Positions

Overview

  • Seth Landefeld is Chair, Department of Medicine and the Spencer Chair in Medical Science Leadership.

    Dr. Landefeld brings to UAB an infectious enthusiasm for all the wonderful opportunities in academic medicine – to care for people, to teach, to discover, and to build a healthy society. Recognizing the UAB Department of Medicine as a well established national leader, he envisions the Department as the go-to department in the United States for faculty, learners, and staff who have the ambition, ability, and drive to work together with their colleagues at UAB to make it the most exciting academic medical center in the country.

    Prior to joining UAB in September 2012, Dr. Landefeld founded and led the development of UCSF’s Division of Geriatrics, and he ultimately served as Associate Chair of the Department of Medicine for Strategic Planning and Implementation. With over 30 faculty, the Division has established a record of innovation in research, education, and patient care and has emerged as a national leader in the development of outstanding faculty. The Division’s outstanding faculty and innovative programs have attracted increasing support from the philanthropic community, with annual gifts of $1 million and an endowment of over $5 million. At UCSF, Landefeld also directed the Hartford Foundation Center of Excellence in Academic Geriatrics, founded Program for the Aging Century, and led the editorial team that produces JAMA’s series, “Care of the Aging Patient.”

    Dr. Landefeld’s work has aimed to transform and personalize health care to meet the needs of older Americans and their families in this Aging Century, a century that will be dominated by the medical and social issues of the aging global population. His research has improved outcomes of older persons with serious illness. In landmark studies of acutely ill hospitalized elders, Landefeld and his colleagues invented the Acute Care for Elders (ACE) Unit, a novel method for improving patients’ functional outcomes. This model has been adapted at medical centers nationwide. In incremental studies of anticoagulant therapy, he developed the first valid, reliable measure of hemorrhagic complications, designed and validated risk assessment indices for anticoagulant-related bleeding, developed interventions to prevent major bleeding, and demonstrated their efficacy in clinical trials.

