Purification, crystallization and preliminary crystallographic analysis of porcine aldose reductase

Academic Article

Abstract

  • Large crystals of porcine aldose reductase have been grown from polyethylene glycol solutions. The crystals are triclinic, space-group P1, with a = 81.3 A ̊, b = 85.9 A ̊, c = 56.6 A ̊, α = 102.3 °, β = 103.3 ° and ψ = 79.0 °. The crystals grow within ten days to dimensions of 0.6 mm × 0.4 mm × 0.2 mm and diffract to at least 2.5 Å. There are four molecules in the unit cell related by a set of three mutually perpendicular non-crystallographic 2-fold axes. © 1991.
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    Digital Object Identifier (doi)

    Author List

  • El-Kabbani O; Narayana SVL; Babu YS; Moore KM; Flynn TG; Petrash JM; Westbrook EM; DeLucas LJ; Bugg CE
  • Start Page

  • 695
  • End Page

  • 698
  • Volume

  • 218
  • Issue

  • 4