Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Astroglial vesicular network: evolutionary trends, physiology and pathophysiology 2018
2018 Enteric glia regulate gut motility in health and disease 2018
2017 Stratification of astrocytes in healthy and diseased brain 2017
2017 Two modes of enteric gliotransmission differentially affect gut physiology 2017
2017 Astrocytic face of Alzheimer's disease 2017
2017 Astroglial Vesicular Trafficking in Neurodegenerative Diseases 2017
2017 Astroglial calcium signalling in Alzheimer's disease 2017
2017 Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology 2017
2017 Homer1 scaffold proteins govern Ca2+ dynamics in normal and reactive astrocytes 2017
2017 Neuroglia: Functional paralysis and reactivity in alzheimer’s disease and other neurodegenerative pathologies 2017
2016 Ketamine Inhibits ATP-Evoked Exocytotic Release of Brain-Derived Neurotrophic Factor from Vesicles in Cultured Rat Astrocytes 2016
2016 Plasmalemmal and mitochondrial Na+-Ca2+ exchange in neuroglia 2016
2016 Tissue engineering: Nanoelectronics for the heart 2016
2016 Translational potential of astrocytes in brain disorders 2016
2016 Spatio-temporal characteristics of metabotropic glutamate receptor 5 traffic at or near the plasma membrane in astrocytes 2016
2016 Astrocytes in physiological aging and Alzheimer's disease 2016
2016 Astrocytic vesicles and gliotransmitters: Slowness of vesicular release and synaptobrevin2-laden vesicle nanoarchitecture 2016
2016 Central role of maladapted astrocytic plasticity in ischemic brain edema formation 2016
2016 Loose excitation-secretion coupling in astrocytes 2016
2016 Calcium signalling toolkits in astrocytes and spatio-temporal progression of alzheimer’s disease 2016
2016 Complex and differential glial responses in alzheimer´s disease and ageing 2016
2016 Astrocytes: a central element in neurological diseases 2016
2016 Mathematical modeling in neuroscience: Neuronal activity and its modulation by astrocytes 2016
2016 Astrocytes as secretory cells of the central nervous system: Idiosyncrasies of vesicular secretion 2016
2016 Astroglia dynamics in ageing and Alzheimer's disease 2016
2016 Expression of familial Alzheimer disease presenilin 1 gene attenuates vesicle traffic and reduces peptide secretion in cultured astrocytes devoid of pathologic tissue environment 2016
2016 Astrocytes modulate local field potential rhythm 2016
2016 Astroglia, Glutamatergic Transmission and Psychiatric Diseases 2016
2016 Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders 2016
2016 PATHOBIOLOGY OF NEURODEGENERATION: THE ROLE FOR ASTROGLIA. 2016
2015 Editorial: The role of glia in plasticity and behavior 2015
2015 Chemically functionalized single-walled carbon nanotubes enhance the glutamate uptake characteristics of mouse cortical astrocytes 2015
2015 The second brain in autism spectrum disorder: Could connexin 43 expressed in enteric glial cells play a role? 2015
2015 Diversity in the utilization of glucose and lactate in synthetic mammalian myotubes generated by engineered configurations of MyoD and E12 in otherwise non-differentiation growth conditions 2015
2015 Nanopore sensing of botulinum toxin type B by discriminating an enzymatically cleaved peptide from a synaptic protein synaptobrevin 2 derivative 2015
2015 Pitt-Hopkins mouse model has altered particular gastrointestinal transits in vivo 2015
2015 Trafficking of excitatory amino acid transporter 2-laden vesicles in cultured astrocytes: A comparison between approximate and exact determination of trajectory angles 2015
2014 Probing astroglia with carbon nanotubes: Modulation of form and function 2014
