Recent developments in chemoradiotherapy for locally advanced cancer of the cervix.

Academic Article

Abstract

  • Patients with locally advanced cervical cancer comprise a significant proportion of the total population with cervical cancer, particularly in developing countries. The inability to control pelvic tumors is still a significant concern. Although neoadjuvant chemotherapy is associated with a high response rate, data from randomized trials clearly do not support the use of neoadjuvant chemotherapy prior to definitive irradiation. However, the results of concurrent cisplatin (Platinol)-based chemotherapy and radiotherapy are highly promising for locally advanced cancer of the cervix and should be considered as a treatment option. To decrease the risk of distant metastasis and improve survival, more effective drugs or drug combinations need to be developed.
  • Published In

  • Oncology  Journal
  • Keywords

  • Antineoplastic Agents, Cisplatin, Clinical Trials as Topic, Combined Modality Therapy, Female, Humans, Uterine Cervical Neoplasms
  • Author List

  • Kim RY; Alvarez RD
  • Start Page

  • 1327
  • End Page

  • 1335
  • Volume

  • 14
  • Issue

  • 9