Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Phosgene inhalation causes hemolysis and acute lung injury 2019
2019 Erythrocyte and plasma oxidative stress appears to be compensated in patients with sickle cell disease during a period of relative health, despite the presence of known oxidative agents 2019
2019 A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions 2019
2019 Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell 2019
2019 Older Blood Is Associated With Increased Mortality and Adverse Events in Massively Transfused Trauma Patients: Secondary Analysis of the PROPPR Trial 2019
2019 Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertension 2019
2019 The role of redox-dependent mechanisms in heme release from hemoglobin and erythrocyte hemolysates 2019
2019 Characterizing red blood cell age exposure in massive transfusion therapy: the scalar age of blood index (SBI) 2019
2019 Nitrite and nitrate chemical biology and signalling 2019
2018 Non-invasive analysis of stored red blood cells using diffuse resonance Raman spectroscopy 2018
2018 Older blood is associated with increased mortality and adverse events in massively transfused trauma patients: secondary analysis of the PROPPR trial 2018
2018 Role of common γ-Chain cytokines in lung interleukin-22 regulation after acute exposure to aspergillus fumigatus 2018
2018 Acute kidney injury during parvovirus B19-induced transient aplastic crisis in sickle cell disease 2018
2018 Potential biomarkers of tissue hypoxia during acute hemodilutional anemia in cardiac surgery: A prospective study to assess tissue hypoxia as a mechanism of organ injury 2018
2018 Things we “kNOw” and do not “kNOw” about pulmonary hypertension 2018
2018 Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study 2018
2018 Bromofatty aldehyde derived from bromine exposure and myeloperoxidase and eosinophil peroxidase modify GSH and protein 2018
2018 Characterization of storage-induced red blood cell hemolysis using Raman spectroscopy 2018
2018 Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016 2018
2017 Over-the-counter mouthwash use and risk of pre-diabetes/diabetes 2017
2017 The Matrikine Acetylated Proline-Glycine-Proline Couples Vascular Inflammation and Acute Cardiac Rejection 2017
2017 Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice 2017
2017 Measuring nitrate reductase activity from human and rodent tongues 2017
2017 Assuring hospital supply of fresh red blood cells for critically ill patients 2017
2017 Nitrite therapy prevents chlorine gas toxicity in rabbits 2017
2017 Validation of two point-of-care tests against standard lab measures of NO in saliva and in serum 2017
2016 Corrigendum to “Assessment of endothelial glycocalyx disruption in term parturients receiving a fluid bolus before spinal anesthesia: a prospective observational study” (International Journal of Obstetric Anesthesia (2014) 23 (330–334)(S0959289X14000843)(10.1016/j.ijoa.2014.06.001)) 2016
2016 Red blood cell transfusion and its effect on microvascular dysfunction in shock states 2016
2016 Absorbance and redox based approaches for measuring free heme and free hemoglobin in biological matrices 2016
2016 Formation of chlorinated lipids post-chlorine gas exposure 2016
2016 The role of red blood cell S-nitrosation in nitrite bioactivation and its modulation by leucine and glucose 2016
2016 Compartmentalization is key in limiting nitric oxide scavenging by cell-free hemoglobin 2016
2016 There is blood in the water: Hemolysis, hemoglobin, and heme in acute lung injury 2016
2016 Yes to "NO" host flora symbiosis 2016
2015 Predicting storage-dependent damage to red blood cells using nitrite oxidation kinetics, peroxiredoxin-2 oxidation, and hemoglobin and free heme measurements 2015
2015 A nitric oxide-releasing self-assembled peptide amphiphile nanomatrix for improving the biocompatibility of microporous hollow fibers 2015
2015 Inhaled nitric oxide therapy for extrapulmonary inflammation 2015
