Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus

Academic Article


  • © 2015 Centers for Disease Control and Prevention (CDC). All rights reserved. To investigate azole resistance in clinical Aspergillus isolates, we conducted prospective multicenter international surveillance. A total of 3,788 Aspergillus isolates were screened in 22 centers from 19 countries. Azole-resistant A. fumigatus was more frequently found (3.2% prevalence) than previously acknowledged, causing resistant invasive and noninvasive aspergillosis and severely compromising clinical use of azoles.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • van der Linden JWM; Arendrup MC; Warris A; Lagrou K; Pelloux H; Hauser PM; Chryssanthou E; Mellado E; Kidd SE; Tortorano AM
  • Start Page

  • 1041
  • End Page

  • 1044
  • Volume

  • 21
  • Issue

  • 6