Ca2+-activated Cl- channels: A newly emerging anion transport family

Academic Article

Abstract

  • A new family of Cl- channels widely expressed in epithelia has been identified. These proteins are associated with Ca2+-sensitive conductive Cl- transport when heterologously expressed. This family may underlie the Ca2+-mediated Cl- conductance responsible for rescue of the cystic fibrosis knockout mouse from significant airway disease.
  • Author List

  • Fuller CM; Benos DJ
  • Start Page

  • 165
  • End Page

  • 171
  • Volume

  • 15
  • Issue

  • 4