Epigenetics of Personalized Medicine

Chapter

Abstract

  • Interindividual variability in epigenetic processes is often formed through environmental influences that shape the epigenome, and these epigenetic signatures can be translated to assist disease prevention or therapy. Since epigenetic aberrations often span across the genome, analysis of the epigenome through computational epigenetics has gained increasing attention as a means to identify key epigenetic changes that allow diseases to form and progress. Many medical conditions have an epigenetic basis and are therefore amenable to management through personalized epigenetic analyses. Drug development, responses to changes in nutrition, toxicity, and forensics also have high potential for analysis of epigenetic signatures. It is apparent that personalized epigenetics is on the horizon of advances that could significantly improve the management of many disorders and diseases that are currently presenting persistent challenges to more conventional approaches to medicine.
  • Digital Object Identifier (doi)

    International Standard Book Number (isbn) 13

  • 9780124201354
  • Start Page

  • 3
  • End Page

  • 13