2014 Glia in the pathogenesis of neurodegenerative diseases 2014
2014 Changes in the morphology and proliferation of astrocytes induced by two modalities of chemically functionalized single-walled carbon nanotubes are differentially mediated by glial fibrillary acidic protein 2014
2014 EDITORIAL Neuroglia as a Central Element of Neurological Diseases: An Underappreciated Target for Therapeutic Intervention. 2014
2014 TRP channels coordinate ion signalling in astroglia 2014
2014 Single-vesicle architecture of synaptobrevin2 in astrocytes 2014
2014 Caenorhabditis elegans glia modulate neuronal activity and behavior 2014
2014 Neuroglia as a central element of neurological diseases: An underappreciated target for therapeutic intervention 2014
2014 Pathological role for exocytotic glutamate release from astrocytes in hepatic encephalopathy 2014
2014 Heterogeneity of myotubes generated by the MyoD and E12 basic helix-loop-helix transcription factors in otherwise non-differentiation growth conditions 2014
2014 Data and model tango to aid the understanding of astrocyte-neuron signaling 2014
2014 Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice 2014
2014 Cell-type specific mechanisms of D-serine uptake and release in the brain 2014
2014 Comparative analysis of optogenetic actuators in cultured astrocytes 2014
2014 Glutamate and ATP: The Crossroads of Signaling and Metabolism in the Brain. 2014
2014 History of electrophysiology and the patch clamp 2014
2014 Imaging of mitochondrial Ca2+ dynamics in astrocytes using cell-specific mitochondria-targeted GCaMP5G/6s: Mitochondrial Ca2+ uptake and cytosolic Ca2+ availability via the endoplasmic reticulum store 2014
2014 Neuroglia in ageing and disease 2014
2014 Neurological and psychiatric disorders as a neuroglial failure 2014
2014 Store-operated calcium entry in neuroglia 2014
2013 Calcium signalling and calcium channels: Evolution and general principles 2013
2013 Astrocyte glutamine synthetase: Pivotal in health and disease 2013
2013 A Caenorhabditis elegans locomotion phenotype caused by transgenic repeats of the hlh-17 promoter sequence 2013
2013 A possible role of astrocytes in contextual memory retrieval: An analysis obtained using a quantitative framework 2013
2013 Enhanced Ca2+-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model 2013
2013 Chemically functionalized single-walled carbon nanotube films modulate the morpho-functional and proliferative characteristics of astrocytes 2013
2013 Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: A potential role for reducing lipid accumulation 2013
2013 Astrogliopathology: Could nanotechnology restore aberrant calcium signalling and pathological astroglial remodelling? 2013
2013 Mitochondrial exchanger NCLX plays a major role in the intracellular Ca2+ signaling, gliotransmission, and proliferation of astrocytes 2013
2013 Astroglial amino acid-based transmitter receptors 2013
2013 Hyposmolality differentially and spatiotemporally modulates levels of glutamine synthetase and serine racemase in rat supraoptic nucleus 2013
2013 Astroglia in neurological diseases 2013
2013 Neuromodulation: Selected approaches and challenges 2013
2013 Method for the determination of trajectory angles of directional secretory vesicles in cultured astrocytes. 2013
2013 Sodium fluxes and astroglial function. 2013
2013 TRPC1-mediated Ca2+ and Na+ signalling in astroglia: Differential filtering of extracellular cations 2013
2012 Astrocytes revisited: Concise historic outlook on glutamate homeostasis and signaling 2012
