13C NMR assignments of conforma‐tionally defined 6‐s‐trans‐retinoids

Academic Article

Abstract

  • A new class of vitamin A analogs (retinoids) was synthesized containing a dimethylene bridge to maintain a 6‐s‐trans conformation of the terminal double bonds. The 1H and 13C NMR spectra were assigned for 15 new compounds, including E‐Z isomers (all‐E, 13Z, 9Z and 9Z,13Z) of retinoids containing an ethyl ester and car‐boxylic acid polar end groups, and also the (all‐E)‐isomer of the retinoids with an alcohol and aldehyde polar end‐groups and five C15 intermediates. The assignments were based on long‐range 1H13C heteronuclear 2D experiments. Copyright © 1995 John Wiley & Sons Ltd.
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    Digital Object Identifier (doi)

    Author List

  • Vaezi MF; Brouillette WJ; Muccio DD
  • Start Page

  • 497
  • End Page

  • 499
  • Volume

  • 33
  • Issue

  • 6