:323-331. 1988
1988 Lactate dehydrogenase isolated from human liver mitochondria: its purification and partial biochemical characterization.Clinical Biochemistry.  21:231-237. 1988
1988 Distribution of receptors for insulin and insulin-like growth factor I (somatomedin C) in the adrenal gland.Biochemical and Biophysical Research Communications.  154:138-145. 1988
1988 Effect of haemolysis on radioimmunoassay for insulin.Diabetologia.  31:403-404. 1988
1988 Paradoxical organ-specific adaptations to streptozotocin diabetes mellitus in adult rats.American Journal of Physiology.  254:E749-E755. 1988
1988 Paradoxical organ-specific adaptations to streptozotocin diabetes mellitus in adult rats.American Journal of Physiology.  254:E749-E755. 1988
1988 Demonstration of the adenosine reservoirs with nitrobenzylthioinosine in liver and diaphragm by high-performance liquid chromatography.J Chromatogr.  426:249-258. 1988
1988 Tachybrady-arrhythmias and "spells" in a 47-year-old man.The Alabama journal of medical sciences.  25:151-158. 1988
1988 Modulation of the development of bleomycin-induced fibrosis by deferoxamine.Toxicology and Applied Pharmacology.  92:358-367. 1988
1988 Stability and electrophoretic characteristics of creatine kinase BB extracted from human brain and intestine.Clinical Chemistry.  34:489-492. 1988
1988 Methods of measuring thyroid hormone levels.American Journal of Psychiatry.  145:266. 1988
1988 Effect of iron deficiency on bleomycin-induced lung fibrosis in the hamster.The American review of respiratory disease.  137:85-89. 1988
1987 Availability of human tissues for research in cancer.Science.  237:10-11. 1987
1987 New developments in understanding phenytoin-induced gingival hyperplasia.Journal of the American Dental Association.  114:814-816. 1987
1987 Detection of high incidence of K-ras oncogenes during human colon tumorigenesis.Nature.  327:298-303. 1987
1987 A 35-year-old black woman with hypokalemia and accelerated hypertension.The Alabama journal of medical sciences.  24:31-40. 1987
1987 Effect of temperature on argyrophil impregnation: development of a high temperature rapid argyrophil procedure.Stain technology.  62:41-49. 1987
1987 Effects of dietary fats on bleomycin-induced pulmonary fibrosis.Experimental Lung Research.  12:149-161. 1987
1987 High incidence of c-K-ras oncogenes in human colon cancer detected by the RNAse A mismatch cleavage methodJournal of Tumor Marker Oncology.  2:113-123. 1987
1986 Elevated atypical creatine kinases.Journal of the American Medical Association.  256:3215-3216. 1986
1986 A small adrenocortical carcinoma with aggressive behavior. An evaluation of criteria for malignancy.Archives of Pathology and Laboratory Medicine.  110:1076-1079. 1986
1986 Histologic variation in the skin lesions of the glucagonoma syndrome.American Journal of Surgical Pathology.  10:445-453. 1986
1986 Cytogenetics of medullary carcinoma of the thyroid.Cancer Genetics and Cytogenetics.  20:247-253. 1986
1986 A methyl green nuclear stain for argyrophil proceduresLaboratory Medicine.  17:532-534. 1986
1985 Nonresolving Cushing's syndrome due to depot methylprednisolone verified by high-performance liquid chromatography.Southern Medical Journal.  78:1143-1144. 1985
1985 Plasmacytoid T-cell lymphoma associated with chronic myeloproliferative disorder.American Journal of Surgical Pathology.  9:380-387. 1985
1985 Cushing's syndrome. Screening methods in hospitalized patients.Archives of Pathology and Laboratory Medicine.  109:222-229. 1985
1984 Abnormal lactate dehydrogenase isoenzyme pattern in a critically ill patient.Southern Medical Journal.  77:921-923. 1984
1984 Corticotropin production by tumors of the autonomic nervous system.Archives of Pathology and Laboratory Medicine.  108:545-550. 1984
1984 LD-6 isoenzyme and lactate-independent dehydrogenase differ.Clinical Chemistry.  30:1269-1271. 1984
1984 Golden Syrian hamsters: a new experimental model for adrenal compensatory hypertrophy.Endocrinology.  114:1490-1495. 1984
1984 Aldosterone blocks adrenal compensatory hypertrophy in the rat.American Journal of Physiology.  246:E306-E310. 1984
1984 Malignant small bowel neoplasm of enteric plexus derivation (plexosarcoma). Light and electron microscopic study confirming the origin of the neoplasm.Digestive Diseases and Sciences.  29:275-284. 1984
1984 Aldosterone blocks adrenal compensatory hypertrophy in the ratAJP - Endocrinology and Metabolism.  9. 1984
1984 Clinical significance and partial biochemical characterization of lactate dehydrogenase isoenzyme 6.Clinical Chemistry.  30:46-49. 1984
1982 Functional carotid paragangliomas. Biochemical, ultrastructural, and histochemical correlation with clinical symptoms.Archives of Pathology and Laboratory Medicine.  106:599-603. 1982
1982 Radiology rounds: fever of unknown origin in a 48-year-old man seven years after mesocaval shunt.The Alabama journal of medical sciences.  19:289-295. 1982
1982 An extra-adrenal pheochromocytoma mimicking lymph node metastasis from a cervical cancer.Gynecologic Oncology.  13:416-422. 1982
1982 Squamous cell carcinoma metastatic to placenta and ovary.Obstetrics and Gynecology.  59:81S-83S. 1982
1981 Membranous nephropathy in a renal allograft. Its occurrence in a patient with previous anti-glomerular basement membrane disease.Archives of Pathology and Laboratory Medicine.  105:71-75. 1981
1978 Organization of the medial hypothalamus for control of adrenocorticotropin in the cat.Endocrinology.  103:957-970. 1978
1976 Inhibitory and facilitatory areas of the rostral pons mediating ACTH release in the cat.Endocrinology.  99:1220-1228. 1976
1975 Hypothalamic cells in an area mediating ACTH release respond to right atrial stretch.American Journal of Physiology.  228:1039-1045. 1975
1974 Inhibitory and facilitatory hypothalamic areas mediating ACTH release in the cat.Endocrinology.  95:1450-1461. 1974
1973 Localized hypothalamic area related to neural control of ACTHFederation proceedings.  32:448. 1973
1966 Wide-line NMR study of molecular motion in [Me3SiNSiMe2]2Journal of Chemical Physics.  45:1954-1960. 1966

