Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Thiol-Redox Regulation in Lung Development and Vascular Remodeling. 2019
2018 The thioredoxin reductase inhibitor auranofin induces heme oxygenase-1 in lung epithelial cells via Nrf2-dependent mechanisms 2018
2018 Selenium supplementation of lung epithelial cells enhances nuclear factor E2-related factor 2 (Nrf2) activation following thioredoxin reductase inhibition 2018
2018 Detection of dinitrosyl iron complexes by ozone-based chemiluminescence 2018
2018 Aurothioglucose does not improve alveolarization or elicit sustained Nrf2 activation in C57BL/6 models of bronchopulmonary dysplasia 2018
2018 Hemodynamic effects of glutathione-liganded binuclear dinitrosyl iron complex: Evidence for nitroxyl generation and modulation by Plasma Albumin 2018
2018 Nitrite potentiates the vasodilatory signaling of S-nitrosothiols 2018
2017 miR-29b supplementation decreases expression of matrix proteins and improves alveolarization in mice exposed to maternal inflammation and neonatal hyperoxia 2017
2016 Maternal high fat diet exposure is associated with increased hepcidin levels, decreased myelination, and neurobehavioral changes in male offspring 2016
2016 Thioredoxin reductase inhibition attenuates neonatal hyperoxic lung injury and enhances nuclear factor E2-related factor 2 activation 2016
2016 Of mice and men: Correlations between microRNA-17~92 cluster expression and promoter methylation in severe bronchopulmonary dysplasia 2016
2015 Attenuation of MIR-17∼92 cluster in bronchopulmonary dysplasia 2015
2015 DHA suppresses chronic apoptosis in the lung caused by perinatal inflammation 2015
2014 The thioredoxin system in neonatal lung disease 2014
2014 Arginase II is a target of miR-17-5p and regulates miR-17-5p expression in human pulmonary artery smooth muscle cells 2014
2014 The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndrome 2014
2014 Maternal dietary docosahexaenoic acid supplementation attenuates fetal growth restriction and enhances pulmonary function in a newborn mouse model of perinatal inflammation 2014
2013 Neonatal hyperoxic exposure persistently alters lung secretoglobins and annexin A1 2013
2013 Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation 2013
2013 Cyclooxygenase-2 in newborn hyperoxic lung injury 2013
2012 Thioredoxin reductase inhibition elicits Nrf2-mediated responses in clara cells: Implications for oxidant-induced lung injury 2012
2012 Plasma lipid metabolites are associated with gestational age but not bronchopulmonary dysplasia 2012
2012 Prenatal inflammation exacerbates hyperoxia-induced functional and structural changes in adult mice 2012
2012 Lipopolysaccharide-induced cyclooxygenase-2 expression in mouse transformed clara cells 2012
2012 Methods for the determination of plasma or tissue glutathione levels 2012
2011 Riboflavin supplementation does not attenuate hyperoxic lung injury in transgenic spc-mthGR mice 2011
2011 Maternal docosahexaenoic acid supplementation decreases lung inflammation in hyperoxia-exposed newborn mice 2011
2010 Thioredoxin-interacting protein inhibits hypoxia-inducible factor transcriptional activity 2010
2010 Hyperoxia exposure alters hepatic eicosanoid metabolism in newborn mice 2010
2009 Alterations of the thioredoxin system by hyperoxia: Implications for alveolar development 2009
2009 Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen 2009
2007 Thioredoxin-related mechanisms in hyperoxic lung injury in mice 2007

Education And Training

  • Doctor of Medicine, Indiana University System : Indiana University/Purdue University at Indianapolis 2000
  • The Ohio State University, Residency 2003
  • The Ohio State University, Postdoctoral Fellowship 2006
  • Full Name

  • Trent Tipple