Ca(2+)-Activated Cl(-) Channels: A Newly Emerging Anion Transport Family.

Academic Article

Abstract

  • A new family of Cl(-) channels widely expressed in epithelia has been identified. These proteins are associated with Ca(2+)-sensitive conductive Cl(-) transport when heterologously expressed. This family may underlie the Ca(2+)-mediated Cl(-) conductance responsible for rescue of the cystic fibrosis knockout mouse from significant airway disease.
  • Published In

    Author List

  • Fuller CM; Benos DJ
  • Start Page

  • 165
  • End Page

  • 171
  • Volume

  • 15