    Dr. Landefeld completed his undergraduate work at Harvard and New College, Oxford, where he was a Rhodes Scholar. He received his M.D. from Yale. He trained in internal medicine at UCSF and in clinical epidemiology at Harvard Medical School. He is a member of the American Society for Clinical Investigation and the Association of American Physicians and was recently a Fellow at the Center for Advanced Study in the Behavioral Sciences at Stanford University. He is Past-President of the Society of General Internal Medicine and served on the Boards of the American Geriatrics Society, the Association of Directors of Geriatric Academic Programs, and San Francisco’s Institute on Aging. In 2011, Dr. Landefeld received the Robert J. Glaser Award “For Exceptional Contributions to Education and Research,” the highest award of the Society of General Internal Medicine.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Screening for Asymptomatic Bacteriuria in Adults: US Preventive Services Task Force Recommendation Statement 2019
    2019 Medication use to reduce risk of breast cancer: Us preventive services task force recommendation statement 2019
    2019 Screening for Hepatitis B Virus Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement 2019
    2019 Screening for HIV Infection: US Preventive Services Task Force Recommendation Statement 2019
    2019 Preexposure prophylaxis for the prevention of HIV infection: US preventive services task force recommendation statement 2019
    2019 In Reply 2019
    2019 Screening for Elevated Blood Lead Levels in Children and Pregnant Women: US Preventive Services Task Force Recommendation Statement 2019
    2019 Exercise Programs in Older Adults - A Prescription for Fall Reduction 2019
    2019 Interventions to Prevent Perinatal Depression: US Preventive Services Task Force Recommendation Statement 2019
    2019 Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement 2019
    2018 Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement 2018
    2018 Interventions to Prevent Child Maltreatment: US Preventive Services Task Force Recommendation Statement 2018
    2018 Overcoming Inertia to Improve Medication Use and Deprescribing 2018
    2018 Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement 2018
    2018 Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: US Preventive Services Task Force Final Recommendation Statement 2018
    2018 Behavioral weight loss interventions to prevent obesity-relatedmorbidity and mortality in adults US preventive services task force recommendation statement 2018
    2018 Screening for syphilis infection in pregnant women us preventive services task force reaffirmation recommendation statement 2018
    2018 Natural history of lesions suspicious for basal cell carcinoma in older adults in Ikaria, Greece 2018
    2018 Screening for cervical cancer us preventive services task force recommendation statement 2018
    2018 Screening for atrial fibrillation with electrocardiography: US preventive services task force recommendation statement 2018
    2018 Risk assessment for cardiovascular disease with nontraditional risk factors: US preventive services task force recommendation statement 2018
    2018 Screening for peripheral artery disease and cardiovascular disease risk assessment with the Ankle-Brachial Index: US Preventive Services Task Force Recommendation Statement 2018
    2018 Screening for osteoporosis to prevent fractures us preventive services task force recommendation statement 2018
    2018 Screening for cardiovascular disease risk with electrocardiography us preventive services task force recommendation statement 2018
    2018 Screening for prostate cancer USPreventive servicestaskforcerecommendation statement 2018
    2018 Screening for ovarian cancer US preventive services task force recommendation statement 2018
    2018 Screening for adolescent Idiopathic Scoliosis US preventive services task force recommendation statement 2018
    2017 Hormone Therapy for the primary prevention of chronic conditions in postmenopausal women US preventive services task force recommendation statement 2017
    2017 The costs and benefits of hospital care by primary physicians: Continuity counts 2017
    2017 Vision screening in children aged 6 months to 5 years: US preventive services task force recommendation statement 2017
    2017 Screening for Preeclampsia: US Preventive Services Task Force Recommendation Statement 2017
    2017 A triumph for the agency for healthcare research and quality safety program for long-term care moving beyond "round up the usual suspects 2017
    2017 Behavioral counseling to promote a healthful diet and physical activity for cardiovascular disease prevention in adultswithout cardiovascular risk factors: US preventive services task force recommendation statement 2017
    2017 Screening for obesity in children and adolescents us preventive services task force recommendation statement 2017
    2017 Screening for thyroid cancer: US preventive services task force recommendation statement 2017
