Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Two Glycoconjugates of Dopamine, IPX-750 and IPX-760, Attenuate α-Synuclein OligomerizationJ Nanomed Nanosci2018
2015 Use of siRNA molecular beacons to detect and attenuate mycobacterial infection in macrophages.World Journal of Experimental Medicine.  5:164-181. 2015
2014 (483) Transdermal pain creams attenuate pain in military (TRICARE) chronic pain sufferersJournal of Pain.  15:S96-S96. 2014
2014 (486) Customized transdermal pain cream reduced pain and improved quality of lifeJournal of Pain.  15:S97-S97. 2014
2014 A short interfering rna molecular beacon for the attenuation of mycobacterial infectionAmerican Journal of Biochemistry and Biotechnology.  10:40-49. 2014
2014 The Na + /Ca 2+ exchanger: A possible link between oxidative stress and endogenous ouabain in hypertensionJournal of Pediatric Biochemistry.  4:127-137. 2014
2014 The Na+/Ca2+exchanger: A possible link between oxidative stress and endogenous ouabain in hypertensionJournal of Pediatric Biochemistry.  4:127-137. 2014
2014 Transdermal Pain Creams Attenuate Pain, Improve Quality of Life, and Reduce Oral Pain Medication Use in a Population of 65 Years Old and Older Chronic Pain SufferersThe Journal of Pain.  15. 2014
2014 Transdermal pain creams attenuate pain in military (TRICARE) chronic pain sufferersThe Journal of Pain.  15. 2014
2014 Transdermal pain creams reduced pain and improved quality of life.The Journal of Pain.  15. 2014
2012 IPX-750, A Dopamine Gluconamine That Binds D1/D5 Receptors and Has Anti-Parkinsonian Effects in Three Animal Models, is Transported across the Blood Brain BarrierJournal of Biotechnology and Biomaterials.  02. 2012
2012 The Tripeptide, GHK, Induces Programmed Cell Death in SH-SY5Y Neuroblastoma CellsJournal of Biotechnology and Biomaterials.  02. 2012
2010 The Na + /Ca 2+ exchanger mediates the effects of oxidative stress in hypertensionCurrent Hypertension Reviews.  6:260-265. 2010
2007 ICX-550 induces programmed cell death in malignant cellsEthnicity and Disease.  17. 2007
2007 ICX-550 induces programmed cell death in malignant cellsEthnicity and Disease.  17:S35-S36. 2007
2005 Regulation of macula densa nitric oxide synthaseFederation proceedings.  19:A1140-A1140. 2005
2005 The Na+/Ca2+ exchanger: A potential target for homocysteine in hypertensionFederation proceedings.  19:A575-A575. 2005
2005 Amyloid beta peptide 1-40 stimulates the Na+/Ca2+ exchange activity of SNCXCurrent Neurovascular Research.  2:3-12. 2005
2004 Homocysteine attenuates the activity of RNCX, a salt resistant exchangerCell regulation.  15:189A-189A. 2004
2004 Homocysteine attenuates the activity of SNCX, a salt sensitive Na+/Ca2+ exchangerCell regulation.  15:189A-189A. 2004
2004 Regulation of Mesangial Cell Na+/Ca2+ Exchanger IsoformsJournal of Cellular Physiology.  199:181-193. 2004
2004 Altered Na+/Ca2+ exchange activity in a mouse cell model of polycystic kidney diseaseFederation proceedings.  18:A700-A700. 2004
2004 Regulation of renal Na+/Ca2+ exchanger isoformsJ Cell Physiol.  199:181-193. 2004
2003 Immunolocalization of a microsomal prostaglandin E synthase in rabbit kidneyAJP - Renal Physiology.  285. 2003
2003 Immunolocalization of a microsomal prostaglandin E synthase in rabbit kidney.AJP - Renal Physiology.  285:F558-F564. 2003
2003 Na+/Ca2+ exchanger: Target for oxidative stress in salt-sensitive hypertensionHypertension.  42:363-368. 2003
