Selected Publications

Academic Article

Year Title Altmetric
2020 Mitochondrial genetics cooperate with nuclear genetics to selectively alter immune cell development/trafficking 2020
2020 Role of the tumor microenvironment in regulating the anti-metastatic effect of KISS1 2020
2019 Early Life Supraphysiological Levels of Oxygen Exposure Permanently Impairs Hippocampal Mitochondrial Function 2019
2019 The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 and Promotes Tumorigenesis in Mice 2019
2019 Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop 2019
2019 KISS1 in breast cancer progression and autophagy 2019
2019 Mitochondrial genetics regulate nuclear gene expression through metabolites 2019
2019 Defining the Hallmarks of Metastasis 2019
2019 HDAC inhibition induces autophagy and mitochondrial biogenesis to maintain mitochondrial homeostasis during cardiac ischemia/reperfusion injury 2019
2019 The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered 2019
2019 Bioenergetics and translational metabolism: Implications for genetics, physiology and precision medicine 2019
2019 Mitochondrial DNA variation modulates alveolar development in newborn mice exposed to hyperoxia 2019
2018 Mitochondrial polymorphisms contribute to aging phenotypes in MNX mouse models 2018
2018 Roles of the mitochondrial genetics in cancer metastasis: not to be ignored any longer 2018
2018 Mitochondrial – nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivo 2018
2018 Reply to shah et al. 2018
2018 Automated quantitative image analysis for ex vivo metastasis assays reveals differing lung composition requirements for metastasis suppression by KISS1 2018
2017 Mitochondrial haplotype alters mammary cancer tumorigenicity and metastasis in an oncogenic driver–dependent manner 2017
2017 Mitochondrial genomic backgrounds affect nuclear DNA methylation and gene expression 2017
2017 Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy 2017
2017 Mitochondrial toxicity of tobacco smoke and air pollution 2017
2017 Vascular endothelial mitochondrial function predicts death or pulmonary outcomes in preterm infants 2017
2017 The KISS1 metastasis suppressor appears to reverse the Warburg effect by shifting from glycolysis to mitochondrial beta-oxidation 2017
2017 Gd2O3-doped silica @ Au nanoparticles for in vitro imaging cancer biomarkers using surface-enhanced Raman scattering 2017
2017 Mitochondrial DNA mutations and cardiovascular disease 2017
2017 Genome-wide in vivo RNAi screen identifies ITIH5 as a metastasis suppressor in pancreatic cancer 2017
2017 Mitophagy and mitochondrial biogenesis in atrial tissue of patients undergoing heart surgery with cardiopulmonary bypass. 2017
2017 Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis 2017
2016 Generation of Mitochondrial-nuclear eXchange Mice via Pronuclear Transfer. 2016
2016 Suppression of pancreatic cancer growth and metastasis by HMP19 identified through genome-wide shRNA screen 2016
2016 Targeting the untargetable? Nodal expression in TNBC 2016
2016 Tumor cell invasion-not all barriers are created equal 2016
2016 Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease 2016
2016 Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry 2016
2016 Cyclin-dependent kinase-mediated phosphorylation of breast cancer metastasis suppressor 1 (BRMS1) affects cell migration 2016
2016 Tumor heterogeneity - A 'contemporary concept' founded on historical insights and predictions 2016
2015 In vitro biophysical, microspectroscopic and cytotoxic evaluation of metastatic and non-metastatic cancer cells in responses to anti-cancer drug 2015
2015 Essential components of cancer education 2015
2015 Mitochondrial genetics regulate breast cancer Tumorigenicity and Metastatic potential 2015
2015 Mitochondrial-nuclear DNA mismatch matters 2015
2015 Bioenergetic programming of macrophages by the apolipoprotein A-I mimetic peptide 4F 2015
2015 MTBP inhibits migration and metastasis of hepatocellular carcinoma 2015
2015 Crocetinic acid inhibits hedgehog signaling to inhibit pancreatic cancer stem cells 2015
2014 An ex-vivo model for evaluating bioenergetics in aortic rings 2014
2014 Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix 2014
2014 Aging and energetics' 'Top 40' future research opportunities 2010-2013 2014
