Zygomycosis over-infection during voriconazole therapy for aspergillosis in a heart transplant patient, successfully treated with liposomal amphotericin and posaconazole.

Academic Article

Abstract

  • Aspergillosis and zygomycosis are life-threatening fungal infections in immunocompromised patients. We report a heart transplant recipient with an early pulmonary invasive aspergillosis successfully treated with association of voriconazole and caspofungin. Zygomycosis sinusitis, which was diagnosed while he still was on voriconazole therapy, was successfully treated with the use of combination antifungal therapy including liposomal amphotericin plus posaconazole and conservative surgical debridement.
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    Published In

    Keywords

  • Amphotericin B, Antifungal Agents, Debridement, Drug Therapy, Combination, Heart Transplantation, Humans, Immunocompromised Host, Invasive Pulmonary Aspergillosis, Male, Middle Aged, Pyrimidines, Sinusitis, Treatment Outcome, Triazoles, Voriconazole, Zygomycosis
  • Digital Object Identifier (doi)

    Author List

  • Bourke P; Castro P; Rabagliati R; Beltran C; Verdejo H; Winter JL; Bourge RC
  • Start Page

  • E56
  • End Page

  • E59
  • Volume

  • 14
  • Issue

  • 5