Leal, Sixto

Leal, Sixto
Assistant Professor

Assistant Professor (P), Laboratory Medicine , Clinical Pathology 2018 -

Selected Publications

Academic Article

Year	Title	Altmetric
2019	Aspergillus fumigatus corneal infection is regulated by chitin synthases and by neutrophil-derived acidic mammalian chitinase. 2019
2019	Evaluation of the ELITe InGenius PCR platform for detection of Mycoplasma pneumoniae 2019
2018	Quantitative Thresholds Enable Accurate Identification of Clostridium difficile Infection by the Luminex xTAG Gastrointestinal Pathogen Panel. 2018
2017	Current and Emerging Molecular Tests for Human Papillomavirus-Related Neoplasia in the Genomic Era. 2017
2016	Clinical Significance of Commensal Gram-Positive Rods Routinely Isolated from Patient Samples. 2016
2016	Closing the Brief Case: Recurrent Granulomatous Mastitis Due to Corynebacterium kroppenstedtii. 2016
2016	The Brief Case: Recurrent Granulomatous Mastitis Due to Corynebacterium kroppenstedtii. 2016
2016	Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus. 2016
2015	Erratum: Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2 2015
2014	Aspergillus and Fusarium corneal infections are regulated by Th17 cells and IL-17-producing neutrophils. 2014
2014	Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses. 2014
2014	Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2. 2014
2014	Fatal metacestode infection in Bornean orangutan caused by unknown Versteria species. 2014
2013	The RodA hydrophobin on Aspergillus fumigatus spores masks dectin-1- and dectin-2-dependent responses and enhances fungal survival in vivo. 2013
2013	Host response and bacterial virulence factor expression in Pseudomonas aeruginosa and Streptococcus pneumoniae corneal ulcers. 2013
2013	Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum. 2013
2012	Fungal antioxidant pathways promote survival against neutrophils during infection. 2012
2012	The role of cytokines and pathogen recognition molecules in fungal keratitis - Insights from human disease and animal models. 2012
2011	Expression of innate and adaptive immune mediators in human corneal tissue infected with Aspergillus or fusarium. 2011
2011	Co-regulation of {beta}-lactam resistance, alginate production and quorum sensing in Pseudomonas aeruginosa. 2011
2010	Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis. 2010
2008	Attenuation of Pseudomonas aeruginosa virulence by medicinal plants in a Caenorhabditis elegans model system. 2008

Book

Year	Title	Altmetric
2010	Encyclopedia of the Eye 2010

Research Overview

Development of novel molecular assays to more accurately diagnose infectious diseases. Utilizing model systems to identify key mediators of microbial detection and killing by phagocytic cells.