Preference-based quality-of-life measures for neocortical epilepsy surgery.

Academic Article

Abstract

  • Critical to decision analysis studies are measures of outcome utilities. In epilepsy surgery the benefit versus risk ratio is of particular interest in neocortical resections. Using the standard gamble, we measured preferences of 30 epilepsy patients for 10 outcome states specific to neocortical epilepsy surgery. Although considered preliminary, the findings suggest that the value of being seizure-free may be greater than that of continued disabling seizures, even if some deficits typical of "eloquent" cortex injury are incurred with surgery. Seizure freedom achieved with polytherapy medical management may be less desirable than that achieved with surgery and monotherapy.
  • Published In

  • Epilepsia  Journal
  • Keywords

  • Adolescent, Adult, Aged, Anticonvulsants, Decision Support Techniques, Disease-Free Survival, Epilepsy, Female, Health Status, Humans, Male, Middle Aged, Models, Psychological, Neocortex, Patient Preference, Quality of Life, Risk Assessment, Surveys and Questionnaires, Treatment Outcome
  • Digital Object Identifier (doi)

    Author List

  • Knowlton RC; Kar J; Miller S; Limdi N; Elgavish R; Gilliam FG; Riley K; Howell J; Kilgore M
  • Start Page

  • 1018
  • End Page

  • 1020
  • Volume

  • 52
  • Issue

  • 5