Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Reduction in urinary oxalate excretion in mouse models of Primary Hyperoxaluria by RNA interference inhibition of liver lactate dehydrogenase activity.  BBA - Molecular Basis of Disease.  1865:2203-2209. 2019
2018 Hydroxyproline metabolism and oxalate synthesis in primary hyperoxaluria.  Journal of the American Society of Nephrology.  29:1615-1623. 2018
2016 High throughput cell-based assay for identification of glycolate oxidase inhibitors as a potential treatment for Primary Hyperoxaluria Type 1.  Scientific Reports.  6. 2016
2016 Effects of alanine: Glyoxylate aminotransferase variants and pyridoxine sensitivity on oxalate metabolism in a cell-based cytotoxicity assay.  BBA - Molecular Basis of Disease.  1862:1055-1062. 2016
2016 MP67-02 THE EFFECT OF ALANINE ON CELL VIABILITY AND AGT ACTIVITY IN TRANSFORMED CHINESE HAMSTER OVARY CELLS.  Journal of Urology, The.  195:e881-e881. 2016
2016 MP67-03 MITOCHONDRIAL IMPLICATIONS OF GLYCOLATE METABOLISM IN PRIMARY HYPEROXALURIA.  Journal of Urology, The.  195:e881-e882. 2016
2016 Metabolism of 13C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.  BBA - Molecular Basis of Disease.  1862:233-239. 2016
2015 MP34-04 INHIBITION OF GLYCOLATE OXIDASE REDUCES URINARY OXALATE EXCRETION IN A MOUSE MODEL OF PRIMARY HYPEROXALURIA TYPE 1.  Journal of Urology, The.  193:e411-e411. 2015
2015 Development of a phenotypic high-content assay to identify pharmacoperone drugs for the treatment of primary hyperoxaluria type 1 by high-throughput screening.  ASSAY and Drug Development Technologies.  13:16-24. 2015
2015 A mutation creating an out-of-frame alternative translation initiation site in the GRHPR 5′UTR causing primary hyperoxaluria type II.  Clinical Genetics.  88:494-498. 2015
2015 Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine: Glyoxylate aminotransferase causing primary hyperoxaluria type I.  Human Molecular Genetics.  24:5500-5511. 2015
2014 Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1.  Proceedings of the National Academy of Sciences.  111:14406-14411. 2014
2014 Factors influencing clinical outcome in patients with primary hyperoxaluria type 1.  Kidney International.  86:1074-1076. 2014
2013 Multiple mechanisms of action of pyridoxine in primary hyperoxaluria type 1.  BBA - Molecular Basis of Disease.  1832:1776-1783. 2013
2013 Four of the most common mutations in primary hyperoxaluria type 1 unmask the cryptic mitochondrial targeting sequence of alanine:glyoxylate aminotransferase encoded by the polymorphic minor allele.  Journal of Biological Chemistry.  288:2475-2484. 2013
2012 The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase.  The International journal of biochemistry.  44:536-546. 2012
2012 Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment..  Nephrology Dialysis Transplantation.  27:1729-1736. 2012
2011 Hyperoxalurie primitive de type 1 : expérience française.  Néphrologie and Thérapeutique.  7:289-289. 2011
2011 Primary hyperoxaluria.  Néphrologie and Thérapeutique.  7:249-259. 2011
2011 Primary hyperoxaluria..  International Journal of Nephrology.  2011:864580. 2011
2011 Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation.  Journal of the American Society of Nephrology.  22:579-585. 2011
2010 Tacrolimus nephrotoxicity: Beware of the association of diarrhea, drug interaction and pharmacogenetics.  Pediatric Nephrology.  25:965-969. 2010
2010 Genotype-phenotype correlation in primary hyperoxaluria type 1: The p.Gly170Arg AGXT mutation is associated with a better outcome.  Kidney International.  77:443-449. 2010
2010 Bone metabolism in oxalosis: A single-center study using new imaging techniques and biomarkers.  Pediatric Nephrology.  25:1081-1089. 2010
2010 Primary hyperoxaluria type 1: Strategy for organ transplantation.  Current Opinion in Organ Transplantation.  15:590-593. 2010
2009 Survey of First-Year Medical Students to Assess Their Knowledge and Attitudes Toward Organ Transplantation and Donation.  Transplantation Proceedings.  41:634-638. 2009
2009 Disease recurrence in paediatric renal transplantation.  Pediatric Nephrology.  24:2097-2108. 2009
2009 Effect of conservative treatment on the renal outcome of children with primary hyperoxaluria type 1.  Kidney International.  76:767-773. 2009
2008 Hyperuricemia after liver transplantation in children.  Pediatric Transplantation.  12:847-853. 2008
2007 New treatment strategies for proliferative lupus nephritis: Keep children in mind!.  Lupus.  16:684-691. 2007
2006 Primary hyperoxaluria type 1: Still challenging!.  Pediatric Nephrology.  21:1075-1081. 2006
2006 Hyperoxalurie primitive.  EMC - Néphrologie.  1:1-10. 2006

Education And Training

Full Name

  • Sonia Fargue

    • Blazerid

  • sfargue