Dwelling on T cell fate decisions

Academic Article

Abstract

  • Defining determinants of T cell fate is central to understanding adaptive immunity and the design of effective vaccines. Tubo et al. demonstrate that intrinsic properties of T cell receptor signaling dictate whether CD4 T cells adopt predominantly type 1 helper or follicular helper T cell phenotypes in response to bacterial or viral infection. © 2013 Elsevier Inc.
  • Published In

  • Cell  Journal
  • Digital Object Identifier (doi)

    Author List

  • Winstead CJ; Weaver CT
  • Start Page

  • 739
  • End Page

  • 741
  • Volume

  • 153
  • Issue

  • 4