Comparison of saliva PCR assay versus rapid culture for detection of congenital cytomegalovirus infection.

Academic Article

Abstract

  • As part of the CMV and Hearing Multicenter Screening (CHIMES) study, 72,239 newborns were screened for cytomegalovirus by rapid culture and real-time PCR of saliva samples. Of the 266 infants with congenital cytomegalovirus infection, discordance between rapid culture and PCR was observed in 14 children, and 13 were identified only by PCR, demonstrating the superiority of the PCR assay.
  • Published In

    Keywords

  • Cytomegalovirus Infections, Humans, Infant, Newborn, Prospective Studies, Real-Time Polymerase Chain Reaction, Saliva, United States, Viral Load, Virology
  • Digital Object Identifier (doi)

    Author List

  • Pinninti SG; Ross SA; Shimamura M; Novak Z; Palmer AL; Ahmed A; Tolan RW; Bernstein DI; Michaels MG; S├ínchez PJ
  • Start Page

  • 536
  • End Page

  • 537
  • Volume

  • 34
  • Issue

  • 5