2003 Impaired ability of the Na+/Ca2+ exchanger from the Dahl/Rapp salt-sensitive rat to regulate cytosolic calcium.AJP - Renal Physiology.  284:F1023-F1031. 2003
2003 Impaired ability of the Na+/Ca2+exchanger from the Dahl/Rapp salt-sensitive rat to regulate cytosolic calciumAJP - Renal Physiology.  284. 2003
2002 Role of P1P(2) and PIP3 in the regulation of ENaC by purinergic and corticoid receptors.Journal of the American Society of Nephrology.  13:277A-277A. 2002
2002 The Na+/Ca2+ exchanger in salt sensitive hypertensionHypertension.  40:416-416. 2002
2002 Incomplete inactivation of voltage-dependent K+ channels in human B lymphoma cellsJournal of Membrane Biology.  188:97-105. 2002
2002 Oxidative stress attenuates the exchange activity of a Sprague Dawley mesangial cell Na+/Ca2(+) exchanger isoformFederation proceedings.  16:A431-A431. 2002
2002 Regulation of a Sprague Dawley mesangial cell Na+/Ca2+ exchanger isoform by intracellular pH, and protein kinases A and GFederation proceedings.  16:A474-A474. 2002
2002 Dysregulation of [Ca2+]iin OK-PTH cells expressing a mesangial cell Na+/Ca2+exchanger isoform from Dahl/Rapp salt-sensitive ratsAnnals of the New York Academy of Sciences.  976:338-341. 2002
2002 Enhanced susceptibility of a Na+/Ca2+exchanger isoform from mesangial cells of salt-sensitive Dahl/Rapp rats to oxidative stress inactivationAnnals of the New York Academy of Sciences.  976:342-344. 2002
2001 Na+: Ca2+ exchange activity in SH-SY5Y human neuroblastoma cellsFederation proceedings.  15:A1117-A1117. 2001
2001 Cloning and functional analysis of a Na+: Ca2+exchanger isoform from mesangial cells of Sprague Dawley ratsFederation proceedings.  15:A145-A145. 2001
2000 Cloning of mesangial cell Na(+)/Ca(2+) exchangers from Dahl/Rapp salt-sensitive/resistant rats.AJP - Renal Physiology.  279:F177-F184. 2000
2000 Cloning of mesangial cell Na+/Ca2+ exchangers from Dahl/Rapp salt-sensitive/resistant ratsAJP - Renal Physiology.  279. 2000
2000 Renal sodium/calcium exchange; A vasodilator that is defective in salt-sensitive hypertensionActa Physiologica Scandinavica.  168:209-214. 2000
2000 Dysregulation of the renal Na+/Ca2+ exchanger in salt sensitive hypertensionThe Genetics of Experimental and Human Hypertension Symposium.  44-45. 2000
1999 Altered protein kinase C activation of Na+/Ca2+ exchange in mesangial cells from salt-sensitive ratsAmerican Journal of Physiology.  276. 1999
1999 Differential sensitivities of Na+: Ca2+ exchanger isoforms. To oxidative stressCell regulation.  10:48A-48A. 1999
1999 Altered protein kinase C activation of Na+/Ca2+ exchange in mesangial cells from salt-sensitive ratsAJP - Renal Physiology.  276:F574-F580. 1999
1999 Altered protein kinase C activation of Na+/Ca2+ exchange in mesangial cells from salt-sensitive rats.American Journal of Physiology.  276:F574-F580. 1999
1999 Altered protein kinase C activation of Na+/Ca2+ exchange in mesangial cells from salt-sensitive ratsAJP - Renal Physiology.  276. 1999
1999 Renal arteriolar Na+/Ca2+ exchange in salt-sensitive hypertensionAJP - Renal Physiology.  276:F567-F573. 1999
1999 Renal arteriolar Na+/Ca2+ exchange in salt-sensitive hypertension.American Journal of Physiology.  276:F567-F573. 1999
1999 Differential regulation of the sodium/calcium exchanger by protein kinase C in mesangial cells of salt sensitive and salt resistant Dahl ratsFederation proceedings.  13:A116-A116. 1999
