A case-control study of leukemia among petroleum workers

Academic Article


  • This case-control study evaluates the relationship between leukemia and the work histories of active and retired employees of a large petroleum company. The study includes 69 cases with leukemia and 284 matched controls. Employment in production-related work in the oil and gas division was associated with myelogenous leukemia (odds ratio [OR] = 2.0, 95% confidence interval [CI] =.97 to 4.2) and particularly with acute myelogenous leukemia (OR = 2.8, 95% CI = 1.1 to 7.3). The association with acute myelogenous leukemia was strongest for subjects in the highest tertile (32 + years) of duration of employment in oil-and gas production-related work (OR = 8.7, 95% CI = 2.0 to 37), and there was a consistent trend of increasing ORs with increasing duration of employment (P =.01). No clear association was observed for refining division work and leukemia. This is the first epidemiologic study reporting a positive association between oil and gas field work and acute myelogenous leukemia. © by American College of Occupational and Environmental Medicine.
  • Digital Object Identifier (doi)

    Author List

  • Sathiakumar N; Delzell E; Cole P; Brill I; Frisch J; Spivey G
  • Start Page

  • 1269
  • End Page

  • 1277
  • Volume

  • 37
  • Issue

  • 11