Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Inhibiting WNT ligand production for improved immune recognition in the Ovarian tumor microenvironmentCancers.  12. 2020
2020 Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer 2020
2019 Histone deacetylase inhibition promotes intratumoral CD8+ T-cell responses, sensitizing murine breast tumors to anti-PD1 2019
2019 Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma AngiogenesisSTEM CELLS.  37:453-462. 2019
2019 The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth 2019
2018 powerTCR: A model-based approach to comparative analysis of the clone size distribution of the T cell receptor repertoirePLoS Computational Biology.  14. 2018
2018 Reactive species balance via GTP cyclohydrolase i regulates glioblastoma growth and tumor initiating cell maintenanceNeuro-Oncology.  20:1055-1067. 2018
2018 R2DGC: Threshold-free peak alignment and identification for 2D gas chromatography-mass spectrometry in RBioinformatics.  34:1789-1791. 2018
2018 Molecular response to neoadjuvant chemotherapy in high-grade serous ovarian carcinoma 2018
2017 Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo.JCI insight.  2. 2017
2017 A genome-wide interactome of DNA-associated proteins in the human liver 2017
2017 Post-mortem molecular profiling of three psychiatric disorders 2017
2017 ARNApipe: A balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environmentsBioinformatics.  33:1727-1729. 2017
2017 Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patternsBMC Cancer.  17. 2017
2017 Differential stress induced c-Fos expression and identification of region-specific miRNA-mRNA networks in the dorsal raphe and amygdala of high-responder/low-responder ratsBehavioural Brain Research.  319:110-123. 2017
2017 Genomic regulation of invasion by STAT3 in triple negative breast cancerOncotarget.  8:8226-8238. 2017
2017 Pex35 is a regulator of peroxisome abundanceJournal of Cell Science.  130:791-804. 2017
2017 RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signatureOncotarget.  8:38668-38681. 2017
2016 RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4Molecular Oncology.  10:1169-1182. 2016
2016 Kinase gene expression profiling of metastatic clear cell renal cell carcinoma tissue identifies potential new therapeutic targetsPLoS ONE.  11. 2016
2016 Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its futureJournal of Mass Spectrometry.  51:535-548. 2016
2016 Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its futureJournal of Mass Spectrometry.  51:535-548. 2016
2016 Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation 2016
2016 Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics dataJournal of Mass Spectrometry.  461-475. 2016
2016 Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics dataJournal of Mass Spectrometry.  51:ii-iii. 2016
2016 Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974Laboratory Investigation.  96:249-259. 2016
2014 Serum metabolomic profiling in acute alcoholic hepatitis identifies multiple dysregulated pathwaysPLoS ONE.  9. 2014
2013 Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast 2013
2011 Suppression of statin effectiveness by copper and zinc in yeast and human cellsMolecular BioSystems.  7:533-544. 2011
2010 High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection 2010
2007 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectNature.  447:799-816. 2007
2007 Serum response factor binding sites differ in three human cell types 2007
2006 Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome 2006
2005 Direct isolation and identification of promoters in the human genome 2005
2004 The ENCODE (ENCyclopedia of DNA Elements) ProjectScience.  306:636-640. 2004
2004 The Role of Heat Shock Transcription Factor 1 in the Genome-wide Regulation of the Mammalian Heat Shock Response 2004
2004 An abundance of bidirectional promoters in the human genome 2004
2001 Expression of rhodopsin and arrestin during the light-dark cycle in Drosophila.Molecular Vision.  7:95-100. 2001

Education And Training

  • Doctor of Philosophy in Genetics, Stanford University 2006
  • Bachelor of Science or Mathematics in Genetics, University of Wisconsin System : Madison 2001
  • Full Name

  • Sara Cooper