Positions

Overview

  • I was originally trained as an electrical engineer, and worked in industry for a time, but then moved on to physiology. I am first and foremost a systems neuroscientist: I am interested in how information is processed and transmitted in the nervous system, not so much the details of specific genes and ion channels etc. I worked at the National Institutes of Mental Health (NIMH) before moving to the UAB School of Optometry in 1996, where I remain to this day. I have applied this interest to the visual system, exploring visual cortical neuronal dynamics and, more recently, dynamics in the retina. Finally, I have a long-standing interest in science fiction, having authored the popular "Old Guy" series of cybertank novels (available on Amazon!).
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Relationship Between Cortical Excitation and Inhibition and Task-Induced Activation and Deactivation: A Combined Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging Study at 7T in First-Episode Psychosis.Biol Psychiatry Cogn Neurosci Neuroimaging.  4:121-130. 2019
    2019 7T Proton Magnetic Resonance Spectroscopy of the Anterior Cingulate Cortex in First-Episode Schizophrenia.Schizophrenia Bulletin.  45:180-189. 2019
    2018 Juvenile Tree Shrews Do Not Maintain Emmetropia in Narrow-band Blue Light.Optometry and Vision Science.  95:911-920. 2018
    2018 The hyperopic effect of narrow-band long-wavelength light in tree shrews increases non-linearly with duration.Vision Research.  146-147:9-17. 2018
    2017 Relationship Between Alpha Rhythm and the Default Mode Network: An EEG-fMRI Study.Journal of Clinical Neurophysiology.  34:527-533. 2017
    2017 Long-wavelength (red) light produces hyperopia in juvenile and adolescent tree shrews.Vision Research.  140:55-65. 2017
    2016 The effect of saccadic eye movements on the sensor-level magnetoencephalogram.Electromyography and Clinical Neurophysiology.  128:397-407. 2016
    2016 The wavelength composition and temporal modulation of ambient lighting strongly affect refractive development in young tree shrews.Experimental Eye Research.  155:75-84. 2016
    2015 The responses of V1 cortical neurons to flashed presentations of orthogonal single lines and edges.Journal of Neurophysiology.  113:2676-2681. 2015
    2015 How does the neural retina process optical blur? Insights from emmetropization.Journal of Vision.  15:252. 2015
    2014 Vergence eye movements in patients with schizophrenia.Vision Research.  102:64-70. 2014
    2013 Roboneuron: a simple and robust real-time analog spike simulator and calibrator.Journal of Neuroscience Methods.  218:161-163. 2013
    2013 Magnetic transfer contrast accurately localizes substantia nigra confirmed by histology.Biological Psychiatry.  73:289-294. 2013
    2012 Attention influences single unit and local field potential response latencies in visual cortical area V4.Journal of Neuroscience.  32:16040-16050. 2012
    2012 Ocular convergence deficits in schizophrenia.Frontiers in Psychiatry.  3:86. 2012
    2011 Separability of stimulus parameter encoding by on-off directionally selective rabbit retinal ganglion cells.Journal of Neurophysiology.  105:2083-2099. 2011
    2011 Robust sensory gating in the cortical visual evoked potential using two spatially separated stimuli.Electromyography and Clinical Neurophysiology.  122:588-593. 2011
    2011 Short-time scale dynamics in the responses to multiple stimuli in visual cortex.Frontiers in Psychology.  2:323. 2011
    2010 The local and non-local components of the local field potential in awake primate visual cortex.Journal of Computational Neuroscience.  29:615-623. 2010
    2010 The response dynamics of rabbit retinal ganglion cells to simulated blur.Visual Neuroscience.  27:43-55. 2010
    2009 Phase-sorting of evoked potentials: pitfalls but potential.NeuroImage.  47:1830-1831. 2009
    2009 The response dynamics of primate visual cortical neurons to simulated optical blur.Visual Neuroscience.  26:411-420. 2009
    2009 The Visual Evoked Potential is independent of surface alpha rhythm phase.NeuroImage.  45:463-469. 2009