2014 Toward a drug development path that targets metastatic progression in osteosarcoma 2014
2014 Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice 2014
2014 Metastasis suppressor KISS1Seemsto reverse the warburg effect by enhancing mitochondrial biogenesis 2014
2014 Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing 2014
2014 A method for assessing mitochondrial bioenergetics in whole white adipose tissues 2014
2014 Breast cancer metastasis suppressor-1 promoter methylation in cell-free DNA provides prognostic information in non-small cell lung cancer. 2014
2014 Imaging of epidermal growth factor receptor on single breast cancer cells using surface-enhanced Raman spectroscopy 2014
2014 Metastasis suppressors in breast cancers: Mechanistic insights and clinical potential 2014
2014 Microenvironmental Influences on Metastasis Suppressor Expression and Function during a Metastatic Cell’s Journey 2014
2014 Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas 2014
2014 The Bioenergetic Health Index: a new concept in mitochondrial translational research. 2014
2013 Erratum: Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload (Biochemical Journal (2013) 455 (157-167)) 2013
2013 Xanthine oxidase inhibition preserves left ventricular systolic but not diastolic function in cardiac volume overload 2013
2013 MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-Mesenchymal transition (EMT) phenotype and are highly invasive in Vitro 2013
2013 Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload 2013
2013 BRSM1 promoter methylation provides prognostic information in primary breast tumors 2013
2013 Mitochondrial Bioenergetics of Metastatic Breast Cancer Cells in Response to Dynamic Changes in Oxygen Tension: Effects of HIF-1α 2013
2013 Developmental Exposure to Second-Hand Smoke Increases Adult Atherogenesis and Alters Mitochondrial DNA Copy Number and Deletions in apoE-/- Mice 2013
2013 Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood 2013
2013 Unraveling the 'TGF-β paradox' one metastamir at a time 2013
2013 The C-Terminal Putative Nuclear Localization Sequence of BReast cancer Metastasis Suppressor 1, BRMS1, Is Necessary for Metastasis Suppression 2013
2013 Beyond retrograde and anterograde signalling: Mitochondrial-nuclear interactions as a means for evolutionary adaptation and contemporary disease susceptibility 2013
2013 Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: Implications for mitochondrial therapeutics 2013
2013 MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4 2013
2013 Mitochondrial genetics and obesity: Evolutionary adaptation and contemporary disease susceptibility 2013
2012 Integration of cellular bioenergetics with mitochondrial quality control and autophagy 2012
2012 Preface 2012
2012 Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis 2012
2012 Clinical significance of KISS1 protein expression for brain invasion and metastasis 2012
2012 Ubiquitous Brms1 expression is critical for mammary carcinoma metastasis suppression via promotion of apoptosis 2012
2012 Clinical and biological significance of KISS1 expression in prostate cancer 2012
2012 Cytoplasmic BRMS1 expression in malignant melanoma is associated with increased disease-free survival 2012
2012 Subsets of ATP-sensitive potassium channel (K ATP) inhibitors increase gap junctional intercellular communication in metastatic cancer cell lines independent of sur expression 2012
2011 Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload 2011
2011 Protein signatures in human MDA-MB-231 breast cancer cells indicating a more invasive phenotype following knockdown of human endometase/matrilysin-2 by siRNA 2011
2011 3,5-bis(2,4-difluorobenzylidene)-4-piperidone, a novel compound that affects pancreatic cancer growth and angiogenesis 2011
2011 Unraveling the enigmatic complexities of BRMS1-mediated metastasis suppression 2011
2011 The mitochondrial paradigm for cardiovascular disease susceptibility and cellular function: A complementary concept to Mendelian genetics 2011
2011 Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines 2011
2011 Mitochondrial oxidative stress significantly influences atherogenic risk and cytokine induced oxidant production 2011
2011 Metastasis suppressors and the tumor microenvironment 2011