2015 Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage 2015
2015 The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability 2015
2015 Peroxiredoxin-2 recycling is inhibited during erythrocyte storage 2015
2015 Working with nitric oxide and hydrogen sulfide in biological systems 2015
2014 A novel model of chronic wounds: Importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity 2014
2014 Assessment of Endothelial glycocalyx disruption in term parturients receiving a fluid bolus before spinal anesthesia: a prospective observational study 2014
2014 Chlorine gas exposure disrupts nitric oxide homeostasis in the pulmonary vasculature 2014
2014 The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistula 2014
2014 Redox therapeutics in hepatic ischemia reperfusion injury 2014
2014 A randomized clinical trial testing the anti-inflammatory effects of preemptive inhaled nitric oxide in human liver transplantation 2014
2014 Mechanism of faster NO scavenging by older stored red blood cells 2014
2014 Increased sensitivity of Apolipoprotein E knockout mice to swainsonine dependent immunomodulation 2014
2014 Membrane attack complex generation increases as a function of time in stored blood 2014
2014 Nitrite therapy improves survival postexposure to chlorine gas 2014
2013 The level of complement activation fragments is higher in red blood cell units than segments 2013
2013 The deleterious effect of red blood cell storage on microvascular response to transfusion 2013
2013 Effects of erythrocyte aging on nitric oxide and nitrite metabolism 2013
2013 Targeting endothelial adhesion molecule mrna to control inflammation: Novel insights into potential anti-inflammatory effects of il-19. focus on "interleukin-19 decreases leukocyte-endothelial cell interactions by reduction in endothelial cell adhesion molecule mrna stability" 2013
2013 Identification of a high-mannose ICAM-1 glycoform: Effects of ICAM-1 hypoglycosylation on monocyte adhesion and outside in signaling 2013
2013 Endothelial heterogeneity and adhesion molecules N-glycosylation: Implications in leukocyte trafficking in inflammation 2013
2013 Erratum: Elevated levels of NO are localized to distal airways in asthma (Free Radical Biology and Medicine (2011) 50 (1679-1688)) 2013
2013 Role of the b93cys, ATP and adenosine in red cell dependent hypoxic vasorelaxation 2013
2013 Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo 2013
2013 Heterogenic endothelial responses to inflammation: role for differential N-glycosylation and vascular bed of origin. 2013
2013 Is methemoglobin an inert bystander, biomarker or a mediator of oxidative stress-the example of anemia? 2013
2012 Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype 2012
2012 Administration of nitrite after chlorine gas exposure prevents lung injury: Effect of administration modality 2012
2012 Nitric oxide formation versus scavenging: The red blood cell balancing act 2012
2012 Erythrocyte storage increases rates of NO and nitrite scavenging: Implications for transfusion-related toxicity 2012
2012 ABO Blood Group Is Associated with Response to Inhaled Nitric Oxide in Neonates with Respiratory Failure 2012
2012 Role of endothelial N-glycan mannose residues in monocyte recruitment during atherogenesis 2012
2012 Sodium nitrite protects against kidney injury induced by brain death and improves post-transplant function 2012
2012 Single-dose pharmacokinetics of different oral sodium nitrite formulations in diabetes patients 2012
2012 Metabolic and cardiac signaling effects of inhaled hydrogen sulfide and low oxygen in male rats 2012
2012 Encapsulation of hemoglobin inside liposomes surface conjugated with poly(ethylene glycol) attenuates their reactions with gaseous ligands and regulates nitric oxide dependent vasodilation 2012
2012 Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles 2012
2012 Microvascular response to red blood cell transfusion in trauma patients 2012
2011 Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands 2011
