Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Variants in immune-related genes and genital HPV 16 persistence in menPapillomavirus Research.  7:11-14. 2019
2019 Vaginal dysbiosis and the risk of human papillomavirus and cervical cancer: systematic review and meta-analysisAmerican Journal of Obstetrics and Gynecology2019
2018 Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinomaOncotarget.  9:36836-36848. 2018
2018 Methylation of high-risk human papillomavirus genomes are associated with cervical precancer in HIV-positive womenCancer Epidemiology, Biomarkers and Prevention.  27:1407-1415. 2018
2018 Immunogenetic factors in early immune control of human immunodeficiency virus type 1 (HIV-1) infection: Evaluation of HLA class I amino acid variants in two African populationsHuman Immunology.  79:166-171. 2018
2018 Herpes Zoster in Persons Living with HIV-1 Infection: Viremia and Immunological Defects Are Strong Risk Factors in the Era of Combination Antiretroviral Therapy.Frontiers in Public Health.  6:70. 2018
2017 Genome-wide admixture and association study of subclinical atherosclerosis in the Women’s Interagency HIV Study (WIHS)PLoS ONE.  12. 2017
2017 One Size Does Not Fit All: Genetic Prediction of Kawasaki Disease Treatment Response in Diverse PopulationsCirculation: Cardiovascular Genetics.  10. 2017
2017 Local Ancestry and Clinical Cardiovascular Events Among African Americans From the Atherosclerosis Risk in Communities StudyJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  6. 2017
2017 Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events among African Americans in 2 Large Cohort StudiesCirculation: Cardiovascular Genetics.  10. 2017
2017 Cervical cancer screening intervals and management for women living with HIVAIDS.  31:1035-1044. 2017
2017 Genetic basis for variation in plasma IL-18 levels in persons with chronic hepatitis C virus and human immunodeficiency virus-1 infectionsGenes and Immunity.  18:82-87. 2017
2017 High-risk human papillomavirus infection and abnormal cervical cytology among Nepali and Bhutanese refugee women living in eastern NepalBMC Infectious Diseases.  17. 2017
2017 Spatial analysis of the regional variation of reproductive tract infections and spousal migration correlates in NepalGeospatial Health.  12. 2017
2016 Increased proportion of variance explained and prediction accuracy of survival of breast cancer patients with use of whole-genome multiomic profilesGenetics.  203:1425-1438. 2016
2016 Spousal migration and human papillomavirus infection among women in rural western NepalInternational Health.  8:261-268. 2016
2015 Challenges and Opportunities of Public Health Research in NepalKathmandu University medical journal (KUMJ).  12:1-1. 2015
2015 Preference for Human Papillomavirus–Based Cervical Cancer ScreeningJournal of Lower Genital Tract Disease.  19:119-123. 2015
2015 Deep sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individualsJournal of Human Genetics.  60:63-67. 2015
2015 Immunogenetic influences on acquisition of HIV-1 infection: Consensus findings from two African cohorts point to an enhancer element in IL19 (1q32.2)Genes and Immunity.  16:213-220. 2015
2015 Improving parental stress levels among mothers living with HIV: A randomized control group intervention studyAIDS patient care.  29:220-228. 2015
2015 Imputation of class I and II HLA loci using high-density SNPs from ImmunoChip and their associations with Kawasaki disease in family-based studyEuropean Journal of Immunogenetics.  42:140-146. 2015
2015 Mitochondrial DNA diversity in the African American populationDNA Sequence.  26:445-451. 2015
2014 High-density genotyping of immune loci in Kawasaki disease and IVIG treatment response in European-American case-parent trio studyGenes and Immunity.  15:534-542. 2014
2014 Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infectionGynecologic Oncology.  135:560-564. 2014
2014 SNP screening of central MHC-identified HLA-DMB as a candidate susceptibility gene for HIV-related Kaposi's sarcomaGenes and Immunity.  15:424-429. 2014
2014 Mitochondrial DNA variation and virologic and immunological HIV outcomes in African AmericansAIDS.  28:1871-1878. 2014
2014 Assessment of high-risk human papillomavirus infections using clinician- And self-collected cervical sampling methods in rural women from far Western NepalPLoS ONE.  9. 2014
