Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Allosteric Role of Substrate Occupancy Toward the Alignment of P-glycoprotein Nucleotide Binding Domains.Scientific Reports.  8:14643. 2018
2018 Essential Metal Uptake in Gram-negative Bacteria: X-ray Fluorescence, Radioisotopes, and Cell Fractionation.Journal of Visualized Experiments2018
2018 Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display.PLoS ONE.  13:e0199953. 2018
2017 The crystal structure of the Yersinia pestis iron chaperone YiuA reveals a basic triad binding motif for the chelated metal.Acta Crystallographica. Section d, Structural Biology.  73:921-939. 2017
2017 Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites.Acta Crystallographica. Section d, Structural Biology.  73:557-572. 2017
2016 Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.Journal of Biological Chemistry.  291:1854-1865. 2016
2015 Tools and procedures for visualization of proteins and other biomolecules.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  110:19.12.1-19.1247. 2015
2015 ICAM-2 confers a non-metastatic phenotype in neuroblastoma cells by interaction with α-actinin.Oncogene.  34:1553-1562. 2015
2015 Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics.Scientific Reports.  5:7880. 2015
2014 In vitro evolution and affinity-maturation with Coliphage qβ display.PLoS ONE.  9:e113069. 2014
2014 Refined structures of mouse P-glycoprotein.Protein Science.  23:34-46. 2014
2009 Combining electron crystallography and X-ray crystallography to study the MlotiK1 cyclic nucleotide-regulated potassium channel.Journal of ultrastructure research.  167:220-226. 2009
2009 Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.Science.  323:1718-1722. 2009
2009 Three-dimensional structure of the human copper transporter hCTR1.Proceedings of the National Academy of Sciences.  106:4237-4242. 2009
2007 A structural perspective on copper uptake in eukaryotes.Biology of metals.  20:705-716. 2007
2006 Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture.Proceedings of the National Academy of Sciences.  103:3627-3632. 2006
2006 Mercury and zinc differentially inhibit shark and human CFTR orthologues: involvement of shark cysteine 102.American Journal of Physiology - Cell Physiology.  290:C793-C801. 2006
2006 Mercury toxicity in the shark (Squalus acanthias) rectal gland: apical CFTR chloride channels are inhibited by mercuric chloride.Journal of Experimental Zoology Part A: Comparative Experimental Biology.  305:259-267. 2006
2004 Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function.Journal of Biological Chemistry.  279:53435-53441. 2004
2002 The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria.Proceedings of the National Academy of Sciences.  99:16243-16248. 2002
1999 Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal glandAmerican Journal of Physiology - Cell Physiology.  276. 1999
1999 Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal gland.American Journal of Physiology.  276:C442-C449. 1999
1999 Molecular and functional characterization of s-KCNQ1 potassium channel from rectal gland of Squalus acanthias.Pflügers Archiv European Journal of Physiology.  437:298-304. 1999
1998 Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of CFTR trafficking in an intact epithelium.Journal of Clinical Investigation.  101:737-745. 1998
1997 Cadmium disrupts the signal transduction pathway of both inhibitory and stimulatory receptors regulating chloride secretion in the shark rectal gland.Journal of Experimental Zoology.  279:530-536. 1997

Education And Training

  • Doctor of Philosophy in Molecular Biophysics, Yale University
  • Full Name

  • Stephen Aller
  • Blazerid

  • sgaller