Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002.

Academic Article


  • In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.
  • Published In


  • Adult, Aged, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Female, HIV Infections, Humans, Male, Middle Aged, Neoplasms, Risk Factors
  • Digital Object Identifier (doi)

    Author List

  • Bedimo R; Chen RY; Accortt NA; Raper JL; Linn C; Allison JJ; Dubay J; Saag MS; Hoesley CJ
  • Start Page

  • 1380
  • End Page

  • 1384
  • Volume

  • 39
  • Issue

  • 9