Book

Year Title Altmetric
2013 New NSAID targets and derivatives for colorectal cancer chemoprevention..  Ed. 191.  2013

Chapter

Year Title Altmetric
2017 Biobank and expertise networks.  111-135. 2017
2017 Safety issues in biorepositories.  65-83. 2017
2016 Safety and the Biorepository.  479-492. 2016
2016 Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository..  1-38. 2016
2014 The effects of exosomes and related vesicles on cancer development, progression, and dissemination.  107-129. 2014
2013 Human tissue biorepository.  483-497. 2013
2012 Biomarkers and the genetics of early neoplastic lesions.  41-64. 2012
2012 Development and progression of colorectal neoplasia.  235-265. 2012
2009 General Considerations Concerning Safety in Biomedical Research Laboratories.  563-572. 2009
2006 Biology of breast cancer: Molecular and pathologic features of ductal neoplasia of the breast: Racial considerations.  39-70. 2006

Principal Investigator On

  • Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership: Bioethics Shared Resource  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership: Project 2: Molecular Regulation of Kaiso in Prostate Cancer  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • Comprehensive Cancer Center Core Support Grant - Tissue Procurement Shared Facility  awarded by National Cancer Institute/NIH/DHHS 2017 - 2021
  • Theranostic Nanoparticles for Detection and Treatment of Pancreatic Cancer  awarded by WAKE FOREST UNIVERSITY 2017 - 2019
  • Pulmonary Hypertension Breakthrough Initiative  awarded by Indiana University 2016 - 2019
  • Collaborative Human Tissue Network  awarded by National Cancer Institute/NIH/DHHS 2014 - 2019
  • Pulmonary Hypertension Breakthrough Initiative  awarded by University of Colorado 2014 - 2018
  • Phosphodiesterase 5: A Novel Target and Inhibitor for Breast Cancer Chemoprevention  awarded by University of South Alabama 2012 - 2017
  • Comprehensive Cancer Center Core Support Grant - Tissue Procurement Shared Facility  awarded by National Cancer Institute/NIH/DHHS 2016 - 2017
  • Transcriptional Repressor Kaiso Promotes Metastasis through Epithelial to Mesenchymal Transition  awarded by TUSKEGEE UNIVERSITY 2013 - 2016
  • Novel Sulindac Derivatives for Colon Cancer Chemoprevention  awarded by University of South Alabama 2015 - 2016
  • Biomarkers in the Detection of Prostate Cancer in African Americans  awarded by DOD - ARMY MEDICAL RESEARCH ACQUISITION ACTIVITY 2010 - 2016
  • UAB / UMN SPORE in Pancreatic Cancer - Core B  awarded by National Cancer Institute/NIH/DHHS 2010 - 2016
  • Active - Tissue Procurement - Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • UAB Skin Disease Research Center - Tissue Resources and Molecular Pathology Core - Core C  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2009 - 2015
  • A Metabolomics Approach to Define a Novel Chemopreventive Pathway  awarded by University of South Alabama 2013 - 2015
  • Private Grant  awarded by LEIDOS BIOMEDICAL RESEARCH, INC. 2014 - 2015
  • Tissue Source Site (TSS) in Support of the NCI Clinical Assay Development Program - Admin Core  awarded by SAIC - FREDERICK 2014 - 2015
  • Private Grant  awarded by LEIDOS BIOMEDICAL RESEARCH, INC. 2014 - 2015
  • Tissue Resource Site (TSS) in Support of the The Cancer Genome Atlas (TCGA) Program - Task Order 1  awarded by SAIC - FREDERICK 2013 - 2014
  • Private Grant  awarded by LEIDOS BIOMEDICAL RESEARCH, INC. 2013 - 2014
  • Center for Tissue Processing to Support Research in Pulmonary Arterial Hypertension  awarded by CARDIOVASCULAR MEDICAL RESEARCH AND EDUCATION FUND 2006 - 2014
  • Tissue Resource Site (TSS) in Support of the The Cancer Genome Atlas (TCGA) Program - Admin Core  awarded by SAIC - FREDERICK 2013 - 2014
  • Cooperative Human Tissue Network  awarded by National Cancer Institute/NIH/DHHS 2008 - 2014
  • SPORE in Breast Cancer - Tissue Core  awarded by National Cancer Institute/NIH/DHHS 2007 - 2013
  • Multicenter Genetic Epigenetic & Expression Analysis of DCIS Outcome Predictors  awarded by Johns Hopkins University 2011 - 2013
  • Private Grant  awarded by ROCKLAND IMMUNOCHEMICALS 2011 - 2012
  • The Importance of ENT in Breast Cancer in African American Women  awarded by George Washington University 2010 - 2012
  • Comprehensive Cancer Center Core Support Grant - Tissue Procurement  awarded by National Cancer Institute/NIH/DHHS 2006 - 2011
  • Investigator On

