Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Immunotherapy of Guillain-Barré syndrome.Human Vaccines and Immunotherapeutics.  1-12. 2018
2018 Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathy.Tissue Barriers.  6:1-22. 2018
2017 The Human Blood-Nerve Barrier Transcriptome.Scientific Reports.  7:17477. 2017
2017 Fibronectin connecting segment-1 peptide inhibits pathogenic leukocyte trafficking and inflammatory demyelination in experimental models of chronic inflammatory demyelinating polyradiculoneuropathy.Experimental Neurology.  292:35-45. 2017
2017 A novel method for measuring hydraulic conductivity at the human blood-nerve barrier in vitro.Microvascular Research.  109:1-6. 2017
2016 "Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health Workshop.Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  5. 2016
2016 The pathogenic relevance of αM-integrin in Guillain-Barré syndrome.Acta Neuropathologica.  132:739-752. 2016
2016 Modeling leukocyte trafficking at the human blood-nerve barrier in vitro and in vivo geared towards targeted molecular therapies for peripheral neuroinflammation.Journal of Neuroinflammation.  13:3. 2016
2015 Inflammatory neuropathies: pathology, molecular markers and targets for specific therapeutic intervention.Acta Neuropathologica.  130:445-468. 2015
2015 Osteoblasts Have a Neural Origin in Heterotopic Ossification.Clinical Orthopaedics and Related Research.  473:2790-2806. 2015
2014 VIP-expressing Dendritic Cells Protect Against Spontaneous Autoimmune Peripheral Polyneuropathy.Molecular Therapy.  22:1353-1363. 2014
2014 VIP-expressing dendritic cells protect against spontaneous autoimmune peripheral polyneuropathy.Molecular Therapy.  22:1353-1363. 2014
2014 CCR2 gene deletion and pharmacologic blockade ameliorate a severe murine experimental autoimmune neuritis model of Guillain-Barré syndrome.PLoS ONE.  9:e90463. 2014
2013 A man with small vessel vasculitis presenting with brachial diplegia, multiple cranial mononeuropathies and severe orthostatic hypotension in diabetes mellitus: a case report.Journal of Medical Case Reports.  7:229. 2013
2013 A case of severe chronic progressive axonal polyradiculoneuropathy temporally associated with anti-CV2/CRMP5 antibodies.Journal of Clinical Neuromuscular Disease.  15:13-18. 2013
2013 The role of chemokines in Guillain-Barré syndrome.Muscle and Nerve.  48:320-330. 2013
2013 VEGF-A165 potently induces human blood-nerve barrier endothelial cell proliferation, angiogenesis, and wound healing in vitro.Cellular and Molecular Neurobiology.  33:789-801. 2013
2013 An immortalized human blood-nerve barrier endothelial cell line for in vitro permeability studies.Cellular and Molecular Neurobiology.  33:175-186. 2013
2013 Chemokine-dependent signaling pathways in the peripheral nervous system.Methods in Molecular Biology.  1013:17-30. 2013
2013 The molecular and biophysical characterization of the human blood-nerve barrier: current concepts.Journal of Vascular Research.  50:289-303. 2013
2012 Transient brown adipocyte-like cells derive from peripheral nerve progenitors in response to bone morphogenetic protein 2.Stem Cells Translational Medicine.  1:874-885. 2012
2012 Translational strategies in peripheral neuroinflammation and neurovascular repair.Translational Neuroscience.  3:373-383. 2012
2012 α(M)β(2)-integrin-intercellular adhesion molecule-1 interactions drive the flow-dependent trafficking of Guillain-Barré syndrome patient derived mononuclear leukocytes at the blood-nerve barrier in vitro.Journal of Cellular Physiology.  227:3857-3875. 2012
2012 Subacute brachial diplegia associated with West Nile virus myelitis.Muscle and Nerve.  45:900-904. 2012
2012 GDNF restores human blood-nerve barrier function via RET tyrosine kinase-mediated cytoskeletal reorganization.Microvascular Research.  83:298-310. 2012
2012 Behavioral, electrophysiological, and histopathological characterization of a severe murine chronic demyelinating polyneuritis model.Journal of the Peripheral Nervous System.  17:53-61. 2012
2011 Chemokine receptors as specific anti-inflammatory targets in peripheral nerves.Endocrine, Metabolic and Immune Disorders - Drug Targets.  11:141-153. 2011
2010 Selective expression and cellular localization of pro-inflammatory chemokine ligand/receptor pairs in the sciatic nerves of a severe murine experimental autoimmune neuritis model of Guillain-Barré syndrome.Neuropathology and Applied Neurobiology.  36:388-398. 2010
2010 Dorsal caudal tail and sciatic motor nerve conduction studies in adult mice: technical aspects and normative data.Muscle and Nerve.  41:850-856. 2010
