Obesity and mortality: Are the risks declining? Evidence from multiple prospective studies in the United States

Academic Article

Abstract

  • We evaluated whether the obesity-associated years of life lost (YLL) have decreased over calendar time. We implemented a meta-analysis including only studies with two or more serial body mass index (BMI) assessments at different calendar years. For each BMI category (normal weight: BMI 18.5 to <25 [reference]; overweight: BMI 25 to <30; grade 1 obesity: BMI 30 to <35; and grade 2-3 obesity: BMI≥35), we estimated the YLL change between 1970 and 1990. Because of low sample sizes for African-American, results are reported on Caucasian. Among men aged ≤60 years YLL for grade 1 obesity increased by 0.72 years (P<0.001) and by 1.02 years (P=0.01) for grade 2-3 obesity. For men aged >60, YLL for grade 1 obesity decreased by 1.02 years (P<0.001) and increased by 0.63 years for grade 2-3 obesity (P=0.63). Among women aged ≤60, YLL for grade 1 obesity decreased by 4.21 years (P<0.001) and by 4.97 years (P<0.001) for grade 2-3 obesity. In women aged >60, YLL for grade 1 obesity decreased by 3.98 years (P<0.001) and by 2.64 years (P=0.001) for grade 2-3 obesity. Grade 1 obesity's association with decreased longevity has reduced for older Caucasian men. For Caucasian women, there is evidence of a decline in the obesity YLL association across all ages. © 2014 World Obesity.
  • Published In

  • Obesity Reviews  Journal
  • Digital Object Identifier (doi)

    Author List

  • Mehta T; Fontaine KR; Keith SW; Bangalore SS; de los Campos G; Bartolucci A; Pajewski NM; Allison DB
  • Start Page

  • 619
  • End Page

  • 629
  • Volume

  • 15
  • Issue

  • 8