2011 Role of reactive oxygen species in injury-induced insulin resistance 2011
2011 Prognostic significance of BRMS1 expression in human melanoma and its role in tumor angiogenesis 2011
2011 Loss of interstitial collagen causes structural and functional alterations of cardiomyocyte subsarcolemmal mitochondria in acute volume overload 2011
2011 Metastasis suppressor genes. At the interface between the environment and tumor cell growth 2011
2011 Pre-osteoblastic MC3T3-E1 cells promote breast cancer growth in bone in a murine xenograft model 2011
2010 Homotypic gap junctional communication associated with metastasis suppression increases with PKA activity and is unaffected by PI3K inhibition 2010
2010 KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model 2010
2010 Perinatal tobacco smoke exposure increases vascular oxidative stress and mitochondrial damage in non-human primates 2010
2010 Modulation of mammary cancer cell migration by 15-deoxy-Δ 12,14-prostaglandin J2: Implications for anti-metastatic therapy 2010
2010 The KISS1 metastasis suppressor: A good night kiss for disseminated cancer cells 2010
2010 Linking metastasis suppression with metastamir regulation 2010
2009 Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4 2009
2009 Breast cancer metastasis suppressor 1 coordinately regulates metastasis-associated microRNA expression 2009
2009 Metastamir: The field of metastasis-regulatory microRNA is spreading 2009
2009 Linking metastasis suppression with metastamiR regulation 2009
2009 Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells 2009
2009 A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers 2009
2009 Nuclear magnetic resonance and circular dichroism study of metastin (Kisspeptin-54) structure in solution 2009
2009 Pulmonary ozone exposure induces vascular dysfunction, mitochondrial damage, and atherogenesis 2009
2009 Preclinical drug development must consider the impact on metastasis 2009
2009 Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone 2009
2009 Over-expression of the BRMS1 family member SUDS3 does not suppress metastasis of human cancer cells 2009
2009 Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE-/- mouse: Implications for a "multihit" hypothesis of fatty liver disease 2009
2009 BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-κB binding site of the uPA promoter 2009
2009 Breast cancer metastasis suppressor 1 up-regulates miR-146, Which suppresses breast cancer metastasis 2009
2009 Multiple forms of BRMS1 are differentially expressed in the MCF10 isogenic breast cancer progression model 2009
2009 Metastasis of hormone receptor positive breast cancer 2009
2008 Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs 2008
2008 Metastasis suppressors and the tumor microenvironment 2008
2008 Epigenetic silencing contributes to the loss of BRMS1 expression in breast cancer 2008
2008 New insights into the role of CXCR4 in prostate cancer metastasis 2008
2008 New insights into the role of CXCR4 in prostate cancer metastasis 2008
2008 Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling 2008
2008 Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1 2008
2008 Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells 2008
2008 Metastasis suppressors genes in cancer 2008
2008 BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process 2008
2008 Osteoprotegrin and the bone homing and colonization potential of breast cancer cells 2008
2007 A MSC-ing link in metastasis? 2007
2007 Effect of alcohol and tobacco smoke on mtDNA damage and atherogenesis 2007
2007 Microarray analysis reveals potential mechanisms of BRMS1-mediated metastasis suppression 2007
2007 C16 laminin peptide increases angiotropic extravascular migration of human melanoma cells in a shell-less chick chorioallantoic membrane assay 2007
2007 Breast cancer progression: Controversies and consensus in the molecular mechanisms of metastasis and EMT 2007
2007 Metastasis suppressors and their roles in breast carcinoma 2007
2007 The role of tobacco smoke induced mitochondrial damage in vascular dysfunction and atherosclerosis 2007
2007 Metastasis: recent discoveries and novel treatment strategies 2007
2007 Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy 2007
2007 Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation 2007
