Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling.Cell Communication and Signaling.  16:61. 2018
2018 Emerging role of circadian clock disruption in alcohol-induced liver disease.AJP - Gastrointestinal and Liver Physiology.  315:G364-G373. 2018
2018 REVIEW ARTICLE: Cellular Abnormalities and Emerging Biomarkers in Alcohol Associated Liver Disease.Gene Expression: International Journal of Molecular and Cellular Science2018
2018 Genetic deletion of the circadian clock transcription factor BMAL1 and chronic alcohol consumption differentially alter hepatic glycogen in mice.AJP - Gastrointestinal and Liver Physiology.  314:G431-G447. 2018
2016 Identification of Small Molecule Inhibitors of Human Cytochrome c Oxidase That Target Chemoresistant Glioma Cells.Journal of Biological Chemistry.  291:24188-24199. 2016
2016 The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease.Redox Biology.  9:188-197. 2016
2016 Physiological processes underlying organ injury in alcohol abuse.AJP - Endocrinology and Metabolism.  311:E605-E619. 2016
2016 Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism.AJP - Heart and Circulatory Physiology.  310:H1520-H1532. 2016
2015 Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice.BBA - Biochimica et Biophysica Acta.  1861:1579-1595. 2015
2015 The Molecular Circadian Clock and Alcohol-Induced Liver Injury.Biomolecules.  5:2504-2537. 2015
2015 Chronic ethanol consumption disrupts diurnal rhythms of hepatic glycogen metabolism in mice.AJP - Gastrointestinal and Liver Physiology.  308:G964-G974. 2015
2015 Inhalation exposure model of hydrogen sulfide (H₂S)-induced hypometabolism in the male Sprague-Dawley rat.Methods in Enzymology.  555:19-35. 2015
2014 The Bioenergetic Health Index: a new concept in mitochondrial translational research.Clinical Science.  127:367-373. 2014
2014 Circadian regulation of metabolism.Journal of Endocrinology.  222:R75-R96. 2014
2014 Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice.Biochemical Journal.  461:223-232. 2014
2014 Involvement of the mitochondrial permeability transition pore in chronic ethanol-mediated liver injury in mice.AJP - Gastrointestinal and Liver Physiology.  306:G265-G277. 2014
2014 Ozone inhalation modifies the rat liver proteome.Redox Biology.  2:52-60. 2014
2014 Proteomic analysis of 4-hydroxynonenal (4-HNE) modified proteins in liver mitochondria from chronic ethanol-fed rats.Redox Biology.  2:1038-1047. 2014
2013 Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics.Biochemical Society Transactions.  41:127-133. 2013
2013 Chronic ethanol consumption disrupts the core molecular clock and diurnal rhythms of metabolic genes in the liver without affecting the suprachiasmatic nucleus.PLoS ONE.  8:e71684. 2013
2013 Redox Biology of Hydrogen Sulfide: Implications for Physiology, Pathophysiology, and Pharmacology.Redox Biology.  1:32-39. 2013
2012 Reply to Haouzi and Van de LouwJournal of applied physiology: respiratory, environmental and exercise physiology.  113:515. 2012
2012 Metabolic and cardiac signaling effects of inhaled hydrogen sulfide and low oxygen in male rats.Journal of applied physiology: respiratory, environmental and exercise physiology.  112:1659-1669. 2012
2012 Elucidating nature's solutions to heart, lung, and blood diseases and sleep disorders.Circulation Research.  110:915-921. 2012
2012 Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome.International Journal of Hepatology.  2012:962183. 2012
2011 Nitric oxide and hypoxia exacerbate alcohol-induced mitochondrial dysfunction in hepatocytes.BBA - Biochimica et Biophysica Acta.  1807:1573-1582. 2011
2011 Chronic exposure to a high-fat diet induces hepatic steatosis, impairs nitric oxide bioavailability, and modifies the mitochondrial proteome in mice.Antioxidants and Redox Signaling.  15:447-459. 2011
2011 Emerging role of redox dysregulation in alcoholic and nonalcoholic fatty liver disease.Antioxidants and Redox Signaling.  15:421-424. 2011
2010 Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain.Journal of Biological Chemistry.  285:39759-39767. 2010
2010 Chronic ethanol consumption enhances sensitivity to Ca(2+)-mediated opening of the mitochondrial permeability transition pore and increases cyclophilin D in liver.AJP - Gastrointestinal and Liver Physiology.  299:G954-G966. 2010
2010 What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology.Journal of Biological Chemistry.  285:19699-19704. 2010
2010 Advancing alcohol biomarkers research.Alcoholism: Clinical and Experimental Research.  34:941-945. 2010
2010 Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection.AJP - Gastrointestinal and Liver Physiology.  298:G732-G745. 2010