  • Sialylation-dependent Mechanisms Driving Pancreatic Cancer Progression  awarded by National Cancer Institute/NIH/DHHS 2018 - 2023
  • 3/3 Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2017 - 2021
  • Hepato/Renal Fibrocystic Diseases Core Center (UAB HRFDCC) - Admin Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2020
  • The Hepato/Renal Fibrocystic Disease Core Center (UAB HRFDCC)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2020
  • Mechanisms of Resistance to Cancer Therapeutics  awarded by National Cancer Institute/NIH/DHHS 2014 - 2019
  • UAB NRG Oncology Member Institution Purchased Service Agreement  awarded by NRG ONCOLOGY FOUNDATION 2014 - 2019
  • Breast Tumor Tissue-Derived Hedgehog Morphogens Immunoedit the Polarization of Breast Cancer Associated Macrophages  awarded by DOD - ARMY MEDICAL RESEARCH ACQUISITION ACTIVITY 2014 - 2018
  • Glycosylation-Dependent Mechanisms Regulating Ovarian Tumor Cell Survival  awarded by National Institute of General Medical Sciences/NIH/DHHS 2014 - 2018
  • Glycan Control of Stem Cell-Associated Pathways in Pancreatic Cancer  awarded by National Cancer Institute/NIH/DHHS 2015 - 2017
  • UAB / UMN SPORE in Pancreatic Cancer  awarded by National Cancer Institute/NIH/DHHS 2010 - 2017
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2016 - 2017
  • Exploring Effects of Weight Loss on Ductal Carcinoma In Situ  awarded by National Cancer Institute/NIH/DHHS 2014 - 2017
  • Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Hepato/Renal Fibrocystic Diseases Core Center (UAB HRFDCC)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2011 - 2016
  • Hepato/Renal Fibrocystic Diseases Core Center (UAB HRFDCC) - Core A  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2011 - 2016
  • Hepato/Renal Fibrocystic Diseases Core Center (UAB HRFDCC) - Core A  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2011 - 2016
  • UAB / UMN SPORE in Pancreatic Cancer - Project 1  awarded by National Cancer Institute/NIH/DHHS 2010 - 2016
  • Molecular Pathogenesis and Phenotype of Acquired CFTR Dysfunction in COPD  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2011 - 2016
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • UAB Skin Disease Research Center  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2009 - 2015
  • A Specific Screening Strategy to Reduce Prostate Cancer Mortality  awarded by DOD - ARMY MEDICAL RESEARCH ACQUISITION ACTIVITY 2012 - 2015
  • Networks of Tissue Source Site (TSS) in Support of the Cancer Genome Atlas (TCGA) Program  awarded by Washington University 2010 - 2015
  • Private Grant  awarded by LEIDOS BIOMEDICAL RESEARCH, INC. 2013 - 2014
  • TGFBR1 Signaling in Colorectal Cancer  awarded by National Cancer Institute/NIH/DHHS 2010 - 2014
  • SPORE in Breast Cancer  awarded by National Cancer Institute/NIH/DHHS 2007 - 2013
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2006 - 2012
  • Education And Training

  • Doctor of Medicine, Johns Hopkins University
  • Doctor of Philosophy in Biophysics, Johns Hopkins University
  • Vanderbilt University Medical Center, Internship 1979
  • UAB Hospital, Residency 1980
  • Full Name

  • William Grizzle
  • Blazerid

  • wgrizzle