2007 Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease 2007
2006 Do we need to redefine a cancer metastasis and staging definitions? 2006
2006 Loss of breast cancer metastasis suppressor 1 protein expression predicts reduced disease-free survival in subsets of breast cancer patients 2006
2006 S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver 2006
2006 Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone 2006
2006 Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells 2006
2006 Metastasis suppressor proteins: Discovery, molecular mechanisms, and clinical application 2006
2006 Angiotropism of human melanoma: Studies involving in transit and other cutaneous metastases and the chicken chorioallantoic membrane - Implications for extravascular melanoma invasion and metastasis 2006
2006 Suppression of murine mammary carcinoma metastasis by the murine ortholog of breast cancer metastasis suppressor 1 (Brms1) 2006
2006 Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435 2006
2006 Kinetics of metastatic breast cancer cell trafficking in bone 2006
2006 The KISS1 metastasis suppressor: Mechanistic insights and clinical utility 2006
2006 The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase 2006
2006 Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer 2006
2006 Pathogenesis of osteopenia/osteoporosis induced by highly active anti-retroviral therapy for AIDS 2006
2005 Environmental contributions to cardiovascular disease: Particulates and ozone 2005
2005 Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis 2005
2005 Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment 2005
2005 Mitochondrial dysfunction in cardiovascular disease 2005
2005 Breast cancer metastasis suppressor 1 inhibits gene expression by targeting nuclear factor-κB activity 2005
2005 Reactive species-mediated regulation of cell signaling and the cell cycle: The role of MAPK 2005
2005 Differential effects of exercise on aortic mitochondria 2005
2005 Metastasis suppression by breast cancer metastasis suppressor 1 involves reduction of phosphoinositide signaling in MDA-MB-435 breast carcinoma cells 2005
2005 Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture. 2005
2004 Prenatal environmental tobacco smoke exposure promotes adult atherogenesis and mitochondrial damage in apolipoprotein E-/- mice fed a chow diet 2004
2004 Breast cancer cells induce osteoblast apoptosis: A possible contributor to bone degradation 2004
2004 Breast cancer metastatic potential: Correlation with increased heterotypic gap junctional intercellular communication between breast cancer cells and osteoblastic cells 2004
2004 A small molecule antagonist of the αυβ 3 integrin suppresses MDA-MB-435 skeletal metastasis 2004
2004 Identification of metastasis-associated proteins through protein analysis of metastatic MDA-MB-435 and metastasis-suppressed BRMS1 transfected-MDA-MB-435 cells 2004
2004 Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity 2004
2004 Capsaicin-mediated Denervation of Sensory Neurons Promotes Mammary Tumor Metastasis to Lung and Heart 2004
2004 Microarrays bring new insights into understanding of breast cancer metastasis to bone 2004
2004 Breast Cancer Metastasis Suppressor 1 (BRMS1) Forms Complexes with Retinoblastoma-binding Protein 1 (RBP1) and the mSin3 Histone Deacetylase Complex and Represses Transcription 2004
2004 Pericyte-Like Location of GFP-Tagged Melanoma Cells: Ex Vivo and in Vivo Studies of Extravascular Migratory Metastasis 2004
2003 Reduction of infarct size by short-term pretreatment with atorvastatin 2003
2003 Metastasis suppressor pathways - An evolving paradigm 2003
2003 Effects of α-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice 2003
2003 MDA-MB-435 human breast carcinoma metastasis to bone 2003
2003 Erratum: Mucosally-derived HPV-40 can infect both human genital foreskin and cutaneous hand skin tissues grafted into athymic mice (Virus Research (2003) 93 (109-114)) 2003
2003 A new member of the growing family of metastasis suppressors identified in prostate cancer 2003
2003 A potential role for gap junctions in breast cancer metastasis to bone 2003
2003 The skeleton as a unique environment for breast cancer cells 2003
2003 Genetic background is an important determinant of metastatic potential [2] 2003
