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Wenguang Feng
Assistant Professor
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E-mail
wfeng@uab.edu
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Wenguang Feng
Assistant Professor
Positions
Associate Scientist (C)
,
Comprehensive Diabetes Center
,
School of Medicine
Associate Scientist (C)
,
Nephrology Research & Training Center
,
General Clinical Research Center
Assistant Professor (P)
,
Medicine - Nephrology
,
Department of Medicine
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2022
Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4
.
Redox Biology
. 52.
2022
2022
Sex Difference in Autoregulatory Responses of Juxtamedullary Afferent Arterioles Following Ischemia-Reperfusion in Rats
2022
2021
Cellular antioxidant mechanisms control immunoglobulin light chain-mediated proximal tubule injury
.
Free Radical Biology and Medicine
. 171:80-90.
2021
2021
Restoration of afferent arteriolar autoregulatory behavior in ischemia-reperfusion injury in rat kidneys
2021
2020
Free light chains injure proximal tubule cells through the STAT1/HMGB1/TLR axis
.
JCI Insight
. 5.
2020
2020
Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive rat
.
Kidney International
. 97:528-537.
2020
2020
COX-2-derived prostaglandins as mediators of the deleterious effects of nicotine in chronic kidney disease
2020
2019
Ferritin light chain confers protection against sepsis-induced inflammation and organ injury
.
Frontiers in Immunology
. 10.
2019
2019
Immunoglobulin light chains generate proinflammatory and profibrotic kidney injury
.
Journal of Clinical Investigation
. 129:2792-2806.
2019
2019
Induced pluripotent stem cell-derived endothelial cells attenuate lipopolysaccharide-induced acute lung injury
.
Journal of Applied Physiology
. 127:444-456.
2019
2018
Cutaneous exposure to lewisite causes acute kidney injury by invoking dna damage and autophagic response
2018
2017
Haploinsufficiency of the Transcription Factor Ets-1 Is renoprotective in dahl salt-sensitive rats
.
Journal of the American Society of Nephrology
. 28:3239-3250.
2017
2017
Novel paradigms of salt and hypertension
.
Journal of the American Society of Nephrology
. 28:1362-1369.
2017
2015
Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intake
2015
2015
Transcription factor avian erythroblastosis virus E26 oncogen homolog-1 is a novel mediator of renal injury in salt-sensitive hypertension
.
Hypertension
. 65:813-820.
2015
2014
The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistula
.
Journal of the American Society of Nephrology
. 25:475-487.
2014
2012
Role of the transcription factor erythroblastosis virus E
2
6 oncogen homolog-1 (ETS-1) as mediator of the renal proinflammatory and profibrotic effects of angiotensin II
.
Hypertension
. 60:1226-1233.
2012
2012
Estrogen modulates NFκB signaling by enhancing IκBα levels and blocking p65 binding at the promoters of inflammatory genes via estrogen receptor-β
.
PLoS One
. 7.
2012
2012
Cardiomyopathy and response to enzyme replacement therapy in a male mouse model for fabry disease
.
PLoS One
. 7.
2012
2012
Nicotine exposure and the progression of chronic kidney disease: Role of the α7-nicotinic acetylcholine receptor
2012
2012
The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cells
2012
2011
O-GlcNAc modification of nfκb p65 inhibits tnf-α-induced inflammatory mediator expression in rat aortic smooth muscle cells
.
PLoS One
. 6.
2011
2011
Environmental tobacco smoke furthers progression of diabetic nephropathy
.
American Journal of the Medical Sciences
. 341:126-130.
2011
2010
The transcription factor ETS-1 mediates proinflammatory responses and neointima formation in carotid artery endoluminal vascular injury
.
Hypertension
. 55:1381-1388.
2010
2010
Nicotine worsens the severity of nephropathy in diabetic mice: Implications for the progression of kidney disease in smokers
2010
2008
Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury
2008
2008
Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats
.
Biogerontology
. 9:139-151.
2008
2008
Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (FcγRI)-dependent
.
American Journal of Pathology
. 172:22-30.
2008
2007
Estrogen modulates TNF-α-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-β activation
2007
2007
Aged rats lose vasoprotective and anti-inflammatory actions of estrogen in injured arteries
2007
2005
Estrogen treatment abrogates neointima formation in human C-reactive protein transgenic mice
2005
2005
Cholangiocyte endothelin 1 and transforming growth factor β1 production in rat experimental hepatopulmonary syndrome
.
Gastroenterology
. 129:682-695.
2005
2004
Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells
.
Journal of Applied Physiology
. 97:1550-1558.
2004
2004
Estrogen modulates inflammatory mediator expression and neutrophil chemotaxis in injured arteries
.
Circulation
. 110:1664-1669.
2004
2003
Hormone replacement therapy and inflammation: Interactions in cardiovascular disease
.
Hypertension
. 42:657-663.
2003
Research
Research Overview
Mechanisms of Hypertensive Nephrolpathy
Principal Investigator On
Nicotine and Hypertensive Chronic Kidney Disease
awarded by
MACAU HYPERTENSION ALLIANCE
The Role of Transcription Factor ETS-1 in Arteriovenous Fistula Neointimal Hyperplasia
awarded by
American Heart Association
Background
Education And Training
Doctor of Philosophy in Physiology, Pathology and Related Sciences,
1996
Doctor of Medicine,
1989
Contact
Full Name
Wenguang
Feng