Update on Clinical Guidelines for Treatment of Hypertension

Academic Article


  • The 2014 US Hypertension Guideline (JNC 8) differs from many other contemporary guidelines. It is focused on the 3 most important questions in hypertension management: (1) When to initiate treatment? (2) How low should you go? (3) How do you get there? It takes a rigorous approach, based on evidence from randomized controlled trials (RCTs) with important health outcomes, the gold standard for determining efficacy and effectiveness of medical treatments. To facilitate implementation, treatment goals are simplified. The goal (BP <140/90 mm Hg) is the same for all hypertensive adults except when RCT evidence supports different goals for a particular subpopulation, ie, <150/90 mm Hg for those over age 60 without chronic kidney disease (CKD) or diabetes. Four medication classes, ACEI, ARB, CCB, or thiazide-type diuretic, alone or in combination, are recommended as initial therapy, except when evidence indicates a preference for a specific class, as in racial and CKD subgroups.
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    Author List

  • Oparil S
  • Start Page

  • 1
  • End Page

  • 8
  • Volume

  • 8
  • Issue

  • 11