Cystic kidney diseases: all roads lead to the cilium.

Academic Article

Abstract

  • Cystic kidney disorders are one of the leading causes of end-stage renal disease. Numerous experimental animal models have been used to understand the disease pathogenesis. Recent advancements in this field have provided a surprising finding: that many of the proteins associated with cystic kidney disease localize to a nearly forgotten organelle, the primary cilium.
  • Published In

    Keywords

  • Animals, Cilia, Epithelial Cells, Humans, Kidney Tubules, Polycystic Kidney, Autosomal Dominant
  • Digital Object Identifier (doi)

    Author List

  • Zhang Q; Taulman PD; Yoder BK
  • Start Page

  • 225
  • End Page

  • 230
  • Volume

  • 19