2011 A Role for Endothelial Mannose Residues in Inflammation Dependent Monocyte Adhesion Under Flow 2011
2011 Losing control over adenosine 5′-triphosphate release: Implications for the red blood cell storage lesion 2011
2011 Current perspectives and challenges in understanding the role of nitrite as an integral player in nitric oxide biology and therapy 2011
2011 Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling 2011
2011 Effects of T- and R-state stabilization on deoxyhemoglobin-nitrite reactions and stimulation of nitric oxide signaling 2011
2011 Elevated levels of NO are localized to distal airways in asthma 2011
2011 P75. The effects of red blood cell storage time on nitric oxide and nitrite-dependent signaling 2011
2011 Red blood cell age and potentiation of transfusion-related pathology in trauma patients 2011
2011 Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite 2011
2011 Acyloxy nitroso compounds as nitroxyl (HNO) donors: Kinetics, reactions with thiols, and vasodilation properties 2011
2011 The detection of the nitrite reductase and NO-generating properties of haemoglobin by mitochondrial inhibition 2011
2011 The potential role of the red blood cell in nitrite-dependent regulation of blood flow 2011
2011 Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress 2011
2010 Erythrocyte-dependent regulation of human skeletal muscle blood flow: Role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP 2010
2010 Isoflavones and PPAR signaling: A critical target in cardiovascular, metastatic, and metabolic disease 2010
2010 S-Nitrosothiol biology and therapeutic potential in metabolic disease 2010
2010 ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway 2010
2010 The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats 2010
2010 Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels 2010
2010 Potential for chlorine gas-induced injury in the extrapulmonary vasculature 2010
2010 Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway 2010
2010 Effects of T-state and R-state stabilization on Deoxyhemoglobin-nitrite Reactions and Stimulation of Nitric Oxide (NO) Signaling 2010
2010 Post–Cl2 Exposure Therapeutics Using Nitrite: Different Effects of IM vs. IP Administration 2010
2010 Role of Hemoglobin Beta93Cys as an Antioxidant in the Vascular Compartment: Implications for Vascular Homeostasis During Endotoxemia 2010
2010 The Effects of Red Blood Cell Storage Time on Nitric Oxide and Nitrite-dependent Signaling 2010
2009 Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction 2009
2009 A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury 2009
2009 Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation 2009
2009 Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38β MAPK-NF-κB pathway 2009
2009 Antioxidant Role of Hemoglobin Beta93 Cysteine in the Red Blood Cell and the Vascular Compartment 2009
2009 Developmental changes in circulating IL-8/CXCL8 isoforms in neonates 2009
2009 Hypoxic Nitrite Reduction to Nitric Oxide Varies by Cell Type 2009
2009 Nitrate and nitrite in biology, nutrition and therapeutics 2009
2009 Reply to 'Nitrite-methemoglobin inadequate for hypoxic vasodilation' 2009
2009 Sodium Nitrite Administration Mitigates Lung Injury After Chlorine Gas Exposure in Rats 2009
2008 Modulatory effects of hypercapnia on in vitro and in vivo pulmonary endothelial-neutrophil adhesive responses during inflammation 2008
2008 Preserving vessel function during ischemic disease: New possibilities of inorganic nitrite therapy 2008
2008 SNO-hemoglobin and hypoxic vasodilation 2008
2008 Dipyridamole promotes ischemia-induced angiogenesis and tissue blood flow in critical limb ischemia througha PKA dependent nitric oxide pathway 2008
2008 SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation 2008
2008 Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis 2008
2008 The role of red blood cells and hemoglobin-nitric oxide interactions on blood flow 2008
