Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Spheroids of cardiomyocytes derived from human-induced pluripotent stem cells improve recovery from myocardial injury in miceJournal of Mid-Life Health.  315:H327-H339. 2018
2018 Large cardiac muscle patches engineered from human induced-pluripotent stem cell-derived cardiac cells improve recovery from myocardial infarction in swineMaterials Today: Proceedings.  137:1712-1730. 2018
2018 The stress kinase JNK regulates gap junction Cx43 gene expression and promotes atrial fibrillation in the aged heartJournal of Molecular and Cellular Cardiology.  114:105-115. 2018
2017 Electrophysiological Properties and Viability of Neonatal Rat Ventricular Myocyte Cultures with Inducible ChR2 ExpressionScientific Reports.  7. 2017
2017 Myocardial Tissue Engineering with Cells Derived from Human-Induced Pluripotent Stem Cells and a Native-Like, High-Resolution, 3-Dimensionally Printed ScaffoldBiologie Aujourd'hui.  120:1318-1325. 2017
2016 Biomimetic Cardiac Tissue Model Enables the Adaption of Human Induced Pluripotent Stem Cell Cardiomyocytes to Physiological Hemodynamic LoadsPan African Medical Journal.  88:9862-9868. 2016
2015 Voltage and calcium dual channel optical mapping of cultured HL-1 atrial myocyte monolayerJournal of Visualized Experiments2015
2014 The role of dye affinity in optical measurements of Cai2+ transients in cardiac muscleJournal of Mid-Life Health.  307. 2014
2013 C-Jun N-terminal kinase activation contributes to reduced connexin43 and development of atrial arrhythmiasJournal of Nonprofit and Public Sector Marketing.  97:589-597. 2013
2012 Intramural optical mapping of Vm and cai2+ during long-duration ventricular fibrillation in canine heartsJournal of Mid-Life Health.  302. 2012
2012 Ionic mechanism of shock-induced arrhythmias: Role of intracellular calciumHeart Rhythm.  9:96-104. 2012
2011 A new optrode design for intramural optical recordingsIEEE Transactions on Biomedical Engineering.  58:3130-3134. 2011
2011 Transmural heterogeneity and remodeling of ventricular excitation- contraction coupling in human heart failureMaterials Today: Proceedings.  123:1881-1890. 2011
2011 Transmural heterogeneity and remodeling of ventricular excitation- contraction coupling in human heart failureMaterials Today: Proceedings.  123:1881-1890. 2011
2010 Mechanisms of defibrillationAutomedica -New York-.  12:233-258. 2010
2009 Simultaneous Transmural Mapping of Voltage and Calcium in the Human HeartMaterials Today: Proceedings.  120:S667-S667. 2009
2009 Simultaneous Transmural Measurements of V-m and Ca-j(2+) During Rapid Pacing and Long-Duration Ventricular Fibrillation in Canine HeartsMaterials Today: Proceedings.  120:S689-S689. 2009
2009 Can mapping differentiate microreentry from a focus in the ventricle?Heart Rhythm.  6:1666-1669. 2009
2009 Transmural optical measurements of Vm dynamics during long-duration ventricular fibrillation in canine heartsHeart Rhythm.  6:796-802. 2009
2009 Optical mapping of impulse propagation in engineered cardiac tissueTissue Engineering: Parts A, B, and C.  15:851-860. 2009
2009 Change in conduction velocity due to fiber curvature in cultured neonatal rat ventricular myocytesIEEE Transactions on Biomedical Engineering.  56:855-861. 2009
2007 Optical measurements of intramural action potentials in isolated porcine hearts using optrodesHeart Rhythm.  4:1430-1436. 2007
2007 Optical mapping of V m and Cai2+ in a model of arrhythmias induced by local catecholamine application in patterned cell culturesPflügers Archiv European Journal of Physiology.  453:871-877. 2007
2007 Shock-induced changes of Cai2+ and Vm in myocyte cultures and computer model: Dependence on the timing of shock applicationJournal of Nonprofit and Public Sector Marketing.  73:101-110. 2007
2006 Role of intramural virtual electrodes in shock-induced activation of left ventricle: Optical measurements from the intact epicardial surfaceHeart Rhythm.  3:1063-1073. 2006
2005 Simultaneous optical imaging of membrane potential and intracellular calciumJournal of Electrocardiology.  38:107-112. 2005
2005 Simultaneous optical imaging of membrane potential and intracellular calciumJournal of Electrocardiology.  38. 2005
