Fat oxidation, lipolysis, and free fatty acid cycling in obesity-prone and obesity-resistant rats.

Academic Article

Abstract

  • Defects in fat metabolism may contribute to the development of obesity, but what these defects are and where they occur in the feeding/fasting cycle are unknown. In the present study, basal fat metabolism was characterized using a high-fat diet (HFD)-induced model of obesity development. Male rats consumed a HFD (45% fat, 35% carbohydrate) ad libitum for either 1 or 5 wk (HFD1 or HFD5). After 1 wk on the HFD, rats were separated on the basis of body weight gain into obesity-prone (OP, > or =48 g) or obesity-resistant (OR,
  • Authors

    Keywords

  • Adipocytes, Animals, Blood Glucose, Blood Urea Nitrogen, Body Weight, Calorimetry, Indirect, Cell Count, Cell Size, Dietary Fats, Energy Intake, Energy Metabolism, Esterification, Fats, Fatty Acids, Nonesterified, Glycerol, Lipolysis, Male, Norepinephrine, Obesity, Oxidation-Reduction, Pulmonary Gas Exchange, Rats, Triglycerides
  • Digital Object Identifier (doi)

    Pubmed Id

  • 18801482
  • Author List

  • Commerford SR; Pagliassotti MJ; Melby CL; Wei Y; Gayles EC; Hill JO
  • Start Page

  • E875
  • End Page

  • E885
  • Volume

  • 279
  • Issue

  • 4