More Than Just the Postal Service: Novel Roles for IFT Proteins in Signal Transduction

Academic Article


  • Disruption of intraflagellar transport (IFT) results in loss of flagella and cilia as well as their signaling activity, making it difficult to assess possible roles of IFT in signal transduction. In a recent issue of Cell, Wang et al. (2006) used a temperature-sensitive IFT mutant to separate flagella assembly from signaling activity, and they show that IFT has a direct role in forming signaling complexes in the flagella. © 2006 Elsevier Inc. All rights reserved.
  • Published In

  • Developmental Cell  Journal
  • Digital Object Identifier (doi)

    Author List

  • Yoder BK
  • Start Page

  • 541
  • End Page

  • 542
  • Volume

  • 10
  • Issue

  • 5