Selected Publications

Academic Article

Year Title Altmetric
2019 Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms 2019
2019 Evaluation of 1,2,3-Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX-770 and VX-809 2019
2018 Allosteric Role of Substrate Occupancy Toward the Alignment of P-glycoprotein Nucleotide Binding Domains 2018
2018 Essential metal uptake in gram-negative bacteria: X-ray fluorescence, radioisotopes, and cell fractionation 2018
2018 Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display. 2018
2017 The crystal structure of the Yersinia pestis iron chaperone YiuA reveals a basic triad binding motif for the chelated metal 2017
2017 Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites 2017
2016 Channel gating regulation by the cystic fibrosis transmembrane conductance regulator (CFTR) first cytosolic loop 2016
2015 ICAM-2 confers a non-metastatic phenotype in neuroblastoma cells by interaction with α-actinin 2015
2015 Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics 2015
2015 Tools and procedures for visualization of proteins and other biomolecules 2015
2014 In vitro evolution and affinity-maturation with Coliphage Qβ display 2014
2014 Refined structures of mouse P-glycoprotein 2014
2009 Combining electron crystallography and X-ray crystallography to study the MlotiK1 cyclic nucleotide-regulated potassium channel 2009
2009 Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding 2009
2009 Three-dimensional structure of the human copper transporter hCTR1 2009
2007 A structural perspective on copper uptake in eukaryotes 2007
2006 Mercury toxicity in the shark (Squalus acanthias) rectal gland: Apical CFTR chloride channels are inhibited by mercuric chloride 2006
2006 Projection structure of the human copper transporter CTR1 at 6-Å resolution reveals a compact trimer with a novel channel-like architecture 2006
2006 Mercury and zinc differentially inhibit shark and human CFTR orthologues: Involvement of shark cysteine 102 2006
2004 Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function 2004
2002 The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria 2002
1999 Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal gland 1999
1999 Molecular and functional characterization of s-KCNQ1 potassium channel from rectal gland of Squalus acanthias 1999
1999 Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal gland. 1999
1998 Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias: Acute regulation of CFTR trafficking in an intact epithelium 1998
1997 Cadmium disrupts the signal transduction pathway of both inhibitory and stimulatory receptors regulating chloride secretion in the shark rectal gland 1997

Education And Training

  • The Scripps Research Institute, Postdoctoral Fellowship 2009
  • Full Name

  • Stephen Aller