2014 Estimating proportions of explained variance: A comparison of whole genome subsetsBMC Proceedings.  8. 2014
2014 Dense genotyping of immune-related loci identifies variants associated with clearance of HPV among HIV-positive women in the HIV epidemiology research study (HERS)PLoS ONE.  9. 2014
2014 Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infectionGynecologic Oncology2014
2014 A qualitative study on factors impacting HIV care adherence among postpartum HIV-infected women in the rural southeastern USAAIDS Care.  26:574-581. 2014
2014 HIV, inflammation, and calcium in atherosclerosisArteriosclerosis, Thrombosis, and Vascular Biology.  34:244-250. 2014
2014 A candidate gene approach for virally induced cancer with application to HIV-related Kaposi's sarcomaInternational Journal of Cancer.  134:397-404. 2014
2014 Differential gene expression landscape of co-existing cervical pre-cancer lesions using RNA-seqFrontiers in Oncology.  4. 2014
2014 Identification of sequence variants in the CCL3 chemokine gene family in the HapMap west african reference populationHuman Immunology.  75:854-858. 2014
2014 Knowledge and awareness of human papillomavirus (HPV), cervical cancer and HPV vaccine among women in two distinct nepali communitiesAsian Pacific Journal of Cancer Prevention.  15:8287-8293. 2014
2014 RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS)Atherosclerosis.  233:666-672. 2014
2013 Variants in interleukin family of cytokines genes influence clearance of high risk HPV in HIV-1 coinfected African-American adolescentsHuman Immunology.  74:1696-1700. 2013
2013 FcγR gene copy number in Kawasaki disease and intravenous immunoglobulin treatment responsePharmacogenetics -London-.  23:455-462. 2013
2013 DC-SIGN gene promoter variants and IVIG treatment response in Kawasaki diseasePediatric Rheumatology.  11. 2013
2013 RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatmentPharmacogenomics Journal.  13:330-334. 2013
2013 Short communication: Lack of occult HIV infection among non-AIDS-defining cancer patients in three academic oncology clinics in the United StatesAIDS Research and Human Retroviruses.  29:887-891. 2013
2013 Genomic Copy Number Variants: Evidence for Association with Antibody Response to Anthrax Vaccine AdsorbedPLoS ONE.  8. 2013
2013 Key considerations and current perspectives of epidemiological studies on human papillomavirus persistence, the intermediate phenotype to cervical cancerInternational Journal of Infectious Diseases.  17. 2013
2013 Prevalence and correlates of cervico-vaginal clinical syndromes among women attending a health camp in Lalitpur District of NepalKathmandu University medical journal (KUMJ).  11:268-273. 2013
2012 Prevalence of proteinuria and elevated serum cystatin c among hiv-infected adolescents in the reaching for Excellence in Adolescent Care and Health (REACH) studyJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology.  61:499-506. 2012
2012 The utility of mitochondrial and Y chromosome phylogenetic data to improve correction for population stratificationFrontiers in Genetics.  3. 2012
2012 Toll-like receptor gene variants associated with bacterial vaginosis among HIV-1 infected adolescentsJournal of Reproductive Immunology.  96:84-89. 2012
2012 Replication of RYR3 gene polymorphism association with cIMT among HIV-infected whitesAIDS.  26:1571-1573. 2012
2012 A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine AdsorbedVaccine.  30:4778-4784. 2012
2012 Erratum: Genetic variations and heterosexual HIV-1 infection: Analysis of clustered genes encoding CC-motif chemokine ligands (Genes and Immunity (2012) 13 (202-205) DOI:10.1038/gene.2011.70)Genes and Immunity.  13:444. 2012
2012 Role of activating FcγR gene polymorphisms in kawasaki disease susceptibility and intravenous immunoglobulin responseCirculation: Cardiovascular Genetics.  5:309-316. 2012
2012 Incidence, prevalence, and epidemiology of herpes simplex virus-2 in HIV-1-positive and HIV-1-negative adolescentsSexually Transmitted Diseases.  39:300-305. 2012
2012 Genetic variations and heterosexual HIV-1 infection: Analysis of clustered genes encoding CC-motif chemokine ligandsGenes and Immunity.  13:202-205. 2012
2012 Transitional probability-based model for HPV clearance in HIV-1-positive adolescent femalesPLoS ONE.  7. 2012
