Inflammatory breast cancer: Advances in therapy

Academic Article


  • Inflammatory breast cancer is the most aggressive breast neoplasm and one of the most ominous solid tumors. Because of distinct clinical characteristics, diagnosis can usually be made on clinical grounds. Biopsy including the overlying skin may demonstrate dermal lymphatic invasion, although the absence of dermal lymphatic invasions should not deter aggressive therapy. Surgery or irradiation alone has little effect on the natural history of this disease since lymphatic invasion and distant metas‐tases are often present at presentation. Inflammatory breast cancer should be considered a systemic disease. Accordingly, aggressive combined modality therapy including multi‐drug chemotherapy, surgery, and irradiation have prolonged disease‐free survival and overall survival. Copyright © 1988 Wiley‐Liss, Inc., A Wiley Company
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Ellis LM; Bland KI; Copeland EM
  • Start Page

  • 261
  • End Page

  • 267
  • Volume

  • 4
  • Issue

  • 4