2005 Role of Microscopic Tissue Structure in Shock-Induced Activation Assessed by Optical Mapping in Myocyte CulturesJournal of Cardiovascular Electrophysiology.  16:991-1000. 2005
2005 Role of microscopic tissue structure in shock-induced activation assessed by optical mapping in myocyte culturesJournal of Cardiovascular Electrophysiology.  16:991-1000. 2005
2004 High-resolution optical mapping of intramural virtual electrodes in porcine left ventricular wallJournal of Nonprofit and Public Sector Marketing.  64:448-456. 2004
2004 Role of microscopic tissue structure in shock-induced activation assessed by optical mapping in myocyte culturesMaterials Today: Proceedings.  110:98-98. 2004
2004 Effects of electrical shocks on Cai2+ and V m in myocyte culturesBiologie Aujourd'hui.  94:1589-1597. 2004
2004 Intramural virtual electrodes in ventricular wall: Effects on epicardial polarizationsMaterials Today: Proceedings.  109:2349-2356. 2004
2004 Nonlinear Changes of Transmembrane Potential, during Electrical Shocks: Role of Membrane ElectroporationBiologie Aujourd'hui.  94:208-214. 2004
2003 Development of an Optrode for Intramural Multisite Optical Recordings of Vm in the HeartJournal of Cardiovascular Electrophysiology.  14:1196-1202. 2003
2003 Optical Mapping of Transmural Activation Induced by Electrical Shocks in Isolated Left Ventricular Wall Wedge PreparationsJournal of Cardiovascular Electrophysiology.  14:1215-1222. 2003
2003 The relationship of defibrillation and stimulation: Design implications for the optimum defibrillation waveformJournal of End User Computing.  5:245-246. 2003
2002 Modulation of triggered activity by uncoupling in the ischemic border: A model study with phase 1b-like conditionsJournal of Nonprofit and Public Sector Marketing.  56:381-392. 2002
2002 Optical mapping of V-m and Ca-i(2+) during arrhythmias induced by local perfusion of norepinephrine in cultured cell monolayersMaterials Today: Proceedings.  106:192-192. 2002
2002 Intramural virtual electrodes during defibrillation shocks in left ventricular wall assessed by optical mapping of membrane potentialMaterials Today: Proceedings.  106:1007-1014. 2002
2002 Optical mapping of arrhythmias induced by strong electrical shocks in myocyte culturesBiologie Aujourd'hui.  90:664-670. 2002
2001 Recent fibrillation studies: Attempts to wrest order from disorderBiologie Aujourd'hui.  89:1089-1091. 2001
2000 Shock-induced arrhythmias assessed using mapping of transmembrane potential and intracellular calcium in myocyte culturesMaterials Today: Proceedings.  102:341-341. 2000
2000 The role of calcium current in the nonlinear changes of transmembrane potential during defibrillation shocksMaterials Today: Proceedings.  102:340-340. 2000
2000 Nonlinear changes of transmembrane potential during defibrillation shocks: Role of Ca2+ currentBiologie Aujourd'hui.  87:453-459. 2000
2000 Mechanism of ventricular defibrillation: The role of tissue geometry in the changes in transmembrane potential in patterned myocyte culturesMaterials Today: Proceedings.  101:2438-2445. 2000
2000 Nonlinear changes of transmembrane potential caused by defibrillation shocks in strands of cultured myocytesJournal of Mid-Life Health.  278. 2000
2000 Nonlinear changes of transmembrane potential caused by defibrillation shocks in strands of cultured myocytes.Journal of Mid-Life Health.  278:H688-H697. 2000
2000 Effects of electrode-myocardial separation on cardiac stimulation in conductive solutionJournal of Cardiovascular Electrophysiology.  11:1132-1143. 2000
2000 Simultaneous imaging of transmembrane potential and intracellular calcium in myocyte culturesEuropean Heart Journal.  21:549-549. 2000
2000 Simultaneous optical mapping of transmembrane potential and intracellular calcium in myocyte culturesJournal of Cardiovascular Electrophysiology.  11:547-556. 2000
1999 Anisotropy of membrane polarization decreases when an electrode is separated from the myocardial surfaceMaterials Today: Proceedings.  100:786-786. 1999
1998 Effect of defibrillation shocks on transmembrane potential in strands of cultured myocytesMaterials Today: Proceedings.  98:52-52. 1998
1998 Activation of cardiac tissue by extracellular electrical shocks: Formation of 'secondary sources' at intercellular clefts in monolayers of cultured myocytesBiologie Aujourd'hui.  82:375-385. 1998