    2017 Screening for Preeclampsia US preventive services task force recommendation statement 2017
    2017 Developing recommendations for evidence-based clinical preventive services for diverse populations: Methods of the u.s. Preventive services task force 2017
    2017 Screening for celiac disease: US preventive services task force recommendation statement 2017
    2017 Screening for gynecologic conditions with pelvic examination US preventive services task force recommendation statement 2017
    2017 Screening for obstructive sleep apnea in adults us preventive services task force recommendation statement 2017
    2017 Folic acid supplementation for the prevention of neural tube defects US preventive services task force recommendation statement 2017
    2016 Serologic screening for genital herpes infection: US preventive services task force recommendation statement 2016
    2016 Statin use for the primary prevention of cardiovascular disease in adults: US preventive services task force recommendation statement 2016
    2016 Primary Care Interventions to Support Breastfeeding: US Preventive Services Task Force Recommendation Statement. 2016
    2016 Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. 2016
    2016 Screening for skin cancer US preventive services task force recommendation statement 2016
    2016 Aspirin use for the primary prevention of cardiovascular disease and colorectal cancer: U.S. preventive services task force recommendation statement 2016
    2016 Screening for colorectal cancer: US preventive services task force recommendation statement 2016
    2016 Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: US Preventive Services Task Force Recommendation Statement 2016
    2016 Screening for chronic obstructive pulmonary disease US preventive services task force recommendation statement 2016
    2016 Change, Challenge and Opportunity: Departments of Medicine and Their Leaders. 2016
    2016 Screening for latent tuberculosis infection in adults: US preventive services task force recommendation statement 2016
    2016 THE STRUCTURE AND FUNCTION OF DEPARTMENTS OF MEDICINE 2016
    2014 A "green banana" worth buying in older age: Colorectal cancer screening for persons older than 75 years without previous screening 2014
    2013 Treatment of nonfatal conditions at the end of life: Nonmelanoma skin cancer 2013
    2013 Recovery, dependence or death after discharge 2013
    2013 Prediction of recovery, dependence or death in elders who become disabled during hospitalization 2013
    2013 In reply 2013
    2013 Treatment of nonmelanoma skin cancer--reply. 2013
    2012 Depressive symptoms after hospitalization in older adults: Function and mortality outcomes 2012
    2012 Nurse-led intervention to improve surrogate decision making for patients with advanced critical illness. 2012
    2012 Longitudinal assessment of symptom severity among hospitalized elders diagnosed with cancer, heart failure, and chronic obstructive pulmonary disease 2012
    2012 Acute care for elders units produced shorter hospital stays at lower cost while maintaining patients' functional status 2012
    2012 An assessment of the screening performance of a single-item measure of depression from the edmonton symptom assessment scale among chronically ill hospitalized patients 2012
    2012 Functional status after colon cancer surgery in elderly nursing home residents 2012
    2012 Depression is a common and chronic comorbidity in patients with interstitial lung disease 2012
    2012 Industry Support of CME - Are we at the tipping point? 2012
    2011 Major abdominal surgery in nursing home residents: A national study 2011
    2011 Learning the respective roles of warfarin and dabigatran to prevent stroke in patients with nonvalvular atrial fibrillation. 2011
    2011 Goals of care for hip fracture promoting independence and reducing mortality 2011
    2011 Academic geriatrics in Singapore 2011
    2011 A clinical index to stratify hospitalized older adults according to risk for new-onset disability 2011
    2011 Depression and functional status are strongly associated with dyspnea in interstitial lung disease 2011
    2010 Hospital-based palliative medicine consultation: a randomized controlled trial. 2010
    2010 Improving primary care for older patients: Challenge for the aging century 2010
    2009 Clinical care in the aging century - Announcing "care of the aging patient: From evidence to action" 2009
    2009 Functional status of elderly adults before and after initiation of dialysis 2009
    2009 Agreement between drugs-to-avoid criteria and expert assessments of problematic prescribing 2009
    2009 Unraveling the relationship between literacy, language proficiency, and patient-physician communication 2009
    2009 Current guidelines for using angiotensin-converting enzyme inhibitors and angiotensin II-receptor antagonists in chronic kidney disease: Is the evidence base relevant to older adults? 2009