2012 Homeostatic function of astrocytes: Ca2+ and Na+ signaling 2012
2012 Neurotransmitters and integration in neuronal-astroglial networks 2012
2012 Computational quest for understanding the role of astrocyte signaling in synaptic transmission and plasticity 2012
2012 Chemically functionalized water-soluble single-walled carbon nanotubes modulate morpho-functional characteristics of astrocytes 2012
2012 Fingolimod-A sphingosine-like molecule inhibits vesicle mobility and secretion in astrocytes 2012
2012 The astrocyte excitability brief: From receptors to gliotransmission 2012
2012 Sodium dynamics: Another key to astroglial excitability? 2012
2012 Neuroglia at the crossroads of homoeostasis, metabolism and signalling: Evolution of the concept 2012
2012 Low temperature and chemical rescue affect molecular proximity of ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC) 2012
2012 Calcium signalling in astroglia 2012
2012 Dissociated cell culture for testing effects of carbon nanotubes on neuronal growth 2012
2012 Glial cells in (patho)physiology 2012
2012 Cell culturing of Caenorhabditis elegans glial cells for the assessment of cytosolic Ca 2+ dynamics 2012
2012 Astroglial excitability and gliotransmission: An appraisal of Ca2+ as a signalling route 2012
2012 Bionanoelectronics: Getting close to the action 2012
2012 Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes 2012
2012 Ternary SNARE complexes in parallel versus anti-parallel orientation: Examination of their disassembly using single-molecule force spectroscopy 2012
2011 Single-walled carbon nanotubes chemically functionalized with polyethylene glycol promote tissue repair in a rat model of spinal cord injury 2011
2011 Single-molecule measurements of dissociation rates and energy landscapes of binary trans snare complexes in parallel versus antiparallel orientation 2011
2011 Temporal characteristics of vesicular fusion in astrocytes: Examination of synaptobrevin 2-laden vesicles at single vesicle resolution 2011
2011 Munc18-1 tuning of vesicle merger and fusion pore properties 2011
2011 Interaction of ASIC1 and ENaC subunits in human glioma cells and rat astrocytes 2011
2011 Ca2+ sources for the exocytotic release of glutamate from astrocytes 2011
2011 Ionotropic receptors in neuronal-astroglial signalling: What is the role of "excitable" molecules in non-excitable cells 2011
2011 Age-dependent spatial segregation of synaptobrevin 2-containing vesicles in astrocytes 2011
2011 Where the thoughts dwell: The physiology of neuronal-glial "diffuse neural net" 2011
2011 Immunophilin deficiency augments Ca2+-dependent glutamate release from mouse cortical astrocytes 2011
2011 Voltage-gated calcium channel types in cultured C. elegans CEPsh glial cells 2011
2010 Micropatterned substrates for studying astrocytes in culture 2010
2010 Regulated exocytosis in astrocytic signal integration 2010
2010 Recent advances in (patho)physiology of astroglia 2010
2010 SNAREs: Could they be the answer to an energy landscape riddle in exocytosis? 2010
2010 Gliotransmission: Exocytotic release from astrocytes 2010
2010 Carbon nanotubes in neuroscience. 2010
2009 Interactions between cultured neurons and carbon nanotubes: A nanoneuroscience vignette 2009
2009 Micropatterned substrates for studying astrocytes in culture 2009
2009 Single molecule measurements of interaction free energies between the proteins within binary and ternary SNARE complexes 2009
2009 Dual regulation of Ca21-dependent glutamate release from astrocytes: Vesicular glutamate transporters and cytosolic glutamate levels 2009
2009 Wiring neurons with carbon nanotubes 2009