2011 Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected menPharmacogenetics -London-.  21:798-807. 2011
2011 Influence of host genetic and ecological factors in complex concomitant infections - relevance to sexually transmitted infectionsJournal of Reproductive Immunology.  92:27-32. 2011
2011 Natural selection among Eurasians at genomic regions associated with HIV-1 controlBMC Evolutionary Biology.  11. 2011
2011 The influence of human leukocyte antigen class I alleles and their population frequencies on human immunodeficiency virus type 1 control among African AmericansHuman Immunology.  72:312-318. 2011
2011 Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in ZambiansRetrovirology.  8. 2011
2011 Functional FCGR2B gene variants influence intravenous immunoglobulin response in patients with Kawasaki diseaseJournal of Allergy and Clinical Immunology.  128. 2011
2011 Hormonal contraceptive use and response to antiretroviral therapy among adolescent femalesHIV and AIDS Review.  10:65-69. 2011
2010 Interleukin-10 (IL-10) pathway: Genetic variants and outcomes of HIV-1 infection in African American adolescentsPLoS ONE.  5. 2010
2010 The impact of highly active antiretroviral therapy on prevalence and incidence of cervical human papillomavirus infections in HIV-positive adolescentsBMC Infectious Diseases.  10. 2010
2010 Variations in CCL3L gene cluster sequence and non-specific gene copy numbersBMC Research Notes.  3. 2010
2010 Human leukocyte antigen class I supertypes and HIV-1 control in African AmericansJournal of Virology.  84:2610-2617. 2010
2010 A genome-wide association study of carotid atherosclerosis in HIV-infected menAIDS.  24:583-592. 2010
2010 Association test of multiallelic gene copy numbers in family triosGenetic Epidemiology.  34:2-6. 2010
2009 Gene copy number: Learning to count past twoNature Medicine.  15:1127-1129. 2009
2009 The major histocompatibility complex conserved extended haplotype 8.1 in aids-related non-hodgkin lymphomaJournal of Acquired Immune Deficiency Syndromes.  52:170-179. 2009
2009 Clear and independent associations of several HLA-DRB1 alleles with diVerential antibody responses to hepatitis B vaccination in youthHuman Genetics.  126:685-696. 2009
2009 Association of Y chromosome haplogroup I with HIV progression, and HAART outcomeHuman Genetics.  125:281-294. 2009
2009 Host genetics and HIV-1 viral load set-point in African-AmericansAIDS.  23:673-677. 2009
2009 Extended IL10 haplotypes and their association with HIV progression to AIDSGenes and Immunity.  10:309-322. 2009
2008 Evaluation of IL10, IL19 and IL20 gene polymorphisms and chronic hepatitis B infection outcomeEuropean Journal of Immunogenetics.  35:255-264. 2008
2007 Interleukin-10 gene (IL10) polymorphisms and human papillomavirus clearance among immunosuppressed adolescentsCancer Epidemiology, Biomarkers and Prevention.  16:1626-1632. 2007
2006 Multiperson use of syringes among injection drug users in a needle exchange program: A gene-based molecular epidemiologic analysisJournal of Acquired Immune Deficiency Syndromes.  43:335-343. 2006
2006 Unknown biological mixtures evaluation using STR analytical quantificationELECTROPHORESIS.  27:409-415. 2006
2006 Behavioral risk exposure and host genetics of susceptibility to HIV-1 infectionJournal of Infectious Diseases.  193:16-26. 2006
2005 Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African populationJournal of Acquired Immune Deficiency Syndromes.  40:521-526. 2005
2005 Theory and methodology for utilizing genes as biomarkers to determine potential biological mixturesAnnals of Epidemiology.  15:29-38. 2005
2001 Markers for Mapping by Admixture Linkage Disequilibrium in African American and Hispanic PopulationsAmerican Journal of Human Genetics.  69:1080-1094. 2001
2000 Short tandem repeat methodology for genotypic identification of single-person versus multi-person use of syringesAIDS.  14:1507-1513. 2000
1996 3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene regionMolecular and Cellular Biology.  16:868-876. 1996
Integration of Multi-Layer Omic Data for Prediction of Disease RiskProceedings, 10th World Congress of Genetics Applied to Livestock Production.  1-6.
Multilocus Linkage Analysis of the German Asthma DataGenetic Epidemiology.  21:S210-S215.