2008 Activation of Endothelial Nitric Oxide Synthase and Heme Oxygenase 1 Expression in Vasculature by Nitro-Fatty Acids 2008
2008 Chapter 9 Novel Method for Measuring S-Nitrosothiols Using Hydrogen Sulfide 2008
2008 Inhibition of CXCR2 and P38 signaling can block ECMO-related inflammation 2008
2008 Inhibition of CXCR2 and p38 signaling can block ECMO-related inflammation 2008
2007 Hydrogen sulfide mediates the vasoactivity of garlic 2007
2007 Hemoglobin oxygen fractional saturation regulates nitrite-dependent vasodilation of aortic ring bioassays 2007
2007 Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation 2007
2007 Sildenafil promotes ischemia-induced angiogenesis through a PKG-dependent pathway 2007
2007 Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor 2007
2007 Effects of venous needle turbulence during ex vivo hemodialysis on endothelial morphology and nitric oxide formation 2007
2007 Modulation of pulmonary endothelial endothelin B receptor expression and signaling: Implications for experimental hepatopulmonary syndrome 2007
2007 Hydrogen sulfide mediates vasoactivity in an O2-dependent manner 2007
2007 Pentoxifylline attenuation of experimental hepatopulmonary syndrome 2007
2007 Regulation of endothelial glutathione by ICAM-1 governs VEGF-A-mediated eNOS activity and angiogenesis 2007
2007 Anti-inflammatory effects of isoflavones are dependent on flow and human endothelial cell PPARγ 2007
2007 Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin 2007
2007 Deoxyhemoglobin possesses dual functions as NO scavenger and a nitrite dependent NO generator: Insights from oxygen controlled vessel bioassays 2007
2007 ICAM-1 cross-linking stimulates endothelial glutathione synthesis 2007
2007 ICAM-1 cytoplasmic tail regulates endothelial cell redox status through an NADPH oxidase pathway 2007
2007 Nitrite transport in erythrocytes: Evidence for oxygen-dependent modulation of export 2007
2006 Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators 2006
2006 Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation 2006
2006 Formation ofNitroso compounds in the reaction of nitrite and hemoglobin. 2006
2006 Hydrolysis of acyloxy nitroso compounds yields nitroxyl (HNO) 2006
2006 Effects of S-nitrosation on hemoglobin-induced microvascular damage 2006
2006 O27. Effects of inhaled nitric oxide on human orthotopic liver transplantation 2006
2006 Mechanisms of cystic fibrosis transmembrane conductance regulator activation by S-nitrosoglutathione 2006
2006 Effects of sodium nitrite on ischemia-reperfusion injury in the rat kidney 2006
2006 Regulation of endothelial intracellular glutathione by ICAM-1 2006
2006 ICAM-1 governs angiogenesis via redox regulation of PTEN expression and eNOS activity 2006
2006 Sildenafil enhances angiogenesis after mice hind limb ischemia independent of nitric oxide 2006
2006 Sildenafil enhances angiogenesis after mice Hindlimb ischemia 2006
2006 Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation 2006
2006 Chlorination modulates anti-inflammatory effects of isoflavones via PPAR gamma: Insights into the structure-activity relationships 2006
2006 Chronic administration of nitrite therapy protects blood flow in the murine hind limb ischemia induced angiogenesis model 2006
2006 Erratum: The emerging biology of the nitrite anion (Nature Chemical Biology (2005) 1, (308-314)) 2006
2006 Is S-nitrosohemoglobin dependent valsodilatation under allosteric control? Insights from a hemoglobin beta C93A mouse model 2006
2006 Nitrite uptake by erythrocytes: Insights into mechanism and regulation 2006
2006 Sildenafil enhances ischemia-induced angiogenesis independent of nitric oxide 2006
2006 The cytoplasmic tail of ICAM-1 regulates endothelial glutathione synthesis 2006
2005 ICAM-1 governs angiogenesis via regulation of eNOS activity: Role of glutathione and PTEN 2005
2005 Hemoglobin mediated nitrite activation of soluble guanylyl cyclase 2005
2005 The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. 2005
