Urodynamic characterization of obese women with urinary incontinence undergoing a weight loss program: the Program to Reduce Incontinence by Diet and Exercise (PRIDE) trial.

Academic Article

Abstract

  • The purpose of this study was to describe urodynamic characteristics of overweight or obese women with urinary incontinence and explore the relationship between urodynamic parameters, body mass index (BMI), and abdominal circumference (AC). One hundred ten women underwent a standardized cough stress test and urodynamic study. Eighty-six percent of women had urodynamic stress incontinence and 15% detrusor overactivity. Intra-abdominal pressure (Pabd) at maximum cystometric capacity (MCC) increased 0.4 cm H(2)O per kg/m(2) unit of BMI (95% confidence interval [CI] = 0.0,0.7, p = 0.04) and 0.4 cm H(2)O per 2 cm increase in AC (CI = 0.2, 0.7, p < 0.01). Intravesical pressure (Pves) at MCC increased 0.4 cm H(2)O per 2 cm increase in AC (CI = 0.0, 0.8, p = 0.05) but was not associated with BMI (p = 0.18). BMI and AC had a stronger association with Pabd than with Pves, suggesting a possible mechanism for the association between obesity and urinary incontinence.
  • Keywords

  • Aged, Body Mass Index, Comorbidity, Female, Humans, Middle Aged, Obesity, Urinary Incontinence, Urodynamics, Waist Circumference, Weight Loss
  • Digital Object Identifier (doi)

    Author List

  • Richter HE; Creasman JM; Myers DL; Wheeler TL; Burgio KL; Subak LL; Program to Reduce Incontinence by Diet and Exercise (PRIDE) Research Group
  • Start Page

  • 1653
  • End Page

  • 1658
  • Volume

  • 19
  • Issue

  • 12