    2009 Association between hospital-reported leapfrog safe practices scores and inpatient mortality 2009
    2009 Pragmatic approaches that improve care for geriatric conditions: Balancing the promise and the peril of quality indicators: Editorial 2009
    2009 The neurontin legacy - Marketing through misinformation and manipulation 2009
    2009 A clinical framework for improving the advance care planning process: Start with patients' self-identified barriers 2009
    2008 Recovery of activities of daily living in older adults after hospitalization for acute medical illness 2008
    2008 Reach and impact of a mass media event among vulnerable patients: The Terri Schiavo story 2008
    2008 Noninvasive diagnosis of deep vein thrombosis. 2008
    2008 CHAMP trains champions: hospitalist-educators develop new ways to teach care for older patients. 2008
    2008 Should we use large scale healthcare interventions without clear evidence that benefits outweigh costs and harms? No. 2008
    2008 Engagement in multiple steps of the advance care planning process: A descriptive study of diverse older adults 2008
    2008 Health care for older Americans with multiple chronic conditions: A research agenda 2008
    2007 An advance directive redesigned to meet the literacy level of most adults: A randomized trial 2007
    2007 Age affects outcomes in chronic kidney disease 2007
    2007 The relationship between self-rated health and mortality in older black and white Americans 2007
    2007 The tension between needing to improve care and knowing how to do it 2007
    2007 An electronic medical record intervention increased nursing home advance directive orders and documentation. 2007
    2007 Quality-of-life outcomes of treatments for cutaneous basal cell carcinoma and squamous cell carcinoma 2007
    2007 Response letter to Dr. Cheng [5] 2007
    2007 What's in a name? Use of brand versus generic drug names in United States outpatient practice 2007
    2007 Characteristics and impact of drug detailing for gabapentin 2007
    2007 In response 2007
    2007 Conflicts and concordance between measures of medication prescribing quality 2007
    2006 Polypharmacy and prescribing quality in older people. 2006
    2006 Erratum: Use of a modified informed consent process among vulnerable patients: A descriptive study (Journal of General Internal Medicine (2006) 21, (867-873)) 2006
    2006 Narrative review: The promotion of gabapentin: An analysis of internal industry documents 2006
    2006 Use of a modified informed consent process among vulnerable patients: A descriptive study 2006
    2006 Mortality risk stratification in chronic kidney disease: One size for all ages? 2006
    2006 Care of hospitalized older patients: opportunities for hospital-based physicians. 2006
    2006 The prophylaxis of medical patients for thromboembolism pilot study 2006
    2005 Disparities between black and white patients in functional improvement after hospitalization for an acute illness 2005
    2005 Reports of financial disability predict functional decline and death in older patients discharged from the hospital 2005
    2004 Commercial support and bias in pharmaceutical research 2004
    2004 The relation of autopsy rate to physicians' beliefs and recommendations regarding autopsy 2004
    2003 Discussion of Medical Errors in Morbidity and Mortality Conferences 2003
    2003 Diagnosis-Related Group-Adjusted Hospital Costs Are Higher in Older Medical Patients with Lower Functional Status 2003
    2003 General Internal Medicine and Geriatrics: Building a Foundation to Improve the Training of General Internists in the Care of Older Adults 2003
    2003 Training in the care of older adults: Opportunity knocks for general internal medicine 2003
    2003 Variation in Use of Broad-Spectrum Antibiotics for Acute Respiratory Tract Infection [4] (multiple letters) 2003
    2003 Unsteadiness reported by older hospitalized patients predicts functional decline 2003
    2003 Changing Use of Antibiotics in Community-Based Outpatient Practice, 1991-1999 2003
    2003 Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: Increased vulnerability with age 2003
    2003 Predictors of Broad-Spectrum Antibiotic Prescribing for Acute Respiratory Tract Infections in Adult Primary Care 2003
    2003 Cognitive screening predicts magnitude of functional recovery from admission to 3 months after discharge in hospitalized elders 2003
    2002 A curriculum for training quality scholars to improve the health and health care of veterans and the community at large. 2002
    2002 Finding the target: getting started with quality of care and health services research. 2002
    2001 Multicomponent comprehensive care was as effective as usual care for decreasing major bleeding in older patients on warfarin 2001
    2001 Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization 2001
    2001 Improving care for hospitalized elders 2001
    2001 Outcomes-based trial of an inpatient nurse practitioner service for general medical patients 2001
    2001 Introduction to the supplement 2001