2005 Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control 2005
2005 Revealing anti-inflammatory mechanisms of soy isoflavones by flow: Modulation of leukocyte-endothelial cell interactions 2005
2005 Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues 2005
2005 Fatty acid transduction of nitric oxide signaling: Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor 2005
2005 Glutathione inhibits VEGF angiogenesis through an eNOS dependent pathway 2005
2005 Modulation of endothelial signaling and glycocalyx by isoflavones: Implications for inflammation 2005
2005 Assessing NO-dependent vasodilatation using vessel bioassays at defined oxygen tensions 2005
2005 Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver 2005
2005 Dietary modulation of vascular N-glycosylation: Mechanistic implications for anti-inflammatory effects of polyphenols 2005
2005 Metabolism of phytoestrogen conjugates 2005
2005 The Emerging Biology of the Nitrite Anion 2005
2005 The reaction between nitrite and hemoglobin: The role of nitrite in hemoglobin-mediated hypoxic vasodilation 2005
2004 The red blood cell and vascular function in health and disease 2004
2004 The red blood cell and vascular function in health and disease 2004
2004 Transduction of NO-bioactivity by the red blood cell in sepsis: Novel mechanisms of vasodilation during acute inflammatory disease 2004
2004 Weight loss and race modulate nitric oxide metabolism in overweight women 2004
2004 What's right about nitrite? 2004
2004 How do red blood cells dilate blood vessels?--Reply. 2004
2004 Nitrosative chemistry in the red blood cell: implications for the pathogenesis of sepsis 2004
2004 Regulation of endothelial glutathione by ICAM-1: Implications for inflammation 2004
2004 Vasoactivity of nitrite and erythrocytes supports a novel mechanism of hypoxic vasodilation 2004
2004 Intercellular Adhesion Molecule-1 (ICAM-1) Regulates Endothelial Cell Motility through a Nitric Oxide-dependent Pathway 2004
2004 Mechanisms of the interaction of nitroxyl with mitochondria 2004
2004 ICAM-1 regulates endothelial cell motility through an NO dependent pathway 2004
2004 Glutathione modulates VEGF angiogenic responses in an adhesion molecule dependent manner 2004
2004 The biochemistry of nitric oxide, nitrite, and hemoglobin: Role in blood flow regulation 2004
2004 The biochemistry of nitric oxide, nitrite, and hemoglobin: Role in blood flow regulation 2004
2004 L-Arginine inhibits xanthine oxidase-dependent endothelial dysfunction in hypercholesterolemia 2004
2004 Physiologic, pathologic and therapeutic implications for hemoglobin interactions with nitric oxide 2004
2004 Mechanistic re-examination of the reaction between nitrite and hemoglobin 2004
2004 Nitrite activation of sGC in blood 2004
2004 Redox signalling: From nitric oxide to oxidized lipids 2004
2004 Regulation of vascular function by haemoglobin 2004
2004 Simulation of the diffusion and reaction of nitric oxide produced within erythrocytes 2004
2003 Neutrophil myeloperoxidase chlorinates and nitrates soy isoflavones and enhances their antioxidant properties 2003
2003 Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation 2003
2003 Novel function of human hemoglobin as a nitrite reductase regulates nitric oxide homeostasis and hypoxic vasodilation. 2003
2003 Control of mitochondrial respiration by NO., Effects of low oxygen and respiratory state 2003
2003 Blood flow and SNOHb: an allosteric controversy 2003
2003 Mass spectrometric methods for the analysis of chlorinated and nitrated isoflavonoids: A novel class of biological metabolites 2003
2003 S-nitrosohemoglobin is distinguished from other nitrosovasodilators by unique oxygen-dependent responses that support an allosteric mechanism of action [4] (multiple letters) 2003
2003 S-nitrosothiols inhibit uterine smooth muscle cell proliferation independent of metabolism to NO and cGMP formation 2003
2003 S-nitrosothiols inhibit uterine smooth muscle cell proliferation independent of metabolism to NO and cGMP formation. 2003