2009 Single molecule measurements of mechanical interactions within ternary SNARE complexes and dynamics of their disassembly: SNAP25 vs. SNAP23 2009
2009 The trinity of Ca2+ sources for the exocytotic glutamate release from astrocytes 2009
2009 Astrocytic 'power-grid': Delivery upon neuronal demand. 2009
2009 Carbon nanotubes as substrates/scaffolds for neural cell growth 2009
2009 Conductive single-walled carbon nanotube substrates modulate neuronal growth 2009
2009 Dynamic imaging of cannabinoid receptor 1 vesicular trafficking in cultured astrocytes. 2009
2009 Energetics of (Dis)Assembly of the Ternary SNARE Complex. 2009
2009 Single molecule probing of SNARE proteins by atomic force microscopy 2009
2008 Micropit: A new cell culturing approach for characterization of solitary astrocytes and small networks of these glial cells 2008
2008 Water soluble single-walled carbon nanotubes inhibit stimulated endocytosis in neurons 2008
2008 Mitochondria modulate Ca2+-dependent glutamate release from rat cortical astrocytes 2008
2008 Molecular form follows function: (un)snaring the SNAREs 2008
2008 Single molecule probing of exocytotic protein interactions using force spectroscopy 2008
2008 Comparative energy measurements in single molecule interactions 2008
2008 Ca2+ entry through TRPC1 channels contributes to intracellular Ca2+ dynamics and consequent glutamate release from rat astrocytes 2008
2008 Models of astrocytic Ca2+ dynamics and epilepsy 2008
2008 Instrumentation: Carbon nanotubes on the brain 2008
2008 Mechanisms of glutamate release from astrocytes 2008
2007 Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons 2007
2007 Applications of carbon nanotubes in neurobiology 2007
2007 Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization 2007
2006 Vesicular transmitter release from astrocytes 2006
2006 Vesicular glutamate transporter expression in supraoptic neurones suggests a glutamatergic phenotype 2006
2006 Single molecule mechanical probing of the SNARE protein interactions 2006
2005 Chemically functionalized water soluble single-walled carbon nanotubes modulate neurite outgrowth 2005
2005 Detection of botulinum toxins: Micromechanical and fluorescence-based sensors 2005
2005 Polyethyleneimine functionalized single-walled carbon nanotubes as a substrate for neuronal growth 2005
2005 Applications of Carbon Nanotubes in Biotechnology and Biomedicine. 2005
2005 CCXCR1 is a receptor for cIL-8 (9E3/cCAF) and its N- and C-terminal peptides and is also activated by hIL-8 (CXCL8) 2005
2005 Nanofabricated carbon-based detector 2005
2004 Separation of individual neurons using dielectrophoretic alternative current fields 2004
2004 Ca2+-Dependent Glutamate Release Involves Two Classes of Endoplasmic Reticulum Ca2+ Stores in Astrocytes 2004
2004 Vesicular Glutamate Transporter-Dependent Glutamate Release from Astrocytes 2004
2004 Chemically functionalized carbon nanotubes as substrates for neuronal growth 2004
2004 Mechanisms of glutamate release from astrocytes: Gap junction "hemichannels", purinergic receptors and exocytotic release 2004
2004 The N- and C-terminal peptides of hIL8/CXCL8 are ligands for hCXCR1 and hCXCR2. 2004
2003 Fluorescence resonance energy transfer microscopy: Theory and instrumentation 2003
2003 Botulinum toxin type B micromechanosensor 2003
2003 Dopamine-induced oxidative stress in neurons with glutathione deficit: Implication for schizophrenia 2003
2002 Calcium signaling is required for ultrasound-stimulated aggrecan synthesis by rat chondrocytes 2002
2000 Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons 2000