2010 Assessment of mitochondrial dysfunction arising from treatment with hepatotoxicants.Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.].  Chapter 14:Unit14.8. 2010
2010 Detection of protein thiols in mitochondrial oxidative phosphorylation complexes and associated proteins.Methods in Enzymology.  474:83-108. 2010
2009 Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE(-/-) mouse: implications for a "multihit" hypothesis of fatty liver disease.Free Radical Biology and Medicine.  46:928-938. 2009
2009 High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo.Biochemical Journal.  417:183-193. 2009
2008 Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease.Methods in Molecular Biology.  447:369-380. 2008
2008 Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases.Free Radical Biology and Medicine.  44:1259-1272. 2008
2008 Mitochondrial protein thiol modifications in acetaminophen hepatotoxicity: effect on HMG-CoA synthase.Toxicology Letters.  177:188-197. 2008
2008 Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease.Methods in Molecular Biology.  447:369-380. 2008
2007 Effect of alcohol and tobacco smoke on mtDNA damage and atherogenesis.Free Radical Biology and Medicine.  43:1279-1288. 2007
2007 Novel interactions of mitochondria and reactive oxygen/nitrogen species in alcohol mediated liver disease.World Journal of Gastroenterology.  13:4967-4973. 2007
2006 S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver.AJP - Gastrointestinal and Liver Physiology.  291:G857-G867. 2006
2006 Chronic ethanol consumption decreases mitochondrial and glycolytic production of ATP in liver.Alcohol and Alcoholism.  41:254-260. 2006
2005 Nitroxia: the pathological consequence of dysfunction in the nitric oxide-cytochrome c oxidase signaling pathway.Free Radical Biology and Medicine.  38:297-306. 2005
2005 Mitochondrial proteomics in free radical research.Free Radical Biology and Medicine.  38:175-188. 2005
2004 The role of iNOS in alcohol-dependent hepatotoxicity and mitochondrial dysfunction in mice.Hepatology.  40:565-573. 2004
2004 Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity.Journal of Biological Chemistry.  279:22092-22101. 2004
2004 Oxidative modification of hepatic mitochondria protein thiols: Effect of chronic alcohol consumptionAJP - Gastrointestinal and Liver Physiology.  286. 2004
2004 Oxidative modification of hepatic mitochondria protein thiols: effect of chronic alcohol consumption.AJP - Gastrointestinal and Liver Physiology.  286:G521-G527. 2004
2003 Chronic alcohol consumption increases the sensitivity of rat liver mitochondrial respiration to inhibition by nitric oxide.Hepatology.  38:141-147. 2003
2003 A review of the role of reactive oxygen and nitrogen species in alcohol-induced mitochondrial dysfunction.Free Radical Research.  37:585-596. 2003
2002 Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol.Archives of Biochemistry and Biophysics.  405:65-72. 2002
2002 Effects of alcohol and oxidative stress on liver pathology: the role of the mitochondrion.Alcoholism: Clinical and Experimental Research.  26:907-915. 2002
2002 Contribution of mitochondria to oxidative stress associated with alcoholic liver disease.Free Radical Biology and Medicine.  32:11-16. 2002
2001 Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver.Alcoholism: Clinical and Experimental Research.  25:726-733. 2001
2001 Ethanol and oxidative stress.Alcoholism: Clinical and Experimental Research.  25:237S-243S. 2001
2001 Ethanol consumption and liver mitochondria function.Neurosignals.  10:271-282. 2001
2000 Antioxidants and gadolinium chloride attenuate hepatic parenchymal and endothelial cell injury induced by low flow ischemia and reperfusion in perfused rat livers.Free Radical Research.  32:497-506. 2000
2000 Effect of low flow ischemia-reperfusion injury on liver function.Life Sciences.  66:1033-1044. 2000
1999 Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III.Free Radical Biology and Medicine.  27:891-900. 1999
1999 Effect of dietary fat on chronic ethanol-induced oxidative stress in hepatocytes.Alcoholism: Clinical and Experimental Research.  23:1210-1218. 1999
1998 Acute and chronic ethanol increases reactive oxygen species generation and decreases viability in fresh, isolated rat hepatocytes.Hepatology.  28:1318-1326. 1998
1997 Comparison of salicylate and D-phenylalanine for detection of hydroxyl radicals in chemical and biological reactions.Redox Report.  3:17-22. 1997
1996 Potential antioxidant function of xanthine oxidase in low flow ischemia-reperfusionFederation proceedings.  10. 1996
1994 Oxygen radical formation in well-washed rat liver microsomes: spin trapping studies.Free Radical Research.  20:51-60. 1994