2003 Mucosally-derived HPV-40 can infect both human genital foreskin and cutaneous hand skin tissues grafted into athymic mice 2003
2003 Breast cancer metastasis suppressor 1: Update 2003
2003 KISS1 metastasis suppression and emergent pathways 2003
2003 Breast cancer metastasis to bone: Evolving models and research challenges 2003
2003 Melanoma metastasis suppression by chromosome 6: Evidence for a pathway regulated by CRSP3 and TXNIP 2003
2003 Clinical & Experimental Metastasis: Introduction 2003
2003 Clinical and Experimental Metastasis: Introduction 2003
2002 Maintaining GFP tissue fluorescence through bone decalcification and long-term storage 2002
2002 DNA sequence analysis of interlocus recombination between the human T-cell receptor gamma variable (GV) and beta diversity-joining (BD/BJ) sequences on chromosome 7 (inversion 7) 2002
2002 B16F10 melanoma cell colonization of mouse lung is enhanced by partial pneumonectomy 2002
2002 Mitochondrial integrity and function in atherogenesis 2002
2002 Comparative sequence analysis in eight inbred strains of the metastasis modifier QTL candidate gene Brms1 2002
2002 Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells 2002
2002 Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues 2002
2002 Cu/Zn superoxide dismutase plays a role in angiogenesis 2002
2002 Suppression of human melanoma metastasis by the metastasis suppressor gene, BRMS1 2002
2001 Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1 2001
2001 Analysis of mechanisms underlying BRMS1 suppression of metastasis 2001
2001 Breast cancer progression and metastasis: Experimental studies and clinical translation 2001
2001 Genetic basis of human breast cancer metastasis 2001
2001 Aging, oxidative responses, and proliferative capacity in cultured mouse aortic smooth muscle cells 2001
2001 Breast cancer metastatic potential correlates with a breakdown in homospecific and heterospecific gap junctional intercellular communication 2001
2001 Suppression of C8161 melanoma metastatic ability by chromosome 6 induces differentiation-associated tyrosinase and decreases proliferation on adhesion-restrictive substrates mediated by overexpression of p21WAF1 and down-regulation of bcl-2 and cyclin D3 2001
2000 Dipeptidyl peptidase IV (DPPIV) inhibits cellular invasion of melanoma cells 2000
2000 Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis 2000
2000 The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines 2000
2000 Metastasis-suppressor genes: A review and perspective on an emerging field 2000
2000 Defining the biologic role of genes that regulate prostate cancer metastasis 2000
2000 Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13 2000
2000 A human melanoma metastasis-suppressor locus maps to 6q16.3-q23 2000
2000 Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells 2000
2000 Transfection of constitutively active mitogen-activated protein/extracellular signal-regulated kinase kinase confers tumorigenic and metastatic potentials to NIH3T3 cells 2000
1999 Metastasis-suppressed C8161 melanoma cells arrest in lung but fail to proliferate 1999
1999 Increased protein kinase Cδ in mammary tumor cells: Relationship to transformation and metastatic progression 1999
1999 What defines a useful marker of metastasis in human cancer? 1999
1999 Protein kinase C δ involvement in mammary tumor cell metastasis 1999
1999 Antioxidant vitamins: Sorting out the good and the not so good 1999
1999 Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells 1999
1999 Hydrogen peroxide induces oxidative DNA damage in rat type II pulmonary epithelial cells 1999
1998 Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1) 1998
1998 Genetic and epigenetic regulation of human breast cancer progression and metastasis 1998
1998 In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma 1998
1998 Human melanoma metastasis is inhibited following ex vivo treatment with an antisense oligonucleotide to protein kinase C-α 1998
1998 Correlation between reduction of metastasis in the MDA-MB-435 model system and increased expression of the kai-1 protein 1998
1997 KAII, a putative marker for metastatic potential in human breast cancer 1997
1997 Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display 1997
1997 Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (Nm23) 1997