2003 Vasoactivity of S-nitrosohemoglobin: Role of oxygen, heme, and NO oxidation states 2003
2003 Cytoprotection against oxidative stress and the regulation of glutathione synthesis 2003
2003 Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects 2003
2002 Bromination, Chlorination, and Nitration of Isoflavonoids 2002
2002 Effects of S-nitrosation and cross-linking of hemoglobin on hypoxic pulmonary vasoconstriction in isolated rat lungs 2002
2002 Nanotransducers in cellular redox signaling: Modification of thiols by reactive oxygen and nitrogen species 2002
2002 Haemoglobin: NO transporter, NO inactivator or NOne of the above? 2002
2002 Activation of c-Jun N-terminal kinase and apoptosis in endothelial cells mediated by endogenous generation of hydrogen peroxide 2002
2002 Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: Protection against quinone-mediated oxidative stress 2002
2002 Associations of weight loss and race with plasma NO3-/NO2-and 3-nitrotyrosine 2002
2002 Measurement of mitochondrial respiratory thresholds and the control of respiration by nitric oxide 2002
2002 Obesity, aerobic exercise, and vascular disease: The role of oxidant stress 2002
2001 Essential role of ICAM-1 in mediating monocyte adhesion to aortic endothelial cells 2001
2001 Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease 2001
2001 Antioxidant mechanisms of isoflavones in lipid systems: Paradoxical effects of peroxyl radical scavenging 2001
2001 Endothelial NOS-dependent activation of c-Jun NH(2)- terminal kinase by oxidized low-density lipoprotein. 2001
2001 Endothelial NOS-dependent activation of c-Jun NH2-terminal kinase by oxidized low-density lipoprotein 2001
2001 Endothelial NOS-dependent activation of c-Jun NH2-terminal kinase by oxidized low-density lipoprotein 2001
2001 Essential role of ICAM-1 in mediating monocyte adhesion to aortic endothelial cells. 2001
2001 Protein kinase B/Akt activates c-Jun NH2-terminal kinase by increasing NO production in response to shear stress 2001
2001 Formation of nanomolar concentrations of S-nitroso-albumin in human plasma by nitric oxide 2001
2001 Soy isoflavonoids and cancer - Metabolism at the target site 2001
2001 Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase 2001
2001 Enhanced antioxidant activity after chlorination of quercetin by hypochlorous acid 2001
2001 Monocyte adhesion to ICAM-1 deficient mouse aortic endothelium: Differential requirements for ICAM-1 in response to oxidized LDL and TNF-[alpha] 2001
2001 Anti-inflammatory effects of soy-isoflavones: Inhibition of leukocyte-endothelial interactions 2001
2001 Cytoprotection mediated by oxidized lipids in endothelial cells 2001
2001 Formation of novel bioactive metabolites from the reactions of pro-inflammatory oxidants with polyphenolics 2001
2001 Glutathione nitroso-sulfoxide: a potential reaction product of glutathione and peroxynitrite 2001
2001 Mechanisms of cell signaling by nitric oxide and peroxynitrite: From mitochondria to MAP kinases 2001
2001 Mitochondrial sensitivity to nitric oxide is dependent on respiratory state 2001
2001 Non-heme iron enhances the induction of glutamate-cysteine ligase and heme oxygenase-1 by nitric oxide in human endothelial cells 2001
2001 Redox reactions of hemoglobin and myoglobin: Biological and toxicological implications 2001
2001 Regulation of endothelial cell redox status by ICAM-1: Identification of a novel pathway governing endothelial cell reactivity 2001
2000 Reaction of S-nitrosoglutathione with the heme group of deoxyhemoglobin 2000
2000 Mechanisms of the pro- and anti-oxidant actions of nitric oxide in atherosclerosis 2000
2000 Cell signaling by reactive nitrogen and oxygen species in atherosclerosis 2000
2000 Biochemical aspects of the reaction of hemoglobin and NO: Implications for Hb-based blood substitutes 2000
2000 Beyond ERα and ERβ: Estrogen receptor binding is only part of the isoflavone story 2000
2000 Isoflavonoids and chronic disease: Mechanisms of action 2000