1997 Effects of biphasic shocks on the spatial distribution of the transmembrane potentialMaterials Today: Proceedings.  96:688-688. 1997
1997 Excitation of cardiac tissue by defibrillation shocks: Role of microscopic tissue geometryMaterials Today: Proceedings.  96:683-683. 1997
1997 Molecular and cellular aspects of re-entrant arrhythmiasNahrung..  92:111-119. 1997
1997 Gap junctional uncoupling facilitates conduction in discontinuous cardiac tissue structuresPflügers Archiv European Journal of Physiology.  433:9-9. 1997
1997 Paradoxical improvement of impulse conduction in cardiac tissue by partial cellular uncouplingScience.  275:841-844. 1997
1997 Partial cellular uncoupling reverses unidirectional conduction block across abrupt expansions of cardiac tissue.Journal of Human Lactation.  72:WAMD6-WAMD6. 1997
1997 Role of wavefront curvature in propagation of cardiac impulseJournal of Nonprofit and Public Sector Marketing.  33:258-271. 1997
1996 Physiology and pathophysiology of cardiac impulse conductionZeitschrift für Kardiologie.  85:25-33. 1996
1996 Anisotropic Activation Spread in Heart Cell Monolayers Assessed by High-Resolution Optical Mapping: Role of Tissue DiscontinuitiesBiologie Aujourd'hui.  79:115-127. 1996
1996 Functional and structural assessment of intercellular communication: Increased conduction velocity and enhanced connexin expression in dibutyryl cAMP-treated cultured cardiac myocytesBiologie Aujourd'hui.  79:174-183. 1996
1996 Spatial changes in transmembrane potential during extracellular electrical shocks in cultured monolayers of neonatal rat ventricular myocytesBiologie Aujourd'hui.  79:676-690. 1996
1995 DIRECT LINK BETWEEN GAP JUNCTION REMODELING AND CHANGES IN CONDUCTION IN CULTURED MYOCYTESMaterials Today: Proceedings.  92:189-189. 1995
1995 RELATION BETWEEN GAP JUNCTION DISTRIBUTION AND ANISOTROPIC ACTIVATION SPREAD IN CULTURED MONOLAYERS OF NEONATAL RAT MYOCYTESMaterials Today: Proceedings.  92:188-188. 1995
1995 Block of impulse propagation at an abrupt tissue expansion: evaluation of the critical strand diameter in 2- and 3-dimensional computer modelsJournal of Nonprofit and Public Sector Marketing.  30:449-459. 1995
1995 Block of impulse propagation at an abrupt tissue expansion: Evaluation of the critical strand diameter in 2- and 3-dimensional computer modelsJournal of Nonprofit and Public Sector Marketing.  30:449-459. 1995
1995 Cardiac tissue geometry as a determinant of unidirectional conduction block: Assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer modelJournal of Nonprofit and Public Sector Marketing.  29:697-707. 1995
1994 2-DIMENSIONAL HIGH-RESOLUTION OPTICAL MAPPING OF ANISOTROPIC IMPULSE CONDUCTION IN NEONATAL RAT-HEART CEL MONOLAYERSMaterials Today: Proceedings.  90:40-40. 1994
1994 CONDUCTION-VELOCITY AND SHAPE OF ACTION-POTENTIAL UPSTROKE IN A COMPUTER-MODEL OF AN ANISOTROPIC HEART CELL MONOLAYERMaterials Today: Proceedings.  90:411-411. 1994
1994 Cardiac tissue geometry as a determinant of unidirectional conduction block: Assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer modelJournal of Nonprofit and Public Sector Marketing.  28:697-707. 1994
1994 Anisotropic conduction in monolayers of neonatal rat heart cells cultured on collagen substrateBiologie Aujourd'hui.  75:591-595. 1994
1993 TISSUE GEOMETRY AS A DETERMINANT OF UNIDIRECTIONAL CONDUCTION BLOCK - ASSESSMENT OF MICROSCOPIC EXCITATION SPREAD BY OPTICAL MAPPING IN PATTERNED MYOCYTE CULTURESMaterials Today: Proceedings.  88:623-623. 1993
1993 Microscopic conduction in cultured strands of neonatal rat heart cells measured with voltage-sensitive dyesBiologie Aujourd'hui.  73:914-925. 1993
1992 DISCONTINUOUS IMPULSE PROPAGATION AT A CELLULAR-LEVEL IN CULTURED STRANDS OF NEONATAL RAT-HEART CELLSMaterials Today: Proceedings.  86:752-752. 1992
1992 OPTICAL VERSUS ELECTRICAL DETECTION OF RAPID MEMBRANE-POTENTIAL CHANGES IN CULTURED NEONATAL RAT-HEART CELLSMaterials Today: Proceedings.  86:820-820. 1992
1992 Shift and Termination of Functional Reentry in Isolated Ventricular Preparations with Quinidine‐Induced Inhomogeneity in Refractory PeriodJournal of Cardiovascular Electrophysiology.  3:255-265. 1992
1991 [Isolated right ventricle after coronary perfusion as a model for the study of ischemic and reperfusion-induced arrhythmia in rats].Kardiologiia.  31:58-61. 1991