1997 Technical considerations for studying cancer metastasis in vivo 1997
1997 Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1 1997
1997 Elevated expression of the neutrophil calcium-binding protein, MRP-14, in metastasis-enhancing neutrophils 1997
1996 Mitochondrial genome damage associated with cigarette smoking 1996
1996 Metastasis suppressed, but tumorigenicity and local invasiveness unaffected, in the human melanoma cell line MelJuSo after introduction of human chromosomes 1 or 6 1996
1996 Suppression of MDA-MB-435 breast carcinoma cell metastasis following the introduction of human chromosome 11 1996
1996 p53-independent increase in p21WAF1 and reciprocal down-regulation of cyclin A and proliferating cell nuclear antigen in bromodeoxyuridine-mediated growth arrest of human melanoma cells 1996
1996 KiSS-1, a novel human malignant melanoma metastasis-suppressor gene 1996
1996 Molecular mechanisms controlling human melanoma progression and metastasis 1996
1995 SOD2 (MnSOD) does not suppress tumorigenicity or metastasis of human melanoma C8161 cells 1995
1995 The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells 1995
1995 Mitochondrial DNA mutations in human degenerative diseases and aging 1995
1995 Suppression of human melanoma metastasis by introduction of chromosome 6 may be partially due to inhibition of motility, but not to inhibition of invasion 1995
1995 Highly metastatic 13762NF rat mammary adenocarcinoma cell clones stimulate bone marrow by secretion of granulocyte-macrophage colony-stimulating factor/interleukin-3 activity 1995
1995 Maternally transmitted diabetes and deafness 1995
1994 Evidence for paracrine regulation of experimental metastasis in 13762NF rat mammary adenocarcinoma cell clones 1994
1994 Mitochondrial myopathy with anemia, cardiomyopathy, and lactic acidosis: A distinct late onset mitochondrial disorder 1994
1994 Enhanced metastatic ability of TNF-α-treated malignant melanoma cells is reduced by intercellular adhesion molecule-1 (ICAM-1, CD54) antisense oligonucleotides 1994
1994 Is Tumor Cell Radiation Resistance Correlated with Metastatic Ability? 1994
1994 Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity 1994
1994 Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity 1994
1994 Mitochondrial DNA Mutations in Epilepsy and Neurological Disease 1994
1994 Mitochondrial Myopathies: Genetic Aspects 1994
1994 Mitochondrial diabetes revisited 1994
1993 U-77,863: a novel cinnanamide isolated from Streptomyces griseoluteus that inhibits cancer invasion and metastasis 1993
1993 The use of monozygotic and dizygotic twins to estimate the effects of inheritance on the levels of immunoglobulin isotypes and antibodies to phosphocholine 1993
1992 Coexpression of vimentin and keratins by human melanoma tumor cells: Correlation with invasive and metastatic potential 1992
1992 Allozyme and mitochondrial DNA analysis of a hybrid zone between white-tailed deer and mule deer (Odocoileus) in west texas 1992
1992 Erratum: Southeast Asian mitochondrial DNA analysis reveals genetic continuity of ancient Mongoloid migrations (Genetics (1992) 130 (139-152)) 1992
1992 Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion 1992
1992 Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion 1992
1992 Southeast Asian mitochondrial DNA analysis reveals genetic continuity of ancient mongoloid migrations 1992
1992 Subacute necrotizing encephalopathy: Oxidative phosphorylation defects and the ATPase 6 point mutation 1992
1991 The structure of human mitochondrial DNA variation 1991
1991 Rupture of the ascending aorta after surgical resection for lung cancer--a case report. 1991
1991 Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell line 1991
1991 Human melanoma cell invasion is inhibited in vitro by swainsonine and deoxymannojirimycin with a concomitant decrease in collagenase IV expression 1991
1991 Inhibition of Tumor Cell Invasion by Verapamil 1991
1990 Tumor progression- and metastasis-associated proteins identified using a model of locally recurrent rat mammary adenocarcinomas 1990
1990 Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNALys mutation 1990
1990 Amerindian mitochondrial DNAs have rare Asian mutations at high frequencies, suggesting they derived from four primary maternal lineages 1990