2000 Imaging extracellular waves of glutamate during calcium signaling in cultured astrocytes 2000
2000 Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons 2000
1999 'Uncaging' using optical fibers to deliver UV light directly to the sample 1999
1999 Tripartite synapses: Glia, the unacknowledged partner 1999
1999 UV photolysis using a micromanipulated optical fiber to deliver UV energy directly to the sample 1999
1999 Activation of neurotransmitter release in hippocampal nerve terminals during recovery from intracellular acidification 1999
1999 Astrocyte-induced modulation of synaptic transmission 1999
1998 Calcium elevation in astrocytes causes an NMDA receptordependent increase in the frequency of miniature synaptic currents in cultured hippocampal neurons 1998
1998 Laser-induced native fluorescence (LINF) imaging of serotonin depletion in depolarized neurons 1998
1998 Glutamate-dependent astrocyte modulation of synaptic transmission between cultured hippocampal neurons 1998
1996 Membrane deformation of living glial cells using atomic force microscopy. 1996
1996 Atomic force microscopy study of the secretory granule lumen 1996
1996 Membrane deformation of living glial cells using atomic force microscopy 1996
1995 Expression of synaptobrevin II, cellubrevin and syntaxin but not SNAP-25 in cultured astrocytes 1995
1995 Neurotransmitter Imaging in Living Cells Based on Native Fluorescence Detection 1995
1995 α-Latrotoxin stimulates glutamate release from cortical astrocytes in cell culture 1995
1995 Dynamic imaging of purified individual synaptic vesicles 1995
1995 Neuroligand-evoked calcium-dependent release of excitatory amino acids from Schwann cells 1995
1994 Hippocampal synaptogenesis in cell culture: Developmental time course of synapse formation, calcium influx, and synaptic protein distribution 1994
1994 Hippocampal synaptogenesis in cell culture: developmental time course of synapse formation, calcium influx, and synaptic protein distribution. 1994
1994 Glutamate-mediated astrocyte-neuron signalling 1994
1993 Three-dimensional imaging of living neurons and glia with the atomic force microscope 1993
1989 Ketotifen and nasal steroid in hay fever pollinosis 1989
1989 [Ketotifen and nasal steroids in the therapy of pollinosis]. 1989
1989 Hypersensitivity to P. officinalis pollen: correlation of IgE with skin testing methods. 1989

Book

Year Title Altmetric
2014 Pathological potential of neuroglia: Possible new targets for medical intervention 2014
2009 Preface 2009

Chapter

Year Title Altmetric
2015 Astrocytes, Oligodendrocytes, and NG2 Glia: Structure and Function.  101-107. 2015
2015 Microglia: Structure and Function.  109-113. 2015
2014 General pathophysiology of neuroglia: Neurological and psychiatric disorders as gliopathies.  1-12. 2014
2014 Ionic signaling in physiology and pathophysiology of astroglia.  13-31. 2014
2014 Neurodegeneration and neuroglia: Emphasis on Astroglia in Alzheimer's disease.  265-291. 2014
2013 Astroglial Calcium Signaling and Calcium Waves.  51-68. 2013
2010 Carbon nanotubes as electrical interfaces with neurons.  325-340. 2010
2009 Mechanisms of transmitter release from astrocytes.  301-350. 2009
2007 Exocytic Release of Glutamate from Astrocytes: Comparison to Neurons.  329-365. 2007

Teaching Activities

  • DENT1255 - Neuroscience (Spring Term 2019) 2019
  • OBHS121 - Systems 1 Neuroscience (Spring Term 2019) 2019
  • NBL433 - Diseases of the Nervous System (Fall Term 2018) 2018
  • NBL633 - Diseases of the Nervous System (Fall Term 2018) 2018
  • DENT1255 - Neuroscience (Spring Term 2018) 2018
  • OBHS121 - Systems 1 Neuroscience (Spring Term 2018) 2018