    2008 Stimulus selection via differential response latencies in visual cortical area V4.Neuroscience Letters.  435:198-203. 2008
    2007 Visual acuity of the midland banded water snake estimated from evoked telencephalic potentials.Journal of Comparative Physiology A.  193:865-870. 2007
    2005 Retinal ganglion cell coding in simulated active vision.Visual Neuroscience.  22:789-806. 2005
    2003 Video-rate and continuous visual stimuli do not produce equivalent response timings in visual cortical neurons.Visual Neuroscience.  20:495-500. 2003
    2003 The responses of visual cortical neurons encode differences across saccades.NeuroReport.  14:105-109. 2003
    2002 Responses of primate visual cortical neurons to stimuli presented by flash, saccade, blink, and external darkening.Journal of Neurophysiology.  88:2178-2186. 2002
    2002 Responses of primate visual cortical V4 neurons to simultaneously presented stimuli.Journal of Neurophysiology.  88:1128-1135. 2002
    2000 Activity of primate V1 cortical neurons during blinks.Journal of Neurophysiology.  84:2691-2694. 2000
    2000 The simultaneous coding of orientation and contrast in the responses of V1 complex cells.Experimental Brain Research.  133:293-302. 2000
    1999 The relation between V1 neuronal responses and eye movement-like stimulus presentationsNeurocomputing.  26-27:247-254. 1999
    1999 The simultaneous representation of stimulus contrast and orientation by the responses of primate V1 complex cells.Investigative Ophthalmology & Visual Science.  40:S641-S641. 1999
    1999 Temporal coding as a means of information transfer in the primate visual system.Critical Reviews in Neurobiology.  13:83-101. 1999
    1997 Insensitivity of V1 complex cell responses to small shifts in the retinal image of complex patterns.Journal of Neurophysiology.  78:3187-3197. 1997
    1997 Neuronal codes: reading them and learning how their structure influences network organization.BioSystems.  40:149-157. 1997
    1996 Latency: another potential code for feature binding in striate cortex.Journal of Neurophysiology.  76:1356-1360. 1996
    1996 Adjacent visual cortical complex cells share about 20% of their stimulus-related information.Cerebral Cortex.  6:482-489. 1996
    1995 Earth's curying capacity [3]Science.  270:898. 1995
    1995 Earth's carrying capacity.Science.  270:898. 1995
    1994 STRIATE CORTICAL-NEURONS SHOW SIMILAR RESPONSES TO ISOLUMINANT TEXTURED AS TO BLACK OR WHITE BARS, BUT WITH A 35 MS DELAYInvestigative Ophthalmology & Visual Science.  35:1976-1976. 1994
    1993 How independent are the messages carried by adjacent inferior temporal cortical neurons?Journal of Neuroscience.  13:2758-2771. 1993
    1991 Lateral geniculate neurons in behaving primates. I. Responses to two-dimensional stimuli.Journal of Neurophysiology.  66:777-793. 1991
    1991 Lateral geniculate neurons in behaving primates. II. Encoding of visual information in the temporal shape of the response.Journal of Neurophysiology.  66:794-808. 1991
    1991 Lateral geniculate neurons in behaving primates. III. Response predictions of a channel model with multiple spatial-to-temporal filters.Journal of Neurophysiology.  66:809-823. 1991
    1991 Unbiased measures of transmitted information and channel capacity from multivariate neuronal dataBiological Cybernetics.  65:305-310. 1991
    1991 Concurrent processing and complexity of temporally encoded neuronal messages in visual perception.Science.  253:675-677. 1991
    1991 Interactive effects among several stimulus parameters on the responses of striate cortical complex cells.Journal of Neurophysiology.  66:379-389. 1991
    1991 Unbiased measures of transmitted information and channel capacity from multivariate neuronal data.Biological Cybernetics.  65:305-310. 1991
    1987 Estimating left ventricular offset volume using dual-frequency conductance catheters.Journal of applied physiology: respiratory, environmental and exercise physiology.  63:872-876. 1987
    1985 Blood viscosity responses to maximal exercise in endurance-trained and sedentary female subjects.Journal of applied physiology: respiratory, environmental and exercise physiology.  59:348-353. 1985

