Political and economic changes have created challenges for physician attrition rates in Ukraine. This study examined how a cross-section of Ukrainian physicians prioritised the factors hypothesised to influence decisions about continuing to work in medicine. A survey was conducted with 443 physicians in Ukraine. Latent class choice analysis (LCA) was used to model the heterogeneity in pair-wise comparisons of factors related to physician continued employment in medicine. The response rate was 70% (N = 310). Respondents, on average, were 45.4 years old, practiced 21.6 years. Four groups were identified on the basis of how they prioritised factors about work. Group 1 (47.7%) was ‘culture-focused’, group 2 (27.7%) was ‘advancement-focused’, group 3 (16.2%) was ‘routinisation-focused’, and group 4 (8.5%) was ‘externally-focused’. The use of a person-centred analytical approach represents an alternative for examining career decision issues that should be considered for subgroups within the workforce. © 2012 Inderscience Enterprises Ltd.