  • NBL703 - Neurobiology Seminar Series (Spring Term 2018) 2018
  • NBL433 - Diseases of the Nervous System (Fall Term 2017) 2017
  • NBL703 - Neurobiology Seminar Series (Fall Term 2017) 2017
  • DENT1255 - Neuroscience (Spring Term 2017) 2017
  • OBHS121 - Systems 1 Neuroscience (Spring Term 2017) 2017
  • NBL433 - Diseases of the Nervous System (Spring Term 2017) 2017
  • NBL703 - Neurobiology Seminar Series (Spring Term 2017) 2017
  • PY433 - Diseases of Nervous System (Spring Term 2017) 2017
  • NBL703 - Neurobiology Seminar Series (Fall Term 2016) 2016
  • NBL433 - Diseases of the Nervous System (Spring Term 2016) 2016
  • NBL703 - Neurobiology Seminar Series (Spring Term 2016) 2016
  • PY433 - Diseases of Nervous System (Spring Term 2016) 2016
  • BME798 - Non-Dissertation Research (Fall Term 2015) 2015
  • NBL230 - Neuro: Brain Function/Dys (Fall Term 2015) 2015
  • NBL703 - Neurobiology Seminar Series (Fall Term 2015) 2015
  • BME799 - Dissertation Research (Summer Term 2015) 2015
  • GBS731 - Principles of Cell Neurosci (Summer Term 2015) 2015
  • BME799 - Dissertation Research (Spring Term 2015) 2015
  • NBL230 - Neuro: Brain Function/Dys (Spring Term 2015) 2015
  • NBL703 - Neurobiology Seminar Series (Spring Term 2015) 2015
  • BME799 - Dissertation Research (Fall Term 2014) 2014
  • GBS731 - Principles of Cell Neurosci (Fall Term 2014) 2014
  • NBL330 - Neuro: Brain Function & Dysfun (Fall Term 2014) 2014
  • NBL703 - Neurobiology Seminar Series (Fall Term 2014) 2014
  • BME798 - Non-Dissertation Research (Summer Term 2014) 2014
  • GBS731 - Principles of Cell Neuroscie (Summer Term 2014) 2014
  • BME798 - Non-Dissertation Research (Spring Term 2014) 2014
  • NBL703 - Neurobiology Seminar Series (Spring Term 2014) 2014
  • BME698 - Non-Thesis Research (Fall Term 2013) 2013
  • BME798 - Non-Dissertation Research (Fall Term 2013) 2013
  • GBS731 - Principles of Cell Neuroscie (Fall Term 2013) 2013
  • NBL703 - Neurobiology Seminar Series (Fall Term 2013) 2013
  • BME798 - Non-Dissertation Research (Summer Term 2013) 2013
  • GBS731 - Principles of Cell Neuroscie (Summer Term 2013) 2013
  • BME798 - Non-Dissertation Research (Spring Term 2013) 2013
  • NBL703 - Neurobiology Seminar Series (Spring Term 2013) 2013
  • NBL772 - Special Topics NeuroBio 2 (Spring Term 2013) 2013
  • BME699 - Masters Thesis Research (Fall Term 2012) 2012
  • GBS731 - Principles of Cell Neuroscie (Fall Term 2012) 2012
  • NBL703 - Neurobiology Seminar Series (Fall Term 2012) 2012
  • BME698 - Non-Thesis Research (Summer Term 2012) 2012
  • BME698 - Non-Thesis Research (Spring Term 2012) 2012
  • NBL703 - Neurobiology Seminar Series (Spring Term 2012) 2012
  • BME698 - Non-Thesis Research (Fall Term 2011) 2011
  • GBS731 - Principles of Cell Neuroscie (Fall Term 2011) 2011
  • NBL703 - Neurobiology Seminar Series (Fall Term 2011) 2011
  • BME698 - Non-Thesis Research (Summer Term 2011) 2011
  • NBL703 - Neurobiology Seminar Series (Spring Term 2011) 2011
  • NBL703 - Neurobiology Seminar Series (Fall Term 2010) 2010
  • CMB754 - CMB V Cell & Mole Neuroscience (Spring Term 2010) 2010
  • NBL703 - Neurobiology Seminar Series (Spring Term 2010) 2010
  • CMB754 - CELLULAR & MOLECULAR NEUROSCIENCE (Spring Term 2010) 2010
  • BME495 - Honors Research II (Fall Term 2009) 2009
  • NBL703 - Neurobiology Seminar Series (Fall Term 2009) 2009
  • CMB754 - CMB V Cell & Mole Neuroscience (Spring Term 2009) 2009
  • CMB754 - CMB V Cell & Mole Neuroscience (Spring Term 2008) 2008
  • NBL751 - Cellular/Molecular Neurobio (Spring Term 2008) 2008
  • Full Name

  • Vladimir Parpura