2010 Clinical, electrophysiological and pathologic correlations in a severe murine experimental autoimmune neuritis model of Guillain-Barré syndrome.Journal of Neuroimmunology.  219:54-63. 2010
2010 Development and characterization of a novel human in vitro blood-nerve barrier model using primary endoneurial endothelial cells.Journal of Neuropathology and Experimental Neurology.  69:82-97. 2010
2009 Dynamic properties of eye movements in mitochondrial chronic progressive external ophthalmoplegia.Eye.  23:382-388. 2009
2008 Interferon-alpha-2b/ribavirin-induced vestibulocochlear toxicity with dysautonomia in a chronic hepatitis C patient.European Journal of Gastroenterology and Hepatology.  20:1110-1114. 2008
2008 Predictors of clinical outcome and mortality in vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography.Journal of Stroke and Cerebrovascular Diseases.  17:388-393. 2008
2008 Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migration.Clinical and Developmental Immunology.  2008:384982. 2008
2007 Chronic inflammatory demyelinating polyradiculoneuropathy presenting as cauda equina syndrome in a diabetic.Journal of the Neurological Sciences.  260:267-270. 2007
2007 Inflammatory cell migration into the central nervous system: a few new twists on an old tale.Brain Pathology.  17:243-250. 2007
2007 "Doing the locomotion" with the multistep paradigmBlood.  109:1342-1343. 2007
2006 Determinants of CCL5-driven mononuclear cell migration across the blood-brain barrier. Implications for therapeutically modulating neuroinflammation.Journal of Neuroimmunology.  179:132-144. 2006
2006 CCR5 expression on monocytes and T cells: modulation by transmigration across the blood-brain barrier in vitro.Cellular Immunology.  243:19-29. 2006
2006 Electrodiagnostic criteria for carpal tunnel syndrome in axonal polyneuropathy.Muscle and Nerve.  33:747-752. 2006
2006 Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis.Brain.  129:212-223. 2006
2006 The expression and function of chemokines involved in CNS inflammation.Trends in Pharmacological Sciences.  27:48-55. 2006
2005 Intracranial arterial dolichoectasia is associated with enlarged descending thoracic aorta.Neurology.  65:1681-1682. 2005
2005 Adult polyglucosan body disease: a case report of a manifesting heterozygote.Muscle and Nerve.  32:675-681. 2005
2005 Complete innervation of extensor digitorum brevis by accessory peroneal nerve.Neuromuscular Disorders.  15:562-564. 2005
2004 Transverse myelitis associated with Acinetobacter baumanii intrathecal pump catheter-related infection. Where was the source of the infection?Regional anesthesia.  29:503-504. 2004
2004 Clinical and radiological features of symptomatic cerebral perfusion failure due to carotid artery occlusion surgically corrected by extracranialintracranial bypass surgery.Journal of Neurology.  251:613-616. 2004
2004 Asymptomatic middle cerebral artery stenosis diagnosed by magnetic resonance angiography.Neuroradiology.  46:49-53. 2004
2004 Vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography and risk of stroke and death: a cohort study.Journal of Neurology, Neurosurgery and Psychiatry.  75:22-26. 2004
2003 Adverse reactions to mirtazapine are unlikely to be serotonin toxicity.Clinical Neuropharmacology.  26:287-288. 2003
2003 Transverse myelitis associated with Acinetobacter baumanii intrathecal pump catheter-related infection.Regional anesthesia.  28:470-474. 2003
2003 Mirtazapine-induced serotonin syndrome.Clinical Neuropharmacology.  26:54-57. 2003
2003 Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity.Epilepsy and Behavior.  4:70-75. 2003
2002 Rectus sheath hematoma complicating percutaneous endoscopic gastrostomy.Surgical Laparoscopy, Endoscopy and Percutaneous Techniques.  12:430-432. 2002
2002 Recurrent transient ischemic attacks as the initial presenting manifestation of type A aortic dissection.Annals of Vascular Surgery.  16:676-678. 2002
2002 Otalgia as the sole presenting manifestation of subdural hematoma.American Journal of Otolaryngology.  23:177-180. 2002
2002 Cervicomedullary junction compression caused by vertebral artery dolichoectasia and requiring surgical treatment. Case report.Journal of Neurosurgery.  96:140-143. 2002
2001 The preferential involvement of extraocular muscles by myasthenia gravisNeuro-Ophthalmology.  25:219-228. 2001
2001 Acute motor-sensory axonal neuropathy associated with active systemic lupus erythematosus and anticardiolipin antibodies.JCR: Journal of Clinical Rheumatology.  7:326-331. 2001
2001 Amaurosis fugax associated with phencyclidine inhalation.European Neurology.  46:98-99. 2001