1999 A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure 1999
1999 Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase. 1999
1999 Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH2-terminal kinase 1999
1999 Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH2-terminal kinase 1999
1999 Chlorination and nitration of soy isoflavones 1999
1999 Biochemical characterization of human S-nitrosohemoglobin. Effects on oxygen binding and transnitrosation 1999
1999 Biological aspects of reactive nitrogen species 1999
1999 The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: A role for γ-glutamylcysteine synthetase and γ-glutamyl transpeptidase 1999
1999 A critical appraisal of hydrogen peroxide and superoxide as signaling molecules using the JNK/SAPK map kinase pathway 1999
1999 Antioxidant properties of phytoestrogens 1999
1999 Is endothelium relaxing factor nitric oxide or an S-nitrosothiol? Insights from scavenging by hemoglobin 1999
1999 Molecular mechanisms of the copper dependent oxidation of low-density lipoprotein 1999
1999 Molecular mechanisms of the copper dependent oxidation of low-density lipoprotein - Invited commentary 1999
1999 Nitric oxide donor generation from reactions of peroxynitrite 1999
1999 Shear stress simulates cJUN N-terminal kinase (JNK) by activation of PI-3-kinase (PI3K), Akt and endothelial NO synthase (eNOS). 1999
1998 Nitric oxide-dependent induction of glutathione synthesis through increased expression of γ-glutamylcysteine synthetase 1998
1998 Nitrosation of uric acid by peroxynitrite: Formation of a vasoactive nitric oxide donor 1998
1998 Making and working with peroxynitrite. 1998
1998 Pathophysiology of nitric oxide and related species: Free radical reactions and modification of biomolecules 1998
1998 S-nitrosation of hemoglobin: Effects on O-2 delivery and antioxidant properties 1998
1997 Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol 1997
1997 The globin-based free radical of ferryl hemoglobin is detected in normal human blood 1997
1997 Reduction of Cu(II) by lipid hydroperoxides: Implications for the copper-dependent oxidation of low-density lipoprotein 1997
1997 Nitric oxide, free radicals and cell signalling in cardiovascular disease 1997
1997 The interplay of nitric oxide and peroxynitrite with signal transduction pathways: Implications for disease 1997
1996 Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper 1996
1996 An EPR investigation of human methaemoglobin oxidation by hydrogen peroxide: Methods to quantify all paramagnetic species observed in the reaction 1996
1996 Redox cycling of human methaemoglobin by H2O2 yields persistent ferryl iron and protein based radicals 1996
1996 Using peroxynitrite as oxidant with low-density lipoprotein 1996
1995 Novel reactions of nitric oxide in biological systems 1995
1995 Pro-oxidant effects of cross-linked haemoglobins explored using liposome and cytochrome c oxidase vesicle model membranes 1995

Book

Year Title Altmetric
2008 Preface.  Ed. 61.  2008

Chapter

Year Title Altmetric
2017 S-Nitrosothiols and Nitric Oxide Biology.  45-56. 2017
2011 Biochemistry of Storage of Red Blood Cells.  231-241. 2011
2009 Nitric Oxide Regulation in Redox Signaling.  271-291. 2009
2008 The reaction between nitrite and hemoglobin. the role of nitrite in hemoglobin-mediated hypoxic vasodilation.  269-289. 2008
2003 The importance of in vivo metabolism of polyphenols and their biological actions.  51-59. 2003
2000 Cytoprotective mechanisms of nitric oxide: the role of cell signaling.  191-199. 2000

Investigator On

  • INvestigations In Gout, Hyperuricemia, and ComorbidiTies (INSIGHT) Center of Research Translation (CORT)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2017 - 2022
  • INvestigations In Gout, Hyperuricemia, and ComorbidiTies (INSIGHT) Center of Research Translation (CORT) - Project 4: Protecting Renal Function with Urate-Lowering Drugs  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2017 - 2022