1991 Stability of vortex rotation in an excitable cellular mediumPhysica D: Nonlinear Phenomena.  49:75-81. 1991
1991 Isolated coronary perfused rat right ventricle as a model for examination of ischemic and perfusion arrhythmiasKardiologiia.  31:58-61. 1991
1991 Vagally induced depression of impulse propagation as a cause of atrial tachycardiaJournal of Molecular and Cellular Cardiology.  23:3-9. 1991
1990 Transition from circular to linear rotation of a vortex in an excitable cellular mediumPhysics Letters A.  151:157-161. 1990
1990 Drift of a vortex in the myocardiumБиофизика.  35:489-494. 1990
1990 [Effects of lidocaine on intramural circulation in isolated rabbit heart ventricle preparations].Kardiologiia.  30:93-96. 1990
1990 Drift of vortex in myocardiumБиофизика.  35:478-482. 1990
1990 Effects of lidocaine on intramural reentry in isolated rabbit ventricular specimensKardiologiia.  30:93-96. 1990
1989 Study of spontaneous acetylcholine-dependent tachyarrhythmias using isolated specimens of the right canine atrium by bilateral mapping of the spread of excitationKardiologiia.  29:80-85. 1989
1989 Vagally induced block and delayed conduction as a mechanism for circus movement tachycardia in frog atriaBiologie Aujourd'hui.  64:213-226. 1989
1988 The mechanism of the development of atrial tachyarrhythmia after stimulation of the vagus nerveKardiologiia.  28:79-84. 1988
1987 3-dimensional reentry in paroxysmal ventricular tachycardias: the results of electrophysiological mappingKardiologiia.  27:75-79. 1987
1986 Effect of lidocaine on the leading cycle and focal source of arrhythmia in isolated specimens of rabbit cardiac tissue during hypothermiaKardiologiia.  26:83-86. 1986
1986 Characteristics of the restoration of the electromechanical properties of the isolated myocardium following fluorocarbon cardioplegiaVestnik Akademii meditsinskikh nauk SSSR.  43-49. 1986
1985 [Cold-induced arrhythmias in the isolated rabbit atrium studied by mapping].Kardiologiia.  25:93-97. 1985
1985 A mapping study of hyperthermic arrhythmias in the isolated rabbit atriumKardiologiia.  25:93-97. 1985

Chapter

Year Title Altmetric
2013 Mechanisms of defibrillation.  199-215. 2013
2009 The role of microscopic tissue structure in defibrillation.  255-281. 2009
2005 Recording action potentials using voltage-sensitive dyes.  233-255. 2005
2004 Cellular Mechanisms of Defibrillation.  407-416. 2004

Teaching Activities

  • BME210 - Engineering in Biology (Spring Term 2019) 2019
  • BME210 - Engineering in Biology (Spring Term 2018) 2018
  • BME210 - Engineering in Biology (Spring Term 2017) 2017
  • BME210 - Engineering in Biology (Spring Term 2016) 2016
  • BME798 - Non-Dissertation Research (Spring Term 2016) 2016
  • BME798 - Non-Dissertation Research (Fall Term 2015) 2015
  • BME210 - Engineering in Biology (Spring Term 2015) 2015
  • BME210 - Engineering in Biology (Fall Term 2014) 2014
  • BME495 - Honors Research II (Fall Term 2014) 2014
  • BME210 - Engineering in Biology (Spring Term 2014) 2014
  • BME491 - Individual Study in (Area) (Spring Term 2014) 2014
  • BME494 - Honors Research I (Spring Term 2014) 2014
  • BME698 - Non-Thesis Research (Spring Term 2014) 2014
  • BME798 - Non-Dissertation Research (Spring Term 2014) 2014
  • BME698 - Non-Thesis Research (Fall Term 2013) 2013
  • BME798 - Non-Dissertation Research (Fall Term 2013) 2013
  • BME210 - Engineering Biology (Spring Term 2013) 2013
  • BME210 - Engineering Biology (Spring Term 2012) 2012
  • BME699 - Masters Thesis Research (Summer Term 2011) 2011
  • BME210 - Engineering Biology (Spring Term 2011) 2011
  • BME698 - Non-Thesis Research (Spring Term 2011) 2011
  • BME494 - Honors Research I (Fall Term 2010) 2010
  • BME698 - Non-Thesis Research (Fall Term 2010) 2010
  • BME698 - Non-Thesis Research (Summer Term 2010) 2010
  • BME210 - Engineering Biology (Spring Term 2010) 2010
  • BME698 - Non-Thesis Research (Spring Term 2010) 2010
  • BME698 - Non-Thesis Research (Fall Term 2009) 2009
  • EGR150 - Computer Meth in Engineering (Fall Term 2009) 2009
  • BME210 - Engineering Biology (Spring Term 2009) 2009
  • BME210 - Engineering Biology (Spring Term 2008) 2008
  • Education And Training

    Full Name

  • Vladimir Fast