    2000 A multicomponent intervention to prevent major bleeding complications in older patients receiving warfarin: A randomized, controlled trial 2000
    2000 Delivery of preventive services to older black patients using neighborhood health centers 2000
    2000 Different strokes for different folks: are differences in physician practices good for older persons with diabetes? 2000
    1999 Depressive symptoms and 3-year mortality in older hospitalized medical patients 1999
    1999 Health status versus quality of life in older patients: Does the distinction matter? 1999
    1999 When doctors marry doctors: A survey exploring the professional and family lives of young physicians 1999
    1999 Effects of functional status changes before and during hospitalization on nursing home admission of older adults 1999
    1999 The relationship between clinical assessments of nutritional status and adverse outcomes in older hospitalized medical patients 1999
    1999 When doctors marry doctors [3] (multiple letters) 1999
    1998 Clinical intervention trials: The ACE unit 1998
    1998 Strain in African American and White American caregivers of hospitalized elderly: Implications for discharge planning 1998
    1998 Prospective evaluation of an index for predicting the risk of major bleeding in outpatients treated with warfarin 1998
    1998 The relation between health status changes and patient satisfaction in older hospitalized medical patients 1998
    1998 Factors associated with the use of flexible sigmoidoscopy as a screening test for the detection of colorectal carcinoma by primary care physicians 1998
    1998 A patient-centered model of acute care for elders. 1998
    1998 Examining older people for carotid bruits: listen to your patient, not her neck. 1998
    1998 Improving functional outcomes in older patients: lessons from an acute care for elders unit. 1998
    1998 Preventing disability in older people with chronic disease: What is a doctor to do? 1998
    1998 What patients should ask of consumers' guides to health care quality 1998
    1997 Atrial fibrillation and stroke: What we know, what's new, and what we should do now 1997
    1997 Primary care physician recommendations for colorectal cancer screening: Patient and practitioner factors 1997
    1997 Measuring prognosis and case mix in hospitalized elders: The importance of functional status 1997
    1997 A prognostic model for patients with end-stage liver disease 1997
    1997 Depression, smoking, and health status [5] (multiple letters) 1997
    1997 Do acute care for elders units increase hospital costs? A cost analysis using the hospital perspective 1997
    1997 Health services research and the endocrinologist 1997
    1997 Relation between symptoms of depression and health status outcomes in acutely ill hospitalized older persons 1997
    1996 Drug companies and information about drugs: recommendations for doctors - Characteristics of materials distributed by drug companies: Four points of view 1996
    1996 Is economic hardship on the families of the seriously ill associated with patient and surrogate care preferences? 1996
    1996 Using the biopsychosocial model in practice - Improving the care of patients with late-life depression 1996
    1996 Functional outcomes of acute medical illness and hospitalization in older persons 1996
    1996 Hospital admission risk profile (HARP): identifying older patients at risk for functional decline following acute medical illness and hospitalization. 1996
    1996 Failure to prescribe warfarin to patients with nonrheumatic atrial fibrillation 1996
    1996 Randomized controlled trial of an inpatient nurse practitioner service 1996
    1996 Surgery for colorectal cancer: Race-related differences in rates and survival among medicare beneficiaries 1996
    1996 The annual guide to 'America's Best Hospitals': Evidence of influence among health care leaders 1996
    1996 Why isn't warfarin prescribed to patients with nonrheumatic atrial fibrillation? 1996
    1995 Acceptance of external funds by physician organizations - Issues and policy options 1995
    1995 Outcomes of warfarin therapy: lessons from the real world. 1995
    1995 The cost of topical drugs for dermatophyte infections. 1995
    1995 Long-term Outcomes of Deep-Vein Thrombosis 1995
    1995 A randomized trial of care in a hospital medical unit especially designed to improve the functional outcomes of acutely ill older patients 1995
    1995 A national population‐based study of incidence of colorectal cancer and age. Implications for screening in older Americans 1995
    1995 Anticoagulants in Older Patients: A Safety Perspective 1995
    1995 Cultures of Skin Biopsy Tissue From Immunocompromised Patients With Cancer and Rashes 1995
    1995 Erratum to Anticoagulants in older patients: a safety perspective 1995
    1995 Improving primary care in academic medical centers the role of firm systems 1995
    1995 Nurse practitioners in a teaching hospital 1995
    1995 Outcomes of Warfarin Therapy: Lessons From the Real World 1995