Role and uptake of human papillomavirus vaccine in adolescent health in the United StatesAdolescent Health, Medicine and Therapeutics.  63-63.

Chapter

Year Title Altmetric
2015 Mendelian Genetics 2015
2014 Mendelian Genetics 2014
2014 Research methods for genetic studies.  233-256. 2014
2008 Methods for Genetic Studies. In Essentials of Clinical Research 2008
2008 Susceptibility to Human Infectious Diseases, Genetics of. 2008

Teaching Activities

  • EPI695 - Epidemiology Seminar (Spring Term 2019) 2019
  • EPI697 - Internship (Spring Term 2019) 2019
  • EPI798 - Doctoral Directed Research (Spring Term 2019) 2019
  • EPI799 - Dissertation Research (Spring Term 2019) 2019
  • EPI695 - Epidemiology Seminar (Fall Term 2018) 2018
  • EPI698 - Directed Research (Fall Term 2018) 2018
  • EPI703 - Grant Writing (Fall Term 2018) 2018
  • EPI795 - Epidemiology Seminar (Fall Term 2018) 2018
  • EPI798 - Doctoral Directed Research (Fall Term 2018) 2018
  • EPI799 - Dissertation Research (Fall Term 2018) 2018
  • EPI799 - Dissertation Research (Summer Term 2018) 2018
  • EPI697 - Internship (Summer Term 2018) 2018
  • EPI798 - Doctoral Directed Research (Summer Term 2018) 2018
  • EPI695 - Epidemiology Seminar (Spring Term 2018) 2018
  • EPI699 - Project Research (Spring Term 2018) 2018
  • EPI798 - Doctoral Directed Research (Spring Term 2018) 2018
  • EPI799 - Dissertation Research (Spring Term 2018) 2018
  • EPI695 - Epidemiology Seminar (Fall Term 2017) 2017
  • EPI699 - Project Research (Fall Term 2017) 2017
  • EPI731 - Genetic Epidemiology (Fall Term 2017) 2017
  • EPI731L - Genetic EPI Lab (Fall Term 2017) 2017
  • EPI795 - Epidemiology Seminar (Fall Term 2017) 2017
  • EPI798 - Doctoral Directed Research (Fall Term 2017) 2017
  • EPI799 - Dissertation Research (Fall Term 2017) 2017
  • EPI799 - Dissertation Research (Summer Term 2017) 2017
  • EPI697 - Internship (Summer Term 2017) 2017
  • EPI798 - Doctoral Directed Research (Summer Term 2017) 2017
  • EPI695 - Epidemiology Seminar (Spring Term 2017) 2017
  • EPI699 - Project Research (Spring Term 2017) 2017
  • EPI795 - Epidemiology Seminar (Spring Term 2017) 2017
  • EPI798 - Doctoral Directed Research (Spring Term 2017) 2017
  • EPI799 - Dissertation Research (Spring Term 2017) 2017
  • EPI695 - Epidemiology Seminar (Fall Term 2016) 2016
  • EPI698 - Directed Research (Fall Term 2016) 2016
  • EPI795 - Epidemiology Seminar (Fall Term 2016) 2016
  • EPI798 - Doctoral Directed Research (Fall Term 2016) 2016
  • EPI799 - Dissertation Research (Fall Term 2016) 2016
  • EPI799 - Dissertation Research (Summer Term 2016) 2016
  • EPI697 - Internship (Summer Term 2016) 2016
  • EPI799 - Dissertation Research (Summer Term 2016) 2016
  • EPI695 - Epidemiology Seminar (Spring Term 2016) 2016
  • EPI798 - Doctoral Directed Research (Spring Term 2016) 2016
  • EPI799 - Dissertation Research (Spring Term 2016) 2016
  • EPI798 - Doctoral Directed Research (Fall Term 2015) 2015
  • EPI799 - Dissertation Research (Fall Term 2015) 2015
  • EPI635 - Genetics in Public Health (Summer Term 2015) 2015
  • EPI799 - Dissertation Research (Summer Term 2015) 2015
  • EPI799 - Dissertation Research (Summer Term 2015) 2015
  • EPI798 - Doctoral Directed Research (Spring Term 2015) 2015
  • EPI799 - Dissertation Research (Spring Term 2015) 2015