  • CIALIS® Reverses Halogen Induced Injury to Pregnant Animals and Their Offspring  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2016 - 2021
  • Bromine Inhalation Induced Lung Injury: Novel Mechanisms and Treatment Strategies  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2015 - 2020
  • Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease.  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2020
  • Saturated Fatty Acid-Induced Autophagy in Vascular Endothelium  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2016 - 2020
  • Prohealing Multifunctional Endothelium Nanomatrix Coated Stent  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2015 - 2019
  • Glycocalyx Mechanoregulation of Anglopoietln-2 and Post-Traumatic Lung Injury  awarded by DOD - Department of Defense 2018 - 2019
  • UAB Statistical Genetics Post-Doctoral Training Program  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2013 - 2019
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2017 - 2018
  • Private Grant  awarded by HEART BIOTECH HOLDINGS, LLC 2015 - 2017
  • Mechanisms and Countermeasures of Halogen-Induced Injury to Pregnant Mice  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2015 - 2016
  • Training Program in Cardiovascular Pathophysiology  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2015
  • The Role of the Mitochondrial Protein Thiol Modification in Endothelial Dysfunction  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2010 - 2015
  • Mitochondrial Mechanisms of Hydrogen Sulfide-Induced Suspended Animation  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2009 - 2014
  • Teaching Activities

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  • PAT798 - Doc Level Non-Dissertation Res (Spring Term 2012) 2012
  • PAT799 - Doc Lev Dissertation Research (Spring Term 2012) 2012
  • HMG707 - Vocab in Clinical Research (Fall Term 2011) 2011
  • PAT798 - Doc Level Non-Dissertation Res (Fall Term 2011) 2011
  • PAT799 - Doc Lev Dissertation Research (Fall Term 2011) 2011
  • PAT776 - Cancer Biology Journal Club (Summer Term 2011) 2011
  • PAT798 - Doc Level Non-Dissertation Res (Summer Term 2011) 2011
  • PAT799 - Doc Lev Dissertation Research (Summer Term 2011) 2011
  • HMG705 - Vocabulary in Drug Discovery (Spring Term 2011) 2011
  • PAT798 - Doc Level Non-Dissertation Res (Spring Term 2011) 2011
  • PAT799 - Doc Lev Dissertation Research (Spring Term 2011) 2011
  • PAT798 - Doc Level Non-Dissertation Res (Fall Term 2010) 2010
  • PAT799 - Doc Lev Dissertation Research (Fall Term 2010) 2010
  • PAT798 - Doc Level Non-Dissertation Res (Summer Term 2010) 2010
  • PAT799 - Doc Lev Dissertation Research (Summer Term 2010) 2010
  • PAT730 - Lab Rotation (Spring Term 2010) 2010
  • PAT790 - Spec Topics (Doctoral Level) (Spring Term 2010) 2010
  • PAT798 - Doc Level Non-Dissertation Res (Spring Term 2010) 2010
  • PAT799 - Doc Lev Dissertation Research (Spring Term 2010) 2010
  • PAT790 - Spec Topics (Doctoral Level) (Fall Term 2009) 2009
  • PAT798 - Doc Level Non-Dissertation Res (Fall Term 2009) 2009
  • PAT799 - Doc Lev Dissertation Research (Fall Term 2009) 2009
  • PAT799 - Doc Lev Dissertation Research (Summer Term 2009) 2009
  • PAT730 - Lab Rotation (Spring Term 2009) 2009
  • PAT752 - Lab Rotation Pathology (Spring Term 2009) 2009
  • PAT790 - Spec Topics (Doctoral Level) (Spring Term 2009) 2009
  • PAT798 - Doc Level Non-Dissertation Res (Spring Term 2009) 2009
  • PAT799 - Doc Lev Dissertation Research (Spring Term 2009) 2009
  • PAT703 - Intro to Pathology Research (Fall Term 2008) 2008
  • PAT730 - Lab Rotation (Fall Term 2008) 2008
  • PAT790 - Spec Topics (Doctoral Level) (Fall Term 2008) 2008
  • PAT798 - Doc Level Non-Dissertation Res (Fall Term 2008) 2008
  • PAT799 - Doc Lev Dissertation Research (Fall Term 2008) 2008
  • IBS700 - Biological Chem/Cell Physiol (Fall Term 2007) 2007
  • NEUR711 - Princ of Cell Neurosci-Mod I (Fall Term 2007) 2007
  • Full Name

  • Rakesh Patel