Three-dimensional structure of the bacteriophage P22 tail machine

Academic Article

Abstract

  • The tail of the bacteriophage P22 is composed of multiple protein components and integrates various biological functions that are crucial to the assembly and infection of the phage. The three-dimensional structure of the P22 tail machine determined by electron cryo-microscopy and image reconstruction reveals how the five types of polypeptides present as 51 subunits are organized into this molecular machine through twelve-, six- and three-fold symmetry, and provides insights into molecular events during host cell attachment and phage DNA translocation. © 2005 European Molecular Biology Organization | All Rights Reserved.
  • Published In

  • EMBO Journal  Journal
  • Digital Object Identifier (doi)

    Author List

  • Tang L; Marion WR; Cingolani G; Prevelige PE; Johnson JE
  • Start Page

  • 2087
  • End Page

  • 2095
  • Volume

  • 24
  • Issue

  • 12