Efficacy of rapid IV administration of valproic acid for status epilepticus.

Academic Article

Abstract

  • Although not approved by the US Food and Drug Administration for the treatment of status epilepticus (SE), valproic acid (VPA) is an emerging option for this purpose. The authors reviewed 63 patients (30 men) with SE treated with IV VPA (average dose, 31.5 mg/kg). Analysis of demographic, clinical, and treatment information indicated an overall efficacy of 63.3% and favorable tolerance of rapid administration.
  • Authors

    Published In

  • Neurology  Journal
  • Keywords

  • Anticonvulsants, Comorbidity, Drug Administration Schedule, Drug Evaluation, Female, Humans, Infusions, Intravenous, Male, Middle Aged, Retrospective Studies, Status Epilepticus, Treatment Outcome, Valproic Acid
  • Digital Object Identifier (doi)

    Author List

  • Limdi NA; Shimpi AV; Faught E; Gomez CR; Burneo JG
  • Start Page

  • 353
  • End Page

  • 355
  • Volume

  • 64
  • Issue

  • 2