Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Immunotherapy of Guillain-Barré syndromeHuman Vaccines and Immunotherapeutics.  14:2568-2579. 2018
2018 Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathyTissue Barriers.  6:1-22. 2018
2017 The Human Blood-Nerve Barrier TranscriptomeScientific Reports.  7. 2017
2017 Fibronectin connecting segment-1 peptide inhibits pathogenic leukocyte trafficking and inflammatory demyelination in experimental models of chronic inflammatory demyelinating polyradiculoneuropathyExperimental Neurology.  292:35-45. 2017
2017 A novel method for measuring hydraulic conductivity at the human blood-nerve barrier in vitroMicrovascular Research.  109:1-6. 2017
2016 "Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health WorkshopJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  5. 2016
2016 The pathogenic relevance of αM-integrin in Guillain–Barré syndromeActa Neuropathologica.  132:739-752. 2016
2016 Modeling leukocyte trafficking at the human blood-nerve barrier in vitro and in vivo geared towards targeted molecular therapies for peripheral neuroinflammationJournal of Neuroinflammation.  13. 2016
2015 Inflammatory neuropathies: pathology, molecular markers and targets for specific therapeutic interventionActa Neuropathologica.  130:445-468. 2015
2015 Osteoblasts Have a Neural Origin in Heterotopic OssificationClinical Orthopaedics and Related Research.  473:2790-2806. 2015
2014 VIP-expressing dendritic cells protect against spontaneous autoimmune peripheral polyneuropathy.Molecular Therapy.  22:1353-1363. 2014
2014 CCR2 Gene deletion and pharmacologic blockade ameliorate a severe murine experimental autoimmune neuritis model of Guillain-Barré syndromePLoS ONE.  9. 2014
2014 VIP-expressing dendritic cells protect against spontaneous autoimmune peripheral polyneuropathyMolecular Therapy.  22:1353-1363. 2014
2013 A man with small vessel vasculitis presenting with brachial diplegia, multiple cranial mononeuropathies and severe orthostatic hypotension in diabetes mellitus: A case reportJournal of Medical Case Reports.  7. 2013
2013 A case of severe chronic progressive axonal polyradiculoneuropathy temporally associated with anti-CV2/CRMP5 antibodiesJournal of Clinical Neuromuscular Disease.  15:13-18. 2013
2013 The role of chemokines in guillain-barré syndromeMuscle and Nerve.  48:320-330. 2013
2013 VEGF-A165 Potently induces human blood-nerve barrier endothelial cell proliferation, angiogenesis, and wound healing in vitroCellular and Molecular Neurobiology.  33:789-801. 2013
2013 An immortalized human blood-nerve barrier endothelial cell line for in vitro permeability studiesCellular and Molecular Neurobiology.  33:175-186. 2013
2013 Chemokine-dependent signaling pathways in the peripheral nervous systemMethods in Molecular Biology.  1013:17-30. 2013
2013 The molecular and biophysical characterization of the human blood-nerve barrier: Current conceptsJournal of Vascular Research.  50:289-303. 2013
2012 Translational strategies in peripheral neuroinflammation and neurovascular repairTranslational Neuroscience.  3:373-383. 2012
2012 α Mβ 2-integrin-intercellular adhesion molecule-1 interactions drive the flow-dependent trafficking of Guillain-Barré syndrome patient derived mononuclear leukocytes at the blood-nerve barrier in vitroJournal of Cellular Physiology.  227:3857-3875. 2012
2012 Subacute brachial diplegia associated with west nile virus myelitisMuscle and Nerve.  45:900-904. 2012
2012 GDNF restores human blood-nerve barrier function via RET tyrosine kinase-mediated cytoskeletal reorganizationMicrovascular Research.  83:298-310. 2012
2012 Behavioral, electrophysiological, and histopathological characterization of a severe murine chronic demyelinating polyneuritis modelJournal of the Peripheral Nervous System.  17:53-61. 2012
2012 Transient brown adipocyte-like cells derive from peripheral nerve progenitors in response to bone morphogenetic protein 2Stem Cells Translational Medicine.  1:874-885. 2012
2011 Chemokine receptors as specific anti-inflammatory targets in peripheral nervesEndocrine, Metabolic and Immune Disorders - Drug Targets.  11:141-153. 2011
2010 Dorsal caudal tail and sciatic motor nerve conduction studies in adult mice: Technical aspects and normative dataMuscle and Nerve.  41:850-856. 2010
2010 Clinical, electrophysiological and pathologic correlations in a severe murine experimental autoimmune neuritis model of Guillain-Barré syndromeJournal of Neuroimmunology.  219:54-63. 2010
2010 Development and characterization of a novel human in vitro blood-nerve barrier model using primary endoneurial endothelial cellsJournal of Neuropathology and Experimental Neurology.  69:82-97. 2010
2010 Selective expression and cellular localization of pro-inflammatory chemokine ligand/receptor pairs in the sciatic nerves of a severe murine experimental autoimmune neuritis model of Guillain-Barré syndromeNeuropathology and Applied Neurobiology.  36:388-398. 2010
2009 Dynamic properties of eye movements in mitochondrial chronic progressive external ophthalmoplegiaEye.  23:382-388. 2009
2008 Interferon-α-2b/ribavirin-induced vestibulocochlear toxicity with dysautonomia in a chronic hepatitis C patientEuropean Journal of Gastroenterology and Hepatology.  20:1110-1114. 2008
2008 Predictors of Clinical Outcome and Mortality in Vertebrobasilar Dolichoectasia Diagnosed by Magnetic Resonance AngiographyJournal of Stroke and Cerebrovascular Diseases.  17:388-393. 2008
2008 Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migrationClinical and Developmental Immunology.  2008. 2008
2007 Chronic inflammatory demyelinating polyradiculoneuropathy presenting as cauda equina syndrome in a diabeticJournal of the Neurological Sciences.  260:267-270. 2007
2007 Inflammatory cell migration into the central nervous system: A few new twists on an old taleBrain Pathology.  17:243-250. 2007
2007 "Doing the locomotion" with the multistep paradigmBlood.  109:1342-1343. 2007
2006 CCR5 expression on monocytes and T cells: Modulation by transmigration across the blood-brain barrier in vitroCellular Immunology.  243:19-29. 2006
2006 Determinants of CCL5-driven mononuclear cell migration across the blood-brain barrier. Implications for therapeutically modulating neuroinflammationJournal of Neuroimmunology.  179:132-144. 2006
2006 Electrodiagnostic criteria for carpal tunnel syndrome in axonal polyneuropathyMuscle and Nerve.  33:747-752. 2006
2006 Modulating CCR2 and CCL2 at the blood-brain barrier: Relevance for multiple sclerosis pathogenesisBrain.  129:212-223. 2006
2006 The expression and function of chemokines involved in CNS inflammationTrends in Pharmacological Sciences.  27:48-55. 2006
2005 Adult polyglucosan body disease: A case report of a manifesting heterozygoteMuscle and Nerve.  32:675-681. 2005
2005 Complete innervation of extensor digitorum brevis by accessory peroneal nerveNeuromuscular Disorders.  15:562-564. 2005
2005 Intracranial arterial dolichoectasia is associated with enlarged descending thoracic aorta [1] (multiple letters)Neurology.  65:1681-1682. 2005
2004 Clinical and radiological features of symptomatic cerebral perfusion failure due to carotid artery occlusion surgically corrected by extracranial-intracranial bypass surgery [2]Journal of Neurology.  251:613-616. 2004
2004 Asymptomatic middle cerebral artery stenosis diagnosed by magnetic resonance angiography.Neuroradiology.  46:49-53. 2004
2004 Transverse myelitis associated with Acinetobacter baumanii intrathecal pump catheter-related infection. Where was the source of the infection? [1] (multiple letters)Regional anesthesia.  29:503-504. 2004
2004 Vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography and risk of stroke and death: A cohort studyJournal of Neurology, Neurosurgery and Psychiatry.  75:22-26. 2004
2003 Adverse Reactions to Mirtazapine are Unlikely to be Serotonin Toxicity [1]Clinical Neuropharmacology.  26:287-290. 2003
2003 Mirtazapine-induced serotonin syndromeClinical Neuropharmacology.  26:54-57. 2003
2003 Ketamine for refractory status epilepticus : A case of possible ketamine-induced neurotoxicityEpilepsy and Behavior.  4:70-75. 2003
2003 Transverse myelitis associated with Acinetobacter baumanii intrathecal pump catheter-related infectionRegional anesthesia.  28:470-474. 2003
2002 Rectus sheath hematoma complicating percutaneous endoscopic gastrostomySurgical Laparoscopy and Endoscopy.  12:430-432. 2002
2002 Cervicomedullary junction compression caused by vertebral artery dolichoectasia and requiring surgical treatmentJournal of Neurosurgery.  96:140-143. 2002
2002 Otalgia as the sole presenting manifestation of subdural hematomaAmerican Journal of Otolaryngology.  23:177-180. 2002
2002 Recurrent transient ischemic attacks as the initial presenting manifestation of type A aortic dissectionAnnals of Vascular Surgery.  16:676-678. 2002
2001 The preferential involvement of extraocular muscles by myasthenia gravisNeuro-Ophthalmology.  25:219-228. 2001
2001 Amaurosis fugax associated with phencyclidine inhalationEuropean Neurology.  46:98-99. 2001
2001 Acute motor-sensory axonal neuropathy associated with active systemic lupus erythematosus and anticardiolipin antibodiesJCR: Journal of Clinical Rheumatology.  7:326-331. 2001

