Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Differential binding of the HIV-1 envelope to phosphatidylserine receptors.BBA - Biomembranes.  1859:1962-1966. 2017
2014 L-4F inhibits lipopolysaccharide-mediated activation of primary human neutrophils.Inflammation.  37:1401-1412. 2014
2014 Emerging roles for the FCRL family members in lymphocyte biology and disease.Current Topics in Microbiology and Immunology.  382:29-50. 2014
2012 Evidence that 2-aminoethoxydiphenyl borate provokes fibrillation in perfused rat hearts via voltage-independent calcium channels.European Journal of Pharmacology.  681:60-67. 2012
2011 Pharmacological evidence for Orai channel activation as a source of cardiac abnormal automaticity.European Journal of Pharmacology.  668:208-216. 2011
2008 Quercetin induced tissue-type plasminogen activator expression is mediated through Sp1 and p38 mitogen-activated protein kinase in human endothelial cells.Journal of Thrombosis and Haemostasis.  6:976-985. 2008
2007 Mechanism by which alcohol and wine polyphenols affect coronary heart disease risk.Annals of Epidemiology.  17:S24-S31. 2007
2007 Polyphenols downregulate PAI-1 gene expression in cultured human coronary artery endothelial cells: molecular contributor to cardiovascular protection.Thrombosis Research.  121:59-65. 2007
2004 Elevated expression and release of tissue-type, but not urokinase-type, plasminogen activator after binding of autoantibodies to bullous pemphigoid antigen 180 in cultured human keratinocytes.Clinical and Experimental Immunology.  135:497-504. 2004
2002 Alcohol-induced up-regulation of fibrinolytic activity and plasminogen activators in human monocytes.Alcoholism: Clinical and Experimental Research.  26:1121-1127. 2002
2001 Ethanol-induced increased surface-localized fibrinolytic activity in cultured human endothelial cells: kinetic analysis.Alcoholism: Clinical and Experimental Research.  25:351-361. 2001
2001 Ethanol-induced up-regulation of the urokinase receptor in cultured human endothelial cells.Alcoholism: Clinical and Experimental Research.  25:163-170. 2001
2001 Polyphyenolics increase t-PA and u-PA gene transcription in cultured human endothelial cells.Alcoholism: Clinical and Experimental Research.  25:155-162. 2001
2000 Ethanol-induced up-regulation of candidate plasminogen receptor annexin II in cultured human endothelial cells.Alcoholism: Clinical and Experimental Research.  24:754-761. 2000
2000 Hypertriglyceridemic VLDL downregulates tissue plasminogen activator gene transcription through cis-repressive region(s) in the tissue plasminogen activator promoter in cultured human endothelial cells.Arteriosclerosis, Thrombosis, and Vascular Biology.  20:1675-1681. 2000
2000 Ethanol downregulates transcription of the PAI-1 gene in cultured human endothelial cells.Thrombosis Research.  97:247-255. 2000
1998 Ethanol transcriptionally upregulates t-PA and u-PA gene expression in cultured human endothelial cells.Alcoholism: Clinical and Experimental Research.  22:849-853. 1998
1998 Alcohol-induced upregulation of plasminogen activators and fibrinolytic activity in cultured human endothelial cells.Alcoholism: Clinical and Experimental Research.  22:375-381. 1998
1997 Ethanol increases surface-localized fibrinolytic activity in cultured endothelial cells.Alcoholism: Clinical and Experimental Research.  21:1471-1478. 1997
1997 Genotype-specific transcriptional regulation of PAI-1 expression by hypertriglyceridemic VLDL and Lp(a) in cultured human endothelial cells.Arteriosclerosis, Thrombosis, and Vascular Biology.  17:3215-3223. 1997
1996 Hypertriglyceridemic VLDL decreases plasminogen binding to endothelial cells and surface-localized fibrinolysis.Biochemistry.  35:6080-6088. 1996
1995 Thrombin decreases the urokinase receptor and surface-localized fibrinolysis in cultured endothelial cells.Arteriosclerosis, Thrombosis, and Vascular Biology.  15:410-419. 1995

Book

Year Title Altmetric
2014 Emerging roles for the FCRL family members in lymphocyte biology and disease.  Ed. 382.  2014

Research Overview

  • Dr. Tabengwa joined Dr. Randall Davis’ laboratory July 1, 2010 as an Assistant Professor with a strong scientific background to help establish and lead the management of a new facility on campus termed the Multidisciplinary Molecular Interaction Core (MMIC). This facility supports an NIH-funded Biacore T200 instrument that enables the characterization of protein-protein and other biomolecular interactions by surface plasmon resonance (SPR) technology. She has led in the establishment of this facility and instrumentation which has quickly grown under her management. She currently manages and operates the instrument, trains and educates new and established users, and analyzes data generated from this valuable resource for a current user base of eight different laboratories including Dr. Davis’.
  • Education And Training

  • Bachelor of Science or Mathematics in Zoology / Animal Biology, Howard University
  • Doctor of Philosophy in Molecular Biology, University of Alabama at Birmingham
  • Master of Sciences or Mathematics in Parasitology, Howard University
  • Full Name

  • Edlue Tabengwa