  • EPI799 - Dissertation Research (Fall Term 2014) 2014
  • EPI697 - Internship (Summer Term 2014) 2014
  • EPI799 - Dissertation Research (Summer Term 2014) 2014
  • EPI731 - Genetic Epidemiology (Spring Term 2014) 2014
  • EPI731L - Genetic EPI Lab (Spring Term 2014) 2014
  • EPI798 - Doctoral Directed Research (Spring Term 2014) 2014
  • EPI799 - Dissertation Research (Spring Term 2014) 2014
  • EPI697 - Internship (Fall Term 2013) 2013
  • EPI699 - Project Research (Fall Term 2013) 2013
  • EPI798 - Doctoral Directed Research (Fall Term 2013) 2013
  • EPI799 - Dissertation Research (Fall Term 2013) 2013
  • EPI798 - Doctoral Directed Research (Summer Term 2013) 2013
  • EPI698 - Directed Research (Spring Term 2013) 2013
  • EPI798 - Doctoral Directed Research (Spring Term 2013) 2013
  • EPI799 - Dissertation Research (Spring Term 2013) 2013
  • GBS721 - Genetic Epidemiology (Spring Term 2013) 2013
  • GBS721 - GENETIC EPIDEMIOLOGY (Spring Term 2013) 2013
  • EPI697 - Internship (Fall Term 2012) 2012
  • EPI698 - Directed Research (Fall Term 2012) 2012
  • EPI798 - Doctoral Directed Research (Fall Term 2012) 2012
  • EPI799 - Dissertation Research (Fall Term 2012) 2012
  • EPI697 - Internship (Summer Term 2012) 2012
  • EPI798 - Doctoral Directed Research (Summer Term 2012) 2012
  • EPI799 - Dissertation Research (Summer Term 2012) 2012
  • EPI635 - Genetics in Public Health (Spring Term 2012) 2012
  • EPI798 - Doctoral Directed Research (Spring Term 2012) 2012
  • EPI799 - Dissertation Research (Spring Term 2012) 2012
  • GBS721 - Genetic Epidemiology (Spring Term 2012) 2012
  • EPI798 - Doctoral Directed Research (Fall Term 2011) 2011
  • EPI799 - Dissertation Research (Fall Term 2011) 2011
  • EPI697 - Internship (Summer Term 2011) 2011
  • EPI798 - Doctoral Directed Research (Summer Term 2011) 2011
  • EPI799 - Dissertation Research (Summer Term 2011) 2011
  • EPI731 - Genetic Epidemiology (Spring Term 2011) 2011
  • EPI731L - Genetic EPI Lab (Spring Term 2011) 2011
  • EPI798 - Doctoral Directed Research (Spring Term 2011) 2011
  • GBS721 - Genetic Epidemiology (Spring Term 2011) 2011
  • EPI798 - Doctoral Directed Research (Fall Term 2010) 2010
  • EPI697 - Internship (Summer Term 2010) 2010
  • EPI793 - DrPH Practicum (Summer Term 2010) 2010
  • EPI798 - Doctoral Directed Research (Summer Term 2010) 2010
  • EPI635 - Genetics in Public Health (Spring Term 2010) 2010
  • EPI699 - Project Research (Spring Term 2010) 2010
  • EPI798 - Doctoral Directed Research (Spring Term 2010) 2010
  • EPI699 - Project Research (Fall Term 2009) 2009
  • EPI798 - Doctoral Directed Research (Fall Term 2009) 2009
  • EPI697 - Internship (Summer Term 2009) 2009
  • EPI699 - Project Research (Summer Term 2009) 2009
  • EPI798 - Doctoral Directed Research (Summer Term 2009) 2009
  • EPI699 - Project Research (Spring Term 2009) 2009
  • EPI731 - Genetic Epidemiology (Spring Term 2009) 2009
  • EPI699 - Project Research (Fall Term 2008) 2008
  • EPI697 - Internship (Summer Term 2008) 2008
  • EPI699 - Project Research (Spring Term 2008) 2008
  • EPI731 - Genetic Epidemiology (Spring Term 2008) 2008
  • Education And Training

  • Doctor of Philosophy in Biological and Biomedical Sciences, Johns Hopkins University 2005
  • Master of Science in Epidemiology, Johns Hopkins University 2001
  • Full Name

  • Sadeep Shrestha