Book

Year Title Altmetric
2013 Preface.  Ed. 1013.  2013
2005 Neurology oral boards review: A concise and systematic approach to clinical practice 2005

Chapter

Year Title Altmetric
2014 Atypical motor neuron disorders.  441-466. 2014
2007 G.  81-89. 2007

Principal Investigator On

  • Topiramate as a Disease Altering Therapy for Cryptogenic Sensory Peripheral Neuropalhy (CSPN)  awarded by MASSACHUSETTS GENERAL HOSPITAL 2017 - 2023
  • A Phase ll of Rituximab in Myasthenia Gravis (NN 103)  awarded by MASSACHUSETTS GENERAL HOSPITAL 2015 - 2023
  • UAB MDA CARE CENTER  awarded by Muscular Dystrophy Association 2017 - 2019
  • Private Grant  awarded by Genzyme Corporation 2017 - 2019
  • Private Grant  awarded by CSL BEHRING, LLC 2014 - 2019
  • Characterization of Agrin/LRP4 Antibody-Positive Myastenia Gravis  awarded by GEORGIA REGENTS UNIVERSITY (AUGUSTA) 2018 - 2019
  • Private Grant  awarded by CATALYST PHARMACEUTICAL PARTNERS, INC. 2016 - 2019
  • Vascular Biology of the Human Blood-Nerve Barrier  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2018
  • Characterization of Agrin/LRP4 Antibody-Positive Myasthenia Gravis  awarded by GEORGIA REGENTS UNIVERSITY (AUGUSTA) 2015 - 2017
  • Private Grant  awarded by CATALYST PHARMACEUTICAL PARTNERS, INC. 2015 - 2017
  • Private Grant  awarded by CSL BEHRING, LLC 2013 - 2017
  • MDA Sponsored Clinic Grant  awarded by Muscular Dystrophy Association 2014 - 2016
  • Alpha M Beta 2 Integrin Blockade for Acute Inflammatory Neuropathies  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2015
  • Fibronectin Peptide Antagonism for Chronic Inflammatory Neuropathies  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2014
  • Education And Training

  • Bachelor of Medicine & Surgery (MBBS), Foreign University
  • Full Name

  • Eroboghene Ubogu
  • Blazerid

  • ubogu