1999 Renal arteriolar Na+/Ca2+ exchange in salt-sensitive hypertensionAJP - Renal Physiology.  276. 1999
1998 Regulation of the Na+:Ca2+ exchanger by angiotensin II-PKC in mesangial cells from salt Resistant (R) and salt Sensitive (S) ratsFederation proceedings.  12. 1998
1998 Human ENaC expressed in xenopus oocytes is activated by cyclic AMP.Federation proceedings.  12:A372-A372. 1998
1997 Differential activation of the Na:Ca exchanger by PMA in mesangial cells of R and S rats.Cell regulation.  8:487-487. 1997
1997 Differential activation of the Na:Ca exchanger by PMA in mesangial cells from salt sensitive hypertensive rats.Journal of the American Society of Nephrology.  8:A1422-A1422. 1997
1997 Lithium attenuates nerve growth factor-induced activation of AP-1 DNA binding activity in PC12 cellsNeuropsychopharmacology.  17:12-17. 1997
1997 Dexamethasone attenuates NF-κB DNA binding activity without inducing IκB levels in rat brain in vivoBrain Research.  45:83-89. 1997
1996 A possible mechanism by which glucocorticoids effect neuronal degeneration in aging and Alzheimer's disease.Cell regulation.  7:1032-1032. 1996
1996 Prolonged c-jun expression in irradiated ataxia telangiectasia fibroblastsInternational Journal of Radiation Oncology - Biology - Physics.  36:355-360. 1996
1995 GLUCOCORTICOIDS ATTENUATE AP-1 AND NFKB DNA-BINDING ACTIVITIES IN RAT-BRAIN - IMPLICATION OF GLUCOCORTICOIDS IN NEURONAL DEGENERATIONCell regulation.  6:1397-1397. 1995
1995 Inhibition of NFkB DNA binding activity by glucocorticoids in rat brainNeuroscience Letters.  198:41-44. 1995
1995 Direct identification of recombinant clones in Escherichia coli utilizing supercoiled DNABioTechniques.  18. 1995
1995 Diurnal variation in kainate-induced AP-1 activation in rat brain: influence of glucocorticoidsBrain Research.  28:193-200. 1995
1995 Lithium modulates neuronal signal transduction systems in Mechanism of Antibipolar TreatmentsLithium1995
1994 A peptide encoding the c-Jun δ domain inhibits the activity of a c-Jun amino-terminal protein kinaseJournal of Biological Chemistry.  269:11186-11191. 1994
1994 Dexamethasone attenuates kainate-induced AP-1 activation in rat brainBrain Research.  24:275-282. 1994
1993 REGULATION OF C-JUN PHOSPHORYLATION IN HEMATOPOIETIC-CELLSJournal of Cellular Biochemistry.  183-183. 1993
1993 Multiple signal transduction pathways mediate c-Jun protein phosphorylation.Cell Growth and Differentiation.  4:377-385. 1993
1992 Upstream regions of the c-jun promoter regulate phorbol ester-induced transcription in U937 leukemic cellsNucleic Acids Research.  20:897-902. 1992
1992 Induction of differentiation and c‐jun expression in human leukemic cells by okadaic acid, an inhibitor of protein phosphatasesJournal of Cellular Physiology.  151:415-426. 1992
1991 Expression of the human neutrophil elastase gene: Positive and negative transcriptional elements in the 5′ flanking regionBiochemical and Biophysical Research Communications.  181:1462-1468. 1991
1991 Regulation of c-jun expression and AP-1 enhancer activity by granulocyte-macrophage colony-stimulating factorJournal of Biological Chemistry.  266:5670-5675. 1991

Education And Training

  • Doctor of Philosophy in Biochemistry, Kansas State University 1989
  • Master of Sciences or Mathematics in Biology, Western Kentucky University 1983
  • Bachelor of Science or Mathematics in Chemistry, Western Kentucky University 1981
  • Full Name

  • M. Tino Unlap