1990 Quantitation of human melanoma, carcinoma and sarcoma tumor cell adhesion to lymphatic endothelium 1990
1990 Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential 1990
1990 Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential 1990
1989 Neutrophil-mediated transfer of polar substances from liposomes to mammary tumor cells in vitro 1989
1989 Comparison of tumor cell invasion assays: human amnion versus reconstituted basement membrane barriers 1989
1989 Experimental model for locally recurring mammary tumors. Development, morphology, karyotype, growth kinetics, and experimental metastatic potential 1989
1989 Tumor-elicited polymorphonuclear cells, in contrast to 'normal' circulating polymorphonuclear cells, stimulate invasive and metastatic potentials of rat mammary adenocarcinoma cells 1989
1989 Use of the membrane invasion culture system (mics) as a screen for anti‐invasive agents 1989
1988 Development and Characterization of a Rat Model for Locally Recurring Mammary Tumors: Sensitivities to 5-Fluoro-2’-deoxyuridine, Adriamycin, and X-Irradiation 1988
1988 Growth of Rat Mammary Adenocarcinoma Cells in Semisolid Clonogenic Medium Not Correlated with Spontaneous Metastatic Behavior: Heterogeneity in the Metastatic, Antigenic, Enzymatic, and Drug Sensitivity Properties of Cells from Different Sized Colonies 1988
1988 Sensitivity of locally recurrent rat mammary tumour cell lines to syngeneic polymorphonuclear cell, macrophage and natural killer cell cytolysis 1988
1988 The role of polymorphonuclear leukocytes (PMN) on the growth and metastatic potential of 13762nf mammary adenocarcinoma cells 1988
1987 Biologic considerations for drug targeting in cancer patients 1987
1987 Degradation of Basement Membrane Type IV Collagen and Lung Subendothelial Matrix by Rat Mammary Adenocarcinoma Cell Clones of Differing Metastatic Potentials 1987
1987 Short communication: Rat mammary adenocarcinoma heat-stress proteins in vivo 1987
1986 Basement membrane degradative enzymes as possible markers of tumor metastasis. 1986
1986 Heat stress proteins and experimental cancer metastasis 1986
1986 Mitochondrial DNA analysis of hybridization between sympatric white-tailed deer and mule and deer in west Texas 1986
1985 Preferential organ attachment and invasion in vitro by B16 melanoma cells selected for differing metastatic colonization and invasive properties 1985
1985 Implications of tumor progression on clinical oncology 1985
1985 Preferential organ adhesion and invasion by B16 melanoma cells selected for differing metastatic colonization properties 1985
1984 Chromosome and DNA analyses of rat 13762NF mammary adenocarcinoma cell lines and clones of different metastatic potentials 1984
1984 Multiple phenotypic divergence of mammary adenocarcinoma cell clones - I. In vitro and in vivo properties 1984
1984 Multiple phenotypic divergence of mammary adenocarcinoma cell clones. - II. Sensitivity to radiation, hyperthermia and FUdR 1984
1983 Comparison of 'spontaneous' and 'experimental' metastasis using rat 13762 mammary adenocarcinoma metastatic cell clones 1983
1983 Phenotypic drift and heterogeneity in response of metastatic mammary adenocarcinoma cell clones to Adriamycin, 5-fluoro-2′-deoxyuridine and methotrexate treatment in vitro 1983
1983 Heterogeneous response and clonal drift of sensitivities of metastatic 13762nf mammary adenocarcinoma clones to ϒ-radiation in vitro 1983
1982 Development and biologic properties of malignant cell sublines and clones of a spontaneously metastasizing rat mammary adenocarcinoma 1982


Year Title Altmetric
2016 Preface.  Ed. 132.  2016


Year Title Altmetric
2019 The second genome: Effects of the mitochondrial genome on cancer progression.  63-105. 2019
2016 Beyond the primary tumor: Progression, invasion, and metastasis.  203-216. 2016
2016 Breast Cancer Metastasis Suppressor 1 (BRMS1): Robust Biological and Pathological Data, But Still Enigmatic Mechanism of Action.  111-137. 2016
2014 Invasion and Metastasis 2014
2013 Reactive Oxygen and Nitrogen Species: Interactions with Mitochondria and Pathophysiology.  17-22. 2013
2008 Invasion and Metastasis.  253-264. 2008

Investigator On

  • Glycosylation-dependent Mechanisms Regulating Ovarian Tumor cell Phenotype  awarded by National Cancer Institute/NIH/DHHS 2019 - 2024