Chapter

Year Title Altmetric
2004 Role of Oxidative Stress in Alcohol-Induced Mitochondrial Dysfunction.  1153-1173. 2004

Teaching Activities

  • GBS707 - Basic Biochem/Metabolism (Fall Term 2018) 2018
  • GBS749 - Mitochondria (Spring Term 2018) 2018
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2017) 2017
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2016) 2016
  • GBS749 - Special Topics Biomed Sci IV (Spring Term 2016) 2016
  • GBS749 - Special Topics Biomed Sci IV (Spring Term 2014) 2014
  • ENH799 - Dissertation Research (Fall Term 2012) 2012
  • ENH699 - Masters Level Project Res (Summer Term 2012) 2012
  • ENH799 - Dissertation Research (Summer Term 2012) 2012
  • ENH706 - Mitochondria Hlth DiseaseTox (Spring Term 2012) 2012
  • ENH799 - Dissertation Research (Spring Term 2012) 2012
  • ENH799 - Dissertation Research (Fall Term 2011) 2011
  • GBS704 - Intro to Experimental Med (Fall Term 2011) 2011
  • ENH799 - Dissertation Research (Summer Term 2011) 2011
  • ENH799 - Dissertation Research (Spring Term 2011) 2011
  • ENH799 - Dissertation Research (Fall Term 2010) 2010
  • ENH799 - Dissertation Research (Summer Term 2010) 2010
  • IBS706 - Mito Basis of Human Disease (Summer Term 2010) 2010
  • IBS798 - Non-Dissertation research (Summer Term 2010) 2010
  • ENH799 - Dissertation Research (Spring Term 2010) 2010
  • IBS701 - Pathophy/Pharmacology of Dis (Spring Term 2010) 2010
  • IBS798 - Non-Dissertation research (Spring Term 2010) 2010
  • ENH799 - Dissertation Research (Fall Term 2009) 2009
  • IBS798 - Non-Dissertation research (Fall Term 2009) 2009
  • ENH799 - Dissertation Research (Summer Term 2009) 2009
  • IBS706 - Mito Basis of Human Disease (Summer Term 2009) 2009
  • IBS798 - Non-Dissertation research (Summer Term 2009) 2009
  • ENH799 - Dissertation Research (Spring Term 2009) 2009
  • IBS701 - Pathophy/Pharmacology of Dis (Spring Term 2009) 2009
  • IBS798 - Non-Dissertation research (Spring Term 2009) 2009
  • ENH790 - Current Topics in ENH Res Sem (Fall Term 2008) 2008
  • ENH796 - Environ Hlth Sci Resrch (Fall Term 2008) 2008
  • ENH799 - Dissertation Research (Fall Term 2008) 2008
  • IBS798 - Non-Dissertation research (Fall Term 2008) 2008
  • ENH799 - Dissertation Research (Summer Term 2008) 2008
  • IBS706 - Mito Basis of Human Disease (Summer Term 2008) 2008
  • ENH790 - Current Topics in ENH Res Sem (Spring Term 2008) 2008
  • ENH798 - Doctoral Level Directed Res (Spring Term 2008) 2008
  • ENH790 - Current Topics in ENH Res Sem (Fall Term 2007) 2007
  • ENH798 - Doctoral Level Directed Res (Fall Term 2007) 2007
  • Education And Training

  • Bachelor of Science or Mathematics in Zoology / Animal Biology, University of Oklahoma
  • Doctor of Philosophy in Pharmacology, University of Oklahoma Health Sciences Center
  • Full Name

  • Shannon Bailey
  • Blazerid

  • sbailey