Positions

Overview

  • Mechanisms of cardiovascular remodeling and repair in hypertension.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Out-of-Clinic Sympathetic Activity Is Increased in Patients With Masked Uncontrolled HypertensionHypertension.  73:132-141. 2019
    2019 Watermelon Juice: a Novel Functional Food to Increase Circulating Lycopene in Older Adult WomenPlant Foods for Human Nutrition2019
    2018 Case of refractory hypertension controlled after aortic and mitral valve replacement and coronary artery bypass graftingHypertension.  72:3-9. 2018
    2018 Refractory hypertension is not attributable to intravascular fluid retention as determined by intracardiac volumesHypertension.  72:343-349. 2018
    2017 Prevalence and clinical characteristics of refractory hypertensionJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  6. 2017
    2017 Refractory versus resistant hypertension: Novel distinctive phenotypes.Journal of nature and science.  3. 2017
    2017 Distinctive Risk Factors and Phenotype of Younger Patients with Resistant Hypertension: Age is RelevantHypertension.  69:827-835. 2017
    2017 Assessment of vascular function in low socioeconomic status preschool children: a pilot studyJournal of the American Society of Hypertension.  11:101-109. 2017
    2017 Use of Aldosterone Antagonists for Treatment of Uncontrolled Resistant HypertensionAmerican Journal of Hypertension.  30:103-109. 2017
    2017 11-beta dehydrogenase type 2 activity is not reduced in treatment resistant hypertensionAmerican Journal of Hypertension.  30:518-523. 2017
    2017 Effects of spironolactone and renal denervation treatment on blood pressure and its variability-different aspects of hypertension treatmentAmerican Journal of Hypertension.  30:12-15. 2017
    2016 Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients with Resistant HypertensionHypertension.  68:995-1003. 2016
    2016 Modulating Oxidative Stress and Inflammation in Elders: The MOXIE StudyJournal of Nutrition for the Elderly.  35:219-242. 2016
    2016 OS 24-04 A PILOT STUDY ASSESSING THE FEASIBILITY OF VASCULAR FUNCTION IN LOW SOCIOECONOMIC STATUS PRESCHOOL CHILDREN.Journal of Hypertension.  34 Suppl 1:e244. 2016
    2016 OS 33-02 IN PATIENTS WITH RESISTANT HYPERTENSION INCREASED 24-H URINARY CORTISOL LEVEL PREDICT INCREASED BODY MASS INDEX.Journal of Hypertension.  34 Suppl 1:e393. 2016
    2016 OS 33-02 IN PATIENTS WITH RESISTANT HYPERTENSION INCREASED 24-H URINARY CORTISOL LEVEL PREDICT INCREASED BODY MASS INDEX.Journal of Hypertension.  34 Suppl 1 - ISH 2016 Abstract Book:e393. 2016
    2016 The effects of urate lowering therapy on inflammation, endothelial function, and blood pressure (SURPHER) study design and rationaleControlled Clinical Trials.  50:238-244. 2016
    2016 Refractory hypertension: A novel phenotype of antihypertensive treatment failureHypertension.  67:1085-1092. 2016
    2016 Resistant and Refractory Hypertension: Antihypertensive Treatment Resistance vs Treatment FailureCanadian Journal of Cardiology.  32:603-606. 2016
    2016 Urinary sodiumexcretion predicts blood pressure response to spironolactone in patients with resistant hypertension independent of aldosterone statusJournal of Hypertension.  34:1005-1010. 2016
    2016 Effects of 6-month supplementation with β-hydroxy-β-methylbutyrate, glutamine and arginine on vascular endothelial function of older adultsEuropean Journal of Clinical Nutrition.  70:269-273. 2016
    2015 Refractory hypertension: Evidence of heightened sympathetic activity as a cause of antihypertensive treatment failureHypertension.  66:126-133. 2015
    2014 Associations between vascular health indices and serum total, free and bioavailable 25-hydroxyvitamin D in adolescentsPLoS ONE.  9. 2014
    2014 Resistant hypertension - Complex mix of secondary causes and comorbiditiesJournal of Human Hypertension.  28:1-2. 2014
    2013 Management of patients with resistant hypertension: Current treatment optionsIntegrated Blood Pressure Control.  6:139-151. 2013
    2012 Associations of C-reactive protein to indices of vascular health and the influence of serum 25(OH)D status in healthy adultsJournal of Nutrition and Metabolism.  2012. 2012
    2012 J Curve in HypertensionCurrent Cardiovascular Risk Reports.  6:281-290. 2012
    2012 Effects of antihypertensive drugs on arterial stiffnessCardiology in Review.  20:259-263. 2012
    2012 Long-term effects of aldosterone blockade in resistant hypertension associated with chronic kidney diseaseJournal of Human Hypertension.  26:502-506. 2012
    2012 Serum 25-hydroxyvitamin D and Ethnic Differences in Arterial Stiffness and Endothelial Function.Journal of Clinical Medicine Research.  4:197-205. 2012
    2012 Resistant hypertension, obstructive sleep apnoea and aldosteroneJournal of Human Hypertension.  26:281-287. 2012
    2012 Both morning and evening dosing of nebivolol reduces trough mean blood pressure surge in hypertensive patientsJournal of the American Society of Hypertension.  6:66-72. 2012
    2012 Refractory hypertension: Definition, prevalence, and patient characteristicsJournal of Clinical Hypertension.  14:7-12. 2012
    2011 The Global Burden of Cardiovascular Disease: The Role of Endothelial Function and Arterial Elasticity in Cardiovascular Disease as Novel and Emerging BiomarkersCurrent Cardiovascular Risk Reports.  5:187-195. 2011

    Chapter

    Year Title Altmetric
    2015 Stroke and hypertension in high-risk African Americans.  71-93. 2015

    Research Overview

  • We are actively studying fundamental mechanisms of pathological remodeling in hypertension and arterial stiffness, with a particular focus on inflammatory pathways and dysregulated metabolic pathways.
    We are also interested in the interplay between the mineralocorticoid receptor and adipose tissue.
    Our clinical studies examine the effects of mineralocorticoid receptor blockade on vascular function (hypertension, endothelial function, and arterial stiffness) and inflammatory and metabolic markers.
  • Teaching Overview

  • 2013-present UAB Cardiovascular (CV) Module , 1st Year Medical Students
    Module Lecturer: Dr. Dudenbostel is participating faculty - Small Group
    Preceptor and Module Lecturer - Cardiovascular Disease
  • Education And Training

  • University of Giessen Internal Medicine, Residency
  • University of Alabama at Birmingham Cardiovascular Disease, Postdoctoral Fellowship
  • Doctor of Medicine, Georg August University Gottingen 1998
  • Full Name

  • Tanja Dudenbostel