  • UAB Diabetes Research Center  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2023
  • Comparative Energetics and Aging  awarded by National Institute on Aging/NIH/DHHS 2015 - 2020
  • Comparative Energetics and Aging - Comparative Molecular Energetics Analysis Core D  awarded by National Institute on Aging/NIH/DHHS 2015 - 2020
  • Comparative Energetics and Aging - Comparative Molecular Energetics Analysis Core D  awarded by National Institute on Aging/NIH/DHHS 2015 - 2019
  • Race - Adiposity Interactions Regulate Mechanisms Determining Insulin Sensitivity  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2013 - 2019
  • Apical Trans-Membrane Electron Transport Drives ELF Reducing Capacity  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2015 - 2018
  • UAB Diabetes Research Center  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2013 - 2018
  • Restore Energy Capacity in the Aging Heart  awarded by National Institute on Aging/NIH/DHHS 2017 - 2018
  • Lumina III System for UAB Optical Imaging  awarded by NIH - OFFICE OF THE DIRECTOR 2016 - 2017
  • Mitochondrial Haplotype Influences LV Dysfunction in Heart Failure  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2012 - 2017
  • Alcoholic Liver Dysfunction Potentiation by Hyperlipidemia and Cigarette Smoke  awarded by National Institute on Alcohol Abuse and Alcoholism/NIH/DHHS 2009 - 2016
  • The Role of PPARdelta Signaling in Diabetic Cardiomyopathy  awarded by American Diabetes Association, Inc. 2012 - 2016
  • Training Program in Cardiovascular Pathophysiology  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2015
  • The Role of the Mitochondrial Protein Thiol Modification in Endothelial Dysfunction  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2010 - 2015
  • UAB Diabetes Research and Training Center  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2008 - 2013
  • UAB Diabetes Research and Training Center - Administrative Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2008 - 2013
  • Teaching Activities

  • GBS758 - Cardiovascular Biology (Summer Term 2020) 2020
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2019) 2019
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2018) 2018
  • GBS758 - Cardiovasculaar Biology (Summer Term 2018) 2018
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2017) 2017
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2016) 2016
  • GBS758 - Cardiovasculaar Biology (Summer Term 2016) 2016
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2015) 2015
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2014) 2014
  • GBS758 - Cardiovasculaar Biology (Summer Term 2014) 2014
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2013) 2013
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2012) 2012
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2011) 2011
  • PAT777 - Autospy Experience (Spring Term 2011) 2011
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2010) 2010
  • IBS709 - New Perspective in Cardio Bio (Summer Term 2010) 2010
  • PAT777 - Autospy Experience (Spring Term 2010) 2010
  • PAT798 - Doc Level Non-Dissertation Res (Summer Term 2009) 2009
  • PAT752 - Lab Rotation Pathology (Summer Term 2008) 2008
  • PAT778 - Cardiovascular Biology (Summer Term 2008) 2008
  • PAT798 - Doc Level Non-Dissertation Res (Summer Term 2008) 2008
  • PAT730 - Lab Rotation (Spring Term 2008) 2008
  • PAT752 - Lab Rotation Pathology (Spring Term 2008) 2008
  • PAT790 - Spec Topics (Doctoral Level) (Spring Term 2008) 2008
  • PAT798 - Doc Level Non-Dissertation Res (Spring Term 2008) 2008
  • PAT799 - Doc Lev Dissertation Research (Spring Term 2008) 2008
  • PAT703 - Intro to Pathology Research (Fall Term 2007) 2007
  • PAT730 - Lab Rotation (Fall Term 2007) 2007
  • PAT790 - Spec Topics (Doctoral Level) (Fall Term 2007) 2007
  • PAT798 - Doc Level Non-Dissertation Res (Fall Term 2007) 2007
  • PAT799 - Doc Lev Dissertation Research (Fall Term 2007) 2007
  • Education And Training

  • Doctor of Philosophy in Biochemistry, Emory University 1993
  • Master of Science in Fishing and Fisheries Sciences and Management, Texas A&M University System : College Station 1987
  • Bachelor of Science or Mathematics in Zoology / Animal Biology, Texas A&M University System : College Station 1983
  • Full Name

  • Scott Ballinger