Principal Investigator On

  • Topiramate as a Disease Altering Therapy for Cryptogenic Sensory Peripheral Neuropalhy (CSPN)  awarded by MASSACHUSETTS GENERAL HOSPITAL 2017 - 2023
  • A Phase ll of Rituximab in Myasthenia Gravis (NN 103)  awarded by MASSACHUSETTS GENERAL HOSPITAL 2015 - 2023
  • UAB MDA CARE CENTER  awarded by Muscular Dystrophy Association 2017 - 2019
  • Private Grant  awarded by Genzyme Corporation 2017 - 2019
  • Private Grant  awarded by CSL BEHRING, LLC 2014 - 2019
  • Characterization of Agrin/LRP4 Antibody-Positive Myastenia Gravis  awarded by GEORGIA REGENTS UNIVERSITY (AUGUSTA) 2018 - 2019
  • Private Grant  awarded by CATALYST PHARMACEUTICAL PARTNERS, INC. 2016 - 2019
  • Vascular Biology of the Human Blood-Nerve Barrier  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2018
  • Characterization of Agrin/LRP4 Antibody-Positive Myasthenia Gravis  awarded by GEORGIA REGENTS UNIVERSITY (AUGUSTA) 2015 - 2017
  • Private Grant  awarded by CATALYST PHARMACEUTICAL PARTNERS, INC. 2015 - 2017
  • Private Grant  awarded by CSL BEHRING, LLC 2013 - 2017
  • MDA Sponsored Clinic Grant  awarded by Muscular Dystrophy Association 2014 - 2016
  • Alpha M Beta 2 Integrin Blockade for Acute Inflammatory Neuropathies  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2015
  • Fibronectin Peptide Antagonism for Chronic Inflammatory Neuropathies  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2014
  • Full Name

  • Eroboghene Ubogu