Reduction in mitral regurgitation during therapy guided by measured filling pressures in the ESCAPE trial.

Academic Article


  • BACKGROUND: Dynamic mitral regurgitation (MR) contributes to decompensation in chronic dilated heart failure. Reduction of MR was the primary physiological end point in the ESCAPE trial, which compared acute therapy guided by jugular venous pressure, edema, and weight (CLIN) with therapy guided additionally by pulmonary artery catheters (PAC) toward pulmonary wedge pressure
  • Authors

    Published In


  • Adult, Aged, Body Weight, Catheterization, Swan-Ganz, Central Venous Pressure, Chronic Disease, Edema, Female, Heart Failure, Hemodynamics, Hospitalization, Humans, Jugular Veins, Male, Middle Aged, Mitral Valve Insufficiency, Patient Discharge, Predictive Value of Tests, Pulmonary Artery, Pulmonary Wedge Pressure, Stroke Volume, Time Factors, Treatment Outcome, United States, Ventricular Function, Left
  • Digital Object Identifier (doi)

    Author List

  • Palardy M; Stevenson LW; Tasissa G; Hamilton MA; Bourge RC; Disalvo TG; Elkayam U; Hill JA; Reimold SC; ESCAPE Investigators
  • Start Page

  • 181
  • End Page

  • 188
  • Volume

  • 2
  • Issue

  • 3