    1995 Predicting future functional status for seriously ill hospitalized adults. The SUPPORT prognostic model 1995
    1995 Predictive validity of the nursing severity index in patients with musculoskeletal disease 1995
    1994 A Cost Analysis of Topical Drug Regimens for Dermatophyte Infections 1994
    1994 An index of symptoms for infection with human immunodeficiency virus: reliability and validity. 1994
    1994 Physicians’ Behavior and Their Interactions With Drug Companies: A Controlled Study of Physicians Who Requested Additions to a Hospital Drug Formulary 1994
    1994 Physicians’ Behavior and Their Interactions With Drug Companies: A Controlled Study of Physicians Who Requested Additions to a Hospital Drug Formulary 1994
    1994 Evaluation of a Treatment Limitation Policy With a Specific Treatment-Limiting Order Page 1994
    1994 A Medical Unit for the Acute Care of the Elderly 1994
    1994 Developing guidelines for local use: algorithms for cost-efficient outpatient management of cardiovascular disorders in a VA Medical Center. 1994
    1994 Physicians’ behavior and their interactions with drug companies: A controlled study of physicians who requested additions to a hospital drug formulary 1994
    1994 Risk for anticoagulant-related bleeding: A meta-analysis 1994
    1993 The Spring Meetings – Are They Dying? 1993
    1993 Do Older Medicare Patients Cost Hospitals More?: Evidence From an Academic Medical Center 1993
    1993 Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention 1993
    1993 Rashes in Immunocompromised Cancer Patients: The Diagnostic Yield of Skin Biopsy and Its Effects on Therapy 1993
    1993 Urosepsis in the elderly: Clinical and microbiologic characteristics 1993
    1992 Preventing anticoagulant-related bleeding [6] 1992
    1992 Sexual behavior, knowledge, and attitudes about AIDS among college freshmen 1992
    1992 Diagnostic judgments of nurse practitioners providing primary gynecologic care - A quantitative analysis 1992
    1992 Consultation and guidelines to reduce anticoagulant-related bleeding 1992
    1992 Development and validation of the nursing severity index: A new method for measuring severity of illness using nursing diagnoses 1992
    1992 Guideline-based consultation to prevent anticoagulant-related bleeding. A randomized, controlled trial in a teaching hospital 1992
    1992 The cleveland veterans affairs medical center firm system 1992
    1991 Clinical correlates predictive of deep vein thrombosis 1991
    1991 Doctors, drug companies and gifts. 1991
    1991 Risk for bleeding in patients starting anticoagulants 1991
    1990 A new diagnostic index for predicting cervical infection with either Chlamydia trachomatis or Neisseria gonorrhoeae 1990
    1990 In Reply 1990
    1990 A bleeding risk index for estimating the probability of major bleeding in hospitalized patients starting anticoagulant therapy 1990
    1990 Clinical findings associated with acute proximal deep vein thrombosis: A basis for quantifying clinical judgment 1990
    1990 Failure to limit quantities of benzodiazepine hypnotic drugs for outpatients: Placing the elderly at risk 1990
    1990 Outcomes in support 1990
    1990 Patient characteristics in support: Functional status 1990
    1990 The relation of chlamydial infection of the cervix to time elapsed from the onset of menses. 1990
    1989 Doctors, Drug Companies, and Gifts 1989
    1989 In Reply 1989
    1989 ‘Brain Death’ and Organ Retrieval: A Cross-sectional Survey of Knowledge and Concepts Among Health Professionals 1989
    1989 Bleeding in outpatients treated with warfarin: relation to the prothrombin time and important remediable lesions 1989
    1989 Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy 1989
    1989 The Autopsy in Clinical Medicine 1989
    1989 The autopsy in quality assurance: History, current status, and future directions 1989
    1989 The bleeding severity index: Validation and comparison to other methods for classifying bleeding complications of medical therapy 1989
    1989 The value of autopsy in modern oncology 1989
    1988 Diagnostic Yield of the Autopsy 1988
    1988 Prognostic factors in acquired immunodeficiency syndrome 1988
    1988 Diagnostic Yield of the Autopsy in a University Hospital and a Community Hospital 1988
    1988 Students' sexual behavior, knowledge, and attitudes relating to the acquired immunodeficiency syndrome 1988
    1987 Assessing the preventability of emergency hospital admissions. A method for evaluating the quality of medical care in a primary care facility. 1987
    1987 Identification and preliminary validation of predictors of major bleeding in hospitalized patients starting anticoagulant therapy 1987
    1983 Clomiphene-responsive hypogonadism in sickle cell anemia 1983

    Book

    Year Title Altmetric
    2014 Foreword: The story of ACE 2014

    Chapter

    Year Title Altmetric
    2014 Physician assistants in urban neighborhood health centers.  107-126. 2014

    Full Name

  • Seth Landefeld