    Chapter

    Year Title Altmetric
    2013 Cortical computations using relative spike timing.  375-389. 2013

    Research Overview

  • My current primary interest is in the neural circuitry that actively controls eye growth during infancy and childhood. We know that the retina uses visual cues to control eye growth, but we still don't know what these cues are, or how they are integrated, or what neural circuits are involved. This is of interest both scientifically and clinically, because it is the failure of this system in modern civilization that is leading to our current epidemic of myopia. I am also involved in collaborative efforts looking at cortical brain dynamics and schizophrenia.
  • Teaching Activities

  • NBL454 - Mind/Brain Course (Fall Term 2018) 2018
  • VIS755 - Electronic for Biologists (Fall Term 2018) 2018
  • VS131 - Neurobiology of Visual System (Summer Term 2018) 2018
  • VIS755 - Electronic for Biologists (Fall Term 2017) 2017
  • VS131 - Neurobiology of Visual System (Summer Term 2017) 2017
  • NBL454 - Mind/Brain Course (Spring Term 2017) 2017
  • VIS755 - Electronic for Biologists (Spring Term 2017) 2017
  • VS131 - Neurobiology of Visual System (Summer Term 2016) 2016
  • VS131 - Neurobiology of Visual System (Summer Term 2015) 2015
  • HON346 - Seminar: Hlth Related Sci (Spring Term 2015) 2015
  • VS131 - Neurobiology of Visual System (Summer Term 2014) 2014
  • VS131 - Neurobiology of Visual System (Summer Term 2013) 2013
  • VIS755 - Electronic for Biologists (Spring Term 2013) 2013
  • VIS727 - Sys Neuroscience Journal Club (Fall Term 2012) 2012
  • VIS727 - Sys Neuroscience Journal Club (Summer Term 2012) 2012
  • VS142 - Neurobiology of the Visual Sys (Spring Term 2012) 2012
  • VIS747 - Central Visual Mechanisms I (Spring Term 2012) 2012
  • PHY787 - Electronics in Physiology (Summer Term 2011) 2011
  • VS142 - Neurobiology of the Visual Sys (Spring Term 2011) 2011
  • VIS747 - Central Visual Mechanisms I (Spring Term 2011) 2011
  • VIS727 - Sys Neuroscience Journal Club (Fall Term 2010) 2010
  • VIS727 - Sys Neuroscience Journal Club (Summer Term 2010) 2010
  • VS142 - Neurobiology of the Visual Sys (Spring Term 2010) 2010
  • VIS727 - Sys Neuroscience Journal Club (Spring Term 2010) 2010
  • VIS747 - Central Visual Mechanisms I (Spring Term 2010) 2010
  • VIS727 - Sys Neuroscience Journal Club (Fall Term 2009) 2009
  • VIS727 - Sys Neuroscience Journal Club (Summer Term 2009) 2009
  • VS142 - Neurobiology of the Visual Sys (Spring Term 2009) 2009
  • VIS727 - Sys Neuroscience Journal Club (Spring Term 2009) 2009
  • VIS747 - Central Visual Mechanisms I (Spring Term 2009) 2009
  • PHY787 - Electronics in Physiology (Fall Term 2008) 2008
  • VIS727 - Sys Neuroscience Journal Club (Fall Term 2008) 2008
  • VIS727 - Sys Neuroscience Journal Club (Summer Term 2008) 2008
  • VS131 - Visual Neuroscience (Spring Term 2008) 2008
  • VIS727 - Sys Neuroscience Journal Club (Spring Term 2008) 2008
  • VIS747 - Central Visual Mechanisms I (Spring Term 2008) 2008
  • VIS727 - Sys Neuroscience Journal Club (Fall Term 2007) 2007
  • Education And Training

  • Doctor of Philosophy in Physiology, The Uniformed Services University of the Health Sciences
  • Full Name

  • Timothy Gawne
  • Blazerid

  • tgawne