Insulin action and insulin resistance: Diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system

Academic Article


  • Insulin resistance is a primary abnormality in the evolution of type 2 diabetes and is associated with Syndrome X, a cluster of risk factors predisposing to cardiovascular disease. In the polycystic ovary syndrome, insulin resistance may lead to hyperandrogenism; troglitazone, an insulin sensitizer, corrects abnormalities in the pituitary/gonadal axis in these patients.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Hunter SJ; Garvey WT
  • Start Page

  • 331
  • End Page

  • 345
  • Volume

  • 105
  • Issue

  • 4